Clarithromycin combined with Loxonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumonia Hospitalization 5/20/2004 Female 73 lb 1/6/2006 Physician Japan
Primary
Secondary
Concomitant
Tuberculous Pleurisy Hospitalization 2/24/2005 Female 90 lb 1/23/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/10/2005 67 Male 143 lb 2/1/2006 Physician Japan
Primary
Secondary
White Blood Cell Count Increased Hospitalization 9/10/2005 67 Male 143 lb 2/24/2006 Physician Japan
Primary
Secondary
Joint Sprain Life Threatening 2/17/2006 90 Female 3/7/2006 Physician Japan
Primary
Concomitant
Joint Sprain Life Threatening 2/18/2006 90 Female 3/10/2006 Physician Japan
Primary
Concomitant
Rash Other Serious 11/28/2005 70 Male 3/16/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/20/2004 Female 73 lb 4/17/2006 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 3/2/2006 84 Female 4/12/2006 Physician Japan
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Hospitalization 10/26/2004 74 Male 150 lb 5/11/2006 Physician Japan
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 10/26/2004 74 Male 150 lb 5/25/2006 Physician Japan
Primary
Concomitant
Rash Other Serious 11/28/2005 70 Male 5/24/2006 Physician Japan
Primary
Secondary
Concomitant
Cryptogenic Organising Pneumonia Hospitalization 5/1/2006 60 Female 7/19/2006 Physician Japan
Primary
Concomitant
Cryptogenic Organising Pneumonia Hospitalization 5/1/2006 60 Female 97 lb 8/1/2006 Physician Japan
Primary
Concomitant
Leukoencephalopathy Other Serious 5/1/2006 46 Female 99 lb 9/11/2006 Physician Japan
Primary
Concomitant
Leukoencephalopathy Other Serious 5/1/2006 46 Female 99 lb 9/19/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 10/16/2004 Female 95 lb 10/10/2006 Physician Japan
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Hospitalization 10/26/2004 74 Male 150 lb 11/22/2006 Physician Japan
Primary
Concomitant
Cytomegalovirus Enterocolitis Hospitalization 7/1/2006 Female 119 lb 12/19/2006 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Enterocolitis Hospitalization 7/1/2006 Female 119 lb 1/18/2007 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 9/15/2006 77 Female 115 lb 3/16/2007 Other Health Professional Japan
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 3/1/2007 Female 3/22/2007 Physician Japan
Primary
Concomitant
Arthritis Bacterial Hospitalization 2/16/2007 Female 104 lb 4/17/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/7/2007 55 Male 93 lb 4/23/2007 Physician Japan
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 2/17/2007 28 Male 4/27/2007 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 4/16/2007 6 Female 4/27/2007 Pharmacist Japan
Primary
Secondary
Hallucination Life Threatening 2/18/2006 90 Female 5/3/2007 Physician Japan
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 2/17/2007 28 Male 5/7/2007 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 4/13/2007 6 Female 6/19/2007 Pharmacist Japan
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 3/2/2007 Female 73 lb 6/22/2007 Physician Japan
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 10/26/2004 74 Male 150 lb 6/22/2007 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 4/13/2007 6 Female 7/10/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Menorrhagia Hospitalization 6/26/2007 38 Female 112 lb 7/10/2007 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 3/2/2007 Female 73 lb 7/12/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/7/2007 55 Male 93 lb 11/7/2007 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/21/2006 Male 123 lb 11/9/2007 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 5/20/2004 Female 73 lb 11/12/2007 Physician Japan
Primary
Secondary
Concomitant
Oculomucocutaneous Syndrome Hospitalization 9/5/2007 65 Female 11/20/2007 Physician Japan
Primary
Concomitant
Oculomucocutaneous Syndrome Hospitalization 9/5/2007 65 Female 11/29/2007 Physician Japan
Primary
Concomitant
Oculomucocutaneous Syndrome Hospitalization 9/5/2007 65 Female 12/13/2007 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/2/2007 Female 119 lb 1/7/2008 Physician Japan
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 9/2/2007 Female 119 lb 2/12/2008 Physician Japan
Primary
Secondary
Sepsis Hospitalization 9/21/2006 Male 123 lb 3/12/2008 Physician Japan
Primary
Concomitant
Tuberculosis Hospitalization 3/10/2008 72 3/24/2008 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 6/14/2005 37 Female 4/2/2008 Consumer Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 3/7/2008 Male 104 lb 4/4/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 1/31/2008 Male 88 lb 4/11/2008 Physician Japan
Primary
Secondary
Concomitant
Cholestasis Hospitalization 3/16/2008 Male 119 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/24/2005 39 Female 106 lb 4/15/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/17/2007 46 Male 143 lb 4/16/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/17/2007 Male 143 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 3/7/2008 Male 104 lb 4/17/2008 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 6/14/2005 37 Female 4/29/2008 Consumer Japan
Primary
Secondary
Concomitant
Cholestasis Hospitalization 3/16/2008 Male 119 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 4/11/2007 Male 165 lb 6/5/2008 Physician Japan
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 4/1/2008 60 Female 6/5/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Vertebral Artery Occlusion Hospitalization 5/28/2008 Female 86 lb 6/18/2008 Physician Japan
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 4/11/2007 Male 165 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 4/3/2008 Female 6/30/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/7/2007 Male 143 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/17/2007 46 Male 143 lb 7/7/2008 Consumer United States
Primary
Secondary
Concomitant
Vertebral Artery Occlusion Hospitalization 5/28/2008 Female 86 lb 7/14/2008 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 9/21/2006 Male 123 lb 7/29/2008 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 7/31/2008 Male 139 lb 8/12/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/5/2007 46 Male 143 lb 8/25/2008 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 7/31/2008 Male 139 lb 9/16/2008 Physician Japan
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 4/3/2008 Female 9/17/2008 Physician Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 8/18/2008 76 Male 9/18/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/5/2007 Male 143 lb 9/16/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/13/2008 62 Male 139 lb 10/31/2008 Physician Japan
Primary
Concomitant
Cardio-respiratory Arrest Death 8/18/2008 76 Male 11/3/2008 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 9/21/2006 Male 123 lb 11/24/2008 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 6/13/2008 62 Male 139 lb 12/29/2008 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 10/27/2008 68 Male 171 lb 2/10/2009 Physician Japan
Primary
Concomitant
Muscle Spasms Other Serious 2/20/2008 Female 99 lb 2/11/2009 Physician Japan
Primary
Concomitant
Infection Other Serious 4/11/2007 Male 165 lb 3/4/2009 Physician Japan
Primary
Secondary
Concomitant
Sequestrectomy Hospitalization 2/1/2009 Male 150 lb 6/26/2009 Physician Japan
Primary
Concomitant
Feeling Abnormal Other Serious 77 Female 7/31/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 77 Female 8/7/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/1/2006 53 Female 112 lb 12/22/2009 Japan
Primary
Interacting
Stevens-johnson Syndrome Hospitalization 10/1/2006 53 Female 112 lb 1/4/2010 Japan
Primary
Interacting
Interstitial Lung Disease Life Threatening 11/25/2008 70 Female 73 lb 3/24/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 32 Female 5/27/2010 Physician Japan
Primary
Concomitant
Cardio-respiratory Arrest Death Female 6/9/2010 Physician Japan
Primary
Concomitant
Herpes Zoster Oticus Hospitalization 4/13/2010 67 Female 93 lb 7/15/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Life Threatening 3/1/2010 70 Male 123 lb 7/19/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/27/2010 70 Female 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Female Life Threatening 4/26/2010 71 Female 165 lb 8/10/2010 Other Health Professional Japan
Primary
Concomitant
Lower Respiratory Tract Infection Life Threatening 3/1/2010 70 Male 123 lb 8/16/2010 Physician Japan
Primary
Concomitant
Renal Disorder Hospitalization 4/27/2010 57 Male 137 lb 8/25/2010 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Female Life Threatening 4/26/2010 71 Female 165 lb 9/1/2010 Other Health Professional Japan
Primary
Concomitant
Tinnitus Other Serious 9/14/2010 9 Female 9/24/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 9/13/2010 62 Female 9/29/2010 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 9/1/2010 64 Male 9/30/2010 Physician Japan
Primary
Concomitant
Tinnitus 9/14/2010 9 Female 66 lb 10/1/2010 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2010 66 Male 143 lb 10/11/2010 Physician Japan
Primary
Concomitant
Liver Disorder Life Threatening 9/13/2010 62 Female 10/21/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/28/2010 12 Male 106 lb 10/25/2010 Pharmacist Japan
Primary
Concomitant
Paralysis Hospitalization 11/13/2010 39 Male 11/22/2010 Pharmacist Japan
Primary
Concomitant
Pneumonia Other Serious 4/30/2009 83 Female 97 lb 11/22/2010 Physician Japan
Primary
Concomitant
Paralysis Hospitalization 11/13/2010 39 Male 11/29/2010 Pharmacist Japan
Primary
Concomitant
Liver Disorder Life Threatening 9/14/2010 62 Female 12/1/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/14/2010 62 12/10/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Life Threatening 9/14/2010 62 12/21/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/30/2009 83 Female 97 lb 12/29/2010 Physician Japan
Primary
Concomitant
Paronychia Hospitalization 7/7/2010 1/5/2011 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Death 10/23/2009 64 Male 99 lb 1/20/2011 Physician Japan
Primary
Concomitant
Pneumonia Pneumococcal Hospitalization 2/22/2011 64 Female 84 lb 3/22/2011 Physician Japan
Primary
Secondary
Concomitant
Lower Limb Fracture Hospitalization Female 5/3/2011 Other Health Professional Germany
Primary
Concomitant
Restlessness Hospitalization 4/13/2011 56 Female 91 lb 5/12/2011 Pharmacist Japan
Primary
Concomitant
Lower Limb Fracture Hospitalization 7/29/2009 75 Female 5/19/2011 Other Health Professional Germany
Primary
Concomitant
Hepatitis Fulminant Life Threatening 4/6/2011 72 Male 123 lb 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Death 3/30/2011 73 Male 120 lb 6/1/2011 Physician Japan
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 5/20/2011 80 Male 6/3/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Muscular Weakness 3/11/2011 80 Male 6/8/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Hypoacusis Other Serious 3/1/2011 77 Female 6/13/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Death 3/30/2011 73 Male 120 lb 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Other Serious 3/31/2011 68 Male 88 lb 6/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Disorder Death 2/25/2011 73 Female 90 lb 6/17/2011 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 5/23/2011 71 Male 6/23/2011 Pharmacist Japan
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization Male 118 lb 6/24/2011 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 6/15/2011 39 Female 6/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Urea Abnormal Hospitalization 5/23/2011 71 Male 7/7/2011 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 6/15/2011 39 Female 7/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 5/23/2011 71 Male 143 lb 7/14/2011 Physician Japan
Primary
Secondary
Concomitant
Deafness Other Serious 3/1/2011 77 Female 77 lb 7/18/2011 Physician Japan
Primary
Concomitant
Pulmonary Haemorrhage Other Serious 1/1/2011 68 Male 88 lb 7/21/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/21/2011 56 Female 7/21/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Death 6/19/2011 71 Male 123 lb 7/22/2011 Other Health Professional Japan
Primary
Concomitant
Oedema Death 7/7/2010 76 Male 170 lb 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Deafness Other Serious 3/1/2011 77 Female 77 lb 7/27/2011 Physician Japan
Primary
Concomitant
Incorrect Dose Administered Other Serious 4/13/2011 56 Female 91 lb 7/29/2011 Pharmacist Japan
Primary
Concomitant
Liver Disorder Death 2/25/2011 73 Female 90 lb 8/1/2011 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 5/13/2011 64 Male 8/8/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/29/2011 67 Female 8/17/2011 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 6/15/2011 39 Female 111 lb 8/17/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/11/2011 61 Male 117 lb 8/18/2011 Physician Japan
Primary
Concomitant
Asthma Hospitalization 7/1/2011 8/23/2011 Physician Japan
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization Male 118 lb 8/29/2011 Physician Japan
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/11/2011 61 Male 117 lb 8/31/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 7/29/2011 67 Female 8/31/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/29/2011 67 Female 9/6/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/11/2011 61 Male 117 lb 9/8/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 7/29/2011 67 Female 106 lb 9/13/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/11/2011 61 Male 117 lb 9/22/2011 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/16/2009 63 Male 119 lb 9/28/2011 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 5/13/2011 64 Male 10/21/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Dry Skin Death 10/1/2010 62 Female 79 lb 10/27/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 11/3/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/29/2011 67 Female 106 lb 11/11/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data