Chlorambucil combined with Prednisolone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Viiith Nerve Injury Hospitalization 2/1/2004 Male 1/27/2006 Physician United Kingdom
Primary
Concomitant
T-cell Lymphoma Death 66 Male 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Death 6/15/2006 Austria
Primary
Secondary
Simple Partial Seizures Death 6/4/2006 89 Male 7/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 7/1/1999 54 Male 10/13/2006
Primary
Secondary
Liver Disorder Hospitalization 10/1/2005 66 Male 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
T-cell Lymphoma Other Serious 7/1/2005 66 Male 5/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 75 Male 8/30/2007 Physician United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 7/1/2003 Female 128 lb 10/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Retinitis Viral Other Serious 67 Female 11/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/3/2008 Male 165 lb 3/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Retinitis Viral Other Serious 67 Female 3/6/2008 United Kingdom
Primary
Secondary
Respiratory Distress Other Serious 5/18/2007 Female 106 lb 3/17/2008 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Other Serious 67 Female 3/20/2008 United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 1/3/2008 Male 165 lb 5/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 2/13/2008 Female 132 lb 5/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/3/2008 Male 165 lb 5/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2001 58 Male 6/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mood Disorder Due To A General Medical Condition Hospitalization 2/21/2008 Female 176 lb 7/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 71 Female 8/4/2008 Consumer Korea, Republic Of
Primary
Secondary
Mood Disorder Due To A General Medical Condition Hospitalization 2/21/2008 Female 176 lb 9/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Disability 5/2/2007 67 Female 10/9/2008 Physician Canada
Primary
Secondary
Neoplasm Malignant Death 4/9/2008 Male 10/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2008 74 Female 10/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/28/2008 74 Female 10/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/15/2008 United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 10/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Death 4/9/2008 Male 10/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 10/31/2008 Consumer United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 74 Female 11/7/2008 United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/7/2008 United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/31/2008 United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/18/2008 Consumer United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Death 4/9/2008 Male 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 74 Female 11/18/2008 United Kingdom
Primary
Secondary
Concomitant
Neoplasm Malignant Death 4/9/2008 Male 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Retinal Haemorrhage Death 1/1/2003 59 Male 3/17/2008 Physician United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Sudden Death Death 12/18/2008 Male 1/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 9/1/2002 Female 3/26/2009 Norway
Primary
Concomitant
Dyspepsia Other Serious 4/15/2009 Consumer United Kingdom
Primary
Secondary
Stomatitis Other Serious 4/15/2009 Consumer United Kingdom
Primary
Secondary
Pancytopenia Other Serious 1/1/2008 74 Female 4/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Viral Hospitalization 4/3/2009 Female 5/12/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Tract Infection Viral Hospitalization 4/3/2009 Female 5/20/2009 Physician United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2006 69 Male 6/26/2009 Other Health Professional Czech Republic
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2006 69 Male 6/30/2009 Other Health Professional Czech Republic
Primary
Secondary
Pneumonia Other Serious 52 Male 8/13/2009 Consumer Poland
Primary
Concomitant
Respiratory Tract Infection Viral Hospitalization 4/3/2009 Female 8/18/2009 Physician United Kingdom
Primary
Concomitant
Skin Discolouration Other Serious 60 Female 8/18/2009 Physician United Kingdom
Primary
Concomitant
Skin Discolouration Other Serious 60 Female 9/10/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Tract Infection Viral Hospitalization 4/3/2009 Female 9/21/2009 Physician United Kingdom
Primary
Concomitant
Death Death 9/17/2008 Female 10/8/2009 Physician United Kingdom
Primary
Secondary
Respiratory Tract Infection Viral Hospitalization 4/3/2009 Female 10/19/2009 Physician United Kingdom
Primary
Concomitant
Non-hodgkin's Lymphoma Death 9/17/2008 Female 10/29/2009 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 11/16/2009 Male 161 lb 12/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Nocardiosis Death 69 Female 11/24/2009 Korea, Republic Of
Primary
Secondary
Jaundice Cholestatic Other Serious 82 Male 2/12/2010 Consumer United Kingdom
Primary
Concomitant
Cardiomyopathy Disability 12/1/2006 Male 2/23/2010 Physician United Kingdom
Primary
Secondary
Cardiomyopathy Other Serious 12/28/2006 Male 3/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Death 10/18/2009 Female 154 lb 3/30/2010 Physician United Kingdom
Primary
Secondary
Weight Decreased Other Serious 69 Male 4/2/2010 United Kingdom
Primary
Secondary
Erythema Infectiosum Other Serious 1/1/2009 69 Male 4/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Pleural Effusion Hospitalization 3/20/2010 65 Female 165 lb 4/13/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 10/27/2009 29 Female 123 lb 4/14/2010 Physician United Kingdom
Primary
Concomitant
Skin Disorder Other Serious 6/1/2009 86 Male 143 lb 4/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 69 Male 4/8/2010 United Kingdom
Primary
Secondary
Non-hodgkin's Lymphoma Death 9/20/2009 84 Female 154 lb 4/23/2010 Physician United Kingdom
Primary
Secondary
Leukoencephalopathy Death 2/1/2009 71 Female 110 lb 5/13/2010 Physician Netherlands
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 1/29/2010 82 Male 154 lb 7/7/2010 Consumer United Kingdom
Primary
Concomitant
Pneumonia Primary Atypical Hospitalization 7/20/2010 57 Female 159 lb 9/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 7/20/2010 57 Female 159 lb 9/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/20/2010 57 Female 159 lb 9/24/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/20/2010 57 Female 159 lb 10/11/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Disability 58 Female 10/29/2010 Consumer United Kingdom
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 51 Female 2/28/2011 Physician Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 51 Female 2/28/2011 Physician Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 61 Female 2/28/2011 Physician Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 53 Male 2/28/2011 Other Health Professional Australia
Primary
Secondary
Neutropenic Sepsis Hospitalization 7/13/2009 77 Male 8/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Infective Exacerbation Of Chronic Obstructive Airways Disease Hospitalization 1/18/2011 68 Male 8/9/2011 Physician Germany
Primary
Secondary
Concomitant
Gaze Palsy Death 60 Male 9/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 8/16/2011 64 Male 10/14/2011 Physician Denmark
Primary
Secondary
Concomitant
Infertility Other Serious 12 Male 10/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Paraesthesia Death 8/16/2011 64 Male 12/9/2011 Physician Denmark
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 8/16/2011 64 Male 12/16/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 59 Male 1/31/2012 Other Health Professional Latvia
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 8/16/2011 64 Male 2/22/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Sepsis Death 4/9/2012 Other Health Professional United Kingdom
Primary
Secondary
Rectal Cancer Death 4/9/2012 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Death 4/10/2012 Other Health Professional United Kingdom
Primary
Secondary
Convulsion Other Serious 4/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Mental Disorder Other Serious 4/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 4/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Diffuse Large B-cell Lymphoma Other Serious 4/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Colon Cancer Other Serious 4/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Lymphoproliferative Disorder Other Serious 4/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Basal Cell Carcinoma Other Serious 4/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Colon Cancer Other Serious 4/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Diffuse Large B-cell Lymphoma Other Serious 4/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Neutropenia Other Serious 4/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Hospitalization 2/8/2012 70 Female 202 lb 5/14/2012 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 2/8/2012 70 Female 202 lb 5/17/2012 United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 8/16/2011 64 Male 6/7/2012 Consumer Denmark
Primary
Secondary
Concomitant
Dehydration Hospitalization 2/8/2012 70 Female 202 lb 6/7/2012 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 77 Male 7/11/2012 Physician France
Primary
Concomitant
Paraesthesia Hospitalization 8/16/2011 64 Male 7/19/2012 Consumer Denmark
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/28/2012 76 Male 165 lb 7/23/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/28/2012 76 Male 165 lb 8/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcus Test Positive Hospitalization 78 Male 3/7/2012 Physician Nz
Primary
Secondary
Tremor Hospitalization 8/16/2011 64 Male 10/1/2012 Other Health Professional Dk
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 8/16/2011 64 Male 3/14/2013 Physician Dk
Primary
Secondary
Concomitant
Pneumonia Klebsiella Hospitalization 6/16/2011 55 Male 6/7/2013 Other Health Professional Nl
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/2/2012 76 Male 8/16/2012 Gb
Primary
Secondary
Concomitant
Staphylococcus Test Positive Hospitalization 5/28/2012 54 Female 220 lb 8/8/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 6/28/2012 76 Male 165 lb 9/20/2012 Physician Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/10/2012 52 Male 146 lb 9/7/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious Female 10/4/2012 Physician Us
Primary
Concomitant
Weight Decreased Hospitalization Male 10/26/2012 Physician Us
Primary
Concomitant
Hodgkin's Disease Other Serious 57 Male 10/10/2012 Other Health Professional Fr
Primary
Secondary
Febrile Neutropenia Hospitalization 12/12/2012 84 Male 1/2/2013 Physician Gb
Primary
Secondary
Concomitant
Bacteraemia Hospitalization 12/20/2012 70 Male 165 lb 12/20/2012 Other Health Professional De
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/20/2012 79 Female 188 lb 12/20/2012 Other Health Professional De
Primary
Secondary
Concomitant
Productive Cough Hospitalization 3/7/2013 69 Male 167 lb 3/26/2013 Gb
Primary
Secondary
Concomitant
Lung Infection Hospitalization 4/26/2013 68 Male 229 lb 6/5/2013 Physician Gb
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/10/2013 74 Male 216 lb 7/1/2013 Physician Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/29/2013 78 Male 170 lb 7/23/2013 Physician Gb
Primary
Secondary
Concomitant
Rash Hospitalization 7/8/2013 81 Male 176 lb 8/30/2013 Physician Gb
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/9/2013 74 Male 7/22/2013 Physician Gb
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/21/2013 67 Female 136 lb 8/30/2013 Physician Gb
Primary
Secondary
Concomitant
Hepatitis B Hospitalization 87 Female 9/13/2013 Other Health Professional Country Not Specified
Primary
Secondary
Hepatitis B Other Serious 8/2006 87 Female 9/16/2013 Other Health Professional Fr
Primary
Secondary
Chronic Lymphocytic Leukaemia Hospitalization 66 Female 9/17/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Infection Hospitalization 9/19/2013 68 Female 142 lb 10/8/2013 Physician Gb
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 10/8/2013 80 Male 164 lb 10/18/2013 Physician Gb
Primary
Secondary
Concomitant
Embolism Hospitalization 10/22/2013 75 Male 237 lb 11/4/2013 Physician Gb
Primary
Secondary
Concomitant

Drug Data