Cisplatin combined with Iressa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Brain Stem Haemorrhage Life Threatening 8/7/2005 71 Female 1/5/2006 Physician Japan
Primary
Concomitant
Chromaturia Hospitalization 8/13/2005 50 Female 117 lb 1/19/2006 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 10/15/2005 63 Male 1/23/2006 Physician Belgium
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 9/22/2005 60 Male 144 lb 1/24/2006 Physician Japan
Primary
Concomitant
Sudden Death Death 11/3/2005 Male 1/31/2006 Physician Poland
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 1/28/2006 Male 210 lb 2/7/2006 United States
Primary
Secondary
Pulmonary Embolism Hospitalization 9/15/2005 57 Male 152 lb 2/10/2006 Physician Japan
Primary
Concomitant
Blood Creatinine Increased Other Serious 2/4/2006 63 Male 2/17/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 2/4/2006 63 Male 2/22/2006 Physician Germany
Primary
Secondary
Concomitant
Vascular Insufficiency Hospitalization 1/31/2006 55 Male 149 lb 2/27/2006 Other Health Professional United States
Primary
Secondary
Anaemia Other Serious 2/16/2006 67 Male 168 lb 3/6/2006 Physician Germany
Primary
Secondary
Stomatitis Hospitalization 1/19/2006 55 Male 117 lb 3/10/2006 Physician Japan
Primary
Concomitant
Stomatitis Necrotising Disability 12/7/2004 53 Male 110 lb 3/10/2006 Physician Spain
Primary
Secondary
Purpura Hospitalization 12/27/2005 58 Female 3/15/2006 Physician Japan
Primary
Concomitant
Mucosal Inflammation Hospitalization 11/8/2004 51 Male 142 lb 3/16/2006 Physician Spain
Primary
Secondary
Concomitant
Gastric Ulcer Perforation Other Serious 11/5/2005 68 Male 3/17/2006 Physician Poland
Primary
Secondary
Concomitant
Gastrointestinal Disorder Hospitalization 3/3/2006 67 Male 132 lb 3/23/2006 Physician Belgium
Primary
Concomitant
Gastric Ulcer Perforation Other Serious 11/5/2005 68 Male 3/23/2006 Physician Poland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/3/2006 67 Male 132 lb 3/30/2006 Physician Belgium
Primary
Concomitant
Gastric Ulcer Perforation Other Serious 11/5/2005 68 Male 4/4/2006 Physician Poland
Primary
Secondary
Concomitant
Fatigue Hospitalization 11/3/2005 Male 4/11/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/2/2006 67 Male 132 lb 4/12/2006 Physician Belgium
Primary
Concomitant
Sudden Death Disability 11/3/2005 Male 4/14/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 4/21/2006 Physician Poland
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Life Threatening 8/7/2005 71 Female 4/25/2006 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 3/22/2006 66 Female 4/28/2006 Physician Poland
Primary
Secondary
Concomitant
Rash Hospitalization 12/18/2004 69 Female 84 lb 4/28/2006 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 3/22/2006 66 Female 5/4/2006 Physician Poland
Primary
Secondary
Concomitant
Nausea Other Serious 3/1/2006 80 Male 181 lb 5/19/2006 Physician Germany
Primary
Secondary
Renal Failure Hospitalization 3/28/2006 73 Male 159 lb 5/22/2006 Physician France
Primary
Secondary
Concomitant
Chest Pain Hospitalization 5/24/2006 59 Male 214 lb 5/25/2006 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/8/2004 51 Male 142 lb 6/1/2006 Physician Spain
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2006 80 Male 181 lb 6/1/2006 Physician Germany
Primary
Secondary
Concomitant
Rash Hospitalization 12/18/2004 69 Female 84 lb 6/8/2006 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 3/28/2006 73 Male 159 lb 6/9/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/28/2006 73 Male 159 lb 6/15/2006 Physician France
Primary
Secondary
Concomitant
Rash Disability 1/8/2004 49 Female 6/20/2006 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 7/16/2004 65 Male 6/21/2006 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Recurrence Disability 11/5/2004 72 Male 6/21/2006 Physician Japan
Primary
Secondary
Concomitant
Pharyngeal Fistula Hospitalization 6/12/2006 48 Male 143 lb 6/26/2006 Physician Australia
Primary
Secondary
Concomitant
Skin Reaction Other Serious 6/8/2006 65 Male 143 lb 6/26/2006 Physician France
Primary
Secondary
Concomitant
Pharyngeal Fistula Hospitalization 6/12/2006 48 Male 143 lb 6/30/2006 Physician Australia
Primary
Secondary
Concomitant
Protein Total Decreased Hospitalization 5/4/2006 64 Female 7/5/2006 Physician Belgium
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Life Threatening 6/26/2006 62 Female 7/13/2006 Physician Germany
Primary
Secondary
Concomitant
Skin Reaction Other Serious 6/8/2006 65 Male 143 lb 7/24/2006 Physician France
Primary
Secondary
Concomitant
Peritonitis Life Threatening 6/26/2006 62 Female 8/2/2006 Physician Germany
Primary
Secondary
Concomitant
Radiation Skin Injury Other Serious 6/8/2006 65 Male 143 lb 8/3/2006 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/3/2006 63 Male 121 lb 8/4/2006 Physician Japan
Primary
Concomitant
Helicobacter Pylori Identification Test Positive Hospitalization 7/17/2006 47 Male 8/4/2006 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/3/2005 49 Male 8/21/2006 Physician India
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 8/15/2006 8/29/2006 Physician United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/1/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/5/2006 Physician Japan
Primary
Secondary
Concomitant
Polyneuropathy Disability 8/1/2004 42 Female 176 lb 9/7/2006 Pharmacist France
Primary
Concomitant
Platelet Count Decreased Death 4/1/2006 69 Male 9/13/2006 Physician China
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Treatment Noncompliance Death 4/1/2006 69 Male 9/18/2006 Physician China
Primary
Concomitant
Respiratory Failure Death 8/22/2006 59 Female 88 lb 9/18/2006 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 9/4/2006 63 Male 9/18/2006 Physician Australia
Primary
Secondary
Concomitant
Staphylococcal Abscess Other Serious 7/17/2006 65 Male 119 lb 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 9/4/2006 63 Male 9/21/2006 Physician Australia
Primary
Secondary
Concomitant
Staphylococcal Abscess Other Serious 7/17/2006 65 Male 119 lb 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Polyneuropathy Disability 8/1/2004 42 Female 176 lb 9/26/2006 Pharmacist France
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 3/22/2006 66 Female 9/29/2006 Physician Poland
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/3/2006 63 Male 121 lb 10/3/2006 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 9/20/2006 46 Female 10/3/2006 Physician Italy
Primary
Concomitant
Respiratory Failure Hospitalization 6/3/2006 63 Male 121 lb 10/11/2006 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 9/20/2006 46 Female 10/13/2006 Physician Italy
Primary
Concomitant
Polyneuropathy Other Serious 8/1/2004 42 Female 176 lb 10/13/2006 Pharmacist France
Primary
Concomitant
Throat Irritation Other Serious 6/9/2006 48 Female 10/17/2006 Physician India
Primary
Concomitant
Mucosal Inflammation Hospitalization 11/8/2004 51 Male 142 lb 10/24/2006 Physician Spain
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/3/2006 63 Male 121 lb 10/24/2006 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Disability 10/12/2006 75 Male 10/24/2006 Physician Japan
Primary
Concomitant
Therapy Non-responder Death 9/19/2006 72 Female 68 lb 10/24/2006 Physician Japan
Primary
Concomitant
Pyrexia Death 9/1/2006 76 Male 141 lb 10/31/2006 Physician Japan
Primary
Concomitant
Drug Ineffective Death 9/1/2006 76 Male 141 lb 11/3/2006 Physician Japan
Primary
Concomitant
Polyneuropathy Other Serious 8/1/2004 62 Female 176 lb 11/14/2006 Pharmacist France
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 9/20/2006 46 Female 11/17/2006 Physician Italy
Primary
Concomitant
Vomiting Hospitalization 11/4/2006 63 Female 11/22/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Vertigo Hospitalization 11/4/2006 63 Female 11/30/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Pneumonia Life Threatening 3/7/2006 80 Female 157 lb 12/4/2006 Physician Philippines
Primary
Concomitant
Spinal Disorder Other Serious 9/18/2006 51 Male 150 lb 12/21/2006 Physician Japan
Primary
Concomitant
Treatment Noncompliance Hospitalization 4/1/2006 69 Male 12/26/2006 Physician China
Primary
Concomitant
Respiratory Arrest Other Serious 4/20/2005 44 Female 12/27/2006 Physician France
Primary
Concomitant
Thrombocytopenic Purpura Hospitalization 9/20/2006 46 Female 1/9/2007 Physician Italy
Primary
Concomitant
Acute Myocardial Infarction Death 1/17/2007 68 Male 89 lb 1/22/2007 Physician Singapore
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 11/16/2006 58 Male 123 lb 2/6/2007 Physician France
Primary
Secondary
Muscular Weakness Disability 12/1/2006 59 Male 234 lb 2/6/2007 Physician Russian Federation
Primary
Concomitant
Muscular Weakness Disability 12/1/2006 59 Male 234 lb 2/12/2007 Physician Russian Federation
Primary
Concomitant
Myocardial Ischaemia Death 1/17/2007 68 Male 89 lb 2/14/2007 Physician Singapore
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 6/26/2006 62 Female 2/19/2007 Physician Germany
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 1/17/2007 68 Male 89 lb 2/21/2007 Physician Singapore
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 1/17/2007 68 Male 89 lb 2/21/2007 Physician Singapore
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/26/2007 51 Male 154 lb 3/7/2007 Physician Germany
Primary
Secondary
Alopecia Other Serious 1/20/2005 67 Female 168 lb 4/8/2005 Other Health Professional United States
Primary
Concomitant
Haemoptysis Other Serious 5/1/2004 52 Male 185 lb 10/12/2004 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 62 Female 170 lb 10/12/2004 United States
Primary
Concomitant
Neuropathy Other Serious 12/1/2004 Male 8/2/2006 Pharmacist United States
Primary
Secondary
Alopecia Other Serious 1/20/2005 67 Female 168 lb 4/8/2005 Other Health Professional United States
Primary
Concomitant
Neuropathy Other Serious 12/1/2004 Male 8/2/2006 Pharmacist United States
Primary
Secondary
General Physical Health Deterioration Hospitalization 11/16/2006 58 Male 123 lb 3/26/2007 Physician France
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 12/12/2006 80 Female 112 lb 4/11/2007 Physician Japan
Primary
Concomitant
Respiratory Distress Hospitalization 3/17/2007 Male 152 lb 4/19/2007 Other Health Professional United States
Primary
Secondary
Interstitial Lung Disease Other Serious 11/25/2006 55 Male 101 lb 4/25/2007 Pharmacist Japan
Primary
Concomitant
Renal Failure Acute Death 60 Male 4/25/2007 Physician China
Primary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 4/27/2007 Physician Poland
Primary
Secondary
Concomitant
Renal Failure Acute Death 60 Male 5/1/2007 Physician China
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/3/2007 43 Female 5/4/2007 Physician Korea, Republic Of
Primary
Concomitant
Acute Myeloid Leukaemia Death 2/6/2007 71 Female 5/11/2007 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 4/3/2007 43 Female 5/14/2007 Physician Korea, Republic Of
Primary
Concomitant
Acute Myeloid Leukaemia Death 2/6/2007 71 Female 84 lb 5/14/2007 Physician Japan
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Disability 1/3/2007 64 Male 157 lb 5/21/2007 Physician Japan
Primary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 5/25/2007 Physician Poland
Primary
Secondary
Concomitant
Pneumonia Life Threatening 3/7/2006 80 Female 157 lb 5/25/2007 Physician Philippines
Primary
Concomitant
Gastric Ulcer Hospitalization 7/17/2006 47 Male 6/4/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Haematemesis Other Serious 12/3/2005 49 Male 6/5/2007 Physician India
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/19/2007 65 Male 174 lb 6/5/2007 Physician Singapore
Primary
Concomitant
Renal Failure Acute Death 4/6/2007 60 Female 6/28/2007 Physician China
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 3/22/2006 66 Female 7/3/2007 Physician Poland
Primary
Secondary
Concomitant
Stomatitis Death 1/15/2007 71 Male 7/9/2007 Physician Poland
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/28/2007 69 Male 97 lb 7/9/2007 Physician Singapore
Primary
Secondary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 7/11/2007 Physician Poland
Primary
Secondary
Concomitant
Acute Prerenal Failure Other Serious 11/21/2005 56 Male 7/24/2007 Physician Poland
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 11/24/2005 51 Female 7/25/2007 Physician India
Primary
Secondary
Tooth Extraction Other Serious 1/1/2005 Male 7/25/2007 Physician Belgium
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Male 7/25/2007 Physician Belgium
Primary
Secondary
Concomitant
Delirium Life Threatening 8/19/2007 69 Female 104 lb 9/17/2007 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 1/15/2007 71 Male 10/22/2007 Physician Poland
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2005 57 Female 11/2/2007 Physician Switzerland
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 9/27/2007 55 Female 132 lb 11/15/2007 Physician Japan
Primary
Concomitant
Gastroenteritis Hospitalization 12/17/2006 54 Male 108 lb 11/16/2007 Physician Singapore
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 9/25/2007 55 Female 132 lb 12/3/2007 Physician Japan
Primary
Concomitant
Intestinal Ischaemia Life Threatening 6/26/2006 62 Female 12/4/2007 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 9/25/2007 55 Female 132 lb 12/5/2007 Physician Japan
Primary
Concomitant
Pulmonary Embolism Life Threatening 9/25/2007 55 Female 132 lb 12/10/2007 Physician Japan
Primary
Concomitant
Pulmonary Embolism Life Threatening 9/25/2007 55 Female 132 lb 12/17/2007 Physician Japan
Primary
Concomitant
Leukaemia Hospitalization 12/11/2007 60 Female 12/21/2007 Physician Japan
Primary
Secondary
Pulmonary Alveolar Haemorrhage Disability 1/3/2007 64 Male 157 lb 2/11/2008 Physician Japan
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Disability 1/3/2007 64 Male 157 lb 2/14/2008 Physician Japan
Primary
Concomitant
Leukaemia Hospitalization 12/11/2007 60 Female 2/14/2008 Physician Japan
Primary
Secondary
Stomatitis Hospitalization 1/15/2007 71 Male 2/18/2008 Physician Poland
Primary
Secondary
Concomitant
Stomatitis Other Serious 1/15/2007 71 Male 2/26/2008 Physician Poland
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6/26/2003 49 Female 143 lb 3/3/2008 Physician Korea, Republic Of
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 48 Female 4/25/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 48 Female 5/12/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Folliculitis Other Serious 8/17/2007 49 Female 100 lb 6/10/2008 Pharmacist Taiwan, Province Of China
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/12/2008 67 Female 7/28/2008 Physician Italy
Primary
Concomitant
Deafness Disability 7/1/2008 62 Male 7/31/2008 Physician China
Primary
Concomitant
Deafness Disability 7/1/2008 62 Male 8/13/2008 Physician China
Primary
Concomitant
Sepsis Other Serious 1/1/2005 57 Female 9/11/2008 Physician Switzerland
Primary
Secondary
Concomitant

Drug Data