Carvedilol combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 1/12/2006 Czech Republic
Primary
Secondary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Hyperkalaemia Required Intervention 1/10/2006 84 Male 144 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Hypertension Hospitalization 1/10/2006 58 Male 1/30/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 6/28/2004 82 Female 231 lb 2/2/2006 Physician Poland
Primary
Concomitant
Hyperaldosteronism Hospitalization 12/28/2004 73 Female 121 lb 2/3/2006 Consumer France
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/19/2006 66 Male 2/3/2006 Australia
Primary
Secondary
Concomitant
Malaise Other Serious 12/18/2005 57 Female 2/9/2006 Consumer United Kingdom
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/17/2005 63 Female 2/3/2006 Japan
Primary
Concomitant
Vomiting Other Serious 70 Male 2/7/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 12/20/2005 74 Male 187 lb 2/16/2006 Czech Republic
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hepatitis Toxic Other Serious 10/18/2005 77 Male 3/2/2006 Physician Spain
Primary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 2/28/2006 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 64 Male 2/28/2006 Israel
Primary
Concomitant
Epistaxis Hospitalization 1/30/2006 87 Male 3/1/2006 Pharmacist Ireland
Primary
Concomitant
Vomiting Other Serious 1/19/2006 66 Male 3/3/2006 Australia
Primary
Secondary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 3/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 52 Female 3/16/2006 Physician France
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 84 3/24/2006 Physician Czech Republic
Primary
Concomitant
White Blood Cell Count Increased Death 9/9/2004 73 Male 3/31/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 3/31/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 1/18/2006 67 Male 165 lb 4/13/2006 Physician Germany
Primary
Concomitant
Staphylococcal Sepsis Other Serious 3/15/2006 29 Female 78 lb 4/11/2006 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 1/16/2006 81 Female 4/13/2006 Czech Republic
Primary
Secondary
Concomitant
Neck Pain Death 2/16/2006 82 Male 205 lb 4/4/2006 Consumer United States
Primary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Required Intervention 4/13/2006 76 Male 160 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Methaemoglobinaemia Life Threatening 6/20/2005 17 Female 117 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Hospitalization 11/16/2005 29 Male 4/19/2006 Physician Australia
Primary
Concomitant
Sudden Death Death 2/6/2006 55 Female 168 lb 4/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 4/1/2002 70 Male 4/27/2006 Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/16/2006 81 Female 5/1/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 4/12/2006 56 Male 132 lb 4/28/2006 Japan
Primary
Concomitant
Ocular Hyperaemia Required Intervention 4/17/2006 Male 188 lb 5/10/2006 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 12/1/2004 84 Female 5/15/2006 Physician Chile
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/23/2006 67 Male 163 lb 5/22/2006 Physician Germany
Primary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis 2/19/2006 84 Male 5/24/2006 Switzerland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 12/7/2001 56 Male 6/13/2006 United States
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 7/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Myalgia Disability 6/19/2006 49 Male 186 lb 7/12/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 6/25/2006 66 Male 248 lb 6/25/2006 Pharmacist United States
Primary
Secondary
Pyrexia Hospitalization 3/31/2006 Female 159 lb 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 3/13/2006 69 Male 190 lb 7/26/2006 Physician Argentina
Primary
Concomitant
Vomiting Life Threatening 2/1/2006 75 Male 150 lb 8/4/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/6/2004 Female 8/7/2006 Physician Japan
Primary
Secondary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 8/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 7/1/2005 90 Female 8/9/2006 Physician Japan
Primary
Concomitant
Mitral Valve Sclerosis Other Serious 5/9/2005 54 Male 154 lb 8/10/2006 Physician Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 73 Male 8/11/2006 Brazil
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 11/7/2005 33 Female 8/15/2006 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 8/17/2005 72 Male 8/8/2006 Consumer United States
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 12/12/2005 72 Female 132 lb 8/30/2006 Pharmacist United States
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 6/22/2006 47 Male 203 lb 9/13/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 9/22/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/14/2006 79 Female 172 lb 5/30/2006 Pharmacist United States
Primary
Concomitant
Renal Impairment Required Intervention 9/23/2005 Male 4/28/2006 United States
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 6/22/2006 47 Male 203 lb 9/20/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 10/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 8/11/2006 75 Female 133 lb 10/6/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/1/2006 75 Male 148 lb 10/10/2006 Physician Germany
Primary
Concomitant
Cardiac Failure Congestive Other Serious 52 Female 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 75 Female 133 lb 10/10/2006 Pharmacist United States
Primary
Concomitant
Nodal Rhythm Hospitalization 9/25/2006 80 Female 10/16/2006 Physician Poland
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/15/2005 79 Female 10/27/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 9/30/2005 66 Female 10/23/2006 Switzerland
Primary
Concomitant
Serotonin Syndrome Hospitalization 9/30/2005 66 Female 10/23/2006 Switzerland
Primary
Concomitant
Visual Acuity Reduced Life Threatening 72 Unknown 114 lb 11/21/2006 Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 5/6/2004 Female 12/7/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 7/1/2003 75 Female 11/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Throat Tightness Other Serious 11/24/2006 52 Male 12/13/2006 Physician United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 12/4/2006 Female 176 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Cardiogenic Shock Death 3/11/2006 91 Male 154 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/30/2005 60 Male 134 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 9/1/2005 Male 1/10/2007 Physician Germany
Primary
Concomitant
Retroperitoneal Haematoma Hospitalization 9/14/2006 62 Male 217 lb 9/27/2006 United States
Primary
Concomitant
Hallucination Hospitalization 12/1/2005 71 Male 10/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 Female 1/16/2007 Consumer Brazil
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/1/2006 79 Male 1/18/2007 Physician China
Primary
Concomitant
Nausea Life Threatening 9/23/2006 56 Male 254 lb 1/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 12/20/2006 72 Male 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Subdural Haemorrhage Hospitalization 1/19/2007 66 Male 1/26/2007 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 12/8/2005 73 Male 1/30/2007 United Kingdom
Primary
Concomitant
Nausea Hospitalization 9/25/2006 80 Female 2/12/2007 Poland
Primary
Secondary
Concomitant
Nausea Life Threatening 9/23/2006 56 Male 254 lb 2/13/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/19/2006 Male 102 lb 2/23/2007 Physician Australia
Primary
Secondary
Concomitant
Sepsis Syndrome Other Serious 9/20/2006 70 Female 134 lb 2/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Life Threatening 9/23/2006 56 Male 254 lb 2/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotonia Hospitalization 10/26/2006 3/6/2007 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/1/2006 79 Male 3/6/2007 Physician China
Primary
Concomitant
Injection Site Irritation Other Serious 3/1/2005 Female 120 lb 3/16/2007 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 52 Female 3/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Injection Site Irritation Other Serious 3/1/2005 Female 120 lb 4/18/2007 Consumer United States
Primary
Concomitant
Cardiac Failure Hospitalization 11/23/2006 92 Male 4/20/2007 Consumer Australia
Primary
Secondary
Concomitant
Skin Discolouration Hospitalization 3/17/2007 86 Male 154 lb 4/23/2007 Other Health Professional France
Primary
Concomitant
Interacting
Injection Site Irritation Other Serious 3/1/2005 Female 120 lb 4/26/2007 Physician United States
Primary
Concomitant
Hypotonia Hospitalization 5/15/2006 70 Male 5/1/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 44 Male 5/2/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Skin Discolouration Hospitalization 3/17/2007 86 Male 154 lb 5/4/2007 Other Health Professional France
Primary
Concomitant
Interacting
Palpitations Other Serious 8/1/2006 38 Female 5/10/2007 Physician United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 44 Male 5/11/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Respiration Abnormal Life Threatening 89 Male 5/16/2007 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 5/25/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization Male 220 lb 6/5/2007 Consumer France
Primary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 6/9/2007 Physician Japan
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Life Threatening 5/30/2007 73 Male 6/13/2007 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2006 84 Female 129 lb 6/15/2007 Consumer United States
Primary
Secondary
Visual Acuity Reduced Hospitalization 72 Female 115 lb 6/22/2007
Primary
Secondary
Photopsia Hospitalization 72 Female 6/25/2007 Japan
Primary
Secondary
Concomitant
Photopsia Hospitalization 72 Female 6/28/2007 Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 7/11/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Field Defect Hospitalization 72 Female 115 lb 7/25/2007 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Life Threatening 10/7/2006 72 Female 78 lb 7/20/2007 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 4/19/2007 Male 7/27/2007 Physician Switzerland
Primary
Secondary
Concomitant
Loss Of Consciousness Disability 4/14/2007 59 Male 243 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/11/2004 52 Male 7/31/2007 Canada
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 72 Female 115 lb 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Tachypnoea Other Serious 4/17/2007 6 Female 30 lb 8/7/2007 Physician Netherlands
Primary
Concomitant
Large Intestine Perforation Life Threatening 10/7/2006 72 Female 78 lb 8/13/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 72 Female 115 lb 8/21/2007 Physician Japan
Primary
Concomitant
Respiration Abnormal Life Threatening 89 Male 8/24/2007 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Life Threatening 10/7/2006 72 Female 78 lb 8/23/2007 Physician Japan
Primary
Secondary
Concomitant
Venous Injury Hospitalization 12/20/2005 74 Male 187 lb 9/7/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/16/2006 81 Female 9/7/2007 United States
Primary
Secondary
Concomitant
Urticaria Life Threatening 8/27/2007 2 Male 28 lb 9/7/2007 Physician Spain
Primary
Secondary
Concomitant
Pruritus Generalised Disability 3/20/2007 Male 9/14/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pruritus Generalised Disability 3/20/2007 Male 9/18/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/6/2007 72 Female 9/26/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 62 Male 9/21/2007 Physician Germany
Primary
Secondary
Concomitant
Pruritus Generalised Disability 3/20/2007 Male 9/27/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2006 62 Male 10/1/2007 Physician Germany
Primary
Secondary
Concomitant
Urticaria Life Threatening 8/27/2007 2 Male 28 lb 10/1/2007 Physician Spain
Primary
Concomitant
Weight Increased Other Serious 2/4/2006 Male 10/5/2007 United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 10/9/2007 Physician Australia
Primary
Secondary
Concomitant
Pneumonia Other Serious 67 Female 146 lb 10/15/2007 Physician Poland
Primary
Concomitant
Pneumonia Other Serious 67 Female 146 lb 10/17/2007 Physician Poland
Primary
Concomitant
Cardiac Failure Hospitalization 79 Male 10/17/2007 Physician Switzerland
Primary
Concomitant
Pneumonia Other Serious 67 Female 146 lb 10/31/2007 Physician Poland
Primary
Concomitant
Urticaria Life Threatening 8/27/2007 1 Male 28 lb 10/30/2007 Physician Spain
Primary
Concomitant
Tryptase Decreased Life Threatening 8/27/2007 1 Male 28 lb 11/9/2007 Physician Spain
Primary
Concomitant
Pulmonary Oedema Other Serious 6/10/2007 Male 200 lb 11/21/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2007 Female 118 lb 12/11/2007 Consumer Argentina
Primary
Concomitant
Pneumonia Hospitalization 12/1/2006 64 Male 12/14/2007 Consumer United States
Primary
Concomitant

Drug Data