Chlorambucil combined with Ofatumumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Tract Infection Hospitalization 3/3/2009 Male 206 lb 4/2/2009 Physician Ireland
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 3/3/2009 Male 206 lb 6/4/2009 Physician Ireland
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/5/2009 Male 207 lb 6/23/2009 Physician Russian Federation
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/20/2009 Male 203 lb 10/2/2009 Physician Belgium
Primary
Secondary
Neutropenia Other Serious 6/5/2009 Male 207 lb 10/2/2009 Physician Russian Federation
Primary
Secondary
Concomitant
Renal Colic Hospitalization 9/23/2009 Male 148 lb 10/2/2009 Physician United Kingdom
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 11/12/2009 Male 181 lb 11/19/2009 Physician Germany
Primary
Secondary
Pneumonia Life Threatening 12/17/2009 Male 159 lb 12/23/2009 Physician Germany
Primary
Secondary
Pneumonia Hospitalization 12/22/2009 Male 181 lb 1/6/2010 Physician United Kingdom
Primary
Secondary
Pneumonia Hospitalization 12/22/2009 Male 181 lb 1/7/2010 Physician United Kingdom
Primary
Secondary
Pneumonia Hospitalization 12/22/2009 Male 181 lb 1/19/2010 Physician United Kingdom
Primary
Secondary
Neutropenia Life Threatening 1/14/2010 Female 209 lb 1/21/2010 Physician Poland
Primary
Secondary
Pneumonia Life Threatening 12/17/2009 Male 159 lb 1/28/2010 Physician Germany
Primary
Secondary
Pneumonia Life Threatening 12/17/2009 Male 159 lb 1/29/2010 Physician Germany
Primary
Secondary
Neutropenia Life Threatening 1/14/2010 Female 209 lb 2/3/2010 Physician Poland
Primary
Secondary
Pneumonia Hospitalization 12/22/2009 Male 181 lb 2/5/2010 Physician United Kingdom
Primary
Secondary
Sepsis Hospitalization 9/20/2009 73 Male 203 lb 4/9/2010 Physician Belgium
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/20/2009 73 Male 203 lb 4/9/2010 Physician Belgium
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/22/2009 80 Male 181 lb 4/16/2010 Physician United Kingdom
Primary
Secondary
Tonsillar Hypertrophy Disability 60 Female 4/22/2010 Consumer France
Primary
Concomitant
Pneumonia Hospitalization 4/3/2010 76 Male 143 lb 4/22/2010 Physician Italy
Primary
Secondary
Dyspnoea Hospitalization 4/26/2010 72 Male 168 lb 5/6/2010 Physician Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/26/2010 72 Male 168 lb 5/24/2010 Physician Germany
Primary
Secondary
Concomitant
Acute Pulmonary Oedema Life Threatening 5/19/2010 74 Male 163 lb 5/27/2010 Physician Italy
Primary
Secondary
Acute Pulmonary Oedema Life Threatening 5/19/2010 74 Male 163 lb 5/28/2010 Physician Italy
Primary
Secondary
Respiratory Failure Life Threatening 4/12/2010 76 Male 143 lb 5/28/2010 Physician Italy
Primary
Secondary
Respiratory Failure Life Threatening 4/12/2010 76 Male 143 lb 5/28/2010 Physician Italy
Primary
Secondary
Headache Hospitalization 6/7/2010 76 Male 173 lb 6/21/2010 Physician Belgium
Primary
Secondary
Febrile Neutropenia Hospitalization 7/30/2009 71 Male 149 lb 6/25/2010 Physician Greece
Primary
Secondary
Concomitant
Renal Colic Hospitalization 9/23/2009 72 Male 148 lb 7/1/2010 Physician United Kingdom
Primary
Secondary
Renal Colic Hospitalization 9/23/2009 72 Male 148 lb 7/1/2010 Physician United Kingdom
Primary
Secondary
Neutropenia Other Serious 8/10/2010 62 Male 176 lb 8/19/2010 Physician Spain
Primary
Secondary
Concomitant
Neutropenia Other Serious 8/10/2010 62 Male 176 lb 8/27/2010 Physician Spain
Primary
Secondary
Concomitant
Neutropenia Other Serious 8/10/2010 62 Male 176 lb 8/30/2010 Physician Spain
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/30/2009 71 Male 149 lb 10/13/2010 Physician Greece
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/30/2009 71 Male 149 lb 11/1/2010 Physician Greece
Primary
Secondary
Concomitant
Tremor Hospitalization 10/26/2010 82 Male 175 lb 11/3/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vertigo Labyrinthine Other Serious 10/31/2010 73 Male 152 lb 11/17/2010 Physician Poland
Primary
Secondary
Vertigo Labyrinthine Other Serious 10/31/2010 73 Male 152 lb 11/17/2010 Physician Poland
Primary
Secondary
Tremor Hospitalization 10/26/2010 82 Male 175 lb 11/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 10/26/2010 82 Male 175 lb 11/23/2010 Physician United Kingdom
Primary
Secondary
Tremor Hospitalization 11/24/2010 82 Male 175 lb 11/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Cognitive Disorder Other Serious 11/24/2010 82 Male 175 lb 12/1/2010 Physician United Kingdom
Primary
Secondary
Respiratory Failure Life Threatening 4/12/2010 76 Male 143 lb 12/2/2010 Physician Italy
Primary
Secondary
Respiratory Failure Life Threatening 4/12/2010 76 Male 143 lb 12/2/2010 Physician Italy
Primary
Secondary
Vertigo Hospitalization 10/31/2010 73 Male 152 lb 12/16/2010 Physician Poland
Primary
Secondary
Vertigo Labyrinthine Other Serious 10/31/2010 73 Male 11/26/2010 Poland
Primary
Secondary
Tremor Hospitalization 10/26/2010 82 Male 12/1/2010 United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 11/12/2009 79 Male 181 lb 12/29/2010 Physician Germany
Primary
Secondary
Vertigo Labyrinthine Other Serious 10/31/2010 73 Male 12/14/2010 Physician Poland
Primary
Secondary
Concomitant
Bilirubin Conjugated Increased Hospitalization 11/20/2009 79 Male 1/11/2011 Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 1/22/2011 80 Female 139 lb 2/3/2011 Physician United Kingdom
Primary
Secondary
Respiratory Failure Life Threatening 5/19/2010 74 Male 163 lb 2/4/2011 Physician Italy
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/22/2011 80 Female 139 lb 2/4/2011 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 1/22/2011 80 Female 139 lb 2/24/2011 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 1/22/2011 80 Female 139 lb 2/24/2011 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 2/21/2011 81 Male 136 lb 3/3/2011 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 2/21/2011 81 Male 136 lb 3/17/2011 Physician United Kingdom
Primary
Secondary
Neutropenic Sepsis Hospitalization 3/7/2011 80 Female 141 lb 3/17/2011 Physician United Kingdom
Primary
Secondary
Myoclonus Other Serious 5/31/2010 72 Male 173 lb 4/1/2011 Physician United Kingdom
Primary
Secondary
Myoclonus Other Serious 5/31/2010 72 Male 173 lb 4/4/2011 Physician United Kingdom
Primary
Secondary
Neutropenic Sepsis Hospitalization 3/7/2011 80 Female 141 lb 4/15/2011 Physician United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 4/26/2010 72 Male 168 lb 4/19/2011 Physician Germany
Primary
Secondary
Myoclonus Other Serious 5/31/2010 72 Male 173 lb 4/19/2011 Physician United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 4/26/2010 72 Male 168 lb 4/19/2011 Physician Germany
Primary
Secondary
Infection Death Male 117 lb 4/21/2011 Physician Poland
Primary
Secondary
Brain Neoplasm Disability 4/15/2011 46 Female 172 lb 4/21/2011 Physician Greece
Primary
Secondary
Infection Death 4/4/2011 83 Male 117 lb 4/22/2011 Physician Poland
Primary
Secondary
Brain Neoplasm Life Threatening 4/15/2011 46 Female 172 lb 4/22/2011 Physician Greece
Primary
Secondary
Infection Death 4/4/2011 83 Male 117 lb 4/22/2011 Physician Poland
Primary
Secondary
Cardiac Failure Death 4/15/2011 62 Female 168 lb 4/26/2011 Physician Germany
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Death 4/15/2011 62 Female 168 lb 4/26/2011 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Death 72 Male 4/28/2011 Other Health Professional Germany
Primary
Secondary
Acute Respiratory Distress Syndrome Hospitalization 4/9/2011 80 Male 4/26/2011 Other Health Professional Belgium
Primary
Secondary
Agranulocytosis Death 4/4/2011 83 Male 117 lb 5/19/2011 Physician Poland
Primary
Secondary
Agranulocytosis Death 4/4/2011 83 Male 117 lb 5/19/2011 Physician Poland
Primary
Secondary
Sepsis Death 4/26/2010 72 Male 168 lb 5/25/2011 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/7/2011 80 Female 141 lb 5/25/2011 Physician United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 4/26/2010 72 Male 168 lb 5/25/2011 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/19/2010 74 Male 128 lb 6/3/2011 Physician Italy
Primary
Secondary
Depression Hospitalization 9/19/2010 74 Male 128 lb 6/3/2011 Physician Italy
Primary
Secondary
Agranulocytosis Hospitalization 4/4/2011 83 Male 117 lb 6/7/2011 Physician Poland
Primary
Secondary
Agranulocytosis Hospitalization 4/4/2011 83 Male 117 lb 6/8/2011 Physician Poland
Primary
Secondary
Depression Hospitalization 9/19/2010 74 Male 128 lb 6/10/2011 Physician Italy
Primary
Secondary
Confusional State Hospitalization 9/19/2010 74 Male 128 lb 6/10/2011 Physician Italy
Primary
Secondary
Glioblastoma Multiforme Disability 4/15/2011 46 Female 172 lb 6/13/2011 Physician Greece
Primary
Secondary
Transfusion Reaction Hospitalization 5/20/2011 66 Female 134 lb 6/15/2011 Physician Germany
Primary
Secondary
Glioblastoma Multiforme Life Threatening 4/15/2011 46 Female 172 lb 6/17/2011 Physician Greece
Primary
Secondary
Transfusion Reaction Hospitalization 5/20/2011 66 Female 134 lb 6/17/2011 Physician Germany
Primary
Secondary
Neutropenic Sepsis Hospitalization 4/4/2011 83 Male 117 lb 6/20/2011 Physician Poland
Primary
Secondary
Neutropenic Sepsis Hospitalization 4/4/2011 83 Male 117 lb 6/20/2011 Physician Poland
Primary
Secondary
Haemolysis Hospitalization 5/20/2011 66 Female 134 lb 8/22/2011 Physician Germany
Primary
Secondary
Haemolysis Hospitalization 5/20/2011 66 Female 134 lb 8/23/2011 Physician Germany
Primary
Secondary
Dizziness Hospitalization 10/26/2010 82 Male 175 lb 9/16/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Life Threatening 9/2/2011 66 Female 134 lb 9/23/2011 Physician Germany
Primary
Secondary
Neutropenia Life Threatening 9/20/2011 66 Female 134 lb 9/23/2011 Physician Germany
Primary
Secondary
Neutropenia Life Threatening 9/20/2011 66 Female 134 lb 10/3/2011 Physician Germany
Primary
Secondary
Hepatic Enzyme Increased Hospitalization 11/1/2011 70 Female 171 lb 11/8/2011 Physician Poland
Primary
Secondary
Febrile Neutropenia Hospitalization 11/9/2011 58 Male 137 lb 11/22/2011 Physician India
Primary
Secondary
Headache Hospitalization 10/26/2010 82 Male 175 lb 11/23/2011 Physician United Kingdom
Primary
Secondary
Hepatic Enzyme Increased Hospitalization 11/1/2011 70 Female 171 lb 12/5/2011 Physician Poland
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/3/2011 69 Female 165 lb 12/14/2011 Physician Sweden
Primary
Secondary
Febrile Neutropenia Hospitalization 12/3/2011 69 Female 165 lb 12/20/2011 Physician Sweden
Primary
Secondary
Bladder Transitional Cell Carcinoma Hospitalization 77 Male 193 lb 12/14/2011 Belgium
Primary
Secondary
Haemophilus Test Positive Hospitalization 12/3/2011 69 Female 1/4/2012 Sweden
Primary
Secondary
Infection Hospitalization 8/28/2011 79 Male 2/17/2012 Other Health Professional Belgium
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/27/2012 70 Female 165 lb 3/15/2012 Physician Sweden
Primary
Secondary
Pneumonitis Other Serious 3/23/2012 82 Male 4/11/2012 Other Health Professional Ireland
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 2/21/2011 81 Male 136 lb 4/30/2012 Physician United Kingdom
Primary
Secondary
Neutropenic Sepsis Hospitalization 2/21/2011 81 Male 136 lb 4/30/2012 Physician United Kingdom
Primary
Secondary
Asthenia Hospitalization 4/8/2009 53 Female 55 lb 11/8/2011 Other Health Professional Belgium
Primary
Secondary
Chronic Obstructive Pulmonary Disease Death 4/15/2011 62 Female 168 lb 7/16/2012 Physician Germany
Primary
Secondary
Concomitant
Hydronephrosis Hospitalization 9/23/2009 72 Male 148 lb 7/17/2012 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 6/28/2012 76 Male 165 lb 7/23/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/28/2012 76 Male 165 lb 8/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/9/2011 58 Male 137 lb 8/3/2012 Physician India
Primary
Secondary
Concomitant
Hydronephrosis Hospitalization 9/23/2009 72 Male 148 lb 8/6/2012 Physician United Kingdom
Primary
Secondary
Extrasystoles Hospitalization 7/5/2012 71 Male 183 lb 8/8/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Life Threatening 4/3/2010 76 Male 143 lb 6/7/2013 It
Primary
Secondary
Vertigo Labyrinthine Hospitalization 10/31/2010 73 Male 152 lb 6/7/2013 Pl
Primary
Secondary
Concomitant
Sepsis Death 72 Male 168 lb 6/7/2013 Other Health Professional De
Primary
Secondary
Concomitant
Hypotension Hospitalization 6/9/2010 80 Male 159 lb 6/6/2013 Gb
Primary
Secondary
Concomitant
No Adverse Event Hospitalization 3/21/2011 83 Male 117 lb Pl
Primary
Secondary
Haemolysis Hospitalization 5/20/2011 66 Female 134 lb 9/28/2012 Physician De
Primary
Secondary
Hepatic Enzyme Increased Hospitalization 11/2/2011 71 Female 171 lb 12/14/2012 Physician Pl
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/17/2011 74 Male 243 lb 5/21/2013 Other Health Professional Be
Primary
Secondary
Serum Ferritin Decreased Hospitalization 2/14/2011 79 Male 141 lb 4/25/2013 Other Health Professional Pl
Primary
Secondary
Concomitant
Septic Shock Hospitalization 4/8/2009 53 Female 55 lb 11/8/2011 Other Health Professional Be
Primary
Secondary
Pyrexia Hospitalization 5/2/2012 76 Male 8/16/2012 Gb
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/7/2011 80 Female 141 lb 8/16/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/7/2011 80 Female 141 lb 5/22/2013 Other Health Professional Gb
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 9/23/2009 73 Male 148 lb 4/23/2013 Physician Gb
Primary
Secondary
Concomitant
Staphylococcus Test Positive Hospitalization 5/28/2012 54 Female 220 lb 8/8/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 6/28/2012 76 Male 165 lb 9/20/2012 Physician Gb
Primary
Secondary
Concomitant
Glioblastoma Multiforme Disability 3/27/2011 46 Female 172 lb 2/13/2013 Physician Gr
Primary
Secondary
Respiratory Failure Hospitalization 4/3/2010 77 Male 143 lb 9/25/2012 Physician It
Primary
Secondary
Chest Pain Hospitalization 11/4/2012 83 Male 136 lb 3/13/2013 Physician Gb
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/12/2012 84 Male 1/2/2013 Physician Gb
Primary
Secondary
Concomitant
Hypoxia Hospitalization 1/7/2013 72 Female 93 lb 1/22/2013 Other Health Professional Jp
Primary
Secondary
Skin Infection Hospitalization 11/23/2012 87 Male 163 lb 2/25/2013 Physician Gb
Primary
Secondary
Concomitant
Syncope Hospitalization 11/7/2009 68 Male 211 lb 4/9/2013 Other Health Professional Us
Primary
Secondary
Lung Infection Hospitalization 4/26/2013 68 Male 229 lb 6/5/2013 Physician Gb
Primary
Secondary
Concomitant
Lung Infection Hospitalization 4/26/2013 68 Male 229 lb 6/7/2013 Gb
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/10/2013 74 Male 216 lb 7/1/2013 Physician Gb
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/12/2013 72 Male 6/28/2013 Other Health Professional Pl
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/29/2013 78 Male 170 lb 7/23/2013 Physician Gb
Primary
Secondary
Concomitant
Rash Hospitalization 7/8/2013 81 Male 176 lb 8/30/2013 Physician Gb
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/9/2013 74 Male 7/22/2013 Physician Gb
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/21/2013 67 Female 136 lb 8/30/2013 Physician Gb
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/4/2012 83 Male 136 lb 8/8/2013 Gb
Primary
Secondary
Concomitant

Drug Data