Cefepime combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 3/3/2005 72 183 lb 9/12/2005 Physician United States
Primary
Concomitant
Pulmonary Haemorrhage Death 10/7/2004 50 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Renal Failure Chronic Required Intervention 11/9/2005 79 Female 1/16/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization Female 1/19/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 10/10/2005 Female 10/18/2005 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/14/2005 Female 2/14/2006 Physician United States
Primary
Concomitant
Injection Site Reaction Death 11/16/2005 66 Male 146 lb 11/30/2005 Pharmacist United States
Primary
Concomitant
Tachycardia Required Intervention 3/9/2006 61 Male 67 lb 3/15/2006 Other Health Professional United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Death 1/9/2006 85 Male 167 lb 3/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hallucination, Visual Hospitalization 4/1/2006 48 Male 165 lb 4/11/2006 Pharmacist United States
Primary
Concomitant
Insomnia Other Serious 5/2/2006 Male 441 lb 5/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Wound Secretion Death 5/7/2004 10 Female 6/5/2006 United States
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 7/4/2005 50 Male 6/19/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 5/25/2006 60 Male 198 lb 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2006 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Neutropenia 4/11/2006 71 Female 143 lb 7/6/2006 Physician United States
Primary
Secondary
Concomitant
Scrotal Operation Required Intervention 11/17/2005 46 Male 8/15/2006 Pharmacist United States
Primary
Concomitant
Blood Pressure Decreased Death 6/14/2006 Female 249 lb 8/21/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/15/2006 40 Male 8/30/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/26/2006 86 Male 119 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Paraesthesia Oral Life Threatening 8/31/2006 27 Male 139 lb 11/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 5/21/2005 74 Male 11/15/2006 United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Life Threatening 10/17/2006 43 Female 155 lb 10/22/2006 United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/1/2007 80 Male 1/30/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/11/2006 68 Female 2/9/2007 Brazil
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/11/2006 68 Female 2/20/2007 Physician Brazil
Primary
Secondary
Concomitant
Mental Impairment Other Serious 3/1/2007 Female 132 lb 3/23/2007 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 11/6/2006 54 Female 265 lb 11/8/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 4/24/2007 80 Male 198 lb 4/25/2007 Physician United States
Primary
Concomitant
Rash Other Serious 4/24/2007 80 Male 198 lb 4/25/2007 Physician United States
Primary
Concomitant
Mental Impairment Other Serious 3/1/2007 Female 132 lb 5/18/2007 Pharmacist United States
Primary
Concomitant
Oral Candidiasis Other Serious 3/18/2007 65 Male 6/29/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 6/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 7/16/2007 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Required Intervention 7/8/2007 59 Male 209 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 7/1/2007 66 Female 144 lb 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 7/27/2007 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/1/2007 66 Female 144 lb 8/13/2007 Physician United States
Primary
Secondary
Concomitant
Thrombosis Required Intervention 6/17/2007 35 Male 88 lb 6/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 6/8/2007 Male 107 lb 6/11/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/11/2007 9 Female 56 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 11/15/2007 Male 29 lb 11/19/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/11/2007 9 Female 56 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 11/13/2007 60 Male 238 lb 12/28/2007 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 11/13/2007 60 Male 238 lb 1/4/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 2/15/2007 63 Male 3/17/2008 Physician Korea, Republic Of
Primary
Concomitant
Rash Other Serious 3/19/2008 60 Male 197 lb 5/5/2008 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 3/19/2008 60 Male 197 lb 5/7/2008 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 5/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 3/5/2008 Male 122 lb 5/23/2008 Other Health Professional Belgium
Primary
Secondary
Concomitant
Tricuspid Valve Disease Other Serious 3/20/2008 60 Male 197 lb 5/15/2008 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 5/22/2008 Consumer United States
Primary
Secondary
Concomitant
Skin Exfoliation Life Threatening 3/9/2008 Female 143 lb 3/18/2008 Pharmacist United States
Primary
Concomitant
Fatigue Hospitalization 3/5/2008 Male 122 lb 7/3/2008 Other Health Professional Belgium
Primary
Secondary
Concomitant
Sepsis Other Serious 0 Male 7/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 0 Male 4 lb 7/16/2008 Other Health Professional United States
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 9/17/2000 Male 7/17/2008 Physician United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 7/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 12/5/2007 62 Male 7/18/2008 Physician United States
Primary
Concomitant
Sepsis Death Male 10 lb 7/29/2008
Primary
Secondary
Weight Increased Other Serious 5/29/2008 Female 114 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 8/15/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 8/15/2008 Other Health Professional Brazil
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 3/20/2008 62 Male 154 lb 8/13/2008 Pharmacist United States
Primary
Concomitant
Sepsis Death 22 Male 8/28/2008 Pharmacist United States
Primary
Concomitant
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 9/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Death 9/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 9/9/2008 9 Male 97 lb 10/6/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/29/2008 Female 114 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 10/16/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 10/16/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 166 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Strongyloidiasis Hospitalization 31 Male 11/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Potassium Increased Life Threatening 6/24/2008 Male 167 lb 7/2/2008 United States
Primary
Concomitant
Urinary Bladder Haemorrhage Other Serious 9/9/2008 9 Male 97 lb 11/14/2008 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 9/9/2008 10 Male 97 lb 11/20/2008 Physician United States
Primary
Secondary
Concomitant
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 9/9/2008 10 Male 97 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Convulsion Required Intervention 12/17/2008 9 Male 109 lb 12/22/2008 Pharmacist United States
Primary
Concomitant
Extrapyramidal Disorder Other Serious 8/12/2008 52 Male 156 lb 1/7/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Septic Shock Death 1/14/2009 Male 2/18/2009 Pharmacist New Zealand
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 9/9/2008 10 Male 97 lb 2/13/2009 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 67 Male 4/9/2009
Primary
Secondary
White Blood Cell Count Increased Required Intervention 3/9/2009 46 Female 170 lb 4/3/2009 Pharmacist United States
Primary
Concomitant
Leukaemia Recurrent Hospitalization 12/26/2006 20 5/12/2009 Physician France
Primary
Concomitant
Parotitis Hospitalization 4/22/2009 Female 150 lb 5/14/2009 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/23/2006 40 Male 150 lb 5/18/2009 Consumer United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 4/27/2009 Female 144 lb 6/1/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Syncope Hospitalization 4/22/2009 Male 6/23/2009 United States
Primary
Concomitant
Hallucination Hospitalization 4/27/2009 Female 144 lb 6/24/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Hallucination Life Threatening 3/7/2009 30 Male 174 lb 4/3/2009 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 6/13/2009 11 Male 84 lb 6/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11/1/2007 63 Male 179 lb 8/28/2009 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 6/1/2009 Female 9/18/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2007 78 Female 9/21/2009 Lawyer United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 6/1/2009 Female 9/24/2009 Physician United States
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Other Serious 70 Male 10/1/2009 United States
Primary
Secondary
Acute Generalised Exanthematous Pustulosis Hospitalization 70 Male 10/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 70 Male 10/13/2009 Physician United States
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 70 Male 10/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 6/1/2009 Female 10/16/2009 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 10/12/2009 Male 30 lb 10/16/2009 Other Health Professional United States
Primary
Concomitant
Streptococcal Infection Hospitalization 70 Male 10/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 70 Male 10/22/2009 United States
Primary
Secondary
Streptococcal Infection Hospitalization 70 Male 10/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 70 Male 11/19/2009 Physician United States
Primary
Secondary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 12/22/2009 Pharmacist Spain
Primary
Concomitant
Night Sweats Hospitalization 10/23/2009 Male 142 lb 12/29/2009 United States
Primary
Secondary
Concomitant
Rash 10/31/2009 72 Male 267 lb 1/6/2010 Pharmacist United States
Primary
Concomitant
Blood Bilirubin Increased 10/21/2009 77 Male 161 lb 1/13/2010 Other Health Professional United States
Primary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 1/21/2010 Pharmacist Spain
Primary
Concomitant
Ventricular Tachycardia Other Serious 9/1/2007 75 Male 3/1/2010 Lawyer United States
Primary
Concomitant
Hyperglycaemia 2/16/2010 Male 71 lb 2/25/2010 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 3/10/2010 Female 130 lb 3/14/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2010 Female 130 lb 3/18/2010 United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 3/23/2010 United States
Primary
Concomitant
Radiotherapy Other Serious 1/1/2005 40 Male 4/6/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 28 Female 4/15/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 28 Female 4/20/2010 Other Health Professional United States
Primary
Concomitant
Waldenstrom's Macroglobulinaemia Other Serious 1/1/2007 80 Male 157 lb 4/20/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/13/2009 11 Male 84 lb 4/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 10/13/2009 18 Male 4/22/2010 Physician Brazil
Primary
Concomitant
Thrombosis Other Serious 28 Female 4/27/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 28 Female 4/30/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 67 Female 129 lb 5/14/2010 Lawyer United States
Primary
Concomitant
Stomatitis Other Serious 16 Female 5/21/2010
Primary
Secondary
Ventricular Tachycardia Other Serious 9/1/2007 75 Male 132 lb 5/24/2010 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization Male 204 lb Other Health Professional United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 6/9/2010 58 Female 101 lb 6/14/2010 Pharmacist United States
Primary
Concomitant
Vaginal Lesion Hospitalization 4/14/2010 3 Female 43 lb 6/17/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
Vomiting Hospitalization 4/4/2010 3 Female 43 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 12/1/2007 74 Female 6/23/2010 Lawyer United States
Primary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 73 Female 6/25/2010 United States
Primary
Concomitant
Respiratory Failure Other Serious 1/28/2008 66 Female 7/8/2010 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 73 Female 7/2/2010 United States
Primary
Concomitant
Vomiting Death 1/1/2008 50 Female 7/21/2010 Lawyer United States
Primary
Concomitant

Drug Data