Carvedilol combined with Sigmart

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sinus Arrest Other Serious 12/23/2003 84 Male 7/17/2006 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 1/29/2005 68 Male 7/18/2006 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 1/31/2005 86 Female 8/25/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/31/2005 86 Female 8/25/2006 Physician Japan
Primary
Secondary
Concomitant
Sinus Arrest Other Serious 12/23/2003 84 Male 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/31/2005 86 Female 9/21/2006 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 1/8/2005 82 Female 10/16/2006 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/18/2004 78 Female 10/26/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/8/2005 82 Female 11/20/2006 Physician Japan
Primary
Secondary
Concomitant
Mean Cell Volume Decreased Hospitalization 9/8/2008 Female 110 lb 9/16/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 Female 12/16/2009
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 12/21/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 Female 12/22/2009
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 Female 12/23/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 Female 12/23/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 Female 89 lb 1/15/2010 Physician Japan
Primary
Secondary
Concomitant
Mean Cell Volume Decreased Hospitalization 9/8/2008 Female 110 lb 2/18/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 9/10/2008 79 Female 3/26/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Chromaturia Other Serious 2/25/2010 74 Female 3/26/2010 Pharmacist Japan
Primary
Concomitant
Erythema Other Serious 3/12/2010 68 Male 3/29/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 5/15/2009 67 Female 89 lb 3/29/2010 Physician Japan
Primary
Secondary
Concomitant
Erythema Other Serious 3/12/2010 68 Male 4/6/2010 Physician Japan
Primary
Concomitant
Tinnitus Other Serious 3/12/2010 77 Male 4/7/2010 Physician Japan
Primary
Concomitant
Eosinophil Count Increased Hospitalization 2/20/2010 82 Male 108 lb 4/30/2010 Physician Japan
Primary
Secondary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 5/15/2009 67 Female 89 lb 5/5/2010 Physician Japan
Primary
Secondary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 5/15/2009 67 Female 89 lb 6/4/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 12/21/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 Female 12/23/2009 Physician Japan
Primary
Secondary
Concomitant
Cholelithiasis Other Serious 7/22/2010 79 Male 108 lb 1/18/2011 Physician Japan
Primary
Secondary
Concomitant
Ankle Fracture Hospitalization 7/22/2010 79 Male 108 lb 1/25/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 7/22/2010 79 Male 108 lb 1/27/2011 Physician Japan
Primary
Secondary
Concomitant
Eyelid Oedema Other Serious 7/22/2010 79 Male 108 lb 2/4/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Atrophy Hospitalization 7/22/2010 79 Male 108 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 3/4/2011 78 Female 5/11/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/31/2011 55 Male 106 lb 5/19/2011 Physician Japan
Primary
Concomitant
Malnutrition Life Threatening 11/8/2010 84 Male 119 lb 5/19/2011 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 4/5/2011 70 Male 5/19/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Atrophy Other Serious 7/22/2010 79 Male 108 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Ocular Icterus Death 7/22/2010 79 Male 108 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Atrophy Hospitalization 7/22/2010 79 Male 108 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Life Threatening 3/1/2011 57 Male 141 lb 5/31/2011 Physician Japan
Primary
Concomitant
Pulmonary Embolism Death 5/29/2010 57 Male 6/3/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 9/21/2010 73 Female 86 lb 6/3/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Other Serious 1/19/2011 80 Male 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Palpitations Hospitalization 2/17/2003 75 Male 117 lb 6/12/2011 Physician Japan
Primary
Concomitant
General Physical Health Deterioration Life Threatening 11/8/2010 84 Male 119 lb 6/16/2011 Physician Japan
Primary
Concomitant
Peritonitis Life Threatening 3/5/2011 55 Female 119 lb 6/16/2011 Physician Japan
Primary
Concomitant
Urosepsis Hospitalization 4/6/2011 74 Male 132 lb 6/22/2011 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 3/5/2011 55 Female 119 lb 6/22/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/22/2011 68 Male 125 lb 6/22/2011 Physician Japan
Primary
Secondary
Interstitial Lung Disease Hospitalization 3/22/2011 68 Male 125 lb 6/27/2011 Physician Japan
Primary
Secondary
Epilepsy Hospitalization 6/1/2011 83 Male 141 lb 6/27/2011 Physician Japan
Primary
Secondary
Pyrexia Life Threatening 3/5/2011 55 Female 119 lb 6/29/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 3/22/2011 68 Male 6/30/2011 Physician Japan
Primary
Secondary
Musculoskeletal Pain Disability 7/22/2010 79 Male 108 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Ocular Icterus Disability 7/22/2010 79 Male 108 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Anaemia Other Serious 6/6/2009 77 Female 93 lb 7/6/2011 Physician Japan
Primary
Concomitant
Pyrexia Death 3/5/2011 55 Female 119 lb 7/8/2011 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 9/21/2010 73 Female 86 lb 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Death 4/14/2011 90 Male 121 lb 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Death 4/14/2011 90 Male 121 lb 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Constipation Hospitalization 7/22/2010 79 Male 108 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Eyelid Oedema Death 7/22/2010 79 Male 108 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Chest Pain Death 7/22/2010 79 Male 108 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/9/2011 48 Male 190 lb 7/8/2011 Physician Japan
Primary
Concomitant
Epilepsy Hospitalization 6/1/2011 83 Male 141 lb 7/11/2011 Physician Japan
Primary
Secondary
Musculoskeletal Pain Disability 7/22/2010 79 Male 108 lb 7/12/2011 Physician Japan
Primary
Secondary
Concomitant
Concomitant Disease Aggravated Other Serious 2/17/2011 77 Male 126 lb 7/12/2011 Physician Japan
Primary
Concomitant
Pyrexia Death 3/5/2011 55 Female 119 lb 7/15/2011 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 4/6/2011 74 Male 132 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 7/5/2011 75 Male 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Nervous System Disorder Life Threatening 3/5/2011 55 Female 119 lb 7/25/2011 Physician Japan
Primary
Concomitant
Delusion Hospitalization 5/27/2011 84 Male 108 lb 7/26/2011 Physician Japan
Primary
Concomitant
Liver Disorder Life Threatening 3/1/2011 57 Male 141 lb 7/27/2011 Physician Japan
Primary
Concomitant
Nervous System Disorder Life Threatening 3/5/2011 55 Female 119 lb 8/1/2011 Physician Japan
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 3/18/2010 8/4/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/22/2011 68 Male 125 lb 8/8/2011 Physician Japan
Primary
Secondary
Altered State Of Consciousness Hospitalization 5/27/2011 84 Male 108 lb 8/9/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Other Serious 3/22/2011 68 Male 8/11/2011 Physician Japan
Primary
Secondary
Cerebellar Haemorrhage Hospitalization 6/18/2011 61 Male 128 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Carcinoma Hospitalization 7/28/2011 81 Male 104 lb 8/12/2011 Physician Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Other Serious 74 Male 8/18/2011 Pharmacist Japan
Primary
Concomitant
Cerebellar Haemorrhage Hospitalization 6/18/2011 61 Male 128 lb 8/24/2011 Physician Japan
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 2/1/2006 62 Male 8/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Infection Other Serious 6/28/2011 78 Female 99 lb 8/30/2011 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 6/1/2010 75 Male 136 lb 9/5/2011 Other Health Professional Japan
Primary
Concomitant
Subarachnoid Haemorrhage Death 4/8/2011 73 Male 9/15/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Other Serious 6/28/2011 78 Female 99 lb 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 2/17/2010 61 Male 9/27/2011 Physician Japan
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 3/9/2011 48 Male 190 lb 9/28/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 6/6/2009 77 Female 93 lb 9/29/2011 Physician Japan
Primary
Concomitant
Cardiac Aneurysm Hospitalization 7/6/2011 71 Male 139 lb 9/30/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 63 Male 10/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 8/4/2011 71 Male 139 lb 10/11/2011 Physician Japan
Primary
Secondary
Concomitant
Pseudomonas Infection Death 2/17/2010 61 Male 10/11/2011 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/22/2011 83 Female 117 lb 10/11/2011 Physician Japan
Primary
Concomitant
Eosinophilic Oesophagitis Hospitalization 7/28/2011 81 Male 104 lb 10/12/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/21/2010 73 Female 86 lb 10/13/2011 Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 7/10/2008 62 Male 160 lb 10/14/2011 Physician Japan
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 4/8/2011 73 Male 152 lb 10/17/2011 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/1/2010 79 Male 110 lb 10/17/2011 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 9/3/2007 82 Female 88 lb 10/20/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 10/19/2011 74 Male 10/31/2011 Physician Japan
Primary
Secondary
Concomitant
Carotid Artery Occlusion Hospitalization 8/1/2011 82 Male 11/1/2011 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 11/25/2010 89 Male 106 lb 11/4/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 10/19/2011 74 Male 11/9/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombosis In Device Death 4/14/2011 90 Male 121 lb 11/16/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 10/28/2011 74 Male 11/17/2011 Japan
Primary
Concomitant
Anaemia Other Serious 6/6/2009 77 Female 93 lb 11/18/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Other Serious 7/10/2008 62 Male 160 lb 11/23/2011 Physician Japan
Primary
Concomitant
Weight Decreased Life Threatening 3/30/2011 66 Male 181 lb 12/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 5/16/2010 78 Male 132 lb 12/5/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 5/25/2011 60 Female 12/6/2011 Physician Japan
Primary
Concomitant
Marasmus Death 8/12/2011 87 Female 68 lb 12/12/2011 Physician Japan
Primary
Concomitant
Torsade De Pointes Life Threatening 12/4/2011 79 Male 12/9/2011 Physician Japan
Primary
Secondary
Concomitant
Eosinophil Count Increased Other Serious 7/7/2011 81 Female 12/16/2011 Physician Japan
Primary
Concomitant
Intracardiac Thrombus Other Serious 11/17/2010 60 Male 110 lb 12/19/2011 Physician Japan
Primary
Concomitant
Respiratory Failure Death 9/29/2011 74 Male 12/21/2011 Japan
Primary
Concomitant
Toxicity To Various Agents Hospitalization 3/22/2011 66 Male 181 lb 12/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 12/18/2011 71 Male 137 lb 12/28/2011 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 12/20/2011 69 Male 12/28/2011 Physician Japan
Primary
Secondary
Death Death 5/26/2011 79 Male 12/29/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Other Serious 7/10/2008 62 Male 160 lb 12/30/2011 Physician Japan
Primary
Concomitant
Eosinophilic Oesophagitis Hospitalization 7/28/2011 81 Male 104 lb 1/5/2012 Physician Japan
Primary
Concomitant
Gynaecomastia Hospitalization 3/1/2011 60 Male 1/12/2012 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 12/13/2011 71 Male 137 lb 1/13/2012 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 3/1/2011 60 Male 1/17/2012 Physician Japan
Primary
Concomitant
Toxicity To Various Agents Hospitalization 3/22/2011 66 Male 181 lb 1/18/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 12/13/2011 71 Male 139 lb 1/18/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/13/2011 71 Male 139 lb 1/26/2012 Physician Japan
Primary
Concomitant
Sepsis Other Serious 10/21/2010 63 Male 2/3/2012 Physician Japan
Primary
Concomitant
Small Intestine Ulcer Hospitalization 12/17/2011 87 Female 2/6/2012 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Death 1/1/2011 68 Male 130 lb 2/13/2012 Other Health Professional Japan
Primary
Concomitant
Asthma Hospitalization 2/2/2012 81 Male 2/14/2012 Physician Japan
Primary
Secondary
Cardio-respiratory Arrest Hospitalization 2/2/2012 81 Male 2/14/2012 Physician Japan
Primary
Secondary
Small Intestine Ulcer Hospitalization 12/17/2011 87 Female 2/16/2012 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 1/17/2012 78 Female 127 lb 2/17/2012 Physician Japan
Primary
Concomitant
Marasmus Death 8/12/2011 87 Female 68 lb 2/17/2012 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 2/8/2012 83 Female 2/20/2012 Physician Japan
Primary
Secondary
Concomitant
Death Death Male 2/20/2012 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Life Threatening 1/22/2009 59 Male 172 lb 2/21/2012 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Death 5/26/2011 79 Male 2/21/2012 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 12/13/2011 71 Male 139 lb 2/22/2012 Physician Japan
Primary
Secondary
Concomitant
Cheilitis Life Threatening 10/11/2011 73 Male 108 lb 2/28/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Hospitalization 1/17/2012 78 Female 127 lb 2/29/2012 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 2/20/2012 40 Male 2/28/2012 Pharmacist Japan
Primary
Secondary
Restlessness Hospitalization 1/17/2012 78 Female 127 lb 3/2/2012 Physician Japan
Primary
Secondary
Concomitant
Nausea Life Threatening 10/11/2011 73 Male 108 lb 3/2/2012 Physician Japan
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 2/8/2012 83 Female 3/5/2012 Physician Japan
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/17/2012 78 Female 127 lb 3/5/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data