Cisplatin combined with Metformin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Blood Creatinine Increased Other Serious 8/20/2002 46 Female 256 lb 12/15/2005 United States
Primary
Secondary
Concomitant
Hydrocephalus Other Serious 1/8/2006 Male 162 lb 2/1/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2006 64 Male 3/28/2006 Physician United States
Primary
Concomitant
Syncope Hospitalization 7/26/2006 64 Male 205 lb 9/6/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Projectile Hospitalization 7/26/2006 62 Female 180 lb 9/11/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/26/2006 62 Female 180 lb 11/14/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Life Threatening 6/5/2006 63 Male 12/7/2006 Consumer Ireland
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 1/8/2007 Consumer Ireland
Primary
Secondary
Concomitant
Renal Failure Life Threatening 6/5/2006 63 Male 1/8/2007 Consumer Ireland
Primary
Secondary
Concomitant
Venous Thrombosis Life Threatening 11/24/2006 71 Male 1/18/2007 United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 2/2/2007 Consumer Ireland
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/17/2006 60 Male 2/20/2007 Consumer Ireland
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/2/2006 60 Male 3/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 11/16/2006 69 Male 170 lb 3/5/2007 Physician Denmark
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/15/2007 Male 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/15/2007 Male 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/23/2007 53 Male 223 lb 4/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 5/1/2007 60 Female 6/15/2007 Physician Canada
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/17/2006 60 Male 7/13/2007 Consumer Ireland
Primary
Secondary
Concomitant
Renal Failure Life Threatening 6/5/2006 63 Male 7/23/2007 Consumer Ireland
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/17/2006 60 Male 8/1/2007 Consumer Ireland
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 11/24/2006 71 Male 8/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 2/19/2006 60 Male 8/15/2007 Consumer Ireland
Primary
Secondary
Concomitant
Venous Thrombosis Life Threatening 11/24/2006 71 Male 8/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 11/24/2006 71 Male 9/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 6/20/2006 Female 191 lb 8/27/2007 United States
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 11/16/2006 69 Male 170 lb 9/19/2007 Physician Denmark
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 11/16/2006 69 Male 170 lb 10/1/2007 Physician Denmark
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/16/2007 Female 184 lb 10/18/2007 United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2007 69 Male 132 lb 11/2/2007 Physician Spain
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 12/17/2006 54 Male 108 lb 11/16/2007 Physician Singapore
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 11/27/2007 Consumer Ireland
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 11/24/2006 71 Male 12/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 11/24/2006 71 Male 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/25/2007 37 Male 185 lb 1/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 6/22/2007 66 Female 187 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/19/2006 60 Male 2/1/2008 Consumer Ireland
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/22/2008 72 Male 176 lb 4/2/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Stomatitis Hospitalization 3/17/2008 51 Male 170 lb 4/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/22/2008 Male 176 lb 4/11/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Septic Shock Life Threatening 11/24/2006 71 Male 4/15/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 11/24/2006 71 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Urea Increased Hospitalization 3/11/2008 Male 176 lb 4/18/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Peritonitis Hospitalization 2/10/2008 62 Male 158 lb 4/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oliguria Hospitalization 3/22/2008 Male 176 lb 4/28/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/11/2008 Male 176 lb 5/2/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/11/2008 Male 176 lb 5/15/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/27/2008 71 Male 185 lb 5/5/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2008 76 Male 5/28/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 4/4/2008 67 Male 209 lb 5/20/2008 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 4/4/2008 67 Male 209 lb 6/10/2008 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 4/4/2008 67 Male 209 lb 7/2/2008 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/20/2007 70 Male 181 lb 7/31/2008 Mexico
Primary
Secondary
Concomitant
Wound Infection Pseudomonas Other Serious 4/4/2008 67 Male 209 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/18/2007 70 Male 181 lb 9/18/2008 Mexico
Primary
Secondary
Concomitant
Incontinence Other Serious 3/6/2006 Male 10/3/2008 Physician Hungary
Primary
Concomitant
Tracheobronchitis Hospitalization 1/24/2007 63 Female 3/19/2007 Physician United States
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 1/19/2008 74 Male 10/20/2008 Japan
Primary
Concomitant
Renal Failure Chronic Hospitalization 3/11/2008 Male 176 lb 11/4/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/23/2007 53 Male 223 lb 11/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 11/14/2008 Male 260 lb 11/19/2008 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 5/1/2008 76 Male 12/8/2008 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/11/2008 Male 176 lb 12/26/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 11/28/2008 74 Male 12/17/2008 Physician Canada
Primary
Secondary
Concomitant
Troponin T Increased Hospitalization 12/25/2008 74 Male 1/12/2009 Physician Canada
Primary
Secondary
Concomitant
Confusional State Hospitalization 1/5/2009 Female 1/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/2/2009 63 Male 207 lb 2/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Local Swelling Hospitalization 2/1/2009 Male 2/16/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 10/1/2008 63 Male 205 lb 2/19/2009 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 12/28/2006 65 Male 209 lb 2/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 1/5/2009 Female 3/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Death 1/17/2009 65 Male 143 lb 3/10/2009 Physician Mexico
Primary
Concomitant
Sialoadenitis Hospitalization 2/1/2009 Male 3/18/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 1/19/2008 74 Male 4/3/2009 Japan
Primary
Concomitant
Oropharyngeal Pain Hospitalization 3/25/2009 59 Male 241 lb 4/3/2009 United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 3/25/2009 59 Male 242 lb 4/17/2009 Physician United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 3/25/2009 59 Male 242 lb 5/5/2009 Physician United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 3/25/2009 59 Male 242 lb 5/8/2009 Physician United States
Primary
Secondary
Concomitant
Fall Hospitalization 4/17/2009 69 Male 176 lb 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 4/17/2009 69 Male 176 lb 7/6/2009 Physician United States
Primary
Secondary
Concomitant
Renal Salt-wasting Syndrome Hospitalization 7/1/2008 Male 112 lb 7/7/2009 Physician Singapore
Primary
Secondary
Concomitant
Renal Salt-wasting Syndrome Hospitalization 7/1/2008 Male 112 lb 9/1/2009 Physician Singapore
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/21/2009 68 Male 163 lb 9/9/2009 Consumer Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/21/2009 68 Male 163 lb 9/15/2009 Consumer Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/18/2008 181 lb 9/24/2009 Physician Netherlands
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 9/24/2009 Female 198 lb 10/26/2009 Physician Netherlands
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 9/22/2009 59 Female 198 lb 10/29/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/5/2009 Female 11/3/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/23/2009 11/16/2009 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/29/2009 68 Female 11/10/2009 Consumer Denmark
Primary
Concomitant
Vomiting Hospitalization 8/23/2009 11/17/2009 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/23/2009 11/25/2009 Physician Netherlands
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 72 Male 11/30/2009 Physician United States
Primary
Concomitant
Respiratory Tract Infection Life Threatening 8/21/2009 68 Male 163 lb 12/23/2009 Consumer Germany
Primary
Secondary
Concomitant
Renal Impairment Other Serious 63 Male 1/6/2010 Other Health Professional Austria
Primary
Secondary
Vomiting Hospitalization 8/23/2009 1/6/2010 Physician Netherlands
Primary
Secondary
Concomitant
Renal Impairment Other Serious 63 Male 231 lb 1/8/2010 Other Health Professional Austria
Primary
Concomitant
Interacting
Renal Impairment Other Serious 63 Male 1/11/2010
Primary
Secondary
Concomitant
Treatment Noncompliance 11/16/2008 62 Male 9/18/2009 France
Primary
Secondary
Concomitant
Urethral Cancer Other Serious 63 Male 231 lb 1/16/2010 United States
Primary
Secondary
Urinary Tract Infection Staphylococcal Other Serious 63 Male 231 lb 1/22/2010
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/21/2009 68 Male 163 lb 2/9/2010 Consumer Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/4/2010 72 Male 2/24/2010 Physician
Primary
Secondary
Renal Failure Acute Hospitalization 1/4/2010 72 Male 2/25/2010 Other Health Professional
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/27/2009 Male 2/25/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/4/2010 72 Male 3/15/2010 Physician
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/21/2009 68 Male 163 lb 3/17/2010 Consumer Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/4/2010 72 Male 3/23/2010 Physician
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/4/2010 72 Male 3/24/2010 Other Health Professional
Primary
Secondary
Concomitant
Streptococcal Sepsis Hospitalization 11/23/2009 Male 209 lb 3/24/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/25/2010 62 Female 3/25/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/13/2010 Female 220 lb 3/25/2010 Physician Germany
Primary
Secondary
Concomitant
Sudden Death Other Serious 3/29/2010 56 Male 181 lb 4/19/2010 Consumer United States
Primary
Secondary
Concomitant
Infection Other Serious 2/25/2008 62 Male 165 lb 4/21/2010 Physician Germany
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/18/2007 70 Male 172 lb 4/30/2010 Mexico
Primary
Secondary
Concomitant
Sudden Death Other Serious 3/29/2010 56 Male 181 lb 5/12/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/18/2009 56 Female 175 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/5/2009 75 Female 6/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Headache 10/1/2008 13 Male 6/24/2010 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 7/10/2010 65 168 lb 7/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vision Blurred 10/1/2007 70 Male 260 lb 8/3/2010 Consumer United States
Primary
Concomitant
Radiation Oesophagitis Hospitalization 4/5/2010 54 Male 199 lb 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Swelling Face Life Threatening 6/21/2010 64 Male 8/10/2010 Consumer United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/10/2010 65 168 lb 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 7/28/2010 58 Male 8/13/2010 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 3/29/2010 56 Male 181 lb 8/13/2010 Physician Turkey
Primary
Secondary
Concomitant
Swelling Face Life Threatening 6/21/2010 64 Male 8/16/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 4/23/2010 55 Male 8/20/2010 Physician France
Primary
Concomitant
Sudden Death Death Male 165 lb 8/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Venous Stent Insertion Hospitalization Male 8/31/2010 Other Health Professional Canada
Primary
Concomitant
Atrial Fibrillation Hospitalization 7/28/2010 58 Male 182 lb 8/31/2010 Physician Canada
Primary
Secondary
Concomitant
Respiratory Tract Infection Life Threatening 8/21/2009 68 Male 163 lb 9/8/2010 Consumer Germany
Primary
Secondary
Concomitant
Urinary Hesitation Hospitalization 10/11/2010 52 Male 255 lb 10/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/10/2010 65 168 lb 11/11/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 8/23/2010 55 Male 255 lb 11/22/2010 Physician Canada
Primary
Secondary
Concomitant
Odynophagia Hospitalization 11/15/2010 62 Female 12/9/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 12/6/2010 68 Male 178 lb 12/14/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 12/6/2010 68 Male 179 lb 12/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Odynophagia Hospitalization 11/15/2010 62 Female 2/2/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Hospitalization 12/3/2010 53 Male 250 lb 2/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 2/8/2011 51 Male 209 lb 4/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 3/27/2011 56 Male 5/10/2011 Physician Italy
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 4/1/2011 62 Male 175 lb 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 4/15/2011 62 Male 168 lb 4/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 3/27/2011 56 Male 5/16/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Stomatitis Hospitalization 3/27/2011 56 Male 5/25/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 6/8/2011 74 Male 6/21/2011 Physician Switzerland
Primary
Secondary
Concomitant
Orthostatic Hypotension Other Serious 10/9/2008 60 Male 6/22/2011 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/5/2011 65 Male 174 lb 6/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Marrow Oedema Other Serious Female 6/27/2011 Other Health Professional United States
Primary
Concomitant

Drug Data