Cisplatin combined with Trastuzumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
General Physical Health Deterioration Death 3/17/2006 50 Male 3/31/2006 Physician Russian Federation
Primary
Secondary
Gout Hospitalization 1/8/2007 71 Male 143 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 100 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 100 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/8/2007 71 Male 143 lb 3/2/2007 Physician Japan
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 11/16/2006 69 Male 170 lb 3/5/2007 Physician Denmark
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/8/2007 71 Male 143 lb 3/6/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/8/2007 71 Male 143 lb 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/28/2007 Male 4/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/28/2007 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/28/2007 Male 5/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/8/2007 71 Male 143 lb 5/22/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Abnormal Hospitalization 5/30/2007 Male 6/19/2007 Physician Spain
Primary
Secondary
Concomitant
Cardiovascular Disorder Hospitalization 5/23/2007 75 Female 157 lb 6/27/2007 Physician Germany
Primary
Secondary
Cardiovascular Disorder Hospitalization 5/23/2007 Female 157 lb 6/28/2007 Physician United Kingdom
Primary
Secondary
Platelet Count Abnormal Hospitalization 5/30/2007 Male 8/2/2007 Physician Spain
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 11/16/2006 69 Male 170 lb 9/19/2007 Physician Denmark
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 11/16/2006 69 Male 170 lb 10/1/2007 Physician Denmark
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 10/21/2007 Male 97 lb 11/20/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/21/2007 Male 97 lb 11/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 10/21/2007 Female 154 lb 12/11/2007 Physician United Kingdom
Primary
Concomitant
Ejection Fraction Decreased Hospitalization 12/7/2007 56 Male 120 lb 1/31/2008 Physician Korea, Republic Of
Primary
Secondary
Gastritis Hospitalization 11/29/2007 Female 121 lb 2/1/2008 Consumer United Kingdom
Primary
Secondary
Respiratory Distress Hospitalization 1/6/2008 65 Male 111 lb 2/8/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Gastritis Hospitalization 11/29/2007 26 Female 121 lb 2/8/2008 Physician Mexico
Primary
Secondary
Gastritis Hospitalization 11/29/2007 Female 121 lb 2/14/2008 Consumer United Kingdom
Primary
Secondary
Gastritis Hospitalization 11/29/2007 26 Female 121 lb 2/15/2008 Physician Mexico
Primary
Secondary
Ejection Fraction Decreased Hospitalization 12/7/2007 56 Male 120 lb 2/18/2008 Physician Korea, Republic Of
Primary
Secondary
Cardiac Failure Hospitalization 1/29/2008 69 Male 2/20/2008 Physician Japan
Primary
Secondary
Pyrexia Hospitalization 2/14/2008 64 Male 126 lb 3/4/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 69 Male 104 lb 3/11/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 3/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 69 Male 104 lb 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 3/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/14/2008 64 Male 126 lb 3/19/2008 Physician Japan
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 1/1/2008 48 Female 3/20/2008 United States
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 4/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 4/7/2008 Male 4/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tetany Hospitalization 4/7/2008 Male 102 lb 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/7/2008 Male 102 lb 4/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/29/2008 Male 104 lb 5/1/2008 Physician Japan
Primary
Secondary
Concomitant
Death Death 4/7/2007 Male 91 lb 5/1/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 2/4/2008 Male 104 lb 5/6/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 4/7/2007 5/7/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 4/7/2007 Male 91 lb 5/30/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Death Death 4/7/2007 6/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 4/7/2007 Male 91 lb 6/4/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Death Death 4/7/2007 Male 91 lb 6/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/14/2008 Male 126 lb 6/10/2008 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 6/12/2008 Physician Japan
Primary
Secondary
Concomitant
Death Death 4/7/2007 Male 91 lb 6/16/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 6/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 3/13/2008 Male 160 lb 6/23/2008 Physician Russian Federation
Primary
Secondary
Concomitant
Death Death 4/7/2007 Male 91 lb 6/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Lethargy Hospitalization 3/20/2008 Male 7/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 7/21/2008 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 7/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiovascular Disorder Hospitalization 5/23/2007 Female 157 lb 8/12/2008 Physician Germany
Primary
Secondary
Cardiovascular Disorder Hospitalization 5/23/2007 Female 157 lb 8/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 9/19/2008 Male 10/8/2008 Physician United Kingdom
Primary
Secondary
Death Death 10/2/2008 Male 115 lb 10/15/2008 Physician Korea, Republic Of
Primary
Secondary
Death Death 10/2/2008 Male 115 lb 10/17/2008 Consumer United Kingdom
Primary
Secondary
Death Death 10/17/2008 Male 99 lb 10/27/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Death Male 10/27/2008 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 9/12/2008 Male 10/30/2008 Physician United Kingdom
Primary
Concomitant
Death Death 10/17/2008 Male 10/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Death 11/22/2008 Male 12/4/2008 Physician United Kingdom
Primary
Secondary
Orthostatic Hypotension Hospitalization 5/23/2007 Female 157 lb 1/27/2009 Physician Germany
Primary
Secondary
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 2/19/2009 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 2/25/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Death 11/22/2008 Male 3/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 10/2/2008 Male 115 lb 4/14/2009 Physician Korea, Republic Of
Primary
Secondary
Pyrexia Hospitalization 3/18/2009 Male 4/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 10/2/2008 Male 115 lb 4/20/2009 Consumer United Kingdom
Primary
Secondary
Death Death 4/1/2009 Male 185 lb 4/24/2009 Physician Russian Federation
Primary
Secondary
Platelet Count Abnormal Hospitalization 5/30/2007 Male 4/28/2009 Physician Spain
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/28/2007 Male 4/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 4/1/2009 Male 185 lb 4/28/2009 Consumer United Kingdom
Primary
Secondary
Metastases To Central Nervous System Other Serious 7/1/2002 38 Female 5/8/2009 Other Health Professional Italy
Primary
Secondary
Death Death 4/1/2009 Male 185 lb 5/27/2009 Consumer United Kingdom
Primary
Secondary
Endocarditis Bacterial Hospitalization 11/16/2006 Male 6/2/2009 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 3/18/2009 Male 6/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Endocarditis Bacterial Hospitalization 11/16/2006 Male 6/8/2009 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 3/18/2009 Male 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 56 Female 7/8/2009 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 6/16/2009 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 3/18/2009 Male 7/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/1/2006 56 Female 7/30/2009 Other Health Professional Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 4/1/2008 42 Female 12/28/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Vomiting Other Serious 4/30/2002 47 Female 6/10/2010 Physician United States
Primary
Secondary
Concomitant
Disease Recurrence Death 4/21/2009 37 Female 172 lb 6/23/2010 Other Health Professional Germany
Primary
Concomitant
Transaminases Increased Hospitalization 10/7/2010 60 Male 205 lb 10/19/2010 Physician Germany
Primary
Secondary
Renal Failure Acute Hospitalization 10/7/2010 60 Male 205 lb 11/4/2010 Physician Germany
Primary
Secondary
Deep Vein Thrombosis Life Threatening 9/22/2007 44 Female 1/3/2011 Physician Italy
Primary
Secondary
Concomitant
Death Death 1/24/2011 66 Male 165 lb 2/4/2011 Physician Germany
Primary
Secondary
Death Death 1/24/2011 66 Male 165 lb 3/9/2011 Physician Germany
Primary
Secondary
Bone Marrow Toxicity Other Serious 3/18/2011 Physician Italy
Primary
Secondary
Dehydration Hospitalization 2/4/2011 71 Male 162 lb 4/11/2011 Physician Germany
Primary
Secondary
Neoplasm Progression Death 6/21/2011 55 Male 7/5/2011 Physician Germany
Primary
Secondary
Abdominal Pain Hospitalization 2/4/2011 71 Male 162 lb 7/14/2011 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 10/10/2001 11 Male 11/29/2011 Physician United States
Primary
Secondary
Pyrexia Hospitalization 10/1/2001 11 Male 12/22/2011 Consumer United States
Primary
Secondary
Infection Life Threatening 12/8/2001 12 Male 12/23/2011 Physician United States
Primary
Secondary
Blood Pressure Increased Other Serious 7/11/2011 60 Male 216 lb 2/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 10/10/2001 11 Male 2/17/2012 Physician United States
Primary
Secondary
Hyponatraemia Other Serious 1/4/2004 21 Female 2/28/2012 Physician United States
Primary
Secondary
Hypokalaemia Other Serious 2/20/2004 13 2/29/2012 Physician United States
Primary
Secondary
Concomitant
Hypertension Other Serious Female 6/2/2012 Other Health Professional Italy
Primary
Secondary
Diarrhoea Other Serious Female 6/2/2012 Other Health Professional Italy
Primary
Secondary
Sepsis Other Serious Female 6/2/2012 Other Health Professional Italy
Primary
Secondary
Asthenia Other Serious Female 6/2/2012 Other Health Professional Italy
Primary
Secondary
Sepsis Other Serious Female 6/2/2012 Other Health Professional Italy
Primary
Secondary
Deep Vein Thrombosis Other Serious Female 6/2/2012 Other Health Professional Italy
Primary
Secondary
Hyperglycaemia Hospitalization 7/17/2012 Male 8/17/2012 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/29/2012 68 Male 121 lb 3/22/2013 Physician Kr
Primary
Secondary
Concomitant
Stomatitis Other Serious 3/4/2012 61 Male 185 lb 3/18/2013 Physician De
Primary
Secondary
Mucosal Inflammation Other Serious 3/25/2012 76 Male 164 lb 3/18/2013 Physician Es
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 6/29/2012 69 Female 106 lb 2/27/2013 Physician Kr
Primary
Secondary
Concomitant
Neutropenia Other Serious 9/4/2012 Physician Us
Primary
Secondary
Concomitant
Renal Impairment Other Serious 78 Male 9/14/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 10/23/2012 68 Male 152 lb 10/25/2012 Physician Ve
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/4/2012 69 Male 137 lb 3/9/2013 Physician Kr
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/29/2012 Male 187 lb 11/8/2012 Physician De
Primary
Concomitant
Disease Progression Other Serious Male 11/20/2012 Physician Ca
Primary
Secondary
Neutropenia Hospitalization 10/28/2009 68 Male 117 lb 11/27/2012 Physician Jp
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/7/2012 Male 161 lb 2/26/2013 Physician De
Primary
Secondary
Disease Progression Other Serious Male 12/10/2012 Country Not Specified
Primary
Concomitant
Disease Progression Other Serious Male 12/12/2012 Country Not Specified
Primary
Secondary
Rectal Haemorrhage Death 10/1/2010 62 Female 90 lb 2/8/2013 Physician De
Primary
Concomitant
Toxicity To Various Agents Other Serious Male 12/26/2012 Physician Ca
Primary
Secondary
Mucosal Inflammation Other Serious Male 12/26/2012 Physician Ca
Primary
Secondary
Death Death Female 12/26/2012 Physician Ca
Primary
Secondary
Tremor Other Serious NotSpecified 1/2/2013 Other Health Professional It
Primary
Concomitant
Nervous System Disorder Hospitalization 3/28/2002 60 Female 1/24/2013 Physician Ca
Primary
Secondary
Concomitant
Liver Disorder Other Serious 7/2012 Female 176 lb 2/18/2013 Physician Dk
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/2012 53 Female 106 lb 5/13/2013 Physician Be
Primary
Secondary
Concomitant
Liver Disorder Other Serious Female 176 lb 2/25/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Liver Disorder Other Serious 7/2012 Female 176 lb 3/1/2013 Physician Dk
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 176 lb 2/26/2013 Physician Dk
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/2012 64 Female 98 lb 3/6/2013 Physician At
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 44 Female 3/18/2013 Other Health Professional Country Not Specified
Primary
Secondary
Sepsis Other Serious NotSpecified 3/19/2013 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Vomiting Other Serious 10/29/2012 Physician Us
Primary
Secondary
Concomitant
Troponin Other Serious NotSpecified 3/22/2013 Physician Us
Primary
Secondary
Off Label Use Other Serious NotSpecified 3/22/2013 Other Health Professional Us
Primary
Secondary
Acute Myocardial Infarction Life Threatening 4/13/2013 50 Male 222 lb 4/18/2013 Physician De
Primary
Secondary
Concomitant
Vomiting Other Serious 5/2012 58 Male 135 lb 4/27/2013 Consumer Ca
Primary
Secondary
Concomitant
Obstruction Gastric Hospitalization 5/19/2013 69 Male 97 lb 6/12/2013 Physician Cn
Primary
Secondary
Concomitant

Drug Data