Cisplatin combined with Sorafenib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Dyspnoea Life Threatening 3/28/2007 62 Female 137 lb 4/11/2007 Physician Belgium
Primary
Secondary
Concomitant
Sepsis Death 6/22/2007 66 187 lb 6/28/2007 Physician United States
Primary
Secondary
Sepsis Hospitalization 6/22/2007 Female 186 lb 6/25/2007 Consumer United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/8/2007 63 Male 141 lb 7/3/2007 Physician United States
Primary
Secondary
Vomiting Other Serious 5/11/2007 49 Female 148 lb 7/12/2007 Physician Germany
Primary
Concomitant
Vomiting Other Serious 5/11/2007 49 Female 148 lb 7/18/2007 Physician Germany
Primary
Concomitant
Thrombocytopenia Life Threatening 7/16/2007 76 Male 174 lb 7/27/2007 Physician Germany
Primary
Secondary
Concomitant
Sleep Disorder Other Serious Male 8/8/2007 Consumer Germany
Primary
Concomitant
Arrhythmia Hospitalization 8/3/2007 65 Male 148 lb 8/16/2007 Physician Germany
Primary
Secondary
Cerebrovascular Accident Disability 8/7/2007 40 Male 159 lb 8/16/2007 Physician Spain
Primary
Secondary
Cardiac Tamponade Hospitalization 8/29/2007 54 Male 205 lb 9/12/2007 Physician Belgium
Primary
Secondary
Cardiac Tamponade Death 8/29/2007 54 Male 205 lb 9/13/2007 Physician Belgium
Primary
Secondary
Thrombocytopenia Life Threatening 8/21/2007 65 Male 9/13/2007 Physician Netherlands
Primary
Secondary
Concomitant
Cardiac Tamponade Death 8/29/2007 54 Male 205 lb 9/14/2007 Physician Belgium
Primary
Secondary
Sepsis Hospitalization Male 9/18/2007 Physician Germany
Primary
Secondary
Concomitant
Cardiac Tamponade Death 8/29/2007 54 Male 205 lb 9/21/2007 Physician Belgium
Primary
Secondary
Cerebral Ischaemia Other Serious 8/7/2007 40 Male 159 lb 9/21/2007 Physician Spain
Primary
Secondary
Concomitant
Cerebral Ischaemia Other Serious 8/7/2007 40 Male 159 lb 9/24/2007 Physician Spain
Primary
Secondary
Concomitant
Leukopenia Other Serious 9/7/2007 59 Male 130 lb 9/27/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/7/2007 68 Male 143 lb 10/9/2007 Physician Germany
Primary
Secondary
Concomitant
Sepsis Death 6/22/2007 66 Female 187 lb 10/18/2007 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/23/2007 63 Male 194 lb 10/18/2007 Physician Italy
Primary
Secondary
Concomitant
Sleep Disorder Other Serious Male 10/19/2007 Consumer Germany
Primary
Concomitant
Thrombocytopenia Life Threatening 7/16/2007 76 Male 174 lb 10/19/2007 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 8/13/2007 45 Male 10/19/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/7/2007 68 Male 143 lb 10/19/2007 Physician Germany
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/23/2007 63 Male 194 lb 10/22/2007 Physician Italy
Primary
Secondary
Concomitant
Leukopenia Life Threatening 9/7/2007 59 Male 130 lb 10/24/2007 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/22/2007 69 Male 179 lb 11/8/2007 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 10/30/2007 62 Male 11/14/2007 Physician France
Primary
Secondary
Concomitant
Leukopenia Life Threatening 9/7/2007 59 Male 130 lb 11/15/2007 Physician Germany
Primary
Secondary
Concomitant
Electrolyte Imbalance Hospitalization 10/17/2007 65 Male 196 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 10/30/2007 62 Male 11/26/2007 Physician France
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 10/30/2007 62 Male 12/14/2007 Physician France
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 12/3/2007 Male 1/3/2008 Other Health Professional Italy
Primary
Secondary
Hypophosphataemia Other Serious 8/23/2007 63 Male 194 lb 1/7/2008 Physician Italy
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/3/2007 65 Male 148 lb 1/7/2008 Physician Germany
Primary
Secondary
General Physical Health Deterioration Hospitalization 12/17/2007 69 Male 1/8/2008 Physician France
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 12/1/2007 37 Male 154 lb 1/9/2008 Physician China
Primary
Secondary
Haemoptysis Other Serious 11/29/2007 69 Male 115 lb 1/25/2008 Physician France
Primary
Secondary
Concomitant
Sepsis Death 6/22/2007 66 Female 187 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 12/1/2007 37 Male 154 lb 2/1/2008 Physician China
Primary
Secondary
Skin Toxicity Other Serious 12/3/2007 Male 2/5/2008 Other Health Professional Italy
Primary
Secondary
Renal Infarct Hospitalization 10/28/2007 61 Female 172 lb 2/12/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 12/1/2007 37 Male 154 lb 3/6/2008 Physician China
Primary
Secondary
Cerebrovascular Accident Other Serious 2/21/2008 59 Male 196 lb 3/6/2008 Physician Belgium
Primary
Secondary
Cerebrovascular Accident Other Serious 2/21/2008 59 Male 196 lb 3/11/2008 Physician Belgium
Primary
Secondary
Concomitant
Septic Shock Death 1/29/2008 59 Male 150 lb 3/13/2008 Physician Italy
Primary
Secondary
Lung Abscess Hospitalization 3/14/2008 63 Male 185 lb 3/21/2008 Physician China
Primary
Secondary
Electrolyte Imbalance Hospitalization 10/17/2007 65 Male 196 lb 3/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 9/1/2007 53 Male 161 lb 4/4/2008 Physician Germany
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 4/15/2008 56 Male 192 lb 4/24/2008 Physician Germany
Primary
Secondary
Concomitant
Arterial Thrombosis Hospitalization 3/28/2008 54 Male 143 lb 4/25/2008 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 4/12/2008 56 Male 192 lb 5/1/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 5/12/2008 Male 152 lb 5/23/2008 Physician Spain
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Hospitalization 5/13/2008 71 Male 150 lb 5/29/2008 Physician Spain
Primary
Secondary
Concomitant
Haemoptysis Other Serious 11/29/2007 69 Male 115 lb 5/30/2008 Physician France
Primary
Secondary
Concomitant
Oedema Hospitalization 1/1/2008 70 Male 121 lb 6/2/2008 Physician Italy
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/5/2008 70 Male 181 lb 7/16/2008 Mexico
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 5/12/2008 71 Male 152 lb 7/21/2008 Physician Spain
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/20/2007 70 Male 181 lb 7/31/2008 Mexico
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 10/30/2007 62 Male 8/1/2008 Physician France
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2008 United States
Primary
Secondary
Anal Fissure Hospitalization 7/28/2008 29 Female 190 lb 8/8/2008 Physician Canada
Primary
Secondary
Deep Vein Thrombosis Life Threatening 7/17/2008 68 Male 157 lb 8/8/2008 United Kingdom
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 7/28/2008 29 Female 190 lb 8/14/2008 Physician Canada
Primary
Secondary
Proctalgia Hospitalization 7/28/2008 29 Female 190 lb 8/27/2008 Physician Canada
Primary
Secondary
Deep Vein Thrombosis Life Threatening 7/17/2008 68 Male 157 lb 9/5/2008 United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/18/2007 70 Male 181 lb 9/18/2008 Mexico
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 11/29/2007 69 Male 115 lb 9/18/2008 Physician France
Primary
Secondary
Concomitant
Pulmonary Embolism Death 12/19/2007 37 Male 154 lb 9/22/2008 Physician China
Primary
Secondary
Aortic Dissection Life Threatening 9/14/2008 50 Male 190 lb 9/23/2008 Physician Italy
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 9/16/2008 67 Male 128 lb 9/30/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 9/22/2008 59 Female 218 lb 10/3/2008 United Kingdom
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Hospitalization 5/13/2008 71 Male 150 lb 10/7/2008 Physician Spain
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 9/22/2008 59 Female 218 lb 10/9/2008 United Kingdom
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Death 5/13/2008 71 Male 150 lb 10/30/2008 Physician Spain
Primary
Secondary
Concomitant
Tumour Associated Fever Other Serious 9/26/2008 66 Male 172 lb 11/4/2008 Physician Spain
Primary
Secondary
Concomitant
Tumour Associated Fever Other Serious 9/26/2008 66 Male 172 lb 11/12/2008 Physician Spain
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 3/14/2008 63 Male 185 lb 11/18/2008 Physician China
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 12/2/2008 71 Male 198 lb 12/5/2008 Physician Netherlands
Primary
Secondary
Wound Infection Hospitalization 10/28/2007 61 Female 176 lb 12/10/2008 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Hospitalization 10/28/2007 61 Female 176 lb 12/15/2008 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Hospitalization 10/28/2007 61 Female 176 lb 12/18/2008 Physician Germany
Primary
Secondary
Concomitant
Urogenital Fistula Other Serious 12/10/2008 61 Female 137 lb 12/22/2008 Physician Canada
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/22/2008 65 Male 1/8/2009 Physician Spain
Primary
Secondary
Venous Thrombosis Hospitalization 12/30/2008 66 Female 174 lb 1/8/2009 Physician Spain
Primary
Secondary
Aortic Dissection Life Threatening 9/14/2008 50 Male 181 lb 1/12/2009 Physician Italy
Primary
Secondary
Concomitant
Urogenital Fistula Hospitalization 12/10/2008 61 Female 137 lb 1/27/2009 Physician Canada
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 4/12/2008 56 Male 192 lb 1/27/2009 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 1/18/2009 61 Female 137 lb 1/29/2009 Physician Netherlands
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/22/2008 65 Male 143 lb 2/3/2009 Physician Spain
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 1/18/2009 61 Female 137 lb 2/3/2009 Physician Netherlands
Primary
Secondary
Concomitant
Urogenital Fistula Hospitalization 12/10/2008 61 Female 137 lb 2/6/2009 Physician Canada
Primary
Secondary
Concomitant
Small Cell Lung Cancer Stage Unspecified Other Serious 1/29/2009 64 Female 154 lb 2/9/2009 Other Health Professional United States
Primary
Secondary
Pulmonary Thrombosis Other Serious 2/4/2009 79 Male 168 lb 2/10/2009 Physician Greece
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 2/4/2009 76 Male 159 lb 2/13/2009 United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 2/21/2008 59 Male 196 lb 2/17/2009 Physician Belgium
Primary
Secondary
Concomitant
Pulmonary Embolism Death 11/26/2007 37 Male 154 lb 2/18/2009 Physician China
Primary
Secondary
Thrombocytopenia Other Serious 11/29/2008 53 Female 106 lb 2/20/2009 Physician Greece
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 2/4/2009 76 Male 159 lb 2/23/2009 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 2/4/2009 76 Male 159 lb 3/4/2009 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 12/2/2008 71 Male 198 lb 3/16/2009 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/5/2009 59 Male 165 lb 3/20/2009 Physician Germany
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 12/30/2008 66 Female 174 lb 3/24/2009 Physician Spain
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1/18/2009 61 Female 137 lb 3/25/2009 Physician Netherlands
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 9/26/2008 66 Male 172 lb 4/8/2009 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/29/2008 53 Female 106 lb 4/15/2009 Physician Greece
Primary
Secondary
Concomitant
Aortic Dissection Hospitalization 9/14/2008 50 Male 181 lb 4/16/2009 Physician Italy
Primary
Secondary
Concomitant
Peripheral Arterial Occlusive Disease Life Threatening 1/8/2009 72 Male 139 lb 4/20/2009 Physician Spain
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 3/31/2009 62 Female 4/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/26/2009 58 Male 157 lb 5/8/2009 Physician Spain
Primary
Secondary
Concomitant
Aortic Dissection Life Threatening 9/14/2008 50 Male 181 lb 5/11/2009 Physician Italy
Primary
Secondary
Concomitant
Wheezing Other Serious 3/31/2009 62 Female 5/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 12/2/2008 71 Male 198 lb 5/18/2009 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1/18/2009 61 Female 137 lb 5/18/2009 Physician Netherlands
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 5/19/2009 65 Male 123 lb 5/26/2009 Physician Belgium
Primary
Secondary
Concomitant
Wheezing Other Serious 3/26/2009 62 Female 5/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bartholin's Abscess Hospitalization 5/28/2009 50 Female 115 lb 6/4/2009 Physician China
Primary
Secondary
Concomitant
Convulsion Other Serious 5/28/2009 38 Male 207 lb 6/8/2009 Physician Brazil
Primary
Secondary
Wheezing Other Serious 3/26/2009 62 Female 6/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 5/28/2009 38 Male 207 lb 6/12/2009 Physician Brazil
Primary
Secondary
Fall Hospitalization 4/17/2009 69 Male 176 lb 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 4/17/2009 69 Male 176 lb 7/6/2009 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/19/2009 65 Male 123 lb 7/16/2009 Physician Belgium
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/19/2009 65 Male 123 lb 7/21/2009 Physician Belgium
Primary
Secondary
Concomitant
Wheezing Other Serious 3/26/2009 62 Female 7/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 4/17/2009 69 Male 176 lb 8/3/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/27/2009 58 Male 295 lb 8/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 5/28/2009 50 Female 115 lb 8/11/2009 Physician China
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/27/2009 58 Male 295 lb 8/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/27/2009 58 Male 295 lb 8/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/27/2009 58 Male 295 lb 9/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/27/2009 58 Male 295 lb 10/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/29/2008 53 Female 106 lb 11/6/2009 Physician Greece
Primary
Secondary
Concomitant
Lobar Pneumonia Hospitalization 2/6/2010 52 Female 123 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sputum Culture Positive Hospitalization 2/16/2010 52 Female 123 lb 2/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Hospitalization 2/16/2010 52 Female 123 lb 2/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 2/16/2010 52 Female 123 lb 2/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Hospitalization 2/16/2010 52 Female 123 lb 2/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/18/2007 70 Male 172 lb 3/11/2010 Mexico
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 2/18/2010 60 Male 204 lb 4/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Hospitalization 1/26/2010 60 Male 205 lb 4/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 9/22/2009 81 Male 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Infection Other Serious 2/25/2008 62 Male 165 lb 4/21/2010 Physician Germany
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 5/10/2008 69 Male 170 lb 4/22/2010 Physician Italy
Primary
Secondary
Concomitant
Thrombosis Other Serious 3/5/2010 67 Female 132 lb 4/22/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/27/2008 62 Male 181 lb 4/23/2010 Physician Italy
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/18/2007 70 Male 172 lb 4/30/2010 Mexico
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 11/29/2007 69 Male 115 lb 5/4/2010 Physician France
Primary
Secondary
Concomitant

Drug Data