Caspofungin combined with Vancomycin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 11/9/2005 64 Male 171 lb 1/5/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 2/7/2005 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Graft Versus Host Disease Death 1/13/2006 31 Female 218 lb 1/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Infection Other Serious 10/12/2005 63 Female 1/18/2006 Pharmacist United States
Primary
Concomitant
Tracheostomy Life Threatening 7/10/2005 42 Female 1/23/2006 United Kingdom
Primary
Secondary
Concomitant
Skin Hyperpigmentation Life Threatening 1/13/2006 Female 187 lb 1/23/2006 Pharmacist United States
Primary
Concomitant
Respiratory Rate Increased Life Threatening 11/8/2005 70 Female 1/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Multi-organ Failure Death 1/1/2005 72 Male 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Death 4/25/2005 76 Female 113 lb 2/7/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Life Threatening 2/1/2006 63 Female 121 lb 2/14/2006 Physician United States
Primary
Concomitant
Therapy Non-responder Death 2/1/2006 47 Female 123 lb 3/10/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 49 Male 3/20/2006 United States
Primary
Secondary
Concomitant
Ultrasound Abdomen Abnormal Life Threatening 4/9/2006 55 NotSpecified 170 lb 4/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Life Threatening 11/20/2005 70 Female 4/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/2/2006 47 Male 230 lb 3/29/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Death 3/26/2006 73 Male 4/24/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2005 45 Female 165 lb 5/22/2006 Physician United States
Primary
Concomitant
Ill-defined Disorder Life Threatening 5/24/2006 Female 148 lb 5/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stem Cell Transplant Death 6/9/2006 Female 245 lb 6/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenic Infection Hospitalization 5/15/2006 68 Male 148 lb 6/24/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Other Serious 1/1/2005 23 Male 7/19/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/15/2006 40 Male 8/30/2006 Consumer United States
Primary
Concomitant
Urine Sodium Abnormal Death 7/2/2006 76 Male 9/27/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/1/2006 76 Male 10/2/2006 United States
Primary
Concomitant
Tumour Lysis Syndrome Required Intervention 1/1/2006 37 Female 9/28/2006 Physician United States
Primary
Concomitant
Viral Infection Hospitalization 9/29/2006 47 Female 266 lb 10/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Required Intervention 8/30/2006 37 Female 10/13/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Required Intervention 8/30/2006 37 Female 11/7/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 8/30/2006 37 Female 11/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Swollen Tongue Required Intervention 7/13/2006 77 Male 160 lb 7/20/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Life Threatening 1/3/2007 30 Male 168 lb 1/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/24/2007 30 Male 202 lb 1/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Level Decreased Other Serious 31 Female 3/19/2007
Primary
Concomitant
Interacting
Band Neutrophil Count Increased Hospitalization 2/6/2007 Male 99 lb 4/30/2007 Physician United States
Primary
Concomitant
Anaemia Haemolytic Autoimmune Other Serious 5/17/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/12/2007 57 Male 204 lb 7/19/2007 Physician United States
Primary
Concomitant
Hyperkalaemia Hospitalization 3/21/2006 76 Male 150 lb 8/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Pyrexia Other Serious 5/12/2007 Male 8/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Hospitalization 10/17/2005 47 Male 230 lb 1/15/2007 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Required Intervention 6/20/2007 28 Female 108 lb 6/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/1/2007 8 Male 88 lb 9/11/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/1/2007 57 Male 9/13/2007 Consumer France
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 8/13/2007 10 Female 75 lb 9/11/2007 Pharmacist United States
Primary
Concomitant
Varicose Vein Life Threatening 6/15/2007 67 Male 190 lb 10/1/2007 Physician United States
Primary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 10/12/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/1/2007 57 Male 10/31/2007 Consumer France
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 1/1/2007 8 Male 88 lb 10/31/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 8/18/2007 8 Male 88 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Tachycardia Hospitalization 11/22/2007 Female 168 lb 12/6/2007 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 11/6/2007 Female 115 lb 11/15/2007 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Death 10/14/2007 37 Female 146 lb 11/14/2007 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 1/1/2008 68 Male 198 lb 1/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Liver Disorder Death 45 Male 1/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Death 45 Male 2/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 2/23/2005 Female 2/14/2008 Physician Germany
Primary
Secondary
Concomitant
Neonatal Disorder Other Serious Female 6 lb 4/1/2008 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/11/2008 63 Male 243 lb 4/15/2008 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/31/2007 80 Male 5/3/2008 United States
Primary
Concomitant
Right Ventricular Failure Life Threatening 2/1/2006 63 Female 121 lb 5/1/2008 Physician United States
Primary
Concomitant
Liver Disorder Death Male 126 lb 5/19/2008 Consumer United States
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Death Male 5/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Disorder Death Male 126 lb 5/30/2008 Consumer United States
Primary
Secondary
Concomitant
Liver Disorder Death Male 126 lb 6/3/2008 Consumer United States
Primary
Secondary
Concomitant
Virus Urine Test Positive Hospitalization 17 Male 6/5/2008
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Death Male 6/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/12/2008 Female 197 lb 5/10/2008 United States
Primary
Concomitant
Tachycardia Hospitalization 11/22/2007 Female 168 lb 6/23/2008 United States
Primary
Secondary
Concomitant
Hypervigilance 10/19/2007 55 Male 174 lb 10/23/2008 United States
Primary
Concomitant
Renal Failure Hospitalization 9/19/2008 Male 150 lb 11/5/2008 Spain
Primary
Concomitant
Hyperkalaemia Hospitalization 3/21/2006 76 Male 150 lb 11/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Potentiating Drug Interaction Other Serious 14 Male 141 lb 11/10/2008 Germany
Primary
Concomitant
Interacting
Renal Disorder Required Intervention 7/5/2008 42 Male 170 lb 8/1/2008 Pharmacist United States
Primary
Concomitant
Lung Injury Other Serious 38 Female 12/3/2008
Primary
Concomitant
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 9/19/2008 Male 150 lb 1/5/2009 Spain
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 7/1/2006 Male 1/23/2009 United States
Primary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 1/23/2009 Pharmacist United States
Primary
Concomitant
Respiratory Failure Life Threatening 11/17/2008 63 Female 166 lb 1/28/2009 Pharmacist United States
Primary
Concomitant
Respiratory Failure Hospitalization 10/5/2008 Male 152 lb 2/4/2009 Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 64 Male 3/13/2009 Other Health Professional Austria
Primary
Concomitant
Nasal Cyst Other Serious 55 Male 3/18/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 40 Male 165 lb 6/25/2009 Physician Spain
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/2/2005 Male 7/1/2009 Physician United States
Primary
Concomitant
Febrile Neutropenia Other Serious 5/9/2009 41 Male 165 lb 7/1/2009 Physician Spain
Primary
Secondary
Concomitant
Sinusitis Aspergillus Other Serious 3 Female 7/2/2009
Primary
Secondary
Vomiting Other Serious 57 Female 7/9/2009 Physician United States
Primary
Secondary
Vomiting Other Serious 57 Female 7/14/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Pneumonia Viral Other Serious 6/20/2009 Female 7/24/2009 Physician Canada
Primary
Secondary
Concomitant
Septic Shock Other Serious 46 Male 7/29/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 7/16/2009 Male 168 lb 8/24/2009 Faroe Islands
Primary
Secondary
Concomitant
Septic Shock Other Serious 46 Male 8/25/2009 Pharmacist United States
Primary
Concomitant
Pneumonia Viral Other Serious 6/20/2009 Female 9/3/2009 Physician Canada
Primary
Secondary
Concomitant
Cardiac Failure Death 8/18/2009 9/18/2009 Physician Germany
Primary
Concomitant
Hepatic Failure Life Threatening 9/4/2009 Female 165 lb 9/25/2009 Physician Romania
Primary
Concomitant
Pneumonia Viral Other Serious 6/20/2009 Female 9/28/2009 Physician Canada
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 9/4/2009 Female 165 lb 9/29/2009 Physician Romania
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 70 Male 10/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 70 Male 10/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/19/2005 75 10/14/2009 Pharmacist United Kingdom
Primary
Concomitant
Cardiac Failure Death 8/18/2009 10/16/2009 Physician Germany
Primary
Concomitant
Subdural Haematoma Hospitalization 7/1/2009 Male 168 lb 10/19/2009 Faroe Islands
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 70 Male 10/22/2009 Physician France
Primary
Secondary
Atrial Fibrillation Other Serious 70 Male 10/23/2009 Physician United States
Primary
Secondary
Death Death 16 10/28/2009 Physician Korea, Republic Of
Primary
Concomitant
Atrial Fibrillation Other Serious 70 Male 11/5/2009 Physician United States
Primary
Secondary
Pleural Effusion Hospitalization 8/18/2009 Male 11/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 16 Female 82 lb 11/9/2009 Physician Korea, Republic Of
Primary
Concomitant
Drug Resistance Other Serious 13 Male 12/29/2009 Physician Netherlands
Primary
Concomitant
Thrombocytopenia Life Threatening 7/6/2009 64 Female 154 lb 1/14/2010 Ireland
Primary
Concomitant
Acute Myeloid Leukaemia Death 7/11/2007 16 Female 82 lb 1/25/2010 Physician Korea, Republic Of
Primary
Concomitant
Pathogen Resistance Death 11 Female 7/22/2010 Physician Italy
Primary
Secondary
Concomitant
Corynebacterium Infection Other Serious 6 Female 9/1/2010 Physician Turkey
Primary
Secondary
Restlessness Life Threatening 7/10/2010 57 Male 163 lb 9/16/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 31 Male 12/17/2010 Pharmacist United States
Primary
Concomitant
Pancytopenia Death 11 Female 12/21/2010 United States
Primary
Secondary
Concomitant
Pneumonia Klebsiella Other Serious 11/2/2010 62 Female 1/10/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hepatomegaly Other Serious 8/20/2010 57 Male 163 lb 1/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Encephalopathy Life Threatening 11/2/2010 45 Male 243 lb 1/19/2011 Physician Switzerland
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2008 73 Female 132 lb 1/27/2011 Other Health Professional United States
Primary
Concomitant
Acute Graft Versus Host Disease In Intestine Death 17 Female 132 lb 1/28/2011 Other Health Professional France
Primary
Concomitant
Interacting
Pyrexia Life Threatening 7/29/2010 57 Male 163 lb 2/24/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hepatosplenic Candidiasis Other Serious Female 2/17/2011 Physician Philippines
Primary
Concomitant
Foot Amputation Other Serious Male 143 lb 4/8/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 4/20/2006 56 Male 4/21/2011 Lawyer United States
Primary
Concomitant
Liver Disorder Other Serious 53 Female 5/23/2011 Physician France
Primary
Concomitant
Aspartate Aminotransferase Increased Death 10/4/2011 51 Male 2/20/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Candidiasis Death 11/1/2011 45 Female 2/24/2012 Physician France
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Other Serious 2/7/2012 82 Female 176 lb 2/28/2012 Physician Belgium
Primary
Secondary
Concomitant
Cardiac Failure Death 8/18/2009 59 Male 9/24/2013 Physician De
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 7/10/2010 58 Male 163 lb 10/19/2012 Physician Nl
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 7/10/2010 58 Male 163 lb 9/6/2013 Consumer Nl
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death Male 168 lb 8/19/2013 Consumer Ca
Primary
Concomitant
Renal Failure Acute Life Threatening 4/25/2012 33 Male 205 lb 8/29/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 8/25/2012 Female 192 lb 12/5/2012 Physician Us
Primary
Secondary
Concomitant
Skin Lesion Life Threatening 7/23/2012 12 Male 181 lb 11/5/2012 Physician Us
Primary
Secondary
Concomitant
Renal Tubular Acidosis Other Serious 11/26/2011 80 Male 10/3/2012 Physician Cn
Primary
Concomitant
Acquired Haemophilia Hospitalization 5/2012 55 Male 2/6/2013 Us
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 58 Female 4/26/2013 Other Health Professional Nl
Primary
Secondary
Atrial Fibrillation Life Threatening 4/22/2013 64 Female 227 lb 5/22/2013 Consumer De
Primary
Secondary
Concomitant
Septic Shock Death 4/30/2012 63 Male 11/2/2012 Physician Us
Primary
Secondary
Concomitant
Ecchymosis Life Threatening 4/5/2011 51 Male 150 lb 4/5/2011 Pharmacist Us
Primary
Concomitant
Drug-induced Liver Injury Other Serious 2/8/2006 36 Male 10/4/2005 Physician Us
Primary
Secondary
Concomitant
Thrombocytopenia Death 62 Female 6/11/2013 Other Health Professional Es
Primary
Concomitant
Interacting

Drug Data