Therapeutic Response Unexpected With Drug Substitution |
Required Intervention |
6/1/2007 |
|
Male |
|
2/8/2008 |
Physician |
United States |
|
Pulmonary Embolism |
Other Serious |
1/1/2008 |
|
Female |
145 lb |
8/1/2008 |
|
United States |
|
Endocrine Ophthalmopathy |
Other Serious |
7/1/2008 |
|
Female |
242 lb |
9/15/2008 |
Physician |
United States |
|
Gastrooesophageal Reflux Disease |
|
|
53 |
Female |
|
10/10/2008 |
Consumer |
United States |
|
Transient Ischaemic Attack |
Hospitalization |
9/1/2007 |
|
Female |
150 lb |
10/27/2008 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Peripheral Coldness |
|
|
|
Male |
|
11/13/2008 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
International Normalised Ratio Decreased |
Other Serious |
1/1/2008 |
72 |
Female |
150 lb |
12/8/2008 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
International Normalised Ratio Decreased |
Other Serious |
1/1/2008 |
72 |
Female |
150 lb |
12/10/2008 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Pneumonia |
|
12/1/2007 |
|
Female |
|
12/11/2008 |
Consumer |
United States |
|
Transient Ischaemic Attack |
Hospitalization |
9/1/2007 |
|
Female |
150 lb |
12/16/2008 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Swelling Face |
|
|
69 |
Male |
230 lb |
12/17/2008 |
Consumer |
United States |
|
Abdominal Pain Upper |
|
12/18/2008 |
74 |
Female |
141 lb |
1/15/2009 |
Consumer |
United States |
|
Tension |
|
|
79 |
Female |
|
2/9/2009 |
Consumer |
United States |
|
Urticaria |
Life Threatening |
12/2/2008 |
72 |
Female |
262 lb |
2/13/2009 |
Physician |
|
Primary |
|
Secondary |
|
Concomitant |
|
|
Upper Gastrointestinal Haemorrhage |
Hospitalization |
2/28/2009 |
70 |
Male |
201 lb |
3/4/2009 |
Pharmacist |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vision Blurred |
|
11/1/2008 |
|
Male |
205 lb |
3/14/2009 |
Physician |
United States |
|
Ulcer |
Other Serious |
3/2/2004 |
|
Female |
|
3/25/2009 |
Consumer |
United States |
|
Joint Effusion |
|
6/9/2008 |
84 |
Female |
|
4/21/2009 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Rash Pruritic |
|
5/27/2008 |
55 |
Female |
162 lb |
5/15/2009 |
Other Health Professional |
United States |
|
Middle Insomnia |
|
4/1/2009 |
|
Male |
150 lb |
5/27/2009 |
|
United States |
|
Rheumatoid Nodule |
Other Serious |
4/22/2009 |
|
Female |
112 lb |
6/12/2009 |
Other Health Professional |
United States |
|
Transient Ischaemic Attack |
Other Serious |
|
78 |
Female |
|
6/22/2009 |
Consumer |
United States |
|
Transient Ischaemic Attack |
Other Serious |
|
78 |
Female |
|
6/25/2009 |
Consumer |
United States |
|
Ulcer |
Other Serious |
1/1/2004 |
|
Female |
|
7/1/2009 |
Consumer |
United States |
|
Vomiting |
Other Serious |
6/1/2009 |
82 |
Male |
|
7/6/2009 |
Other Health Professional |
United States |
|
Vision Blurred |
|
5/28/2009 |
62 |
Female |
|
8/10/2009 |
Consumer |
United States |
|
Burning Sensation |
|
|
|
Male |
|
8/22/2009 |
|
United States |
|
Skin Burning Sensation |
|
4/11/2009 |
|
Male |
|
8/22/2009 |
|
United States |
|
Pruritus |
|
|
|
Female |
|
8/22/2009 |
|
United States |
|
Pruritus |
|
4/1/2009 |
|
Male |
|
8/22/2009 |
|
United States |
|
Flushing |
|
4/1/2009 |
|
Female |
200 lb |
8/22/2009 |
|
United States |
|
Flushing |
|
11/1/2008 |
|
Male |
|
8/23/2009 |
|
United States |
|
Nausea |
|
|
|
Female |
222 lb |
8/23/2009 |
|
United States |
|
Somnolence |
|
|
|
Female |
178 lb |
8/23/2009 |
Other Health Professional |
United States |
|
Urinary Tract Infection |
Hospitalization |
8/17/2009 |
62 |
Female |
226 lb |
8/27/2009 |
|
United States |
|
Swollen Tongue |
Hospitalization |
8/1/2009 |
|
Female |
|
8/26/2009 |
Consumer |
United States |
|
Syncope |
Other Serious |
8/22/2009 |
|
Female |
145 lb |
9/11/2009 |
Other Health Professional |
United States |
|
Syncope |
Other Serious |
8/22/2009 |
|
Female |
145 lb |
9/30/2009 |
|
United States |
|
Weight Increased |
|
12/1/2008 |
75 |
Female |
156 lb |
10/2/2009 |
|
United States |
|
Tinnitus |
Other Serious |
1/1/2008 |
|
Female |
170 lb |
10/23/2009 |
Consumer |
United States |
|
Cardiac Arrest |
Death |
7/15/2009 |
|
Male |
240 lb |
10/28/2009 |
|
United States |
|
Platelet Count Decreased |
Death |
7/6/2009 |
|
Male |
240 lb |
11/10/2009 |
|
United States |
|
Blood Calcium Increased |
|
|
|
Female |
|
11/10/2009 |
Consumer |
United States |
|
Flushing |
|
10/1/2009 |
61 |
Male |
|
11/25/2009 |
|
United States |
|
Weight Decreased |
Hospitalization |
1/1/2009 |
|
Female |
182 lb |
12/3/2009 |
Consumer |
United States |
|
Ulcer |
Other Serious |
1/1/2004 |
|
Female |
|
12/1/2009 |
Consumer |
United States |
|
Weight Increased |
Disability |
10/21/2009 |
|
Female |
|
12/10/2009 |
Other Health Professional |
United States |
|
Weight Decreased |
Hospitalization |
10/1/2009 |
|
Female |
165 lb |
12/11/2009 |
Consumer |
United States |
|
Skin Discolouration |
Death |
1/1/2009 |
|
Female |
|
12/15/2009 |
Consumer |
United States |
|
Weight Decreased |
Other Serious |
11/1/2008 |
|
Female |
205 lb |
12/21/2009 |
Consumer |
United States |
|
Urine Odour Abnormal |
|
4/10/2009 |
71 |
Female |
|
1/4/2010 |
Consumer |
United States |
|
Urine Output Decreased |
|
5/1/2009 |
75 |
Female |
|
1/4/2010 |
Consumer |
United States |
|
Urticaria |
|
2/1/2008 |
66 |
Male |
|
1/4/2010 |
Consumer |
United States |
|
Herpes Zoster |
|
9/27/2009 |
|
Female |
135 lb |
1/29/2010 |
Consumer |
United States |
|
Liver Injury |
|
6/19/2008 |
72 |
Female |
|
6/6/2009 |
Physician |
United States |
|
Myalgia |
Other Serious |
|
85 |
Male |
|
4/5/2010 |
Consumer |
United States |
|
Parkinson's Disease |
Other Serious |
|
|
Male |
|
4/8/2010 |
Consumer |
United States |
|
Pneumonia |
Hospitalization |
3/21/2010 |
62 |
Male |
239 lb |
4/27/2010 |
Consumer |
United States |
|
Parkinson's Disease |
Other Serious |
|
|
Male |
|
5/6/2010 |
Consumer |
United States |
|
Dizziness |
|
4/1/2010 |
73 |
Female |
165 lb |
5/20/2010 |
Consumer |
United States |
|
Thrombosis In Device |
Other Serious |
3/25/2010 |
88 |
Male |
|
5/26/2010 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Tooth Infection |
Other Serious |
4/1/2010 |
82 |
Female |
|
6/1/2010 |
Other Health Professional |
United States |
|
Sneezing |
Other Serious |
|
76 |
Female |
|
6/3/2010 |
Consumer |
United States |
|
Tongue Exfoliation |
Other Serious |
|
67 |
Male |
188 lb |
6/4/2010 |
Consumer |
United States |
|
Tongue Exfoliation |
Other Serious |
|
67 |
Male |
188 lb |
6/25/2010 |
Consumer |
United States |
|
Thrombosis In Device |
Other Serious |
3/25/2010 |
88 |
Male |
|
6/28/2010 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vision Blurred |
|
10/22/2007 |
79 |
Male |
170 lb |
6/29/2010 |
Other Health Professional |
United States |
|
Pulmonary Fibrosis |
|
2/23/2009 |
84 |
Female |
128 lb |
6/30/2010 |
Physician |
United States |
|
Renal Failure |
Other Serious |
|
|
Female |
115 lb |
7/8/2010 |
Physician |
United States |
|
Therapeutic Response Decreased |
Other Serious |
1/1/2008 |
65 |
Male |
239 lb |
7/13/2010 |
Physician |
United States |
|
Weight Increased |
|
3/10/2008 |
63 |
Female |
|
7/21/2010 |
Other Health Professional |
United States |
|
Tongue Exfoliation |
Other Serious |
1/1/2010 |
67 |
Male |
190 lb |
7/30/2010 |
Other Health Professional |
United States |
|
Myalgia |
|
1/1/2007 |
63 |
Female |
185 lb |
7/30/2010 |
Consumer |
United States |
|
Pyrexia |
Hospitalization |
8/17/2010 |
69 |
Male |
184 lb |
8/19/2010 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vomiting |
|
5/1/2010 |
72 |
Female |
110 lb |
8/27/2010 |
Physician |
United States |
|
Muscular Weakness |
|
7/30/2009 |
74 |
Male |
232 lb |
8/27/2010 |
|
United States |
|
Flushing |
|
|
|
Female |
210 lb |
8/28/2010 |
|
United States |
|
Hypoaesthesia |
|
10/16/2009 |
56 |
Female |
137 lb |
8/28/2010 |
|
United States |
|
Pain In Extremity |
|
|
|
Male |
|
8/28/2010 |
|
United States |
|
Flushing |
|
1/1/2009 |
78 |
Female |
152 lb |
8/28/2010 |
|
United States |
|
Pruritus |
|
12/1/2009 |
70 |
Male |
144 lb |
8/28/2010 |
Consumer |
United States |
|
Pain In Extremity |
|
2/19/2010 |
76 |
Male |
177 lb |
8/28/2010 |
|
United States |
|
Pyrexia |
Hospitalization |
8/17/2010 |
69 |
Male |
184 lb |
8/31/2010 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Wheelchair User |
Other Serious |
1/1/2004 |
57 |
Male |
174 lb |
9/3/2010 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Pyrexia |
Hospitalization |
8/17/2010 |
69 |
Male |
184 lb |
9/10/2010 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Pyrexia |
Hospitalization |
8/17/2010 |
69 |
Male |
184 lb |
8/31/2010 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Tooth Abscess |
|
11/1/2009 |
72 |
Female |
180 lb |
9/27/2010 |
|
United States |
|
Wheelchair User |
Other Serious |
1/1/2004 |
57 |
Male |
174 lb |
9/30/2010 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Pyrexia |
Hospitalization |
8/17/2010 |
69 |
Male |
184 lb |
10/7/2010 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Osteoporosis |
|
|
74 |
Male |
220 lb |
10/13/2010 |
Consumer |
United States |
|
Wheelchair User |
Other Serious |
1/1/2004 |
57 |
Male |
174 lb |
10/14/2010 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vomiting |
|
5/1/2010 |
72 |
Female |
110 lb |
10/22/2010 |
Physician |
United States |
|
Muscle Spasms |
|
1/1/2008 |
|
Male |
210 lb |
10/26/2010 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
White Blood Cell Count Decreased |
Other Serious |
5/7/2005 |
58 |
Male |
174 lb |
10/27/2010 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Oral Pain |
|
|
67 |
Male |
|
10/13/2010 |
Consumer |
United States |
|
Product Quality Issue |
|
|
62 |
Female |
|
10/13/2010 |
Consumer |
United States |
|
Pharyngeal Disorder |
|
|
79 |
Female |
|
10/13/2010 |
Consumer |
United States |
|
Micturition Frequency Decreased |
|
9/29/2010 |
65 |
Female |
|
11/16/2010 |
Consumer |
United States |
|
Throat Irritation |
|
9/27/2010 |
72 |
Male |
200 lb |
12/8/2010 |
Consumer |
United States |
|
Urinary Tract Infection |
|
3/11/2010 |
|
|
|
12/19/2010 |
Consumer |
United States |
|
White Blood Cell Count Decreased |
Other Serious |
5/7/2005 |
58 |
Male |
174 lb |
12/24/2010 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Eye Pain |
Other Serious |
11/14/2010 |
74 |
Female |
|
1/7/2011 |
|
United States |
|
Flatulence |
|
|
52 |
Female |
|
1/7/2011 |
Consumer |
United States |
|
Diarrhoea |
|
|
70 |
Female |
|
1/7/2011 |
Consumer |
United States |
|
Skin Ulcer |
|
|
66 |
Female |
|
1/7/2011 |
Consumer |
United States |
|
Vision Blurred |
Other Serious |
7/27/2010 |
69 |
Female |
146 lb |
1/7/2011 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Sinus Congestion |
|
|
64 |
Male |
|
1/12/2011 |
Consumer |
United States |
|
Breast Mass |
Other Serious |
4/1/2010 |
71 |
Female |
175 lb |
1/13/2011 |
Consumer |
United States |
|
Dysstasia |
Other Serious |
1/1/2009 |
85 |
Female |
140 lb |
1/17/2011 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Hyperhidrosis |
|
8/14/2010 |
63 |
Female |
|
1/29/2011 |
Consumer |
United States |
|
Intervertebral Disc Degeneration |
Hospitalization |
5/7/2005 |
58 |
Male |
174 lb |
2/18/2011 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Haemorrhoids |
|
1/1/2011 |
57 |
Male |
|
2/24/2011 |
Consumer |
United States |
|
Fatigue |
Other Serious |
4/1/2010 |
69 |
Female |
|
2/25/2011 |
Physician |
United States |
|
Bronchitis |
Hospitalization |
|
|
Female |
|
3/7/2011 |
Consumer |
United States |
|
Swollen Tongue |
Life Threatening |
|
69 |
Female |
185 lb |
3/9/2011 |
Physician |
United States |
|
Pharyngeal Oedema |
Hospitalization |
8/1/2009 |
79 |
Female |
|
3/16/2011 |
Consumer |
United States |
|
Flushing |
Other Serious |
1/1/2009 |
86 |
Male |
|
3/17/2011 |
Consumer |
United States |
|
Bronchitis |
Hospitalization |
|
|
Female |
135 lb |
3/30/2011 |
Consumer |
United States |
|
Herpes Simplex Serology Positive |
Other Serious |
5/7/2005 |
58 |
Male |
174 lb |
4/5/2011 |
Lawyer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Bronchitis |
Hospitalization |
|
|
Female |
135 lb |
4/5/2011 |
Consumer |
United States |
|
Urinary Tract Infection |
Hospitalization |
1/1/2011 |
73 |
Male |
174 lb |
4/7/2011 |
Pharmacist |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Headache |
|
2/1/2011 |
69 |
Female |
|
4/18/2011 |
Consumer |
United States |
|
Oedema Peripheral |
|
|
|
Female |
|
4/20/2011 |
Consumer |
United States |
|
Dizziness |
|
3/9/2011 |
81 |
Female |
|
4/20/2011 |
Consumer |
United States |
|
Bronchitis |
Hospitalization |
|
|
Female |
135 lb |
4/25/2011 |
Physician |
United States |
|
Death |
Death |
|
79 |
Female |
|
4/26/2011 |
Other Health Professional |
United States |
|
Diabetic Ketoacidosis |
Hospitalization |
1/1/2011 |
73 |
Male |
174 lb |
4/28/2011 |
Pharmacist |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Hypersensitivity |
Hospitalization |
1/1/2011 |
73 |
Male |
174 lb |
4/29/2011 |
Pharmacist |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Coronary Artery Occlusion |
Other Serious |
1/1/2009 |
86 |
Male |
|
4/28/2011 |
Consumer |
United States |
|
Eye Haemorrhage |
|
2/1/2011 |
69 |
Female |
|
5/4/2011 |
Consumer |
United States |
|
Pruritus |
Other Serious |
9/14/2007 |
66 |
Female |
|
5/5/2011 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Gastrointestinal Disorder |
Hospitalization |
3/13/2011 |
72 |
Male |
|
5/10/2011 |
Consumer |
United States |
|
Oesophageal Pain |
|
1/1/2011 |
75 |
Female |
|
5/16/2011 |
Consumer |
United States |
|
Hypersensitivity |
|
|
|
Female |
|
5/31/2011 |
Other Health Professional |
United States |
|
Hypertension |
Other Serious |
|
44 |
Male |
|
5/31/2011 |
Physician |
United States |
|
Memory Impairment |
Hospitalization |
4/27/2011 |
81 |
Female |
|
5/25/2011 |
Physician |
United States |
|
Pruritus |
Other Serious |
|
|
Female |
130 lb |
6/7/2011 |
Consumer |
United States |
|
Constipation |
Other Serious |
3/1/2010 |
79 |
Female |
271 lb |
6/21/2011 |
Consumer |
United States |
|
Arthralgia |
Other Serious |
3/1/2010 |
79 |
Female |
271 lb |
6/21/2011 |
|
United States |
|
Memory Impairment |
Other Serious |
2/1/2011 |
84 |
Male |
|
6/21/2011 |
Consumer |
United States |
|
Fatigue |
Hospitalization |
3/15/2011 |
81 |
Male |
|
6/24/2011 |
Physician |
United States |
|
Toxoplasma Serology Positive |
Hospitalization |
5/7/2005 |
58 |
Male |
174 lb |
6/29/2011 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Breast Swelling |
|
5/13/2011 |
71 |
Male |
|
7/18/2011 |
Consumer |
United States |
|
Bone Disorder |
Other Serious |
2/7/2011 |
|
Male |
|
7/21/2011 |
Physician |
United States |
|
Hypoaesthesia |
Other Serious |
4/27/2011 |
81 |
Female |
|
7/22/2011 |
Consumer |
United States |
|
Chylothorax |
Hospitalization |
4/24/2011 |
62 |
Female |
149 lb |
8/2/2011 |
Physician |
United States |
|
Weight Increased |
Other Serious |
3/1/2010 |
79 |
Female |
271 lb |
8/2/2011 |
|
United States |
|
Flushing |
|
|
|
Male |
260 lb |
8/5/2011 |
Consumer |
United States |
|
Pharyngeal Oedema |
|
9/6/2010 |
60 |
Female |
148 lb |
8/5/2011 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Dizziness |
|
5/23/2011 |
80 |
Male |
174 lb |
8/6/2011 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|