Cisplatin combined with Pemetrexed

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Required Intervention 6/28/2005 61 Male 179 lb 10/21/2005 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 2/21/2005 71 Male 198 lb 4/17/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/28/2005 67 Male 162 lb 6/29/2006 Physician Italy
Primary
Secondary
Concomitant
Blood Magnesium Decreased Other Serious 49 8/31/2006 Consumer United Kingdom
Primary
Concomitant
Respiratory Disorder Death 2/6/2005 67 Male 155 lb 10/30/2006 Physician Argentina
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 47 Male 11/15/2006 Physician United States
Primary
Concomitant
Respiratory Disorder Death 2/6/2005 67 Male 155 lb 11/21/2006 Physician Argentina
Primary
Secondary
Concomitant
Subcutaneous Emphysema Hospitalization 7/18/2006 63 Male 209 lb 12/11/2006 Physician Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 47 Male 140 lb 12/11/2006 Physician United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 6/24/2006 66 Male 12/18/2006 Physician Finland
Primary
Concomitant
Septic Shock Hospitalization 7/6/2006 67 Male 121 lb 1/4/2007 Physician Belgium
Primary
Secondary
Concomitant
Aspergillosis Hospitalization 7/6/2006 67 Male 121 lb 1/17/2007 Physician Belgium
Primary
Secondary
Concomitant
Respiratory Disorder Death 2/6/2005 67 Male 155 lb 2/9/2007 Physician Argentina
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 2/8/2007 73 Female 97 lb 3/7/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2007 Male 3/15/2007 Physician
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/23/2007 65 Male 110 lb 3/21/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/27/2007 Male 4/4/2007 Physician Japan
Primary
Secondary
Concomitant
Pseudomembranous Colitis Hospitalization 2/23/2007 65 Male 110 lb 4/4/2007 Physician Japan
Primary
Secondary
Concomitant
Haemothorax Hospitalization 4/20/2007 58 Male 5/9/2007 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 5/6/2007 64 Male 5/10/2007 Physician Japan
Primary
Secondary
Atrial Fibrillation Other Serious 2/11/2007 71 Female 123 lb 5/14/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/26/2007 67 Male 150 lb 5/19/2007 Physician Japan
Primary
Secondary
Concomitant
Skin Hyperpigmentation Other Serious 46 Male 5/21/2007 Physician Mexico
Primary
Concomitant
Interstitial Lung Disease Other Serious 5/11/2007 78 Male 118 lb 5/23/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/8/2007 40 Female 218 lb 6/4/2007 Physician Denmark
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 5/6/2007 64 Male 140 lb 6/8/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/26/2007 67 Male 150 lb 6/12/2007 Physician Japan
Primary
Secondary
Concomitant
Pseudomonal Sepsis Hospitalization 5/1/2007 55 Male 99 lb 6/26/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/9/2007 75 Male 146 lb 7/1/2007 Physician Japan
Primary
Secondary
Concomitant
Drug Toxicity Death 64 Male 7/12/2007 Physician Spain
Primary
Concomitant
Laryngeal Dyspnoea Hospitalization 6/27/2007 52 Male 110 lb 7/11/2007 Physician Spain
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 7/5/2007 61 Male 121 lb 7/11/2007 Physician Japan
Primary
Secondary
Renal Failure Other Serious 64 Male 7/19/2007 Physician Spain
Primary
Concomitant
Interstitial Lung Disease Life Threatening 7/5/2007 61 Male 121 lb 7/18/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 4/1/2007 77 Female 7/18/2007 Physician Japan
Primary
Secondary
Renal Impairment Hospitalization 4/13/2007 75 Male 146 lb 7/20/2007 Physician Japan
Primary
Secondary
Concomitant
Pseudomonal Sepsis Hospitalization 6/27/2007 71 Female 7/23/2007 Physician Japan
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 7/12/2007 59 Male 7/25/2007 Physician Japan
Primary
Secondary
Blood Sodium Decreased Other Serious 4/16/2007 62 Male 102 lb 7/31/2007 Physician Japan
Primary
Secondary
Concomitant
Deafness Neurosensory Disability 5/10/2007 37 Male 170 lb 7/31/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Necrosis Other Serious 6/1/2007 54 Male 8/8/2007 Physician Japan
Primary
Secondary
Hyperkalaemia Hospitalization 6/12/2007 64 Male 142 lb 8/8/2007 Physician Japan
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Other Serious 2/7/2007 72 Male 125 lb 8/7/2007 Physician Japan
Primary
Secondary
Concomitant
Melaena Other Serious 7/1/2007 70 Male 140 lb 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Trismus Hospitalization 8/2/2007 49 Male 121 lb 8/16/2007 Physician Hungary
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/2/2007 68 Male 161 lb 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/9/2007 59 Female 125 lb 8/17/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Necrosis Other Serious 6/1/2007 54 Male 126 lb 8/23/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/17/2007 67 Male 141 lb 8/29/2007 Physician Germany
Primary
Secondary
Concomitant
Shock Other Serious 8/1/2007 74 Male 154 lb 8/30/2007 Physician Japan
Primary
Secondary
Pyrexia Hospitalization 7/15/2007 74 Male 123 lb 8/30/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Necrosis Other Serious 6/1/2007 54 Male 126 lb 8/28/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/16/2007 58 Male 141 lb 8/30/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/13/2007 75 Male 146 lb 8/29/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/7/2007 Male 134 lb 8/31/2007 Other Health Professional United States
Primary
Secondary
Ulcer Haemorrhage Other Serious 7/1/2007 70 Male 140 lb 9/4/2007 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 6/12/2007 64 Male 142 lb 9/4/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Necrosis Hospitalization 5/30/2007 54 Male 126 lb 9/5/2007 Physician Japan
Primary
Secondary
Concomitant
Gastric Perforation Death 8/1/2007 9/11/2007 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 7/12/2007 59 Male 122 lb 9/13/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 8/17/2007 67 Male 141 lb 9/6/2007 Physician Germany
Primary
Secondary
Concomitant
Nausea Disability 5/19/2007 61 Male 142 lb 9/12/2007 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Other Serious 7/1/2007 70 Male 140 lb 9/14/2007 Physician Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 7/20/2007 47 Female 110 lb 9/18/2007 Physician Canada
Primary
Secondary
Concomitant
Atrial Flutter Other Serious 8/19/2007 71 Male 121 lb 9/21/2007 Physician Japan
Primary
Secondary
Concomitant
Trismus Hospitalization 7/30/2007 49 Male 121 lb 9/25/2007 Physician Hungary
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2007 72 Female 86 lb 9/25/2007 Physician Japan
Primary
Secondary
Concomitant
Stress Cardiomyopathy Death 8/24/2007 Male 104 lb 10/2/2007 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 8/1/2007 Male 154 lb 10/2/2007 Physician Japan
Primary
Secondary
Concomitant
No Adverse Drug Reaction 61 Male 142 lb 9/25/2007 Physician Japan
Primary
Secondary
Concomitant
Parkinsonism Disability 8/15/2007 63 Male 140 lb 9/26/2007 Physician Japan
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/1/2007 45 Male 160 lb 9/28/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/15/2007 74 Male 123 lb 9/27/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/23/2007 Male 84 lb 10/1/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/19/2007 Female 132 lb 10/5/2007 Physician Japan
Primary
Secondary
Concomitant
Sputum Purulent Hospitalization 10/9/2007 Female 10/30/2007 Physician Belgium
Primary
Secondary
Concomitant
Lung Infiltration Life Threatening 10/10/2007 Female 107 lb 10/23/2007 Physician Germany
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 10/5/2007 Male 108 lb 10/28/2007 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 3/6/2007 Male 123 lb 10/18/2007 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Other Serious 5/1/2007 Male 10/30/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/3/2007 72 Female 86 lb 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
Laryngeal Oedema Hospitalization 10/24/2007 Male 175 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Stress Cardiomyopathy Hospitalization 8/24/2007 Male 104 lb 10/31/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/16/2007 Male 141 lb 11/2/2007 Physician Japan
Primary
Secondary
Concomitant
Blood Sodium Decreased Hospitalization 8/13/2007 Male 133 lb 11/13/2007 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Necrosis Death 10/31/2007 Male 143 lb 11/15/2007 Physician Hungary
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/9/2007 Male 103 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/16/2007 Male 157 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 4/26/2007 Male 160 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 4/16/2007 Male 102 lb 11/27/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 9/28/2007 Male 127 lb 11/27/2007 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 9/3/2007 Male 147 lb 11/27/2007 Physician Japan
Primary
Secondary
Concomitant
Pseudomonal Sepsis Hospitalization 6/20/2007 Female 132 lb 11/30/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/12/2007 Male 142 lb 11/30/2007 Physician Japan
Primary
Secondary
Concomitant
Sputum Retention Other Serious 11/19/2007 Male 119 lb 11/30/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/16/2007 Male 157 lb 11/30/2007 Physician Japan
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 5/16/2007 Male 146 lb 12/4/2007 Physician Japan
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 7/20/2007 Female 110 lb 11/28/2007 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/12/2007 Male 123 lb 11/26/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 9/28/2007 Male 127 lb 12/5/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/19/2007 Male 119 lb 12/5/2007 Physician Japan
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 10/5/2007 Male 108 lb 12/9/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/24/2007 Female 119 lb 12/9/2007 Physician Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 5/19/2007 Male 174 lb 12/9/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment 4/1/2007 77 Female 12/6/2007 Physician Japan
Primary
Secondary
Laryngeal Oedema Life Threatening 10/24/2007 Male 175 lb 12/4/2007 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 7/6/2007 Female 90 lb 12/10/2007 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 5/22/2007 Male 141 lb 12/6/2007 Physician Japan
Primary
Secondary
Concomitant
Cachexia Disability 9/12/2007 Male 121 lb 12/12/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/16/2007 Male 125 lb 12/13/2007 Physician Japan
Primary
Secondary
Concomitant
Stress Cardiomyopathy Hospitalization 8/24/2007 Male 104 lb 12/17/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/1/2007 Male 153 lb 12/28/2007 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 3/9/2007 Male 103 lb 12/29/2007 Physician Japan
Primary
Secondary
Concomitant
Sputum Purulent Hospitalization 10/9/2007 Female 12/27/2007 Physician Belgium
Primary
Secondary
Concomitant
Skin Infection Hospitalization 8/11/2007 Male 151 lb 12/28/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Pruritic Life Threatening 9/28/2007 Male 127 lb 1/7/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2007 Male 151 lb 1/11/2008 Consumer Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 12/11/2007 Male 153 lb 1/18/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2007 Male 103 lb 1/21/2008 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Death 3/16/2007 Male 157 lb 1/21/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/19/2007 60 Male 1/17/2008 Physician Japan
Primary
Secondary
Renal Impairment Other Serious 2/7/2007 Male 125 lb 1/17/2008 Physician Japan
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 4/26/2007 Male 160 lb 1/25/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/12/2007 Male 123 lb 1/28/2008 Physician Japan
Primary
Secondary
Concomitant
Aneurysm Hospitalization 4/24/2007 Female 95 lb 1/30/2008 Physician Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 5/19/2007 Male 174 lb 1/30/2008 Physician Japan
Primary
Secondary
Concomitant
Palpitations Hospitalization 10/19/2007 Male 152 lb 2/3/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/28/2007 Male 127 lb 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/16/2007 Male 125 lb 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 11/30/2007 Male 198 lb 1/31/2008 Physician Germany
Primary
Secondary
Renal Impairment Hospitalization 6/12/2007 Male 142 lb 2/4/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/24/2007 Female 119 lb 2/4/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/21/2007 Male 127 lb 2/5/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/30/2007 Male 141 lb 2/8/2008 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 10/15/2007 Male 105 lb 2/14/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/19/2007 Male 109 lb 2/14/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/23/2007 Male 110 lb 2/20/2008 Physician Japan
Primary
Secondary
Concomitant
Mesenteric Artery Thrombosis Hospitalization 10/30/2007 Male 143 lb 2/21/2008 Physician Hungary
Primary
Secondary
Concomitant
Shock Hospitalization 8/16/2007 Male 154 lb 3/3/2008 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 12/25/2007 Male 143 lb 3/25/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/1/2007 Male 153 lb 3/25/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/7/2007 Male 125 lb 3/26/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/19/2007 Male 109 lb 4/3/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/1/2007 Male 103 lb 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 7/6/2007 Female 90 lb 3/31/2008 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Other Serious 7/1/2007 70 Male 140 lb 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Mediastinitis Hospitalization 3/4/2008 Male 93 lb 4/4/2008 Physician India
Primary
Secondary
Concomitant
Haemothorax Hospitalization 4/21/2007 Male 158 lb 4/9/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/17/2007 Male 143 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Restlessness Other Serious 6/17/2007 Female 88 lb 4/18/2008 Physician Japan
Primary
Secondary
Concomitant

Drug Data