Cisplatin combined with Mesna

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neurotoxicity Death 36 Female 1/5/2006 Physician Turkey
Primary
Secondary
Concomitant
Swelling Death 36 Female 1/31/2006 Physician Turkey
Primary
Secondary
Swelling Death 36 Female 2/13/2006 Physician Turkey
Primary
Secondary
Therapy Non-responder Death 36 Female 2/14/2006 Physician Turkey
Primary
Secondary
T-cell Lymphoma Hospitalization 36 Female 3/17/2006 Physician Turkey
Primary
Secondary
Thrombocytopenia Life Threatening 3/6/2006 53 Female 4/13/2006 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Streptococcal Other Serious 7/1/2004 52 Male 6/14/2006 Other Health Professional Korea, Republic Of
Primary
Secondary
Small Cell Carcinoma Hospitalization 52 Male 7/11/2006 Physician Korea, Republic Of
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 36 Female 7/14/2006 Other Health Professional Turkey
Primary
Secondary
Pneumonia Streptococcal Hospitalization 52 Male 8/14/2006 Physician Korea, Republic Of
Primary
Secondary
Gastritis Hospitalization 6/19/2006 40 Female 115 lb 9/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/2/2006 Female 51 lb 11/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 1/14/2007 Female 14 lb 1/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/17/2007 57 Female 117 lb 4/4/2007 Consumer United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 36 Female 5/25/2007 Physician Turkey
Primary
Secondary
Stem Cell Transplant Death 6/25/2007 Male 40 lb 7/3/2007 Physician United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 3 Male 35 lb 8/28/2007
Primary
Secondary
Haematotoxicity Other Serious 9/14/2007 Consumer United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 16 Female 11/20/2007 Other Health Professional Australia
Primary
Secondary
Pancreatitis Acute Hospitalization 5/14/2008 Male 7/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Neurotoxicity Life Threatening 1/1/2007 37 Male 7/28/2008 Consumer United States
Primary
Secondary
Concomitant
Musculoskeletal Pain Hospitalization 6/17/2008 21 Male 121 lb 7/29/2008 Other Health Professional Colombia
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2007 37 Male 7/29/2008 India
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 8/1/2000 34 Female 130 lb 10/10/2008 Physician United States
Primary
Secondary
Liver Abscess Death 5/25/2008 1 Male 22 lb 10/10/2008 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Life Threatening 5/25/2008 1 NotSpecified 22 lb 10/30/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/25/2008 1 Male 22 lb 11/12/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/25/2008 1 Male 22 lb 11/17/2008 Physician Japan
Primary
Concomitant
Sinusitis Other Serious 7/1/2008 61 Female 12/3/2008 Consumer United Kingdom
Primary
Concomitant
Sinusitis Other Serious 7/1/2008 61 Female 12/9/2008 Consumer United Kingdom
Primary
Concomitant
Epilepsy Other Serious 11/7/2008 27 Male 2/3/2009 Pharmacist Norway
Primary
Secondary
Muscle Twitching Other Serious 11/14/2008 60 Male 2/5/2009 Physician Norway
Primary
Secondary
Concomitant
Encephalopathy Other Serious 12/30/2008 64 Female 2/5/2009 Physician Norway
Primary
Secondary
Encephalopathy Other Serious 12/16/2008 33 Male 2/6/2009 Physician Norway
Primary
Secondary
Concomitant
Epilepsy Other Serious 11/7/2008 27 Male 2/25/2009 Pharmacist Norway
Primary
Secondary
Concomitant
Encephalopathy Other Serious 12/16/2008 33 Male 2/25/2009 Physician Norway
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 11/14/2008 60 Male 2/25/2009 Physician Norway
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/30/2008 64 Female 2/25/2009 Physician Norway
Primary
Secondary
Concomitant
Epilepsy Other Serious 11/7/2008 27 Male 2/27/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Speech Disorder Other Serious 12/1/2008 33 Male 2/27/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Encephalopathy Other Serious 12/16/2008 3/6/2009 Physician Norway
Primary
Secondary
Concomitant
Confusional State Other Serious 12/16/2008 33 Male 3/6/2009 Physician Netherlands
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 11/14/2008 3/11/2009 Physician Norway
Primary
Secondary
Concomitant
Speech Disorder Other Serious 12/1/2008 33 Male 3/25/2009 Pharmacist Norway
Primary
Secondary
Concomitant
Encephalopathy Other Serious 12/16/2008 3/31/2009 Pharmacist Norway
Primary
Secondary
Concomitant
Myoclonic Epilepsy Hospitalization 2/27/2007 74 Female 4/1/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Neurotoxicity Hospitalization 2/27/2007 74 Female 4/8/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5 Female 6/29/2009 Taiwan, Province Of China
Primary
Secondary
Encephalopathy Other Serious 12/16/2008 33 7/10/2009 Pharmacist Norway
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 3/16/2009 14 Female 7/17/2009 Other Health Professional France
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1 Male 7/24/2009 Other Health Professional Lebanon
Primary
Secondary
Speech Disorder Other Serious 12/1/2008 33 Male 8/7/2009 Pharmacist Norway
Primary
Secondary
Concomitant
Neoplasm Progression Other Serious 69 Female 8/7/2009
Primary
Secondary
Concomitant
Osteonecrosis Disability 3/1/2008 Male 8/12/2009 Other Health Professional Italy
Primary
Concomitant
Hyponatraemia Other Serious 69 Female 8/31/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Restlessness Other Serious 33 Male 9/10/2009 Other Health Professional Norway
Primary
Secondary
Muscle Twitching Other Serious 60 Male 9/10/2009 Other Health Professional Norway
Primary
Secondary
Therapeutic Response Decreased Male 9/16/2009 Pharmacist United States
Primary
Concomitant
Osteonecrosis Disability 3/1/2008 Male 9/17/2009 Other Health Professional Italy
Primary
Concomitant
Venoocclusive Disease Hospitalization 8/25/2009 Male 33 lb 9/23/2009 United States
Primary
Secondary
Sepsis Death 10/2/2009 Physician United States
Primary
Concomitant
Urosepsis Death 10/2/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 8/25/2009 Male 33 lb 10/5/2009 United States
Primary
Secondary
Sepsis Death 10/29/2009 Physician United States
Primary
Concomitant
Urosepsis Death Female 11/11/2009 Physician United States
Primary
Concomitant
Sepsis Death 12/1/2009 Physician United States
Primary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/9/2010 Male 126 lb 2/3/2010 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 3/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 4/7/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/7/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Encephalopathy Other Serious 12/30/2008 64 Female 4/8/2010 Physician Norway
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 4/23/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 6/15/2010 Lawyer United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 1/9/2010 20 Male 126 lb 7/5/2010 Physician France
Primary
Concomitant
Renal Failure Other Serious 6/18/2010 76 Male 216 lb 8/5/2010 Physician United States
Primary
Concomitant
Interacting
Klebsiella Sepsis Hospitalization 8/14/2010 59 Male 186 lb 8/27/2010 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 10/11/2010 Lawyer United States
Primary
Concomitant
Restlessness Other Serious 12/16/2008 33 Male 10/6/2010 Other Health Professional Norway
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/9/2010 59 Male 186 lb 11/23/2010 Physician United States
Primary
Secondary
Klebsiella Sepsis Hospitalization 8/14/2010 59 Male 186 lb 11/24/2010 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 12/2/2010 Lawyer United States
Primary
Concomitant
Febrile Neutropenia Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Febrile Neutropenia Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Febrile Neutropenia Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Febrile Neutropenia Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Stomatitis Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Stomatitis Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Neutropenic Sepsis Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Ototoxicity Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Ototoxicity Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Nephropathy Toxic Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Multi-organ Failure Death 7/1/2007 1 Male 18 lb 1/27/2011 Physician United States
Primary
Concomitant
Myeloid Leukaemia Other Serious 2/7/2011 Physician France
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 2/7/2011 Physician France
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 4/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Death 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 3/23/2008 65 Male 5/26/2011 Physician France
Primary
Secondary
Concomitant
Cardiotoxicity Other Serious 15 Female 5/27/2011 Other Health Professional Norway
Primary
Secondary
Concomitant
Cardiotoxicity Other Serious 15 Female 5/27/2011 Other Health Professional Norway
Primary
Secondary
Concomitant
Cardiotoxicity Life Threatening 15 Female 6/1/2011 Other Health Professional Sweden
Primary
Secondary
Neuropathy Peripheral Other Serious 1/1/2008 65 Male 6/2/2011 Lawyer France
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11 Male 6/21/2011 Physician United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Other Serious 10/9/2008 60 Male 6/22/2011 Physician United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 3/23/2008 65 Male 6/23/2011 Physician France
Primary
Secondary
Concomitant
Septic Shock Death 7/20/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Septic Shock Death 7/20/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Septic Shock Death 7/20/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Septic Shock Death 8/8/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Septic Shock Death 8/8/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Septic Shock Death 8/8/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 18 Male 8/17/2011 Other Health Professional Brazil
Primary
Secondary
Concomitant
Neutropenia Death 11 Female 8/17/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Neutropenia Death 15 Female 8/17/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death Male 8/19/2011 Brazil
Primary
Secondary
Cardiotoxicity Life Threatening 15 Female 9/2/2011 Other Health Professional Romania
Primary
Secondary
Leukopenia Other Serious 11 Male 9/12/2011 Pharmacist United States
Primary
Secondary
Sepsis Life Threatening 4/16/2011 61 Male 185 lb 9/13/2011 Other Health Professional Denmark
Primary
Secondary
Thrombocytopenia Hospitalization 8/24/2001 43 Male 160 lb 9/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Neoplasm Progression Death 8/24/2010 43 Male 158 lb 9/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 3/31/2011 59 Male 170 lb 9/22/2011 Consumer Denmark
Primary
Secondary
Infection Hospitalization 3/29/2011 59 Male 170 lb 9/22/2011 Physician Denmark
Primary
Secondary
Disturbance In Attention Hospitalization 3/26/2011 59 Male 170 lb 9/27/2011 Consumer Denmark
Primary
Secondary
Electrolyte Imbalance Other Serious 10/11/2011 Other Health Professional United States
Primary
Secondary
Embolism Venous Other Serious 10/11/2011 Other Health Professional United States
Primary
Secondary
Wound Complication Other Serious 10/11/2011 Other Health Professional United States
Primary
Secondary
Wound Complication Other Serious 10/12/2011 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Death Female 10/24/2011 Other Health Professional France
Primary
Secondary
Death Death Female 10/25/2011 Other Health Professional France
Primary
Secondary
Nephropathy Toxic Other Serious Female 10/26/2011 Other Health Professional France
Primary
Secondary
Pyrexia Other Serious 11 Male 10/25/2011 United States
Primary
Secondary
Concomitant
Lung Infection Other Serious 10/21/2011 19 Male 145 lb 11/9/2011 Physician United States
Primary
Secondary
Infection Hospitalization 2/15/2005 17 11/21/2011 United States
Primary
Secondary
Convulsion Life Threatening 6/14/2005 20 11/21/2011 United States
Primary
Secondary
Pyrexia Hospitalization 10/10/2001 11 Male 11/29/2011 Physician United States
Primary
Secondary
Renal Tubular Necrosis Hospitalization 52 Male 12/14/2011 Other Health Professional France
Primary
Secondary
Renal Failure Acute Other Serious 52 Male 12/20/2011 Physician France
Primary
Secondary
Renal Failure Hospitalization 52 Male 12/22/2011 Other Health Professional France
Primary
Secondary
Pyrexia Hospitalization 10/1/2001 11 Male 12/22/2011 Consumer United States
Primary
Secondary
Infection Life Threatening 12/8/2001 12 Male 12/23/2011 Physician United States
Primary
Secondary
Haemodialysis Other Serious 52 Male 12/27/2011 France
Primary
Secondary
Concomitant
Hypotension Other Serious 18 Male 1/4/2012 Other Health Professional United States
Primary
Secondary
Renal Tubular Necrosis Hospitalization 7/1/2011 66 Female 1/10/2012 Other Health Professional France
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 1/14/2012 2 Female 35 lb 1/18/2012 Physician United States
Primary
Secondary
Infection Hospitalization 1/29/2009 3 Female 35 lb 2/10/2012 Physician Japan
Primary
Concomitant
Pericardial Effusion Hospitalization 11/21/2004 16 2/16/2012 United States
Primary
Secondary
Infection Hospitalization 10/10/2001 11 Male 2/17/2012 Physician United States
Primary
Secondary
Hyponatraemia Other Serious 1/4/2004 21 Female 2/28/2012 Physician United States
Primary
Secondary

Drug Data