Carvedilol combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 1/17/2006 United States
Primary
Concomitant
Septic Shock Other Serious 6/1/2005 55 Female 1/23/2006 Physician Sweden
Primary
Concomitant
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 61 Female 227 lb 2/9/2006 Physician South Africa
Primary
Concomitant
Circulatory Collapse Hospitalization 1/18/2006 67 Male 165 lb 4/13/2006 Physician Germany
Primary
Concomitant
Neck Pain Death 2/16/2006 82 Male 205 lb 4/4/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Death 1/25/2006 72 Female 150 lb 5/1/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/23/2006 67 Male 163 lb 5/22/2006 Physician Germany
Primary
Concomitant
Headache Other Serious 5/9/2006 46 Male 7/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Uterine Disorder Hospitalization 63 Female 7/27/2006 Korea, Republic Of
Primary
Secondary
Concomitant
Hypoglycaemic Coma Death 6/12/2006 49 Male 8/24/2006 United States
Primary
Concomitant
Therapeutic Response Delayed Life Threatening 3/27/2006 63 Male 174 lb 8/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 11/25/2005 67 Male 159 lb 10/25/2006 United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 3/8/2006 57 Female 220 lb 11/15/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/1/2006 Female 195 lb 11/22/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/26/2006 71 Female 150 lb 2/12/2007 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 52 Female 3/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 9/2/2005 61 Female 3/21/2007 Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 8/23/2007 83 Male 10/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/21/2008 52 Male 3/12/2008 Physician Germany
Primary
Concomitant
Paranoia Hospitalization 1/15/2008 58 Female 262 lb 4/7/2008 Physician Switzerland
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Acute Other Serious 5/20/2008 Male 231 lb 7/11/2008 Physician Australia
Primary
Concomitant
Syncope Other Serious 9/1/2007 Female 7/16/2008 Physician United States
Primary
Concomitant
Musculoskeletal Pain 3/13/2008 65 Female 7/24/2008 Consumer United States
Primary
Concomitant
Chromaturia 7/31/2008 Female 8/21/2008 Consumer United States
Primary
Concomitant
Hypoglycaemia Hospitalization 6/2/2008 Female 157 lb 8/22/2008 Physician Greece
Primary
Concomitant
Throat Irritation 7/10/2008 63 Female 8/15/2008 United States
Primary
Concomitant
Vomiting Hospitalization 1/21/2009 Male 1/22/2009 Pharmacist United States
Primary
Concomitant
Intentional Drug Misuse Other Serious 1/1/2009 2/11/2009 Physician Brazil
Primary
Secondary
Concomitant
Blood Glucose Increased Male 2/24/2009 United States
Primary
Concomitant
Blood Glucose Increased 12/1/2008 Male 2/24/2009 United States
Primary
Concomitant
Eye Haemorrhage Other Serious 3/1/2008 74 Male 168 lb 2/25/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 51 Female 3/23/2009 Consumer United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Other Serious 7/1/2008 3/27/2009 Other Health Professional France
Primary
Concomitant
Rash Pruritic Other Serious 3/16/2009 Female 165 lb 3/27/2009 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/1996 42 Male 4/13/2009 United States
Primary
Concomitant
Atrioventricular Block Complete Hospitalization 4/19/2009 73 Male 4/29/2009 Physician Germany
Primary
Concomitant
Atrioventricular Block Complete Life Threatening 4/19/2009 73 Male 6/10/2009 Physician Germany
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 251 lb 6/3/2009 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious 65 Male 154 lb 6/17/2009 Portugal
Primary
Concomitant
Restless Legs Syndrome Other Serious 1/1/2009 69 Male 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Restless Legs Syndrome 7/6/2009 Female 8/3/2009 Consumer
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2007 Female 8/4/2009 Consumer
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 72 Female 7/22/2009 United States
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 6/1/2008 76 Female 8/7/2009 Physician United States
Primary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 8/4/2009 Other Health Professional United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 7/19/2009 53 Male 128 lb 8/13/2009 Consumer Brazil
Primary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 8/10/2009 United States
Primary
Concomitant
Skin Burning Sensation Female 8/21/2009 United States
Primary
Concomitant
Middle Insomnia 1/1/2007 Male 8/21/2009 United States
Primary
Concomitant
Nightmare 8/22/2008 Male 8/21/2009 United States
Primary
Concomitant
Blood Glucose Increased 6/30/2008 Male 8/21/2009 United States
Primary
Concomitant
Pruritus 9/19/2008 Male 8/22/2009 United States
Primary
Concomitant
Neck Pain Male 8/22/2009 United States
Primary
Concomitant
Flushing Female 8/22/2009 United States
Primary
Concomitant
Flushing 1/1/2005 Male 8/22/2009 United States
Primary
Secondary
Concomitant
Flushing 1/5/2009 Male 8/22/2009 United States
Primary
Concomitant
Hypoglycaemia Other Serious 4/16/2009 57 Female 148 lb 9/2/2009 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Hospitalization 57 Male 9/23/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 2/27/2009 66 Male 236 lb 7/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 9/2/2009 57 Male 10/6/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/8/2007 71 Female 10/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Unemployment Hospitalization 72 Male 11/4/2009 United States
Primary
Concomitant
Flushing 7/1/2009 Female 155 lb 11/25/2009 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 70 Male 12/14/2009 United States
Primary
Concomitant
Cardiomyopathy Other Serious 68 Male 12/11/2009 United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/5/2010 61 Male 1/20/2010 Physician United States
Primary
Secondary
Concomitant
Sleep Disorder Life Threatening 10/1/2009 48 Male 353 lb 1/22/2010 Physician United States
Primary
Concomitant
Cardiac Disorder Hospitalization 11/1/2009 Male 165 lb 1/25/2010 Consumer Brazil
Primary
Concomitant
Procedural Complication 10/6/2009 Female 207 lb 1/29/2010 United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 8/3/2009 Male 278 lb 2/12/2010 Physician Denmark
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/1/2009 74 Female 2/11/2010 Consumer United States
Primary
Secondary
Concomitant
Rash Macular Other Serious 3/4/2010 Female 175 lb 3/17/2010 Consumer United States
Primary
Concomitant
Cardiac Disorder Death Male 345 lb 4/9/2010 Canada
Primary
Concomitant
Toe Amputation Hospitalization 65 Male 4/22/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 10/20/2009 69 Male 174 lb 4/26/2010 Physician Chile
Primary
Secondary
Concomitant
Procedural Pain Other Serious 10/1/2009 60 Female 4/21/2010 United States
Primary
Secondary
Pain In Extremity Other Serious 60 Female 4/28/2010 Consumer United States
Primary
Secondary
Pain In Extremity Other Serious Female 4/29/2010 Consumer United States
Primary
Secondary
Cardiac Operation Other Serious 8/1/2009 74 Male 220 lb 5/6/2010 United States
Primary
Concomitant
Nausea Male 250 lb 6/3/2010 United States
Primary
Concomitant
Chest Pain Other Serious 5/1/2010 64 Female 184 lb 6/4/2010 Other Health Professional Canada
Primary
Concomitant
Toe Amputation Hospitalization 65 Male 6/18/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 4/23/2008 54 Male 209 lb 6/18/2010 Lawyer United States
Primary
Concomitant
Hypoglycaemia Hospitalization 4/1/2010 71 Male 7/9/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pulse Absent Required Intervention 4/26/2010 47 Male 187 lb 7/7/2010 Other Health Professional United States
Primary
Concomitant
Meningioma Hospitalization 3/28/2010 67 Male 220 lb 7/13/2010 Physician Germany
Primary
Concomitant
Hypoglycaemia Hospitalization 4/1/2010 71 Male 7/19/2010 Other Health Professional France
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 1/1/2008 77 Female 132 lb 7/19/2010 Consumer Brazil
Primary
Concomitant
Pharyngeal Oedema Other Serious 3/1/2008 50 Male 328 lb 7/22/2010 Lawyer United States
Primary
Concomitant
Hiccups 5/9/2008 52 Female 186 lb 7/22/2010 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 1/1/2009 61 Female 7/31/2010 Pharmacist United States
Primary
Concomitant
Rash Other Serious 81 Female 8/11/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 58 Male 8/12/2010 Other Health Professional United States
Primary
Concomitant
Lactic Acidosis 8/7/2010 40 Female 277 lb 8/11/2010 Pharmacist United States
Primary
Concomitant
Pruritus Male 280 lb 8/16/2010 Consumer United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 6/25/2010 72 Female 8/17/2010 Physician United States
Primary
Concomitant
Sepsis Hospitalization Male 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/18/2008 54 Male 209 lb 8/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Constipation 7/1/2010 70 Female 249 lb 8/26/2010 Consumer United States
Primary
Concomitant
Myalgia 9/1/2008 Male 8/27/2010 United States
Primary
Concomitant
Muscular Weakness 7/30/2009 74 Male 232 lb 8/27/2010 United States
Primary
Concomitant
Nausea 3/1/2009 74 Male 183 lb 8/27/2010 United States
Primary
Concomitant
Blood Glucose Increased 1/1/2008 47 Male 184 lb 8/27/2010 United States
Primary
Concomitant
Skin Burning Sensation Male 186 lb 8/27/2010 United States
Primary
Concomitant
Flushing 10/1/2009 50 Female 142 lb 8/28/2010 United States
Primary
Concomitant
Sensory Disturbance 1/1/1999 61 Male 190 lb 8/28/2010 United States
Primary
Concomitant
Flushing 12/1/2009 65 Female 133 lb 8/28/2010 United States
Primary
Concomitant
Wrist Fracture 11/1/2009 71 Female 210 lb 8/28/2010 United States
Primary
Concomitant
Flushing 11/1/2009 62 Female 179 lb 8/28/2010 United States
Primary
Concomitant
Musculoskeletal Discomfort 12/8/2009 62 Male 222 lb 8/28/2010 United States
Primary
Concomitant
Flushing 1/1/2008 70 Male 257 lb 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation Male 215 lb 8/28/2010 United States
Primary
Concomitant
Sinusitis 8/1/2009 66 Female 218 lb 8/28/2010 United States
Primary
Concomitant
Blood Glucose Decreased 2/4/2010 67 Male 268 lb 8/28/2010 United States
Primary
Concomitant
Nausea Male 228 lb 8/28/2010 United States
Primary
Concomitant
Flushing 4/1/2009 58 Female 185 lb 8/28/2010 United States
Primary
Concomitant
Dizziness 2/12/2010 64 Female 157 lb 8/28/2010 United States
Primary
Concomitant
Flushing Female 182 lb 8/28/2010 United States
Primary
Concomitant
Pruritus 2/1/2010 59 Female 8/28/2010 United States
Primary
Concomitant
Palpitations Female 240 lb 8/28/2010 United States
Primary
Concomitant
Flushing 3/15/2010 66 Female 140 lb 8/28/2010 United States
Primary
Concomitant
Flushing 3/25/2010 66 Male 266 lb 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation 4/20/2010 42 Male 8/28/2010 United States
Primary
Concomitant
Paraesthesia 4/21/2010 61 Female 278 lb 8/29/2010 Consumer United States
Primary
Concomitant
Blood Triglycerides Increased 4/1/2010 69 Male 8/29/2010 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 3/1/2010 51 Male 210 lb 8/29/2010 Consumer United States
Primary
Concomitant
Flushing 5/1/2010 66 Male 250 lb 8/29/2010 Consumer United States
Primary
Concomitant
Flushing Male 230 lb 8/29/2010 Consumer United States
Primary
Concomitant
Flushing Male 334 lb 8/29/2010 Consumer United States
Primary
Concomitant
Rash Macular 4/1/2010 61 Male 175 lb 8/29/2010 Consumer United States
Primary
Concomitant
Rash Macular 10/1/2009 60 Female 8/29/2010 Consumer United States
Primary
Concomitant
Pruritus 7/1/2010 74 Male 240 lb 8/29/2010 Consumer United States
Primary
Concomitant
Flushing Female 189 lb 8/29/2010 Consumer United States
Primary
Concomitant
Blood Glucose Increased Male 210 lb 8/29/2010 Consumer United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 5/1/2010 71 Female 8/30/2010 Physician United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 64 Male 424 lb 8/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Other Serious 8/3/2006 73 Male 9/1/2010 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/9/2010 71 Male 9/9/2010 Other Health Professional United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 6/25/2010 72 Female 9/9/2010 Physician United States
Primary
Concomitant
Drug Abuse Other Serious Male 9/9/2010 Pharmacist Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 12/11/2009 74 Male 146 lb 9/9/2010 Pharmacist United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 3/1/2008 50 Male 328 lb 9/15/2010 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 9/4/2010 66 Male 334 lb 9/14/2010 Physician United States
Primary
Secondary
Concomitant
Diarrhoea 11/17/2009 76 Male 9/18/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious Female 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/7/2010 58 Male 9/22/2010 Consumer Brazil
Primary
Secondary
Concomitant
Oropharyngeal Pain 8/12/2010 80 Female 9/23/2010 Consumer
Primary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 198 lb 9/27/2010 Physician Germany
Primary
Secondary
Concomitant

Drug Data