Carvedilol combined with Lansoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Deep Vein Thrombosis 11/30/2005 65 Female 1/1/2006 Physician Japan
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 5/15/2005 68 Male 218 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 2/28/2006 United Kingdom
Primary
Concomitant
Epistaxis Hospitalization 1/30/2006 87 Male 3/1/2006 Pharmacist Ireland
Primary
Concomitant
Catheter Site Haemorrhage Hospitalization 10/11/2004 65 Male 217 lb 12/21/2005 United States
Primary
Secondary
Concomitant
Coronary Artery Occlusion Hospitalization 1/1/2003 67 Female 230 lb 12/27/2005 Other Health Professional United States
Primary
Concomitant
Shunt Occlusion Other Serious 12/21/2005 56 Male 4/10/2006 Physician Japan
Primary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Paraesthesia Other Serious 6/14/2005 Female 4/27/2006 Physician Japan
Primary
Secondary
Concomitant
Sudden Death Death 2/6/2006 55 Female 168 lb 4/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Life Threatening 3/10/2006 71 Male 139 lb 5/16/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/10/2006 71 Male 139 lb 5/19/2006 Physician United Kingdom
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 12/7/2001 56 Male 6/13/2006 United States
Primary
Secondary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 8/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 73 Male 8/11/2006 Brazil
Primary
Concomitant
Wheezing Other Serious 69 Male 152 lb 8/18/2006 Pharmacist United Kingdom
Primary
Concomitant
Colon Cancer Metastatic Death 5/1/2006 Male 268 lb 9/6/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 9/6/2006 74 Male 10/25/2006 Physician Japan
Primary
Secondary
Hypoglycaemia Other Serious 7/20/2006 80 Male 11/2/2006 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 9/6/2006 74 Male 11/16/2006 Physician Japan
Primary
Secondary
Pulmonary Embolism Hospitalization 5/1/2006 Female 195 lb 11/22/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/10/2006 71 Male 139 lb 11/21/2006 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 5/26/2006 56 Male 11/6/2006 United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 2/14/2007 Male 2/22/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 8/17/2006 76 Female 3/7/2007 Consumer Italy
Primary
Concomitant
Thrombocytopenia Life Threatening 4/2/2007 67 Male 6/1/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/2/2007 67 Male 6/8/2007 Consumer United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Required Intervention 1/1/2007 48 Female 188 lb 6/13/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 4/2/2007 67 Male 7/11/2007 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/29/2006 65 Female 7/16/2007 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/1/2007 70 Male 154 lb 7/13/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/2/2007 67 Male 7/30/2007 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/29/2006 65 Female 8/8/2007 Other Health Professional Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/13/2007 66 Female 8/6/2007 Japan
Primary
Secondary
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/13/2007 71 Male 9/5/2007 Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/13/2007 66 Female 9/13/2007 Japan
Primary
Secondary
Muscle Spasms Other Serious 70 Male 187 lb 9/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Incorrect Dose Administered Other Serious 7/30/2007 76 Female 88 lb 10/16/2007 Physician Japan
Primary
Secondary
Concomitant
Treatment Noncompliance Life Threatening 10/11/2007 Male 145 lb 10/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Injection Site Pain 6/1/2007 Female 267 lb 12/14/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 4/2/2007 67 Male 3/17/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/2/2007 67 Male 3/27/2008 Consumer United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Life Threatening 4/2/2007 67 Male 3/28/2008 Consumer United States
Primary
Secondary
Concomitant
Intestinal Functional Disorder Hospitalization 4/1/2008 80 Male 4/8/2008 United Kingdom
Primary
Concomitant
Intestinal Functional Disorder Hospitalization 4/1/2008 80 Male 4/11/2008 United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 United States
Primary
Concomitant
Myocardial Ischaemia Life Threatening 8/30/2005 Male 139 lb 4/22/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/30/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/9/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/15/2008 United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 3/6/2008 80 Male 5/20/2008 United Kingdom
Primary
Concomitant
Left Ventricular Dysfunction Hospitalization 1/1/2004 80 Male 5/23/2008 United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 12/28/2007 54 Male 6/4/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/5/2008 Male 106 lb 6/4/2008 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased 2/21/2008 Female 134 lb 6/12/2008 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 4/1/2008 83 Male 6/16/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 4/5/2008 Male 106 lb 6/18/2008 Physician Japan
Primary
Concomitant
Arteriosclerosis Obliterans Other Serious 6/15/2007 83 Male 106 lb 6/20/2008 Physician Japan
Primary
Concomitant
Hyperkalaemia Life Threatening 12/28/2007 54 Male 6/23/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Vomiting Hospitalization 5/26/2008 60 Male 6/27/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 4/1/2008 83 Male 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 4/1/2008 83 Male 7/21/2008 Physician Japan
Primary
Secondary
Concomitant
Splenic Infarction Other Serious 2/1/2008 52 Male 170 lb 7/21/2008 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 4/1/2008 83 Male 7/25/2008 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Life Threatening 4/30/2008 55 Male 7/31/2008 Physician Japan
Primary
Concomitant
Gastric Ulcer Other Serious 6/5/2008 Female 8/14/2008 Other Health Professional Germany
Primary
Concomitant
Gastric Ulcer Other Serious 6/5/2008 Female 8/19/2008 Other Health Professional Germany
Primary
Concomitant
Platelet Count Decreased Life Threatening 4/1/2008 83 Male 8/21/2008 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Other Serious 6/5/2008 Female 8/22/2008 Consumer Germany
Primary
Concomitant
Flushing 12/6/2007 Male 186 lb 8/27/2008 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 6/2/2008 58 Male 8/29/2008 Physician Japan
Primary
Concomitant
Gastric Ulcer Other Serious 6/5/2008 76 Female 8/25/2008 Germany
Primary
Concomitant
Small Intestinal Haemorrhage Hospitalization 6/2/2008 58 Male 9/10/2008 Physician Japan
Primary
Concomitant
Hepatic Enzyme Increased 2/21/2008 Female 134 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Splenic Infarction Hospitalization 52 Male 9/17/2008 United States
Primary
Secondary
Malaise Required Intervention 10/13/2008 71 Male 11/3/2008 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 10/17/2008 26 Male 132 lb 11/4/2008 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 9/10/2008 78 Female 10/8/2008 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/29/2008 Female 184 lb 11/21/2008 Consumer United States
Primary
Concomitant
Paraesthesia 10/12/2008 Male 11/26/2008 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/29/2008 Female 184 lb 12/4/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 9/16/2008 85 Female 12/29/2008 Physician Japan
Primary
Secondary
Concomitant
Tenderness Hospitalization 9/24/2008 62 Female 97 lb 1/5/2009 Physician Japan
Primary
Concomitant
Pancreatic Carcinoma Life Threatening 9/5/2008 Male 132 lb 1/27/2009 Other Health Professional Japan
Primary
Concomitant
General Physical Health Deterioration Other Serious 1/13/2009 85 Male 1/30/2009 Consumer Germany
Primary
Concomitant
Somnolence Other Serious 11/21/2007 59 Female 95 lb 2/3/2009 Physician Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 1/13/2009 85 Male 2/11/2009 Pharmacist Germany
Primary
Concomitant
Staphylococcal Infection Other Serious 10/21/2006 71 Female 2/13/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased 57 Male 2/16/2009 Pharmacist United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 1/30/2009 78 Male 2/27/2009 Physician Italy
Primary
Concomitant
Platelet Count Increased Other Serious 1/11/2009 3/13/2009 Physician United Kingdom
Primary
Concomitant
Graft Ischaemia Hospitalization 9/14/2008 35 Female 130 lb 3/11/2009 Physician Italy
Primary
Secondary
Concomitant
Epilepsy Other Serious 1/30/2009 78 Male 3/18/2009 Physician Italy
Primary
Concomitant
Epilepsy Other Serious 1/30/2009 78 Male 3/20/2009 Physician Italy
Primary
Concomitant
Platelet Count Decreased Other Serious 2/11/2009 4/9/2009 Physician United Kingdom
Primary
Concomitant
Lethargy Required Intervention 3/2/2009 63 Female 190 lb 4/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Death 1/1/2009 90 Female 5/6/2009 Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 10/24/2008 60 Male 5/5/2009 Japan
Primary
Concomitant
Off Label Use Life Threatening 10/24/2008 60 Male 5/15/2009 Japan
Primary
Concomitant
Sepsis Death 3/13/2009 Female 6/10/2009 Physician Japan
Primary
Concomitant
Sepsis Death 3/13/2009 85 Female 6/15/2009 Japan
Primary
Secondary
Concomitant
Hypoglycaemia Required Intervention 3/31/2009 Male 200 lb 4/11/2009 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 6/25/2002 49 Male 192 lb 7/14/2009 United States
Primary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 10/24/2008 60 Male 7/20/2009 Japan
Primary
Concomitant
Hyperkalaemia Life Threatening 4/8/2009 84 Male 7/21/2009 Japan
Primary
Secondary
Renal Failure Acute Other Serious 9/16/2008 86 Female 7/28/2009 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 5/18/2009 58 Male 7/27/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancreatic Carcinoma Life Threatening 10/7/2007 Male 132 lb 8/4/2009 Other Health Professional Japan
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 11/8/2008 81 Male 132 lb 9/2/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/13/2009 72 Male 8/28/2009 Physician Japan
Primary
Concomitant
Incorrect Dose Administered 8/7/2007 Female 140 lb 9/11/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 7/30/2009 Male 9/14/2009 Consumer Japan
Primary
Secondary
Concomitant
Prothrombin Time Abnormal Hospitalization 8/20/2009 87 Female 9/23/2009 Physician United Kingdom
Primary
Concomitant
Respiration Abnormal Required Intervention 7/24/2009 75 Female 134 lb 7/27/2009 United States
Primary
Concomitant
Mental Impairment Hospitalization Male 10/9/2009 Pharmacist United Kingdom
Primary
Concomitant
Rash Pruritic Hospitalization 52 Male 9/18/2009 Other Health Professional United States
Primary
Secondary
Drug Hypersensitivity Hospitalization 52 Male 9/18/2009 Other Health Professional United States
Primary
Secondary
Rash Pruritic Hospitalization 52 Male 9/18/2009 United States
Primary
Secondary
Rash Pruritic Hospitalization 52 Male 9/18/2009 United States
Primary
Secondary
Septic Shock Hospitalization 2/10/2009 50 Male 109 lb 10/19/2009 Physician Japan
Primary
Concomitant
Small Intestinal Haemorrhage Required Intervention 8/29/2009 80 Male 269 lb 9/21/2009 Pharmacist United States
Primary
Concomitant
Septic Shock Hospitalization 2/10/2009 50 Male 109 lb 10/27/2009 Physician Japan
Primary
Concomitant
Death Hospitalization 9/4/2009 Female 11/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/16/2009 Male 203 lb 11/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 9/4/2009 Female 11/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pancreatic Carcinoma Life Threatening 8/26/2008 85 Male 132 lb 12/15/2009 Other Health Professional Japan
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2004 67 Female 12/29/2009 Other Health Professional Italy
Primary
Concomitant
Haemoglobin Decreased Hospitalization 10/7/2009 Female 161 lb 10/8/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/6/2009 59 Male 1/5/2010 Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/1/2003 68 Female 2/10/2010 Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/6/2009 59 Male 3/5/2010 Japan
Primary
Secondary
Concomitant
Blood Glucose Decreased Other Serious 1/19/2010 86 Female 160 lb 1/19/2010 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Other Serious 1/21/2010 73 Male 176 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Large Intestine Perforation Hospitalization 9/4/2009 Female 134 lb 3/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 7/31/2009 51 Male 168 lb 3/26/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 9/10/2008 79 Female 3/26/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2009 Female 117 lb 3/26/2010 Other Health Professional Japan
Primary
Concomitant
Vertigo Other Serious 4/1/2009 Female 3/24/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 5/15/2009 67 Female 89 lb 3/29/2010 Physician Japan
Primary
Secondary
Concomitant
Nephropathy Hospitalization 2/17/2010 62 Female 4/6/2010 Other Health Professional Japan
Primary
Concomitant
International Normalised Ratio Increased Other Serious 11/20/2009 67 Male 119 lb 4/8/2010 Physician Japan
Primary
Secondary
Concomitant
Interacting
Renal Impairment Other Serious 1/1/2009 73 Female 117 lb 4/8/2010 Other Health Professional Japan
Primary
Concomitant
Ileus Other Serious 4/1/2010 68 Male 4/8/2010 Other Health Professional Japan
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 2/26/2010 69 Male 4/8/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/22/2002 49 Male 192 lb 4/16/2010 United States
Primary
Concomitant

Drug Data