Cisplatin combined with Herceptin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oral Candidiasis Hospitalization 12/28/2005 69 Male 139 lb 1/25/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Haematemesis Death 3/17/2006 50 Male 3/31/2006 Physician Russian Federation
Primary
Secondary
Haematemesis Death 3/17/2006 50 Male 4/4/2006 Other Health Professional Russian Federation
Primary
Secondary
Paraesthesia Disability 2/1/2006 56 Female 5/4/2006 Physician Spain
Primary
Secondary
Concomitant
Paraesthesia Disability 3/1/2006 56 Female 5/22/2006 Physician Spain
Primary
Secondary
Concomitant
Paraesthesia Disability 3/1/2006 56 Female 6/2/2006 Physician Spain
Primary
Secondary
Concomitant
Paraesthesia Disability 3/1/2006 56 Female 7/13/2006 Physician Spain
Primary
Concomitant
Pyrexia Hospitalization 8/6/2005 42 Female 203 lb 6/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/31/2006 51 Male 101 lb 10/2/2006 Physician China
Primary
Secondary
Gastric Perforation Life Threatening 9/21/2006 52 Male 188 lb 10/4/2006 Physician Korea, Republic Of
Primary
Secondary
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Pneumoperitoneum Life Threatening 9/21/2006 52 Male 10/4/2006 Other Health Professional Korea, Republic Of
Primary
Secondary
Gastric Perforation Life Threatening 9/21/2006 52 Male 188 lb 10/23/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Mass Life Threatening 9/21/2006 52 Male 188 lb 10/17/2006 Other Health Professional Korea, Republic Of
Primary
Secondary
Metastases To Liver Life Threatening 9/21/2006 52 Male 188 lb 10/25/2006 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/18/2006 54 Female 100 lb 11/13/2006 Physician Japan
Primary
Secondary
Vomiting Hospitalization 10/22/2006 54 Female 100 lb 11/21/2006 Physician Japan
Primary
Secondary
Concomitant
Po2 Increased Hospitalization 1/1/2006 50 Female 11/15/2006 Physician Japan
Primary
Secondary
Vomiting Hospitalization 10/26/2006 54 Female 100 lb 11/15/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/26/2006 54 Female 100 lb 11/22/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 77 lb 1/5/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/26/2006 54 Female 100 lb 1/3/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/26/2006 54 Female 100 lb 1/5/2007 Physician Japan
Primary
Secondary
Concomitant
Gout Hospitalization 1/8/2007 71 Male 143 lb 1/24/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/18/2006 54 Female 100 lb 1/24/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/8/2007 71 Male 143 lb 3/14/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/8/2007 71 Male 143 lb 3/21/2007 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 3/28/2007 Male 5/10/2007 Physician United Kingdom
Primary
Secondary
Escherichia Urinary Tract Infection Hospitalization 3/28/2007 Male 5/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting 7/6/2007 49 Male 10/11/2007 Consumer United States
Primary
Concomitant
Fibrosis Other Serious 47 Female 1/9/2008 Physician United Kingdom
Primary
Concomitant
Fibrosis Other Serious 47 Female 1/16/2008 Physician United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2007 58 Female 1/18/2008 Consumer United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Death 2/22/2008 Consumer United Kingdom
Primary
Secondary
Ventricular Extrasystoles Other Serious 12/1/2007 58 Female 2/28/2008 Consumer United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Death 2/29/2008 Consumer United Kingdom
Primary
Secondary
Vasculitis Hospitalization 7/22/2008 41 Female 8/13/2008 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Vasculitis Hospitalization 7/22/2008 Female 8/18/2008 Consumer Taiwan, Province Of China
Primary
Secondary
Concomitant
Vasculitis Hospitalization 7/22/2008 Female 8/25/2008 Consumer Taiwan, Province Of China
Primary
Secondary
Concomitant
Blood Amylase Increased Other Serious Female 10/2/2008 Consumer Japan
Primary
Secondary
Concomitant
Dementia Other Serious Female 10/22/2008 Physician Germany
Primary
Secondary
Carpal Tunnel Syndrome Other Serious Female 1/9/2009 Physician United Kingdom
Primary
Concomitant
Carpal Tunnel Syndrome Disability 12/9/2008 Female 1/20/2009 Consumer United Kingdom
Primary
Concomitant
Acute Myeloid Leukaemia Life Threatening 10/1/2008 44 Female 1/27/2009 Physician France
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 44 Female 2/2/2009 Physician France
Primary
Secondary
Concomitant
Colitis Hospitalization 3/10/2009 Consumer United States
Primary
Secondary
Metastases To Central Nervous System Other Serious 7/1/2002 38 Female 5/18/2009 Consumer United Kingdom
Primary
Secondary
Vomiting Other Serious 1/1/2003 Female 162 lb 2/9/2010 Physician United States
Primary
Secondary
Concomitant
Cerebral Infarction Death Male 6/30/2010 Physician Germany
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 5/20/2010 39 Male 207 lb 7/29/2010 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/27/2010 35 Female 137 lb 8/27/2010 Physician Germany
Primary
Concomitant
Death Death Male 10/15/2010 Physician Poland
Primary
Concomitant
Disease Progression Death 43 Male 10/27/2010 Consumer Lebanon
Primary
Concomitant
Cardiac Arrest Death 9/1/2010 50 Female 11/12/2010 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2003 53 Female 162 lb 12/23/2010 Physician United States
Primary
Secondary
Concomitant
Meningioma Other Serious 1/1/2003 53 Female 162 lb 2/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Injection Site Extravasation Other Serious Female 2/24/2011 Other Health Professional France
Primary
Secondary
Death Death Male 3/7/2011 Physician Australia
Primary
Secondary
Concomitant
Infection Other Serious 1/1/2003 53 Female 162 lb 3/23/2011 Physician United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Other Serious 1/1/2003 53 Female 162 lb 4/5/2011 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2003 53 Female 162 lb 5/30/2011 Lawyer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 2/17/2011 70 Female 123 lb 6/6/2011 Physician Japan
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious Female 162 lb 6/10/2011 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 4/10/2011 69 Female 115 lb 6/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 4/8/2011 39 Female 97 lb 6/16/2011 Consumer China
Primary
Concomitant
Infection Hospitalization 4/10/2011 69 Female 115 lb 6/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Aortic Arteriosclerosis Other Serious Female 162 lb 6/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/13/2011 64 Female 123 lb 8/1/2011 Physician Japan
Primary
Secondary
Pancytopenia Death 7/31/2011 74 Male 8/16/2011 Consumer Japan
Primary
Secondary
Anaemia Other Serious 50 Male 8/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 50 Male 9/9/2011 Other Health Professional Japan
Primary
Secondary
Arteriosclerosis Other Serious 7/27/2011 74 Male 106 lb 9/13/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Death 7/31/2011 74 Male 106 lb 9/14/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 55 Male 9/21/2011 Physician Poland
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 6/7/2011 56 Male 172 lb 10/4/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Chest Pain Other Serious 8/21/2011 47 Female 146 lb 11/8/2011 Physician United States
Primary
Concomitant
Infection Hospitalization 2/15/2005 17 11/21/2011 United States
Primary
Secondary
Convulsion Life Threatening 6/14/2005 20 11/21/2011 United States
Primary
Secondary
Cancer Pain Death 76 Male 11/24/2011 Japan
Primary
Secondary
Neutrophil Count Decreased Life Threatening 10/25/2011 77 Male 97 lb 11/29/2011 Physician Japan
Primary
Secondary
Concomitant
Trousseau's Syndrome Hospitalization 60 Male 12/14/2011 Physician Japan
Primary
Secondary
Upper Gastrointestinal Haemorrhage Hospitalization 4/9/2011 48 Male 187 lb 12/22/2011 Physician Germany
Primary
Concomitant
Disease Progression Hospitalization 76 Male 12/28/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 12/9/2011 60 1/2/2012 Physician Japan
Primary
Secondary
Cerebral Infarction Other Serious 12/9/2011 60 Male 137 lb 1/24/2012 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 1/13/2012 49 Male 176 lb 1/25/2012 Germany
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 1/27/2012 Other Health Professional Korea, Republic Of
Primary
Secondary
Activities Of Daily Living Impaired Hospitalization 1/29/2012 68 Male 121 lb 2/9/2012 Korea, Republic Of
Primary
Secondary
Dehydration Hospitalization 2/1/2012 71 Male 2/14/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 11/21/2004 16 2/16/2012 United States
Primary
Secondary
Diarrhoea Hospitalization 2/1/2012 71 Male 2/20/2012 Canada
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 12/9/2011 60 Male 137 lb 2/22/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Fungal Death 1/29/2012 68 Male 121 lb 2/27/2012 Korea, Republic Of
Primary
Secondary
Decreased Appetite Death 7/27/2011 74 Male 106 lb 3/1/2012 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 1/26/2012 65 Male 163 lb 3/7/2012 Physician Austria
Primary
Concomitant
Hypomagnesaemia Other Serious 70 Female 3/12/2012 Physician Japan
Primary
Secondary
Fatigue Death 1/29/2012 68 Male 121 lb 3/25/2012 Korea, Republic Of
Primary
Secondary
Hypokalaemia Hospitalization 3/4/2012 61 Male 185 lb 3/29/2012 Physician Germany
Primary
Secondary
Sepsis Death 85 Male 3/29/2012 Physician Brazil
Primary
Concomitant
Respiratory Failure Death 2/28/2012 46 Male 4/3/2012 Physician Japan
Primary
Secondary
Concomitant
Amylase Increased Other Serious 1/1/2012 67 Male 4/10/2012 Pharmacist Japan
Primary
Secondary
Constipation Hospitalization 1/1/2011 59 Male 143 lb 4/13/2012 Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious 3/17/2012 77 Female 4/17/2012 Physician France
Primary
Secondary
Concomitant
Ileus Hospitalization 4/11/2012 68 Female 104 lb 4/26/2012 Physician Korea, Republic Of
Primary
Secondary
Skin Infection Hospitalization 4/9/2011 48 Male 187 lb 4/26/2012 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 4/11/2012 68 Female 104 lb 4/26/2012 Physician Korea, Republic Of
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 55 Male 4/26/2012 Japan
Primary
Secondary
Metastatic Gastric Cancer Hospitalization 2/28/2012 59 Male 106 lb 4/27/2012 Physician Japan
Primary
Secondary
Concomitant
Enteritis Other Serious 3/28/2012 76 Male 163 lb 4/27/2012 Physician Spain
Primary
Secondary
Vomiting Hospitalization 4/11/2012 68 Female 104 lb 4/30/2012 Korea, Republic Of
Primary
Secondary
Dilatation Ventricular Other Serious 9/14/2011 72 Male 4/30/2012 Other Health Professional Italy
Primary
Concomitant
Neutropenia Hospitalization 3/17/2012 77 Female 5/1/2012 Other Health Professional France
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 55 Male 5/7/2012 Japan
Primary
Secondary
Vomiting Hospitalization 4/11/2012 68 Female 100 lb 5/8/2012 Korea, Republic Of
Primary
Secondary
Diarrhoea Hospitalization 4/11/2012 68 Female 104 lb 5/9/2012 Physician Korea, Republic Of
Primary
Secondary
Fatigue Hospitalization 1/29/2012 68 Male 121 lb 5/10/2012 Physician Korea, Republic Of
Primary
Secondary
Diarrhoea Hospitalization 2/1/2012 71 Male 5/24/2012 Physician Canada
Primary
Secondary
Concomitant
Enteritis Other Serious 3/28/2012 76 Male 163 lb 5/28/2012 Spain
Primary
Secondary
Blood Creatinine Increased Other Serious 8/29/2011 54 Male 5/28/2012 Physician Japan
Primary
Secondary
Blood Creatinine Increased Other Serious 8/29/2011 54 Male 5/30/2012 Physician Japan
Primary
Secondary
Left Ventricular Dysfunction Hospitalization 5/16/2012 42 Male 6/4/2012 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/5/2012 Italy
Primary
Secondary
Ejection Fraction Decreased Hospitalization 5/23/2012 77 Male 154 lb 6/7/2012 Italy
Primary
Secondary
Ejection Fraction Decreased Hospitalization 5/23/2012 77 Male 154 lb 6/8/2012 Italy
Primary
Secondary
N-terminal Prohormone Brain Natriuretic Peptide Increased Hospitalization 5/23/2012 77 Male 154 lb 6/8/2012 Physician Italy
Primary
Secondary
Pulmonary Artery Thrombosis Other Serious 55 Male 6/8/2012 Other Health Professional Japan
Primary
Secondary
Vomiting Hospitalization 4/11/2012 68 Female 101 lb 6/8/2012 Korea, Republic Of
Primary
Secondary
C-reactive Protein Increased Other Serious 1/31/2012 61 Male 90 lb 6/11/2012 Physician Japan
Primary
Concomitant
Viral Infection Hospitalization 4/11/2012 68 Female 101 lb 6/11/2012 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 5/23/2012 77 Male 154 lb 6/12/2012 Italy
Primary
Secondary
Diarrhoea Hospitalization 4/11/2012 68 Female 101 lb 6/13/2012 Korea, Republic Of
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 3/17/2012 77 Female 6/15/2012 Physician France
Primary
Secondary
Concomitant
Neutropenic Colitis Hospitalization 3/17/2012 77 Female 6/22/2012 Other Health Professional France
Primary
Secondary
Concomitant
Nausea Other Serious 6/8/2012 30 Female 6/27/2012 Physician Finland
Primary
Concomitant
N-terminal Prohormone Brain Natriuretic Peptide Increased Hospitalization 5/23/2012 77 Male 154 lb 7/13/2012 Physician Italy
Primary
Secondary
Febrile Neutropenia Hospitalization 6/29/2012 69 Female 106 lb 7/16/2012 Physician Korea, Democratic People's Republic Of
Primary
Secondary
Venous Thrombosis Limb Hospitalization 1/13/2012 48 Male 176 lb 7/18/2012 Physician Germany
Primary
Secondary
Concomitant
Venous Thrombosis Limb Hospitalization 1/13/2012 48 Male 176 lb 7/20/2012 Physician Germany
Primary
Secondary
Concomitant
Venous Thrombosis Limb Hospitalization 1/13/2012 49 Male 176 lb 7/24/2012 Physician Germany
Primary
Secondary
Rash Other Serious 82 7/30/2012 Physician Japan
Primary
Secondary
Concomitant
N-terminal Prohormone Brain Natriuretic Peptide Increased Hospitalization 5/23/2012 77 Male 154 lb 7/30/2012 Physician Italy
Primary
Secondary
Mucosal Inflammation Hospitalization 6/29/2012 69 Female 106 lb 7/31/2012 Physician Korea, Republic Of
Primary
Secondary
Febrile Neutropenia Hospitalization 6/29/2012 69 Female 106 lb 8/1/2012 Physician Korea, Republic Of
Primary
Secondary
Neutropenia Other Serious 4/9/2011 48 Male 187 lb 8/2/2012 Physician Germany
Primary
Concomitant
Enteritis Other Serious 3/28/2012 76 Male 163 lb 8/8/2012 Physician Spain
Primary
Secondary
Concomitant
Vomiting Other Serious 8/14/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/29/2012 69 Female 106 lb 8/15/2012 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/29/2012 68 Male 121 lb 8/16/2012 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Metastases To Breast Other Serious 7/1/2012 30 Female 128 lb 8/17/2012 Consumer China
Primary
Secondary
Concomitant

Drug Data