Carvedilol combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Acute Hospitalization 3/20/2003 Female 1/4/2006 Australia
Primary
Concomitant
Ventricular Dysfunction Life Threatening 8/30/2005 Male 139 lb 2/8/2006 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Ventricular Hypokinesia Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 61 Female 227 lb 2/7/2006 Physician South Africa
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/4/2006 Female 126 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Dizziness Other Serious 9/13/2005 64 Male 209 lb 4/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 159 lb 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Purpura Other Serious 4/5/2005 60 Male 9/5/2006 Other Health Professional Japan
Primary
Secondary
Patella Fracture Other Serious 7/15/2006 71 Female 7/2/2007 Consumer Italy
Primary
Concomitant
Joint Sprain Other Serious 1/29/2007 71 Female 7/20/2007 Consumer Italy
Primary
Concomitant
Pruritus Disability 1/1/2007 Male 8/16/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Granulocyte Count Increased Hospitalization 7/14/2007 64 Male 8/22/2007 Other Health Professional Denmark
Primary
Concomitant
Joint Sprain Other Serious 1/29/2007 71 Female 8/27/2007 Consumer Italy
Primary
Concomitant
Patella Fracture Other Serious 7/15/2006 71 Female 8/30/2007 Consumer Italy
Primary
Concomitant
Granulocyte Count Increased Hospitalization 7/14/2007 64 Male 8/31/2007 Other Health Professional Denmark
Primary
Concomitant
Pruritus Generalised Disability 3/20/2007 Male 9/14/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pruritus Generalised Disability 3/20/2007 Male 9/18/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pruritus Generalised Disability 3/20/2007 Male 9/27/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Arteriospasm Coronary Life Threatening 3/22/2007 77 Female 206 lb 11/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2006 83 Male 11/20/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 11/22/2007 81 Male 12/28/2007 United States
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 10/22/2007 65 Male 1/14/2008 Physician Spain
Primary
Secondary
Patella Fracture Other Serious 7/15/2006 71 Female 5/22/2008 Consumer Italy
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 56 Female 207 lb 7/15/2008 Consumer Turkey
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 9/1/2008 68 Female 10/17/2008 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 10/14/2008 71 Male 10/23/2008 Consumer
Primary
Concomitant
Completed Suicide Death 43 Male 1/28/2009 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 69 Female 1/21/2009 Other Health Professional Netherlands
Primary
Concomitant
Hypoglycaemia Other Serious 7/25/2008 73 Male 3/16/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Myopathy Other Serious 10/3/2008 66 Male 161 lb 5/22/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/8/2007 Female 6/4/2009 Consumer
Primary
Concomitant
Drug Interaction Hospitalization 83 Male 6/5/2009 Taiwan, Province Of China
Primary
Concomitant
Interacting
Myopathy Other Serious 10/3/2008 66 Male 161 lb 6/9/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Headache Hospitalization 2/25/2009 58 Male 6/15/2009 Physician Italy
Primary
Concomitant
Renal Failure Acute Other Serious 3/30/2009 66 Male 6/16/2009 Physician Italy
Primary
Concomitant
Renal Failure Acute Hospitalization 6/7/2009 60 Male 134 lb 6/30/2009 Pharmacist United States
Primary
Concomitant
Wound Other Serious 7/28/2009 69 Male 161 lb 8/6/2009 Consumer Brazil
Primary
Concomitant
Skin Burning Sensation Female 8/22/2009 United States
Primary
Concomitant
Death Death 8/8/2009 68 9/4/2009 Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Weight Increased 12/1/2000 50 Male 275 lb 9/23/2009 United States
Primary
Concomitant
Throat Irritation Other Serious 9/16/2009 77 Male 170 lb 9/30/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 9/25/2009 United States
Primary
Concomitant
Unemployment Hospitalization 1/20/2006 73 Male 163 lb 9/22/2009 United States
Primary
Concomitant
Condition Aggravated Death 8/8/2009 68 10/16/2009 Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Vomiting 2/26/2009 58 Male 1/4/2010 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/6/2010 46 Male 476 lb 1/8/2010 Pharmacist United States
Primary
Concomitant
Musculoskeletal Pain Hospitalization 11/8/2009 49 Male 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Interstitial Lung Disease Life Threatening 12/27/2009 61 Male 3/1/2010 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 11/16/2009 Male 3/3/2010 Consumer Brazil
Primary
Concomitant
Renal Failure Other Serious 10/1/2007 61 Male 214 lb 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2008 Male 162 lb 3/8/2010 Physician United States
Primary
Concomitant
Cardiac Failure Death 91 Male 176 lb 3/9/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Death Death 1/26/2010 81 Male 185 lb 3/5/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious Male 5/17/2010 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious Male 5/27/2010 Consumer United States
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 74 Male 5/27/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Interacting
Abdominal Pain Upper 80 Female 181 lb 5/27/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/2/2010 69 Female 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Sopor Other Serious 3/4/2010 77 Female 6/29/2010 Physician Italy
Primary
Secondary
Concomitant
Paraesthesia 1/1/2009 65 Male 145 lb 6/29/2010 Pharmacist United States
Primary
Concomitant
Tooth Extraction Other Serious 60 Female 6/23/2010 Consumer United States
Primary
Secondary
Fluid Retention 9/1/2009 60 Male 190 lb 9/14/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 10/9/2010 10/22/2010 Physician United States
Primary
Concomitant
Troponin Increased Other Serious 8/28/2009 55 Male 12/2/2010 Physician Australia
Primary
Concomitant
Renal Impairment Death 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 6/1/2010 71 Female 2/14/2011 Consumer Brazil
Primary
Concomitant
Cardiac Disorder Hospitalization 8/9/2010 68 Male 3/4/2011 Consumer Brazil
Primary
Secondary
Concomitant
Cholecystectomy Other Serious 1/1/2002 60 Female 170 lb 5/3/2011 Consumer United States
Primary
Concomitant
Tinnitus Other Serious 3/28/2011 57 Male 154 lb 5/17/2011 Pharmacist Japan
Primary
Concomitant
Coronary Artery Disease Other Serious 12/16/2010 69 Male 269 lb 6/30/2011 Physician United States
Primary
Secondary
Concomitant
Emotional Disorder Hospitalization 1/1/2009 69 Male 282 lb 7/21/2011 Consumer Brazil
Primary
Secondary
Concomitant
Ischaemic Cardiomyopathy Hospitalization 5/5/2011 75 Male 215 lb 8/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dysuria 1/1/2010 83 Male 8/29/2011 Consumer United States
Primary
Concomitant
Acute Myocardial Infarction Death 51 Female 9/19/2011 Physician China
Primary
Secondary
Concomitant
Cerebral Ischaemia Hospitalization 8/7/2010 64 Male 172 lb 9/29/2011 Physician Greece
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 5/19/2011 Female 9/27/2011 Physician United States
Primary
Concomitant
Ischaemic Stroke Death 6/17/2011 70 Female 154 lb 10/11/2011 Physician Chile
Primary
Concomitant
Syncope Hospitalization 1/18/2011 73 Male 189 lb 10/11/2011 Physician United States
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2011 81 Male 10/5/2011 Other Health Professional United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 12/1/2010 40 Female 10/14/2011 Other Health Professional United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 4/21/2011 65 Male 236 lb 10/17/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 51 Female 10/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Application Site Burn Other Serious Female 10/18/2011 Physician United States
Primary
Concomitant
Cerebral Ischaemia Hospitalization 1/1/2008 78 Male 163 lb 11/1/2011 Consumer Brazil
Primary
Secondary
Concomitant
Diarrhoea Disability 10/17/2011 74 Female 132 lb 11/3/2011 Other Health Professional Portugal
Primary
Concomitant
Cardiomegaly Hospitalization 12/2/2011 48 Male 179 lb 12/12/2011 Consumer Brazil
Primary
Concomitant
Cystitis Other Serious 11/22/2011 72 Female 176 lb 12/22/2011 Consumer Brazil
Primary
Concomitant
Anaemia Haemolytic Autoimmune Life Threatening 11/10/2011 80 Male 1/5/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2010 66 Male 1/10/2012 Physician United States
Primary
Secondary
Poisoning Death 1/1/2010 66 Male 1/11/2012 Physician United States
Primary
Secondary
Haemoglobin Decreased Hospitalization 9/29/2011 76 Male 1/18/2012 Consumer Germany
Primary
Secondary
Concomitant
Hypoxia Hospitalization Male 1/25/2012 Lawyer United States
Primary
Concomitant
Mental Status Changes Other Serious 7/11/2011 82 Female 3/8/2012 Physician United States
Primary
Secondary
Concomitant
Cognitive Disorder Other Serious 81 Female 3/16/2012 Other Health Professional Spain
Primary
Concomitant
Angina Pectoris Hospitalization 5/13/2011 70 Male 198 lb 3/16/2012 Physician Germany
Primary
Secondary
Concomitant
Anal Inflammation Other Serious 1/1/2010 76 Male 229 lb 3/28/2012 Consumer Brazil
Primary
Secondary
Concomitant
Bladder Transitional Cell Carcinoma Required Intervention 10/1/2011 75 Male 6/6/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/22/2011 72 Female 176 lb 6/20/2012 Consumer Brazil
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization Male 234 lb 6/22/2012 Other Health Professional United States
Primary
Concomitant
Pemphigoid Other Serious 75 Male 6/12/2012 Other Health Professional Greece
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 4/30/2012 71 Male 6/20/2012 Consumer United Kingdom
Primary
Concomitant
Cough 6/28/2012 56 Female 7/13/2012 Consumer United States
Primary
Concomitant
Hepatic Failure Hospitalization 3/6/2012 58 Female 179 lb 7/13/2012 Physician Hungary
Primary
Secondary
Concomitant
Chest Pain Hospitalization 8/17/2011 64 Male 7/16/2012 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Life Threatening 11/27/2011 62 Male 254 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged 1/1/2011 72 Male 218 lb 7/18/2012 Consumer United States
Primary
Concomitant
Interacting
Tongue Blistering 75 Female 7/18/2012 Physician United States
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 1/1/2004 67 Female 118 lb 7/19/2012 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/1/2008 76 Male 141 lb 7/19/2012 Physician Australia
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/16/2010 69 Male 269 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Vomiting Death 4/21/2012 84 Male 220 lb 7/20/2012 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 3/29/2012 72 Male 172 lb 7/22/2012 Physician United States
Primary
Secondary
Concomitant
Injury Other Serious Male 7/9/2012 Lawyer United States
Primary
Concomitant
Condition Aggravated Other Serious 4/2/2012 50 Female 7/26/2012 Other Health Professional United States
Primary
Concomitant
Haemothorax Hospitalization 6/18/2012 63 Male 225 lb 7/13/2012 United States
Primary
Concomitant
Blood Triglycerides Increased Death 6/28/2012 Female 95 lb 7/27/2012 Consumer Brazil
Primary
Concomitant
Blood Creatinine Increased Hospitalization 5/1/2012 68 Male 7/27/2012 Consumer Canada
Primary
Concomitant
Hyperhidrosis Other Serious 2/11/2012 47 Male 208 lb 7/31/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Speech Disorder Other Serious 7/31/2012 Other Health Professional United States
Primary
Secondary
Rhabdomyolysis Hospitalization 8/1/2012 Other Health Professional United States
Primary
Concomitant
Vertigo Hospitalization 5/10/2012 91 Female 7/12/2012 Physician Italy
Primary
Concomitant
Gangrene Hospitalization 4/11/2012 54 Male 270 lb 5/9/2012 Pharmacist United States
Primary
Secondary
Concomitant
Eructation 6/1/2012 65 Female 8/2/2012 Consumer United States
Primary
Secondary
Concomitant
Ocular Hyperaemia Male 180 lb 8/3/2012 Consumer United States
Primary
Concomitant
Muscle Spasms Female 195 lb 8/3/2012 Consumer United States
Primary
Concomitant
Feeling Hot 5/11/2011 66 Male 176 lb 8/3/2012 Consumer United States
Primary
Concomitant
Paraesthesia Male 8/3/2012 Consumer United States
Primary
Concomitant
Flushing 6/1/2010 57 Female 150 lb 8/3/2012 Consumer United States
Primary
Concomitant
Flushing Male 180 lb 8/3/2012 Consumer United States
Primary
Concomitant
Medication Residue 6/1/2011 51 Female 225 lb 8/3/2012 Consumer United States
Primary
Concomitant
Feeling Hot 9/2/2011 62 Female 132 lb 8/3/2012 Consumer United States
Primary
Concomitant
Abdominal Discomfort 7/9/2012 63 Male 216 lb 8/3/2012 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia 1/1/2010 56 Male 285 lb 8/3/2012 Consumer United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 4/1/2010 63 Male 323 lb 8/3/2012 Consumer United States
Primary
Concomitant
Diarrhoea Male 8/3/2012 Consumer United States
Primary
Concomitant
Blood Glucose Increased Male 217 lb 8/3/2012 Consumer United States
Primary
Concomitant
Blood Pressure Decreased 3/1/2012 55 Male 276 lb 8/3/2012 Consumer United States
Primary
Concomitant
Tooth Injury 4/1/2012 77 Male 8/6/2012 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/1/2012 54 Female 250 lb 8/7/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Cellulitis Hospitalization 7/29/2012 66 Female 355 lb 8/8/2012 Other Health Professional United States
Primary
Concomitant
Pain 1/1/2012 87 Male 8/8/2012 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 7/31/2012 74 Male 182 lb 8/8/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data