Cefazolin combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Hepatic Failure Hospitalization 10/26/2005 44 Female 1/24/2006 Physician Germany
Primary
Concomitant
Troponin Increased Other Serious 10/17/2005 53 Male 165 lb 1/31/2006 Physician Italy
Primary
Concomitant
Malignant Hypertension Life Threatening 9/20/2004 46 Female 2/2/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 10/26/2005 44 Female 2/6/2006 Physician Germany
Primary
Concomitant
Urticaria Hospitalization 6/23/2005 52 Male 220 lb 2/8/2006 Other Health Professional France
Primary
Secondary
Hepatic Function Abnormal Required Intervention 12/13/2005 57 Male 148 lb 3/2/2006 Physician Japan
Primary
Secondary
Concomitant
Anaphylactoid Reaction Other Serious 8/15/2005 69 Male 176 lb 9/23/2005 Other Health Professional United States
Primary
Concomitant
Sudden Death Death 1/1/2005 38 Female 3/2/2006 Physician Belgium
Primary
Secondary
Concomitant
Mental Status Changes Life Threatening 6/14/2004 49 Female 3/14/2006 United States
Primary
Concomitant
Drug Ineffective 3/2/2006 33 Male 3/14/2006 Portugal
Primary
Concomitant
Malignant Hypertension Life Threatening 9/20/2004 46 Female 3/24/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Troponin Increased Other Serious 10/17/2005 53 Male 165 lb 4/6/2006 Physician Italy
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/13/2005 49 Female 265 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Thirst Other Serious 59 Female 4/28/2006 Consumer Japan
Primary
Secondary
Concomitant
Thirst Other Serious 59 Female 5/1/2006 Consumer Japan
Primary
Secondary
Concomitant
Urinary Casts Other Serious 23 Male 4/21/2006 United States
Primary
Concomitant
Rash Erythematous Life Threatening 1/31/2006 61 Male 5/16/2006 Consumer Australia
Primary
Secondary
Wound Haemorrhage Other Serious 35 Female 116 lb 5/23/2006 Physician China
Primary
Secondary
Concomitant
Urticaria Generalised Other Serious 23 Male 5/24/2006 Physician United States
Primary
Concomitant
Rash Erythematous Life Threatening 1/31/2006 61 Male 7/18/2006 Consumer Australia
Primary
Secondary
Respiratory Distress Other Serious 8/28/2005 16 Male 8/26/2006 Physician Canada
Primary
Concomitant
Wound Secretion Other Serious 35 Female 116 lb 9/1/2006 Other Health Professional China
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 35 Female 116 lb 9/28/2006 United States
Primary
Concomitant
Interacting
Pulmonary Hypertension Hospitalization 8/22/2005 73 Female 170 lb 8/29/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 9/7/2006 68 Male 229 lb 10/9/2006 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 21 Male 174 lb 10/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Hypotension Life Threatening 56 Female 12/21/2006 Consumer Australia
Primary
Secondary
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Malaise Hospitalization 10/26/2005 44 Female 110 lb 1/15/2007 Germany
Primary
Concomitant
Neurological Symptom Other Serious 9/27/2005 Male 251 lb 3/12/2007 Physician United States
Primary
Concomitant
Drug Interaction Life Threatening 12/11/2006 39 Female 139 lb 4/19/2007 Physician Germany
Primary
Concomitant
Interacting
Prothrombin Level Abnormal Hospitalization 5/16/2007 70 Male 6/15/2007 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/17/2007 53 Female 6/22/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Prothrombin Level Decreased Hospitalization 5/16/2007 70 Male 6/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
Erythema Other Serious 10/2/2007 51 Male 183 lb 10/16/2007 Other Health Professional Japan
Primary
Concomitant
Prothrombin Level Decreased Hospitalization 5/16/2007 Male 10/26/2007 Other Health Professional France
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 9/17/2007 Female 11/16/2007 Other Health Professional France
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 10/29/2007 56 Female 12/6/2007 Germany
Primary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Septic Shock Other Serious 10/1/2007 65 Male 1/22/2008 Consumer United States
Primary
Secondary
Concomitant
Hypertension Other Serious 69 Female 1/17/2008 Physician Australia
Primary
Secondary
Concomitant
Post Procedural Discharge Other Serious 9/26/2007 Female 2/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Hypertension Other Serious 69 Female 150 lb 1/25/2008 Physician United States
Primary
Secondary
Concomitant
Central Venous Pressure Increased Required Intervention 1/24/2008 56 Male 293 lb 1/29/2008 Physician Germany
Primary
Concomitant
Palatal Oedema Hospitalization 50 Male 154 lb 2/6/2008
Primary
Secondary
Concomitant
Shock Life Threatening 7/16/2007 25 Female 2/15/2008 Other Health Professional France
Primary
Secondary
Central Venous Pressure Increased Required Intervention 1/23/2008 56 Male 293 lb 2/11/2008 Physician Germany
Primary
Concomitant
Shock Life Threatening 7/16/2007 25 Female 2/22/2008 Other Health Professional France
Primary
Secondary
Post Procedural Complication Hospitalization 69 Female 3/5/2008 Australia
Primary
Secondary
Concomitant
Hypertension Other Serious 69 Female 150 lb 3/28/2008 Australia
Primary
Concomitant
Interacting
Liver Injury Other Serious 5/6/2007 46 Male 6/29/2007 Physician United States
Primary
Concomitant
Haemorrhage Other Serious 6/28/2004 64 Male 4/29/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Deafness Unilateral Disability 38 Female 4/24/2008 Physician United States
Primary
Secondary
Concomitant
Deafness Neurosensory Other Serious 38 Female 5/1/2008 United States
Primary
Secondary
Concomitant
Rhabdomyolysis 4/17/2008 37 Male 5/20/2008 Japan
Primary
Concomitant
Deafness Neurosensory Other Serious 38 Female 5/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/17/2008 37 Male 5/28/2008 Japan
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 11/20/2007 Female 7/2/2008 Other Health Professional France
Primary
Secondary
Concomitant
Deafness Neurosensory Other Serious 1/1/2008 38 Female 7/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/29/2006 70 Female 7/16/2008 New Zealand
Primary
Concomitant
Syncope Hospitalization 3/30/2008 80 Male 7/23/2008 New Zealand
Primary
Concomitant
Skin Ulcer Hospitalization 8/4/2008 Female 139 lb 8/7/2008 United States
Primary
Concomitant
Anaphylactic Shock Hospitalization 11/20/2007 Female 8/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/30/2008 80 Male 8/14/2008 New Zealand
Primary
Concomitant
Skin Ulcer Hospitalization 9/8/2008 Female 136 lb 9/10/2008 United States
Primary
Concomitant
Skin Ulcer Hospitalization 9/8/2008 Female 136 lb 9/12/2008 United States
Primary
Concomitant
Grand Mal Convulsion Life Threatening 6/22/2008 69 Female 9/11/2008 New Zealand
Primary
Secondary
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Acute Hepatic Failure Hospitalization 1/18/2007 Male 10/16/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Death 9/11/2008 11 Female 90 lb 10/23/2008 Other Health Professional United States
Primary
Concomitant
Tachycardia Life Threatening 5/26/2008 56 Male 11/10/2008 Consumer France
Primary
Secondary
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Hemiparesis Other Serious 9/2/2008 81 Female 101 lb 11/25/2008 Pharmacist United States
Primary
Concomitant
Post Procedural Complication Other Serious 5/15/2008 87 Female 139 lb 11/25/2008 Pharmacist United States
Primary
Concomitant
Myoclonic Epilepsy Other Serious 10/10/2008 69 Female 137 lb 11/26/2008 Pharmacist United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 11/12/2008 63 Male 12/15/2008 Physician Switzerland
Primary
Concomitant
Interacting
Urosepsis Other Serious 1/1/2008 63 Male 12/17/2008 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Rash Macular Life Threatening 1/6/2009 Female 111 lb 1/8/2009 Pharmacist United States
Primary
Concomitant
Meniscus Lesion Hospitalization Female 126 lb 1/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 11/18/2008 Female 1/20/2009 Physician France
Primary
Secondary
Meniscus Lesion Hospitalization 11/23/2008 Female 127 lb 2/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 71 Female 2/20/2009 Lawyer United States
Primary
Concomitant
Anaphylactic Shock Life Threatening 11/18/2008 Female 3/2/2009 Physician France
Primary
Secondary
Breath Sounds Absent Other Serious 32 Male 3/23/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Breath Sounds Abnormal Other Serious 33 Male 3/23/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Paraesthesia Hospitalization 4/10/2009 Male 170 lb 4/13/2009 United States
Primary
Concomitant
Vomiting Required Intervention 51 Male 192 lb 4/22/2009 Other Health Professional United States
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 12/25/2008 51 Female 143 lb 1/16/2009 Pharmacist United States
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 2/24/2009 Female 4/29/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Other Serious 2/20/2009 Male 4/30/2009 Physician Germany
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 2/12/2009 Male 4/30/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Other Serious 2/23/2009 Male 5/8/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 5/19/2009 Male 203 lb 5/20/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 51 Male 192 lb 6/2/2009 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 12/1/2005 51 Male 192 lb 6/10/2009 Pharmacist United States
Primary
Concomitant
Wound Infection Hospitalization 5/19/2009 Male 203 lb 6/11/2009 Consumer United States
Primary
Concomitant
Left Ventricular Hypertrophy Other Serious 51 Male 192 lb 6/15/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2008 Female 220 lb 7/2/2009 Consumer United States
Primary
Concomitant
Anaphylactic Shock Life Threatening 11/18/2008 Female 8/4/2009 Physician France
Primary
Secondary
Urinary Tract Infection Hospitalization 9/21/2009 Male 166 lb 9/23/2009 Consumer United States
Primary
Concomitant
Wheezing Other Serious 9/29/2009 38 Male 10/7/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Neuromuscular Block Prolonged Hospitalization 10/20/2009
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 12/11/2008 60 Male 11/10/2009 Other Health Professional France
Primary
Secondary
Wheezing Other Serious 9/29/2009 38 Male 11/19/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 71 Female 146 lb 12/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Complication Required Intervention 11/13/2009 47 Male 174 lb 11/16/2009 Pharmacist United States
Primary
Concomitant
Snoring Hospitalization 50 Male 1/19/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 2/4/2010 Consumer Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 11/3/2003 Male 3/25/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2010 41 Female 3/31/2010 Physician Hungary
Primary
Secondary
Concomitant
Liver Injury Hospitalization 11/25/2004 51 Female 3/31/2010 Other Health Professional Australia
Primary
Concomitant
Hypotension Hospitalization 3/1/2010 51 Male 4/2/2010 Australia
Primary
Secondary
Vomiting Other Serious 11/3/2003 47 Male 4/11/2010 Other Health Professional United States
Primary
Concomitant
Liver Injury Hospitalization 11/25/2004 51 Female 4/14/2010 Other Health Professional Australia
Primary
Concomitant
Vomiting Other Serious 1/1/2005 71 Female 146 lb 4/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/3/2003 47 Male 4/30/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 49 Female 115 lb 5/11/2010 Physician Korea, Republic Of
Primary
Concomitant
Wound Necrosis Other Serious 6/1/2008 33 Male 6/17/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 7/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 5/10/2010 72 Female 194 lb 7/5/2010 Other Health Professional Australia
Primary
Secondary
Vomiting Other Serious 11/3/2003 47 Male 180 lb 7/13/2010 United States
Primary
Concomitant
Tachycardia Life Threatening 2/2/2010 99 Female 7/14/2010 Other Health Professional Australia
Primary
Secondary
Tachycardia Life Threatening 2/2/2010 Female 7/19/2010 Other Health Professional Australia
Primary
Secondary
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 7/28/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 4/28/2008 74 Male 190 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Wound Necrosis Other Serious 6/1/2008 33 Male 8/11/2010 Lawyer United States
Primary
Concomitant
Hepatitis 1/4/2008 51 Female 5/13/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 8/23/2010 Other Health Professional United States
Primary
Concomitant
Convulsion Hospitalization 8/13/2010 43 Female 161 lb 9/13/2010 Physician United States
Primary
Concomitant
Pharyngeal Oedema Hospitalization 50 Male 9/1/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus 11/1/2003 43 Female 151 lb 9/20/2010 United States
Primary
Concomitant
Dermatitis Exfoliative Other Serious 1 Male 9/29/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 10/11/2010 United States
Primary
Concomitant
Vomiting Other Serious 11/3/2003 47 Male 180 lb 10/14/2010 United States
Primary
Concomitant
Vomiting Other Serious 11/3/2003 47 Male 180 lb 10/27/2010 United States
Primary
Concomitant
Vomiting Other Serious 11/3/2003 47 Male 180 lb 11/8/2010 United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 2/12/2010 33 Female 11/18/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 11/4/2010 66 Female 106 lb 11/29/2010 Consumer France
Primary
Concomitant
Wound Haemorrhage Other Serious 12/1/2007 57 Female 12/2/2010 Other Health Professional United States
Primary
Concomitant
Hypertension Other Serious 11/24/2010 50 Male 161 lb 12/3/2010 Physician Chile
Primary
Concomitant
Anaphylactic Shock Life Threatening 4/8/2008 62 Female 110 lb 12/16/2010 Other Health Professional France
Primary
Secondary
Papule Hospitalization 10/26/2010 31 Female 12/3/2010 Other Health Professional
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 12/23/2010 United States
Primary
Concomitant
Dyskinesia Other Serious 11/24/2010 50 Male 161 lb 1/6/2011 Physician Chile
Primary
Concomitant
Hypertension Other Serious 11/24/2010 50 Male 161 lb 1/7/2011 Physician Chile
Primary
Concomitant
Dyspnoea Other Serious 1/1/2007 65 Male 1/17/2011 United States
Primary
Concomitant

Drug Data