Cefazolin combined with Heparin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 11/1/2005 37 Male 163 lb 2/6/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 12/16/2005 52 Male 2/7/2006 Pharmacist United States
Primary
Concomitant
Respiratory Acidosis Hospitalization 9/23/2005 65 Male 213 lb 3/15/2006 Pharmacist United States
Primary
Secondary
Ventricular Tachycardia Other Serious 31 Male 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/13/2005 49 Female 265 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 50 4/23/2006 Physician Australia
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Required Intervention 7/16/2005 51 Female 12/13/2005 United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 5/18/2006 United States
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased 50 Female 5/15/2006 Physician Australia
Primary
Secondary
Concomitant
Wound Secretion Other Serious 8/1/2004 74 Female 114 lb 6/29/2006 United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 7/18/2006 United States
Primary
Secondary
Concomitant
Transfusion Reaction Hospitalization 4/29/2006 82 Male 149 lb 7/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Venous Pressure Increased Hospitalization 4/29/2006 82 Male 149 lb 7/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 1/13/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles Death 8/13/2006 46 Male 331 lb 10/2/2006 Other Health Professional Poland
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 115 lb 10/30/2006 Physician United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 10/29/2006 56 Female 154 lb 10/29/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 9/14/2006 61 Male 11/7/2006 Other Health Professional Lithuania
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 Female 11/9/2006 Consumer Germany
Primary
Secondary
Concomitant
Sinus Tachycardia Required Intervention 3 Female 28 lb 12/14/2006 United States
Primary
Concomitant
Respiratory Failure Other Serious 9/14/2006 61 Female 12/26/2006 Other Health Professional Lithuania
Primary
Concomitant
Hyperamylasaemia Other Serious 5/28/2006 39 Male 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Systemic Mycosis Death 11/22/2006 3 Female 33 lb 1/2/2007 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 10/19/2006 60 Male 2/9/2007 Pharmacist United States
Primary
Concomitant
Neurological Symptom Other Serious 9/27/2005 Male 251 lb 3/12/2007 Physician United States
Primary
Concomitant
Rash Generalised Other Serious 10/20/2006 60 Male 93 lb 3/6/2007 Physician Nepal
Primary
Secondary
Viral Infection Other Serious 11/17/2006 66 Male 3/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 11/6/2006 54 Female 265 lb 11/8/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Death 8/13/2006 46 Male 331 lb 4/24/2007 Other Health Professional Poland
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 3/27/2007 61 Male 165 lb 4/3/2007 Pharmacist United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 5/23/2007 Male 209 lb 9/5/2007 Physician Spain
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/6/2007 60 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2006 60 Male 10/29/2007 United States
Primary
Secondary
Concomitant
Laryngeal Oedema Hospitalization 10/24/2007 66 Male 174 lb 11/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Injury Other Serious 5/21/2007 65 Female 101 lb 11/30/2007 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/18/2007 46 Female 1/4/2008 Other Health Professional Canada
Primary
Concomitant
Platelet Count Decreased Other Serious 1/2/2008 87 Female 123 lb 1/8/2008 Pharmacist United States
Primary
Concomitant
Central Venous Pressure Increased Required Intervention 1/24/2008 56 Male 293 lb 1/29/2008 Physician Germany
Primary
Concomitant
Dermatitis Exfoliative Generalised Hospitalization 1/8/2008 36 Female 157 lb 1/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 11/21/2006 2/14/2008 Physician Canada
Primary
Concomitant
Central Venous Pressure Increased Required Intervention 1/23/2008 56 Male 293 lb 2/11/2008 Physician Germany
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 5/10/2007 82 Female 104 lb 3/3/2008 Pharmacist United States
Primary
Secondary
Concomitant
Endocarditis Other Serious Female 155 lb 4/18/2008 Other Health Professional United States
Primary
Concomitant
Haemorrhage Other Serious 6/28/2004 64 Male 4/29/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Endocarditis Other Serious Female 155 lb 4/29/2008 Other Health Professional United States
Primary
Concomitant
Haematuria Other Serious 5/7/2008 69 Female 5/13/2008 Pharmacist United States
Primary
Concomitant
Prealbumin Decreased Other Serious 10/18/2006 50 Female 220 lb 5/28/2008 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 10/20/2006 50 Female 6/11/2008 Pharmacist United States
Primary
Concomitant
Peritoneal Haemorrhage Life Threatening 3/1/2008 Female 198 lb 3/14/2008 Pharmacist United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 5/23/2007 Male 209 lb 6/30/2008 Physician Spain
Primary
Concomitant
Drug Ineffective Other Serious 3/26/2008 1 Male 13 lb 4/22/2008 Pharmacist United States
Primary
Concomitant
Skin Ulcer Other Serious 1/1/2006 69 Female 7/28/2008 Lawyer United States
Primary
Concomitant
Death Death 9/30/2005 Female 8/18/2008 Consumer Canada
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 8/4/2008 Female 139 lb 8/7/2008 United States
Primary
Concomitant
Knee Arthroplasty Hospitalization 1/1/2008 Female 146 lb 8/20/2008 Germany
Primary
Concomitant
Urinary Incontinence Other Serious 6/13/2007 11 Male 68 lb 8/27/2008 Lawyer Germany
Primary
Concomitant
Urinary Incontinence Other Serious 6/13/2007 11 Male 68 lb 8/28/2008 Lawyer Germany
Primary
Concomitant
Skin Ulcer Hospitalization 9/8/2008 Female 136 lb 9/10/2008 United States
Primary
Concomitant
Skin Ulcer Hospitalization 9/8/2008 Female 136 lb 9/12/2008 United States
Primary
Concomitant
Rash Hospitalization 6/6/2007 45 Female 9/24/2008 Consumer Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/26/2008 83 Male 139 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Peripheral Ischaemia Hospitalization 5/23/2007 Male 209 lb 10/9/2008 Physician Spain
Primary
Concomitant
Renal Impairment Other Serious 1/10/2008 Male 108 lb 10/23/2008 Physician Japan
Primary
Concomitant
Petechiae Other Serious 5/1/2007 45 Female 10/29/2008 Physician Canada
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/10/2008 Male 108 lb 11/7/2008 Physician Japan
Primary
Concomitant
Haemorrhage Required Intervention 5/22/2008 Female 114 lb 6/24/2008 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2007 45 Female 11/21/2008 Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 8/26/2008 83 Male 139 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Hemiparesis Other Serious 9/2/2008 81 Female 101 lb 11/25/2008 Pharmacist United States
Primary
Concomitant
Partial Seizures Other Serious 10/22/2008 61 Female 220 lb 11/26/2008 Pharmacist United States
Primary
Concomitant
Post Procedural Complication Other Serious 11/18/2008 77 Female 185 lb 11/26/2008 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2007 45 Female 12/4/2008 Canada
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 10/29/2008 78 Female 110 lb 11/26/2008 Pharmacist United States
Primary
Concomitant
Myoclonic Epilepsy Other Serious 10/10/2008 69 Female 137 lb 11/26/2008 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 7/1/2008 Male 137 lb 12/19/2008 Physician Japan
Primary
Concomitant
Paraesthesia Hospitalization 4/10/2009 Male 170 lb 4/13/2009 United States
Primary
Concomitant
Somnolence Required Intervention 1/14/2009 21 Female 119 lb 1/14/2009 United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 3/17/2009 86 Female 134 lb 3/18/2009 Pharmacist United States
Primary
Concomitant
Wound Dehiscence Other Serious 2/16/2009 Female 223 lb 5/5/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombosis In Device Death 2/13/2009 Male 121 lb 5/15/2009 Other Health Professional Japan
Primary
Concomitant
Post Procedural Haematoma Other Serious 2/16/2009 Female 223 lb 5/15/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 6/1/2008 21 Male 216 lb 5/11/2009 Pharmacist United States
Primary
Concomitant
Skin Ulcer Hospitalization 5/19/2009 Male 203 lb 5/20/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombosis In Device Death 2/13/2009 Male 121 lb 6/13/2009 Other Health Professional Japan
Primary
Concomitant
Wound Infection Hospitalization 5/19/2009 Male 203 lb 6/11/2009 Consumer United States
Primary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Thrombosis In Device Death 2/13/2009 Male 121 lb 6/25/2009 Other Health Professional Japan
Primary
Concomitant
Unevaluable Event Life Threatening Female 150 lb 6/24/2009 Pharmacist United States
Primary
Concomitant
Depressed Level Of Consciousness Life Threatening 4/1/2009 Male 183 lb 4/11/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 3/3/2009 Male 7/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vena Cava Thrombosis Other Serious 11 Female 150 lb 8/6/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 11 Female 150 lb 9/1/2009 Physician United States
Primary
Secondary
Concomitant
Vena Cava Thrombosis Hospitalization 11 Female 150 lb 9/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/21/2009 Male 166 lb 9/23/2009 Consumer United States
Primary
Concomitant
Somnolence Life Threatening 8/26/2009 65 Male 8/27/2009 Pharmacist United States
Primary
Concomitant
Vena Cava Thrombosis Other Serious 11 Female 150 lb 9/25/2009
Primary
Secondary
Vena Cava Thrombosis Other Serious 11 Female 150 lb 10/1/2009 Other Health Professional Germany
Primary
Secondary
Sick Sinus Syndrome Life Threatening 10/21/2009 86 Male 185 lb 12/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sick Sinus Syndrome Life Threatening 10/21/2009 86 Male 185 lb 12/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Glucose Increased Required Intervention 10/6/2009 81 Male 201 lb 10/7/2009 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Required Intervention 10/20/2009 25 Female 206 lb 10/21/2009 Physician United States
Primary
Concomitant
Sick Sinus Syndrome Life Threatening 10/21/2009 86 Male 185 lb 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Incorrect Dose Administered Life Threatening 1/28/2010 71 Female 130 lb 2/1/2010 Pharmacist United States
Primary
Concomitant
Respiratory Failure 2/20/2010 40 Female 102 lb 2/22/2010 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 2/8/2010 69 Male 223 lb 2/9/2010 Pharmacist United States
Primary
Concomitant
Incision Site Haemorrhage Other Serious 2/8/2010 68 Female 183 lb 2/9/2010 Pharmacist United States
Primary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 12/16/2009 71 Female 150 lb 5/21/2010 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2010 46 Female 176 lb 5/24/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 5/27/2004 Female 11 lb 6/21/2010 United States
Primary
Concomitant
Coagulation Time Prolonged 78 Male 130 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 73 Female 6/25/2010 United States
Primary
Concomitant
Weight Increased Other Serious 73 Female 7/2/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 3/7/2010 46 Female 176 lb 7/12/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 5/27/2004 Female 11 lb 7/22/2010 United States
Primary
Concomitant
Urinary Incontinence Other Serious 73 Female 7/12/2010 United States
Primary
Concomitant
Renal Failure Other Serious 4/30/2008 15 Female 88 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2004 55 Female 180 lb 8/20/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2004 55 Female 180 lb 9/1/2010 United States
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 1 Male 9/29/2010 United States
Primary
Concomitant
Vomiting Other Serious 11/13/2008 16 Female 97 lb 10/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/13/2008 16 Female 97 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 10/20/2010 United States
Primary
Secondary
Concomitant
Pneumonia Cryptococcal Other Serious 5/28/2006 39 Male 109 lb 10/12/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 1/1/2006 69 Female 11/5/2010 Lawyer United States
Primary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 12/23/2010 United States
Primary
Secondary
Concomitant
Urticaria Other Serious 12/9/2010 50 Male 225 lb 3/9/2011 Pharmacist United States
Primary
Concomitant
Injury Other Serious 11/8/2006 60 Male 168 lb 3/10/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 9/1/2005 71 Male 221 lb 3/9/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 11/8/2006 60 Male 168 lb 3/10/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 7/15/2005 58 Male 205 lb 3/14/2011 Consumer United States
Primary
Concomitant
Injury Hospitalization 7/15/2005 58 Male 205 lb 3/14/2011 Other Health Professional United States
Primary
Concomitant
Injury Death 1/24/2003 68 Male 169 lb 3/14/2011 Consumer United States
Primary
Concomitant
Injury Death 1/24/2003 68 Male 169 lb 3/14/2011 Consumer United States
Primary
Concomitant
Urticaria Other Serious 12/9/2010 50 Male 225 lb 3/15/2011 Pharmacist United States
Primary
Concomitant
Cardiomyopathy Other Serious 9/20/2005 Female 178 lb 3/16/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 9/20/2005 Female 178 lb 3/16/2011 Consumer United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Life Threatening 3/5/2011 70 Male 162 lb 3/16/2011 Physician United States
Primary
Concomitant
Fear Hospitalization 3/11/2006 65 Male 195 lb 3/17/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Other Serious 3/11/2006 65 Male 195 lb 3/17/2011 Lawyer United States
Primary
Concomitant
Anhedonia Hospitalization 10/1/2006 70 Male 127 lb 3/18/2011 Consumer United States
Primary
Concomitant
Pain Hospitalization 2/1/2000 52 Male 235 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Renal Failure Hospitalization 2/1/2000 52 Male 235 lb 3/22/2011 Other Health Professional United States
Primary
Concomitant
Injury Other Serious 7/1/2003 74 Female 175 lb 3/23/2011 Other Health Professional United States
Primary
Concomitant
Fear Other Serious 7/1/2003 74 Female 175 lb 3/23/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 10/21/2003 58 Female 180 lb 3/23/2011 Lawyer United States
Primary
Concomitant
Depression Other Serious 6/15/2005 57 Male 190 lb 3/23/2011 Lawyer United States
Primary
Concomitant

Drug Data