Cisplatin combined with Loxonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Arrest Other Serious 9/22/2005 60 Male 144 lb 1/24/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 6/3/2006 63 Male 121 lb 8/4/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/14/2006 Male 8/10/2006 Pharmacist Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/1/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/5/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/3/2006 63 Male 121 lb 10/3/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 6/3/2006 63 Male 121 lb 10/11/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 6/3/2006 63 Male 121 lb 10/24/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased 5/29/2006 Male 10/31/2006 Pharmacist Japan
Primary
Concomitant
Septic Shock Other Serious 11/28/2006 57 Female 88 lb 1/27/2007 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 11/28/2006 57 Female 88 lb 2/7/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/23/2007 65 Male 110 lb 3/21/2007 Physician Japan
Primary
Secondary
Concomitant
Pseudomembranous Colitis Hospitalization 2/23/2007 65 Male 110 lb 4/4/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 7/5/2007 61 Male 121 lb 7/18/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/1/2005 66 Male 8/15/2007 Consumer United States
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Other Serious 2/7/2007 72 Male 125 lb 8/7/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/1/2005 66 Male 8/28/2007 Consumer Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/1/2005 66 Male 9/4/2007 Consumer Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/27/2005 65 Male 9/21/2007 Consumer Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/26/2007 Male 10/1/2007 Other Health Professional Japan
Primary
Secondary
Pyrexia Other Serious 8/26/2007 Male 10/2/2007 Other Health Professional Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/23/2007 Male 84 lb 10/1/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/27/2005 65 Male 10/11/2007 Consumer Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 8/26/2007 Male 10/19/2007 Other Health Professional Japan
Primary
Secondary
Rhabdomyolysis Other Serious 8/26/2007 Male 10/31/2007 Other Health Professional Japan
Primary
Secondary
Anaphylactic Reaction Life Threatening 10/5/2007 Male 108 lb 10/28/2007 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 3/6/2007 Male 123 lb 10/18/2007 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Other Serious 5/1/2007 Male 10/30/2007 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 8/26/2007 Male 11/7/2007 Other Health Professional Japan
Primary
Secondary
Weight Decreased Hospitalization 4/11/2007 71 Male 119 lb 12/4/2007 Other Health Professional United States
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 9/28/2007 Male 127 lb 11/27/2007 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 9/3/2007 Male 147 lb 11/27/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 7/24/2007 59 Male 148 lb 12/4/2007 Consumer United States
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 9/3/2007 59 Male 148 lb 12/10/2007 Consumer United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 9/28/2007 Male 127 lb 12/5/2007 Physician Japan
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 10/5/2007 Male 108 lb 12/9/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/24/2007 Female 119 lb 12/9/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Pruritic Life Threatening 9/28/2007 Male 127 lb 1/7/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/22/2007 Male 144 lb 1/21/2008 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 2/7/2007 Male 125 lb 1/17/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/7/2007 72 Male 126 lb 1/28/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/23/2005 Female 101 lb 1/22/2008 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 2/7/2007 72 Male 126 lb 1/31/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/7/2007 72 Male 126 lb 2/1/2008 Consumer United States
Primary
Secondary
Concomitant
Palpitations Hospitalization 10/19/2007 Male 152 lb 2/3/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/28/2007 Male 127 lb 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/24/2007 Female 119 lb 2/4/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/23/2007 Male 110 lb 2/20/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/22/2007 Male 144 lb 3/11/2008 Physician Japan
Primary
Concomitant
Tracheal Fistula Hospitalization 8/9/2007 Female 3/17/2008 Japan
Primary
Secondary
Concomitant
Tracheal Fistula Hospitalization 8/9/2007 Female 3/28/2008 Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 2/7/2007 72 Male 126 lb 4/1/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/7/2007 Male 125 lb 3/26/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/23/2005 Female 101 lb 3/28/2008 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 11/17/2007 46 Male 143 lb 4/16/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/17/2007 Male 143 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2008 Male 142 lb 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 4/1/2008 Male 142 lb 5/1/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/31/2008 Male 114 lb 5/21/2008 Physician Japan
Primary
Secondary
Concomitant
Palpitations Hospitalization 10/17/2007 Male 152 lb 5/27/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 4/1/2008 Male 142 lb 6/5/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/7/2007 Male 143 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/17/2007 46 Male 143 lb 7/7/2008 Consumer United States
Primary
Secondary
Concomitant
Performance Status Decreased Hospitalization 11/29/2007 Male 137 lb 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/23/2008 Male 114 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/11/2007 Male 118 lb 7/30/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/5/2007 46 Male 143 lb 8/25/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/17/2007 Male 152 lb 8/29/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/31/2008 Male 164 lb 9/5/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/5/2007 Male 143 lb 9/16/2008 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Death 9/2/2008 Female 99 lb 10/2/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/23/2008 Male 114 lb 9/25/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/29/2007 Male 137 lb 10/6/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/23/2008 Male 104 lb 10/16/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/25/2007 Male 130 lb 10/29/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 10/3/2008 55 Male 11/20/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 12/16/2008 Physician Japan
Primary
Secondary
Concomitant
Syncope Other Serious 10/14/2008 61 Male 12/17/2008 Japan
Primary
Secondary
Concomitant
Vena Cava Thrombosis Hospitalization 9/1/2008 Male 151 lb 12/29/2008 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 9/25/2007 Male 154 lb 1/27/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 12/30/2008 2/9/2009 Other Health Professional Japan
Primary
Secondary
Syncope Other Serious 10/14/2008 61 Male 12/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/29/2007 Male 137 lb 3/2/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/29/2007 Male 137 lb 3/31/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/2/2008 Female 93 lb 5/20/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/2/2008 58 Female 93 lb 5/26/2009 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/4/2008 Female 87 lb 6/9/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/30/2009 Male 116 lb 6/23/2009 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 1/1/2009 Female 153 lb 11/5/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/23/2007 Male 110 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 3/6/2007 Male 123 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/23/2007 Male 84 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/11/2007 Male 118 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Other Serious 4/27/2007 Male 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/28/2007 Male 127 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 10/5/2007 Male 108 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/22/2007 Male 144 lb 11/30/2009 Physician Japan
Primary
Concomitant
Palpitations Hospitalization 10/17/2007 Male 152 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 4/1/2008 Male 142 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/5/2007 Male 143 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/29/2007 Male 137 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/2/2008 Female 93 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/25/2007 Male 154 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
Vena Cava Thrombosis Hospitalization 9/1/2008 Male 151 lb 12/1/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 4/30/2009 Male 116 lb 2/8/2010 Physician Japan
Primary
Concomitant
Gastric Ulcer Other Serious 10/29/2009 Female 119 lb 2/15/2010 Physician Japan
Primary
Concomitant
Gastric Ulcer Hospitalization 10/29/2009 Female 119 lb 3/15/2010 Physician Japan
Primary
Concomitant
Rectal Ulcer Hospitalization 2/23/2010 45 Female 82 lb 8/5/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 8/3/2010 42 90 lb 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 8/17/2010 31 101 lb 8/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 8/17/2010 31 101 lb 9/2/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/3/2010 42 90 lb 9/6/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Oesophageal Carcinoma Other Serious 6/22/2010 76 Male 115 lb 9/15/2010 Physician Japan
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 2/23/2010 45 Female 82 lb 9/17/2010 Physician Japan
Primary
Concomitant
Sputum Culture Positive Death 4/30/2009 71 Male 116 lb 10/7/2010 Physician Japan
Primary
Concomitant
Oesophageal Carcinoma Other Serious 6/22/2010 76 Male 115 lb 10/15/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/16/2010 63 Male 120 lb 10/29/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 1/1/2010 55 Male 157 lb 12/23/2010 Physician Japan
Primary
Concomitant
Haematochezia Hospitalization 1/1/2010 55 Male 157 lb 1/25/2011 Physician Japan
Primary
Concomitant
Drug Ineffective Death 12/17/2009 60 Male 110 lb 2/28/2011 Physician Japan
Primary
Secondary
Concomitant
Cystitis Other Serious 12/11/2010 65 Female 4/4/2011 Physician Japan
Primary
Concomitant
Dehydration Other Serious 1/1/2010 55 Male 157 lb 5/24/2011 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Hospitalization 6/5/2010 55 Male 157 lb 6/1/2011 Other Health Professional Japan
Primary
Concomitant
Anal Abscess Other Serious 8/11/2010 55 Male 157 lb 6/2/2011 Other Health Professional Japan
Primary
Concomitant
Neutropenia Hospitalization 2/11/2011 61 Male 7/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neurogenic Bladder Other Serious 12/11/2010 65 Female 7/21/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 3/18/2011 64 Male 132 lb 7/29/2011 Consumer Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/29/2009 60 Female 126 lb 8/3/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/28/2009 56 Female 101 lb 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/11/2011 61 Male 9/9/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cystitis Other Serious 12/11/2010 65 Female 9/26/2011 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/21/2009 60 Female 126 lb 10/11/2011 Physician Japan
Primary
Concomitant
Myocardial Infarction Other Serious 11/9/2011 48 Female 132 lb 12/19/2011 Consumer Japan
Primary
Concomitant
Metastasis Other Serious 11/9/2011 48 Female 132 lb 12/27/2011 Physician Japan
Primary
Concomitant
Acidosis Other Serious 12/17/2009 63 Male 110 lb 1/10/2012 Physician Japan
Primary
Secondary
Concomitant
Melaena Death 7/1/2011 71 Male 1/17/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 12/21/2011 70 Male 2/3/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 12/21/2009 60 Female 126 lb 3/13/2012 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Other Serious 1/31/2012 61 Male 90 lb 6/11/2012 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 8/1/2011 57 Female 123 lb 7/10/2012 Consumer Japan
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 8/1/2011 57 Female 123 lb 7/30/2012 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 8/1/2011 57 Female 123 lb 8/26/2012 Consumer Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/30/2009 71 Male 116 lb 4/22/2013 Physician Jp
Primary
Concomitant
Pneumothorax Death 3/16/2010 67 Male 130 lb 11/16/2012 Physician Jp
Primary
Secondary
Concomitant
Renal Impairment Death 11/3/2012 77 Male 123 lb 6/13/2013 Physician Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/16/2012 69 Male 7/26/2013 Consumer Jp
Primary
Concomitant
Renal Impairment Other Serious 2013 63 Male 7/15/2013 Pharmacist Jp
Primary
Concomitant

Drug Data