Celecoxib combined with Leflunomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rheumatoid Arthritis Other Serious 5/1/2005 Male 181 lb 1/18/2006 United Kingdom
Primary
Concomitant
Sepsis Hospitalization 12/12/2005 Male 220 lb 2/9/2006 Canada
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 5/9/2005 58 Female 150 lb 12/27/2005 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/3/2004 Male 161 lb 3/29/2006 France
Primary
Concomitant
Pustular Psoriasis Other Serious 1/25/2006 Female 3/31/2006 Physician Belgium
Primary
Concomitant
Streptococcal Sepsis Hospitalization 12/12/2005 Male 220 lb 4/6/2006 Physician Canada
Primary
Concomitant
Pustular Psoriasis Other Serious 1/25/2006 Female 5/4/2006 Physician Belgium
Primary
Concomitant
Nodule Other Serious 4/3/2005 Female 170 lb 5/5/2006 Consumer Canada
Primary
Concomitant
Weight Decreased Hospitalization 12/12/2005 Male 225 lb 5/19/2006 Physician Canada
Primary
Concomitant
Osteonecrosis Hospitalization 9/15/2003 67 Female 5/31/2006 Other Health Professional Australia
Primary
Concomitant
Osteonecrosis Hospitalization 9/15/2003 67 Female 6/5/2006 Physician Australia
Primary
Concomitant
Hip Arthroplasty Hospitalization 5/5/2006 Female 140 lb 6/7/2006 Consumer Canada
Primary
Concomitant
Thrombosis Hospitalization 1/1/2003 62 Female 7/13/2006 Consumer Australia
Primary
Concomitant
Coronary Artery Thrombosis Death 4/4/2006 Male 185 lb 7/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lung Neoplasm Hospitalization 3/29/2005 Female 146 lb 7/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/25/2005 Male 181 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Lesion 8/15/2005 Male 148 lb 8/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 5/2/2006 Male 188 lb 8/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Stiffness Hospitalization 10/4/2004 Male 223 lb 12/28/2006 Consumer United Kingdom
Primary
Concomitant
Syncope Hospitalization 4/29/2005 Female 104 lb 1/17/2007 Consumer United Kingdom
Primary
Concomitant
Coronary Artery Thrombosis Death 4/4/2006 Male 185 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Paraesthesia Hospitalization 4/29/2006 70 Female 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psoriasis Hospitalization Female 1/25/2007 Physician Belgium
Primary
Concomitant
Tachycardia Other Serious 9/26/2006 Male 212 lb 2/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Breast Mass Other Serious Female 148 lb 2/9/2007 Consumer Canada
Primary
Concomitant
Psoriasis Hospitalization Female 2/9/2007 Physician Belgium
Primary
Concomitant
Wound Drainage Other Serious 10/28/2005 Female 2/16/2007 Physician Belgium
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/18/2005 Female 2/21/2007 Physician Belgium
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 9/15/2003 67 Female 3/5/2007 Physician Australia
Primary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 1/24/2007 Female 110 lb 4/12/2007 Italy
Primary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 4/1/2006 Female 110 lb 4/25/2007 Italy
Primary
Concomitant
Viral Infection Other Serious 2/6/2006 Female 129 lb 5/22/2007 Consumer Canada
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pustular Psoriasis Hospitalization 12/25/2006 Female 6/7/2007 Other Health Professional Australia
Primary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 4/1/2006 Female 110 lb 6/25/2007 Italy
Primary
Concomitant
Pain In Extremity Hospitalization 1/1/2005 59 Female 170 lb 6/13/2007 Physician United States
Primary
Concomitant
Pustular Psoriasis Hospitalization 12/25/2006 Female 7/16/2007 Consumer Australia
Primary
Concomitant
Myocardial Infarction Other Serious 12/2/2005 74 Female 118 lb 7/9/2007 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/7/2007 Female 137 lb 8/30/2007 Germany
Primary
Concomitant
Visual Disturbance Other Serious Female 130 lb 9/28/2007 Canada
Primary
Concomitant
Jaundice Other Serious 9/20/2007 72 Male 10/24/2007
Primary
Concomitant
Psoriasis Hospitalization 2/20/2007 Male 148 lb 11/13/2007 United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 9/11/2007 72 Male 11/21/2007
Primary
Concomitant
Visual Disturbance Other Serious 8/10/2007 Female 130 lb 12/3/2007 Canada
Primary
Concomitant
Multiple Fractures Hospitalization 3/5/2004 Female 146 lb 12/7/2007 United Kingdom
Primary
Concomitant
Viral Infection Hospitalization 12/20/2006 Male 146 lb 12/7/2007 United Kingdom
Primary
Concomitant
Salmonellosis 1/1/2006 Female 166 lb 12/14/2007 United States
Primary
Concomitant
Injection Site Irritation 9/1/2007 Female 120 lb 12/14/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 1/1/2005 Female 135 lb 12/14/2007 Consumer United States
Primary
Concomitant
Pruritus 11/1/2006 Female 135 lb 12/14/2007 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 8/1/2007 Female 152 lb 12/28/2007 Germany
Primary
Concomitant
Pneumonia Legionella Hospitalization 7/16/2007 31 Male 2/8/2008 Germany
Primary
Concomitant
Interacting
Liver Function Test Abnormal Other Serious 9/11/2007 72 Male 2/13/2008
Primary
Concomitant
Pneumonia Legionella Hospitalization 7/16/2007 31 Male 2/19/2008 Germany
Primary
Concomitant
Interacting
Renal Ischaemia Death 10/3/2007 Female 104 lb 2/25/2008 United Kingdom
Primary
Concomitant
Wheezing Other Serious 12/3/2007 38 Female 128 lb 2/25/2008 Pharmacist United Kingdom
Primary
Concomitant
Rash Male 3/14/2008 Consumer United States
Primary
Concomitant
Injection Site Swelling 11/1/2007 Female 135 lb 3/14/2008 Consumer United States
Primary
Concomitant
Vomiting 1/14/2008 Female 183 lb 3/15/2008 United States
Primary
Concomitant
Injection Site Urticaria 1/31/2008 Female 124 lb 3/15/2008 United States
Primary
Concomitant
Vomiting 2/15/2008 Female 205 lb 3/15/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/29/2007 Female 187 lb 4/25/2008 United Kingdom
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 1/1/2004 Female 110 lb 5/16/2008 United States
Primary
Concomitant
Skin Burning Sensation 1/1/2007 Male 190 lb 6/11/2008 United States
Primary
Concomitant
Injection Site Nodule 9/1/2007 Female 6/12/2008 United States
Primary
Concomitant
Sneezing 5/14/2008 Female 228 lb 6/13/2008 Consumer United States
Primary
Concomitant
Infarction Hospitalization 2/21/2008 Male 6/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/15/2007 Female 187 lb 7/11/2008 United Kingdom
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/21/2008 Male 7/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thoracic Vertebral Fracture Other Serious 5/1/2008 Male 132 lb 7/21/2008 Korea, Republic Of
Primary
Concomitant
Surgery Hospitalization 7/1/2007 Male 242 lb 7/24/2008 Consumer United States
Primary
Concomitant
Thoracic Vertebral Fracture Other Serious 5/1/2008 62 Male 132 lb 8/1/2008 Physician Korea, Republic Of
Primary
Concomitant
Thoracic Vertebral Fracture Other Serious 5/1/2008 62 Male 132 lb 8/13/2008 Physician Korea, Republic Of
Primary
Concomitant
Staphylococcal Infection Other Serious 7/7/2007 Female 137 lb 8/13/2008 Germany
Primary
Secondary
Concomitant
Skin Burning Sensation 1/1/2007 Male 190 lb 9/12/2008 United States
Primary
Concomitant
Breast Tenderness 5/1/2008 Female 9/12/2008 United States
Primary
Concomitant
Injection Site Pain 12/1/2006 Male 185 lb 9/12/2008 Consumer United States
Primary
Concomitant
Sinusitis 5/1/2008 Female 9/12/2008 United States
Primary
Concomitant
Arthralgia Hospitalization Female 9/15/2008 Germany
Primary
Concomitant
Arthralgia Hospitalization Female 9/24/2008 Germany
Primary
Concomitant
Iridocyclitis Other Serious 5/1/2006 Female 99 lb 10/7/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Other Serious 4/1/2003 Female 10/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Dislocation Of Joint Prosthesis Other Serious Female 11/18/2008 Brazil
Primary
Concomitant
Staphylococcal Skin Infection 7/1/2008 Female 220 lb 12/12/2008 Consumer United States
Primary
Concomitant
Wheezing 7/1/2008 Female 217 lb 12/12/2008 Physician United States
Primary
Concomitant
Underdose Male 180 lb 12/12/2008 Consumer United States
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 10/27/2008 Female 110 lb 12/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/14/2008 12/17/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 10/27/2008 Female 110 lb 12/29/2008 Physician United States
Primary
Secondary
Concomitant
Visual Field Defect Hospitalization 2/21/2008 Male 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urosepsis Hospitalization Female 187 lb 7/1/2009 United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 6/12/2008 73 7/28/2009 Physician Peru
Primary
Secondary
Concomitant
Incorrect Dose Administered 10/30/2006 Male 190 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 12/23/2006 Female 120 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 3/29/2007 Female 145 lb 9/11/2009 Consumer Puerto Rico
Primary
Concomitant
Incorrect Dose Administered 1/1/2005 Female 135 lb 9/12/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 5/14/2008 Female 228 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 12/1/2006 Male 185 lb 9/12/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 7/1/2008 Female 220 lb 9/12/2009 Consumer United States
Primary
Concomitant
Shock Life Threatening 9/5/2009 Male 154 lb 9/24/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/28/2009 Female 10/12/2009 United Kingdom
Primary
Concomitant
Vaginal Infection Other Serious 5/8/2009 46 Female 233 lb 10/20/2009 Other Health Professional United States
Primary
Concomitant
Septic Shock Life Threatening 9/5/2009 Male 154 lb 11/2/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Myocardial Infarction Life Threatening 6/12/2008 73 Female 163 lb 11/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 Female 101 lb 1/28/2010 Brazil
Primary
Concomitant
Myocardial Infarction Life Threatening 6/12/2008 73 Female 163 lb 3/3/2010 Physician Peru
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/28/2009 Female 3/26/2010 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 6/12/2008 73 Female 163 lb 4/6/2010 Physician Peru
Primary
Secondary
Concomitant
Pneumonia Legionella Hospitalization 7/16/2007 31 Male 6/24/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Femur Fracture Hospitalization 10/1/2009 68 Female 7/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/1/2009 68 Female 9/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/22/2010 Physician South Africa
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/24/2010 Physician South Africa
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/24/2010 Physician South Africa
Primary
Concomitant
Infective Exacerbation Of Chronic Obstructive Airways Disease Hospitalization 12/15/2009 59 Female 95 lb 11/30/2010 Consumer United Kingdom
Primary
Concomitant
Drug Ineffective 12/14/2010 Physician United States
Primary
Concomitant
Upper Limb Fracture Other Serious 3/8/2009 12/16/2010 Consumer United States
Primary
Concomitant
Rash Pruritic 9/1/2009 12/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain 12/22/2010 Consumer United States
Primary
Concomitant
Injection Site Urticaria 5/24/2010 12/22/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 12/23/2010 Physician South Africa
Primary
Concomitant
Injection Site Erythema 7/11/2010 12/23/2010 Consumer United States
Primary
Concomitant
Angina Pectoris Other Serious 11/1/2007 68 Female 117 lb 1/17/2011 Physician Brazil
Primary
Concomitant
Atrial Fibrillation Hospitalization 11/4/2010 63 Male 158 lb 1/18/2011 Physician South Africa
Primary
Concomitant
Incorrect Storage Of Drug 11/1/2009 5/12/2011 Physician United States
Primary
Concomitant
Encephalitis Hospitalization 64 Female 6/3/2011 Physician United Kingdom
Primary
Concomitant
Rectal Haemorrhage Hospitalization 5/1/2011 62 Male 250 lb 6/15/2011 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 5/1/2011 62 Male 250 lb 6/22/2011 Consumer United States
Primary
Concomitant
Bursitis Other Serious 1/31/2011 72 Female 93 lb 6/23/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Hepatitis B Hospitalization 1/11/2011 60 Female 165 lb 9/30/2011 Physician Japan
Primary
Concomitant
Multi-organ Failure Hospitalization 9/16/2010 61 Female 265 lb 10/3/2011 Physician Romania
Primary
Secondary
Concomitant
Soft Tissue Mass Other Serious 1/31/2011 72 Female 93 lb 10/27/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Injection Site Warmth 2/1/2011 56 Female 11/1/2011 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 11/4/2010 63 Male 158 lb 11/11/2011 Physician South Africa
Primary
Concomitant
Restless Legs Syndrome Hospitalization 6/2/2010 66 Female 11/23/2011 Physician Czech Republic
Primary
Concomitant
Pain In Extremity Hospitalization 6/2/2010 66 Female 11/28/2011 Physician Czech Republic
Primary
Concomitant
Musculoskeletal Pain Hospitalization 8/8/2010 66 Female 11/29/2011 Physician Czech Republic
Primary
Concomitant
Intervertebral Disc Displacement Hospitalization Female 11/29/2011 Physician Czech Republic
Primary
Concomitant
Hepatitis B Dna Increased Hospitalization 1/11/2011 60 Female 165 lb 1/3/2012 Other Health Professional Japan
Primary
Concomitant
Cough Other Serious Female 123 lb 1/6/2012 Consumer Colombia
Primary
Concomitant
Decreased Appetite Other Serious Female 123 lb 1/20/2012 Other Health Professional Malaysia
Primary
Concomitant
Multi-organ Failure Death 9/16/2010 61 Female 265 lb 1/24/2012 Physician Romania
Primary
Secondary
Concomitant
Leukopenia Other Serious 1/1/2005 66 Male 1/27/2012 Physician United States
Primary
Secondary
Concomitant
Sarcoidosis Other Serious 50 Male 2/20/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Sarcoidosis Other Serious 50 Male 3/29/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Lymphadenopathy Mediastinal Other Serious 50 Male 4/9/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Sarcoidosis Other Serious 50 Male 4/10/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Sarcoidosis Other Serious 50 Male 4/10/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Rash Generalised Other Serious 5/1/2011 66 Female 139 lb 4/11/2012 Consumer Brazil
Primary
Secondary
Concomitant
Angiotensin Converting Enzyme Increased Other Serious 50 Male 5/1/2012 Other Health Professional Australia
Primary
Secondary

Drug Data