Carvedilol combined with Metolazone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Electromechanical Dissociation Life Threatening 9/12/2005 Male 9/23/2005 United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 1/1/2003 67 Female 230 lb 12/27/2005 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/7/2006 76 Male 134 lb 4/14/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 4/1/2002 70 Male 4/27/2006 Canada
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/14/2006 70 Male 139 lb 5/8/2006 Physician Korea, Republic Of
Primary
Concomitant
Weight Increased Hospitalization 6/9/2006 64 Male 199 lb 6/9/2006 United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 9/30/2005 66 Female 10/23/2006 Switzerland
Primary
Concomitant
Serotonin Syndrome Hospitalization 9/30/2005 66 Female 10/23/2006 Switzerland
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 11/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 12/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Urine Output Increased Other Serious 6/13/2006 89 Male 183 lb 12/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 4/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 12/17/2006 56 Female 245 lb 5/10/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 5/11/2007 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/14/2006 Male 139 lb 6/22/2007 Korea, Republic Of
Primary
Concomitant
Rhabdomyolysis Other Serious 12/26/2006 76 Male 218 lb 7/12/2007 Physician United States
Primary
Concomitant
Loss Of Consciousness Disability 4/14/2007 59 Male 243 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Dyspnoea Hospitalization 7/10/2007 51 Female 10/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myoclonus Required Intervention 1/29/2006 65 Male 12/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 1/29/2006 65 Male 12/18/2007 Other Health Professional France
Primary
Concomitant
Interacting
Shock Haemorrhagic Life Threatening 1/15/2008 Female 247 lb 1/21/2008 United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/15/2008 Female 247 lb 1/25/2008 United States
Primary
Concomitant
Myoclonus Hospitalization 1/1/2006 65 Male 1/30/2008 Pharmacist United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/27/2007 81 Female 1/28/2008 Portugal
Primary
Concomitant
Throat Irritation Required Intervention 9/30/2007 77 Male 257 lb 3/11/2008 Physician United States
Primary
Concomitant
Medication Error Other Serious 12/27/2007 81 Female 3/5/2008 Portugal
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/16/2004 57 Female 194 lb 5/2/2007 United States
Primary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Tachycardia Other Serious 68 Male 5/13/2008 Physician United States
Primary
Concomitant
Vomiting Death 3/17/2008 70 Male 5/28/2008 United States
Primary
Concomitant
Vaginal Haemorrhage Life Threatening 1/15/2008 Female 247 lb 6/13/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Life Threatening 1/15/2008 Female 247 lb 7/11/2008 United States
Primary
Concomitant
Vertigo Positional Hospitalization 6/1/2006 Male 7/15/2008 Physician
Primary
Secondary
Rash Macular 7/11/2008 Female 8/29/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 10/16/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 75 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 76 Male 11/13/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 75 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Pruritus 7/31/2008 Male 11/26/2008 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 59 Female 11/26/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 59 Female 216 lb 1/12/2009
Primary
Secondary
Concomitant
Flushing Hospitalization 1/1/2006 Female 123 lb 1/28/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 76 Male 218 lb 1/29/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 76 Male 218 lb 2/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 1/6/2009 Male 220 lb 3/6/2009 United States
Primary
Concomitant
Blood Glucose Increased 10/14/2008 75 Male 234 lb 2/3/2009 Physician United States
Primary
Concomitant
Muscular Weakness Hospitalization 2/9/2006 41 Male 4/6/2009 Korea, Republic Of
Primary
Concomitant
Xanthopsia Hospitalization 73 Female 166 lb 4/7/2009 United States
Primary
Concomitant
Amyloidosis Death Male 5/6/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 4/6/2009 85 Male 326 lb 7/1/2009 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Congestive Life Threatening 5/11/2009 Male 203 lb 7/15/2009 Canada
Primary
Secondary
Concomitant
Surgery Death 73 Female 7/13/2009 United States
Primary
Concomitant
Urticaria 1/29/2009 61 Male 320 lb 7/24/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 60 Male 8/3/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 73 Male 229 lb 8/4/2009 United States
Primary
Concomitant
Unevaluable Event Death Female 8/20/2009 United States
Primary
Concomitant
Weight Decreased Death 73 Female 8/28/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 47 Male 9/2/2009 United States
Primary
Concomitant
Wheezing Death 60 Male 9/4/2009 United States
Primary
Concomitant
Surgery Hospitalization 47 Male 9/3/2009 United States
Primary
Concomitant
Retroperitoneal Haematoma Required Intervention 11/8/2008 72 Female 234 lb 11/21/2008 Pharmacist United States
Primary
Secondary
Concomitant
Wound Infection Death 56 Male 325 lb 9/22/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 68 Male 229 lb 9/24/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 10/9/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 10/13/2009 United States
Primary
Concomitant
Pain Hospitalization 32 Male 10/15/2009 Lawyer United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 10/16/2009 United States
Primary
Concomitant
Pneumonia Hospitalization Female 10/18/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 10/26/2009 United States
Primary
Concomitant
Pain In Extremity Hospitalization 47 Male 10/27/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 10/27/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 84 Female 10/26/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 84 Female 11/9/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Death 73 Female 11/5/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 11/4/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 11/9/2009 United States
Primary
Concomitant
Social Problem Hospitalization Female 11/3/2009 Lawyer United States
Primary
Concomitant
Tenderness Hospitalization 32 Male 11/18/2009 Lawyer United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 11/16/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 11/17/2009 United States
Primary
Concomitant
X-ray Limb Abnormal Other Serious 72 Male 11/16/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 67 Female 11/24/2009 United States
Primary
Concomitant
Surgery Hospitalization 32 Male 12/1/2009 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 72 Female 12/2/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Peritonitis Bacterial Other Serious 11/1/2008 70 Male 11/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Bacterial Hospitalization 3/1/2008 69 Male 11/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 1/1/2009 64 Male 268 lb 12/16/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 12/17/2009 Other Health Professional France
Primary
Secondary
Concomitant
Surgery Hospitalization 32 Male 12/11/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 72 Female 12/10/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/11/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 12/8/2009 United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Death 60 Male 200 lb 1/11/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/11/2010 United States
Primary
Concomitant
Unevaluable Event Hospitalization 32 Male 1/13/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 61 Male 236 lb 1/11/2010 United States
Primary
Concomitant
Swelling Face Required Intervention 9/21/2009 74 Male 218 lb 1/14/2010 Physician United States
Primary
Concomitant
Weight Decreased 64 Female 1/7/2010 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 1/13/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/20/2010 United States
Primary
Concomitant
Weight Decreased 64 Female 1/21/2010 United States
Primary
Concomitant
Ventricular Tachycardia Death 60 Male 200 lb 1/22/2010 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Tenderness Hospitalization 28 Male 2/5/2010 Lawyer United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 2/5/2010 United States
Primary
Concomitant
Vomiting Other Serious 73 Female 2/5/2010 Lawyer United States
Primary
Concomitant
Wound Other Serious 73 Female 2/5/2010 Consumer United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 2/17/2010 United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Cardiac Arrest Death 2/25/2009 Female 3/12/2010 Physician United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 3/23/2010 United States
Primary
Concomitant
Localised Infection Other Serious Male 4/21/2010 United States
Primary
Concomitant
Wound Other Serious Male 4/28/2010 United States
Primary
Concomitant
Urinary Retention Other Serious 60 Male 236 lb 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Death 84 Female 5/3/2010 Lawyer United States
Primary
Concomitant
Skin Cancer Other Serious 4/18/2010 87 Female 170 lb 5/6/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 5/18/2010 Lawyer United States
Primary
Concomitant
Neuroendocrine Carcinoma Of The Skin Other Serious 4/18/2010 87 Female 170 lb 5/24/2010 United States
Primary
Concomitant
Toe Amputation Other Serious 1/1/2005 Male 5/28/2010 Consumer United States
Primary
Concomitant
Refusal Of Treatment By Patient Death 5/21/2010 76 Female 184 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 28 Male 6/11/2010 Lawyer United States
Primary
Concomitant
Infusion Related Reaction Death 5/21/2010 76 Female 184 lb 6/22/2010 Physician United States
Primary
Concomitant
Leukocytosis Other Serious 3/3/2010 67 Female 6/30/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 80 Female 6/30/2010 United States
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 6/28/2010 Male 239 lb 7/13/2010 Physician United States
Primary
Secondary
Concomitant
Toe Amputation Other Serious 1/1/2005 Male 7/13/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 84 Female 7/16/2010 Lawyer United States
Primary
Concomitant
Tricuspid Valve Incompetence Death 5/21/2010 76 Female 184 lb 7/22/2010 Physician United States
Primary
Concomitant
Skin Burning Sensation Other Serious 4/1/2010 87 Female 170 lb 8/4/2010 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 3/11/2010 57 Male 301 lb 8/17/2010 Pharmacist United States
Primary
Secondary
Concomitant
Blood Glucose Increased Male 250 lb 8/29/2010 Consumer United States
Primary
Concomitant
Ischaemic Cardiomyopathy Death 7/28/2010 64 Male 205 lb 8/30/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 77 Male 201 lb 8/27/2010 United States
Primary
Concomitant
Hypotension Other Serious 12/15/2009 65 Male 316 lb 1/25/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 9/10/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 65 Female 9/23/2010 United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 10/14/2010 83 Male 168 lb 11/3/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 62 Male 11/17/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/16/2009 60 Female 155 lb 12/8/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant

Drug Data