Clarithromycin combined with Digoxin

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Melaena Hospitalization 11/8/2005 65 Male 1/27/2006 Pharmacist United States
Primary
Concomitant
Petechiae Hospitalization 1/16/2006 93 Female 88 lb 2/14/2006 Consumer France
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 1/2/2006 93 Female 88 lb 2/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/14/2005 73 Female 3/2/2006 Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2/4/2006 66 Female 126 lb 4/6/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 56 Female 4/18/2006 Physician Pakistan
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 7/10/2006 72 Female 8/23/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 7/10/2006 72 Female 8/21/2006 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Life Threatening 7/10/2006 72 Female 8/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 7/10/2006 72 Female 8/31/2006 United Kingdom
Primary
Secondary
Concomitant
Hepatorenal Failure Death 8/12/2006 4 Male 9/1/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Hepatorenal Failure Death 8/12/2006 4 Male 9/1/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Pneumonia Hospitalization 3/2/2006 Female 9/18/2006 Physician United Kingdom
Primary
Concomitant
Hepatorenal Failure Death 8/18/2006 4 Male 9/13/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Sepsis Death 9/3/2006 45 Male 99 lb 10/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 9/3/2006 83 Male 99 lb 10/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 9/3/2006 83 Male 99 lb 10/12/2006 United Kingdom
Primary
Concomitant
Reflux Oesophagitis Other Serious 4/5/2006 84 Female 10/20/2006 Physician Japan
Primary
Concomitant
Interacting
Oesophageal Ulcer Hospitalization 80 Male 10/26/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 80 Male 11/3/2006 United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/3/2006 45 Male 992 lb 11/3/2006 United Kingdom
Primary
Concomitant
Oesophageal Ulcer Hospitalization 80 Male 11/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/3/2006 45 Male 99 lb 11/9/2006 United Kingdom
Primary
Concomitant
Oesophageal Ulcer Hospitalization 80 Male 11/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Other Serious 80 Male 11/9/2006 United Kingdom
Primary
Secondary
Concomitant
Pigmentation Disorder Hospitalization 7/18/2006 77 Female 103 lb 12/4/2006 Physician Japan
Primary
Concomitant
Pigmentation Disorder Hospitalization 7/18/2006 77 Female 103 lb 12/15/2006 Physician Japan
Primary
Concomitant
Reflux Oesophagitis Other Serious 4/5/2006 84 Female 2/7/2007 Physician Japan
Primary
Concomitant
Interacting
Sepsis Hospitalization 9/3/2006 83 Male 99 lb 5/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Faeces Discoloured Hospitalization 4/22/2007 90 Male 5/24/2007 United Kingdom
Primary
Concomitant
General Physical Health Deterioration Hospitalization 78 Male 8/27/2007 Physician Belgium
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 66 Male 9/5/2007 Japan
Primary
Secondary
Hepatic Enzyme Increased Other Serious 9/19/2006 67 Male 10/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Torsade De Pointes Hospitalization 2/8/2008 79 Female 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 3/6/2008 78 Female 101 lb 4/14/2008 Physician Japan
Primary
Concomitant
Vena Cava Injury Death 2/8/2008 Female 180 lb 6/10/2008 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2008 75 Female 6/26/2008 Other Health Professional Canada
Primary
Concomitant
Pneumonia Hospitalization 3/11/2006 7/3/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Life Threatening 86 Female 7/11/2008 United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 7/10/2006 72 Female 8/24/2008 United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/3/2006 45 Male 8/26/2008 United Kingdom
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/25/2008
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 10/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 8/13/2008 78 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 10/3/2007 Male 101 lb 10/14/2008 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/2/2008 85 Female 10/16/2008 France
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 4/24/2008 66 Male 101 lb 12/31/2008 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 12/10/2008 87 Female 1/12/2009 Physician United Kingdom
Primary
Concomitant
Pancytopenia Other Serious 12/10/2008 87 Female 1/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hepatitis Acute Other Serious Male 1/15/2009 Physician Germany
Primary
Secondary
Hepatitis Acute Other Serious Male 1/12/2009 Physician Germany
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious Male 1/16/2009 Other Health Professional Germany
Primary
Secondary
Bone Marrow Failure Other Serious 12/10/2008 87 Female 1/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hepatitis Acute Other Serious Male 1/16/2009 Germany
Primary
Secondary
Bone Marrow Failure Other Serious 12/10/2008 87 Female 1/21/2009 United Kingdom
Primary
Concomitant
Skin Laceration Hospitalization 71 Male 2/27/2009 Physician Germany
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 3/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 71 Male 3/18/2009 Physician Germany
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 3/30/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 3/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 3/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/2/2009 Other Health Professional
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/7/2009
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/3/2009
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 3/10/2009 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/10/2009 Pharmacist Japan
Primary
Secondary
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/15/2009 Pharmacist Japan
Primary
Secondary
Hepatic Function Abnormal Other Serious 12/29/2008 66 Female 88 lb 4/20/2009 Pharmacist Japan
Primary
Concomitant
Tonic Convulsion Hospitalization 3/10/2009 82 Male 4/21/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 82 Male 4/16/2009 United Kingdom
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/22/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/27/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/29/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 12/29/2008 66 Female 88 lb 5/6/2009 Pharmacist Japan
Primary
Concomitant
Tonic Convulsion Hospitalization 3/10/2009 82 Male 5/6/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 5/13/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Ulcer Other Serious 63 Female 5/11/2009 United States
Primary
Concomitant
Liver Disorder Hospitalization 12/29/2008 66 Female 88 lb 6/23/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 67 Male 6/17/2009 United States
Primary
Concomitant
Tic Other Serious 4/3/2008 61 Male 201 lb 6/19/2009 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 1/1/2008 75 Female 6/30/2009 Other Health Professional Canada
Primary
Concomitant
Pyrexia Hospitalization 1/1/2008 75 Female 6/30/2009 Other Health Professional Canada
Primary
Concomitant
Sinusitis Other Serious 61 Female 7/2/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 73 Female 7/14/2009 United States
Primary
Concomitant
Xanthopsia Hospitalization 4/1/2009 78 Female 7/16/2009 Physician Switzerland
Primary
Secondary
Tonic Convulsion Hospitalization 3/8/2009 82 Male 7/24/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/21/2008 66 Male 179 lb 7/21/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 8/5/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 8/13/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 53 Female 8/27/2009 United States
Primary
Concomitant
Vomiting Hospitalization 70 Female 8/28/2009 United States
Primary
Concomitant
Respiratory Distress Other Serious Male 154 lb 9/4/2009 Consumer Australia
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 9/2/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 9/2/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 9/2/2009 Lawyer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 70 Female 9/3/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 53 Female 9/11/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 53 Female 9/29/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 60 Female 9/29/2009 United States
Primary
Concomitant
Pneumonia Staphylococcal Death 5/18/2009 77 Male 9/29/2009 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 10/17/2009 United States
Primary
Concomitant
Thyroid Cyst Hospitalization 11/2/2007 78 Female 10/21/2009 United States
Primary
Concomitant
Vasodilatation Male 10/26/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 5/1/2009 97 Male 11/6/2009 Consumer Australia
Primary
Secondary
Concomitant
Interacting
Vasodilatation 43 Male 11/4/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 11/4/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 11/17/2009 Lawyer United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 51 Male 12/1/2009 Lawyer United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 51 Male 12/10/2009 United States
Primary
Concomitant
Vomiting Hospitalization 79 Male 12/10/2009 United States
Primary
Concomitant
Thyroid Cyst Hospitalization 11/2/2007 78 Female 12/11/2009 United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 10/8/2009 Male 12/18/2009 Physician United Kingdom
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 68 Female 12/22/2009 Pharmacist Australia
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 51 Male 1/13/2010 United States
Primary
Concomitant
Vomiting Hospitalization 60 Female 1/22/2010 United States
Primary
Concomitant
Vomiting Hospitalization 79 Male 1/21/2010 United States
Primary
Concomitant
Snoring Hospitalization 51 Male 1/27/2010 United States
Primary
Concomitant
Pallor Hospitalization 75 Male 1/22/2010 Lawyer United States
Primary
Concomitant
Systemic Lupus Erythematosus Disability 63 Female 2/5/2010 United States
Primary
Concomitant
Vision Blurred Hospitalization 43 Male 2/17/2010 United States
Primary
Concomitant
Laboratory Test Abnormal Hospitalization 8/1/2008 68 Female 3/2/2010 Consumer Australia
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/1/2008 68 Female 3/10/2010 Pharmacist Australia
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/1/2008 60 Female 3/19/2010 Consumer Australia
Primary
Secondary
Concomitant
Tachycardia Other Serious 6/1/2000 60 Female 3/29/2010
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 3/25/2010 United States
Primary
Concomitant
Tachycardia Other Serious 60 Female 3/25/2010 Australia
Primary
Secondary
Concomitant
Tachycardia Other Serious 8/1/2008 68 Female 4/5/2010 Pharmacist Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 4/22/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/1/2008 68 Female 5/13/2010 Consumer Australia
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 71 Male 5/14/2010 Pharmacist Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Interacting
Tachycardia Other Serious 60 Female 6/4/2010 Australia
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 40 Male 238 lb 6/9/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 51 Male 8/4/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 52 Female 8/18/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/4/2010 75 Female 154 lb 10/15/2010 Physician Greece
Primary
Secondary
Concomitant
Treatment Failure Death 5/18/2009 77 Male 139 lb 11/2/2010 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 80 Female 12/16/2010 Consumer Australia
Primary
Secondary
Concomitant
Muscle Haemorrhage Other Serious 12/30/2010 74 Female 134 lb 2/4/2011 Physician United Kingdom
Primary
Concomitant
Interacting
Haemoglobin Decreased Hospitalization 12/30/2010 74 Female 134 lb 2/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Potentiating Drug Interaction Hospitalization 12/30/2010 74 Female 134 lb 2/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 74 Female 2/11/2011 United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 1/1/2011 79 Female 3/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Confusional State Disability 1/1/2011 79 Female 132 lb 3/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/22/2011 79 Female 2/21/2011 Other Health Professional
Primary
Concomitant
Radial Pulse Decreased Death 70 Female 119 lb 3/11/2011 Other Health Professional Brazil
Primary
Secondary
Concomitant