Carvedilol combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Treatment Noncompliance Required Intervention 8/30/2005 Female 9/2/2005 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Pneumonia Hospitalization 12/19/2005 77 Female 115 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Coronary Artery Occlusion Hospitalization 1/1/2003 67 Female 230 lb 12/27/2005 Other Health Professional United States
Primary
Concomitant
Rash Pruritic Other Serious 1/30/2005 75 Female 165 lb 12/21/2005 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2004 60 Male 3/17/2006 Consumer Brazil
Primary
Concomitant
Gastrointestinal Haemorrhage Required Intervention 4/18/2006 77 Male 134 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/1/2004 60 Male 4/25/2006 Brazil
Primary
Concomitant
Urinary Tract Infection Death 1/25/2006 72 Female 150 lb 5/1/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Syncope Required Intervention 12/1/2005 77 Female 12/2/2005 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Life Threatening 12/6/2001 82 Female 5/26/2006 Physician Finland
Primary
Secondary
Concomitant
Syncope Hospitalization 6/14/2006 83 Male 6/23/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 6/14/2006 69 Male 7/13/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/5/2001 77 Male 7/21/2006 United States
Primary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 9/11/2006 Other Health Professional Netherlands
Primary
Concomitant
Intracranial Aneurysm Hospitalization 6/21/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Sudden Death Death Male 9/14/2006 Physician Japan
Primary
Concomitant
Dyspnoea Hospitalization 3/7/2005 79 Female 9/15/2006 Consumer Japan
Primary
Concomitant
Visual Field Defect Other Serious 6/1/2006 58 Male 9/20/2006 Japan
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 9/29/2006 Other Health Professional Netherlands
Primary
Concomitant
Liver Disorder Hospitalization 7/22/2006 82 Male 10/9/2006 Physician Japan
Primary
Secondary
Death Death 67 Female 162 lb 1/30/2006 Physician United States
Primary
Concomitant
Liver Disorder Hospitalization 7/22/2006 82 Male 10/18/2006 Physician Japan
Primary
Secondary
Thrombocytopenia Required Intervention 8/23/2006 85 Male 160 lb 10/10/2006 Other Health Professional United States
Primary
Concomitant
Nodal Rhythm Hospitalization 9/25/2006 80 Female 10/16/2006 Physician Poland
Primary
Secondary
Concomitant
Sudden Death Hospitalization 7/4/2005 Male 11/13/2006 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 12/4/2006 Female 176 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
Renal Impairment Other Serious 12/1/2006 79 Male 1/18/2007 Physician China
Primary
Concomitant
Rash Other Serious 8/23/2006 52 Male 329 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Chest Pain Other Serious 12/22/2006 1/30/2007 Consumer United Kingdom
Primary
Concomitant
Ventricular Tachycardia Life Threatening 12/8/2005 73 Male 1/30/2007 United Kingdom
Primary
Concomitant
Nausea Hospitalization 9/25/2006 80 Female 2/12/2007 Poland
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 1/1/2006 50 Female 12/15/2006 Canada
Primary
Concomitant
Renal Impairment Other Serious 12/1/2006 79 Male 3/6/2007 Physician China
Primary
Concomitant
Weight Decreased Hospitalization 87 Male 3/13/2007
Primary
Secondary
Concomitant
Melaena Hospitalization 1/22/2007 61 Male 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2003 87 Male 5/9/2007 Physician United States
Primary
Concomitant
Melaena Hospitalization 8/1/2005 Male 203 lb 6/19/2007 Physician Italy
Primary
Concomitant
Pyrexia Hospitalization 3/27/2007 74 Male 157 lb 7/27/2007 Greece
Primary
Concomitant
Granulocyte Count Increased Hospitalization 7/14/2007 64 Male 8/22/2007 Other Health Professional Denmark
Primary
Concomitant
Granulocyte Count Increased Hospitalization 7/14/2007 64 Male 8/31/2007 Other Health Professional Denmark
Primary
Concomitant
Incorrect Dose Administered Other Serious 7/30/2007 76 Female 88 lb 10/16/2007 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective 57 Male 11/13/2007 Consumer United States
Primary
Concomitant
Orthostatic Hypotension 73 Male 11/13/2007 Consumer United States
Primary
Concomitant
Malaise Life Threatening 7/26/2007 78 Male 11/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 9/7/2007 Female 176 lb 12/20/2007 Greece
Primary
Concomitant
Rectal Cancer Hospitalization 9/7/2007 Female 176 lb 12/28/2007 Greece
Primary
Concomitant
Rectal Cancer Hospitalization 9/7/2007 Female 176 lb 1/10/2008 Greece
Primary
Concomitant
Colorectal Cancer Hospitalization 9/7/2007 Female 176 lb 1/14/2008 Greece
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 60 Male 290 lb 11/29/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 73 Male 120 lb 12/3/2007 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/25/2008 Female 152 lb 2/14/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased 1/1/2007 61 Male 175 lb 12/5/2007 Physician United States
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 3/11/2008 Other Health Professional Netherlands
Primary
Concomitant
Nutritional Condition Abnormal Other Serious 3/1/2008 65 Male 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 3/27/2008 Other Health Professional Netherlands
Primary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 United States
Primary
Concomitant
Myocardial Ischaemia Life Threatening 8/30/2005 Male 139 lb 4/22/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/30/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/9/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/15/2008 United States
Primary
Concomitant
Renal Failure Other Serious 2/8/2008 Male 110 lb 5/23/2008 Physician Japan
Primary
Secondary
Concomitant
Interacting
Myocardial Ischaemia Hospitalization 3/6/2008 80 Male 5/20/2008 United Kingdom
Primary
Concomitant
Left Ventricular Dysfunction Hospitalization 1/1/2004 80 Male 5/23/2008 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Visual Midline Shift Syndrome Hospitalization 5/6/2008 Female 131 lb 7/1/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 8/18/2008 Other Health Professional Netherlands
Primary
Concomitant
Pruritus 5/3/2008 77 Male 8/27/2008 United States
Primary
Concomitant
Rash Macular 7/11/2008 Female 8/29/2008 United States
Primary
Concomitant
Speech Disorder Other Serious 7/19/2008 60 Female 9/1/2008 Portugal
Primary
Concomitant
Decubitus Ulcer Hospitalization 4/11/2008 80 Male 9/10/2008 Japan
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 9/19/2008 Other Health Professional Netherlands
Primary
Concomitant
Myocardial Infarction Other Serious 12/9/2006 79 Male 10/15/2008 Japan
Primary
Concomitant
Tongue Oedema Hospitalization 1/25/2008 Female 152 lb 10/27/2008 Physician United States
Primary
Concomitant
Drug Ineffective 6/4/2008 86 Female 11/13/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 12/9/2006 79 Male 11/20/2008 Japan
Primary
Concomitant
Urinary Incontinence Life Threatening 11/11/2008 Female 127 lb 11/17/2008 Pharmacist United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 9/22/2008 82 Female 11/24/2008 Physician Germany
Primary
Secondary
Concomitant
Intestinal Ischaemia Hospitalization 10/31/2008 75 Male 11/19/2008 Physician Japan
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 11/1/2008 78 Male 175 lb 12/8/2008 Consumer United States
Primary
Concomitant
Catheter Site Infection 10/12/2008 Female 169 lb 12/12/2008 United States
Primary
Concomitant
Large Intestinal Ulcer Haemorrhage Required Intervention 10/31/2008 75 Male 12/12/2008 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 11/14/2008 67 Male 12/12/2008 Japan
Primary
Concomitant
Product Quality Issue Death 5/1/2008 65 Male 225 lb 12/15/2008 Consumer United States
Primary
Concomitant
Splenomegaly Other Serious 1/20/2008 12/22/2008 Other Health Professional Singapore
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 3/1/2008 60 Female 130 lb 12/17/2008 Consumer United States
Primary
Concomitant
Large Intestinal Ulcer Haemorrhage Required Intervention 10/31/2008 75 Male 12/29/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/20/2008 1/30/2009 Other Health Professional Singapore
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 11/14/2008 67 Male 1/29/2009 Consumer Japan
Primary
Concomitant
Colon Cancer Life Threatening 12/10/2008 68 Male 2/12/2009 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2004 Male 209 lb 2/13/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/31/2009 44 Female 117 lb 2/17/2009 Consumer Brazil
Primary
Secondary
Concomitant
Product Quality Issue Death 11/29/2008 92 Male 2/19/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 5/1/2008 74 Female 2/20/2009 Consumer United States
Primary
Concomitant
Sudden Death Death 1/6/2009 Male 220 lb 3/6/2009 United States
Primary
Concomitant
Chest Pain Hospitalization 3/14/2009 4/2/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Chest Pain Hospitalization 3/14/2009 4/15/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Transfusion-related Acute Lung Injury Other Serious 3/14/2009 Female 189 lb 4/17/2009 Other Health Professional United States
Primary
Concomitant
Chest Pain Hospitalization 3/14/2009 4/24/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 9/22/2008 82 5/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Product Quality Issue Death 5/1/2008 65 Male 225 lb 5/11/2009 Consumer United States
Primary
Concomitant
Renal Failure Death 1/12/2008 69 Female 139 lb 5/15/2009 Physician Japan
Primary
Concomitant
Speech Disorder Male 5/27/2009 United States
Primary
Concomitant
Presyncope Hospitalization 3/31/2009 Male 6/2/2009 Physician Netherlands
Primary
Secondary
Renal Failure Death 1/12/2008 69 Female 139 lb 6/1/2009 Physician Japan
Primary
Concomitant
Chest Pain Hospitalization 3/14/2009 73 6/9/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 65 Male 154 lb 6/17/2009 Portugal
Primary
Concomitant
Pulmonary Congestion Other Serious 65 Male 157 lb 6/25/2009 Physician Portugal
Primary
Concomitant
International Normalised Ratio Decreased 10/22/2008 82 Female 161 lb 7/22/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 10/22/2008 82 Female 161 lb 7/22/2009 Consumer United States
Primary
Concomitant
Atrial Fibrillation Other Serious 10/1/2008 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 7/30/2009 61 Male 8/17/2009 Japan
Primary
Secondary
Concomitant
Flushing 7/1/2008 Male 8/21/2009 United States
Primary
Concomitant
Headache 8/19/2008 Female 8/21/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 7/30/2009 61 9/11/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/30/2009 Male 9/14/2009 Consumer Japan
Primary
Secondary
Concomitant
Unevaluable Event Disability 7/1/2009 75 Female 142 lb 9/8/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/9/2009 75 Male 199 lb 9/16/2009 Physician United States
Primary
Secondary
Concomitant
Urticaria 2/15/2009 94 Female 212 lb 7/30/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 7/30/2009 61 10/9/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased 9/1/2009 58 Male 12/11/2009 Consumer United States
Primary
Concomitant
Peritonitis Bacterial Other Serious 3/5/2009 76 Male 168 lb 11/3/2009 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/9/2009 Male 158 lb 12/17/2009 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/9/2009 Male 160 lb 12/23/2009 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Cerebrovascular Accident Hospitalization 12/9/2009 Male 162 lb 12/28/2009 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Cerebrovascular Accident Hospitalization 12/9/2009 Male 162 lb 1/5/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Cerebrovascular Accident Hospitalization 12/9/2009 Male 162 lb 1/7/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Suicide Attempt Life Threatening 12/26/2009 60 Male 1/13/2010 Physician Denmark
Primary
Secondary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 Male 162 lb 1/20/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Embolic Stroke Other Serious 12/18/2007 65 Male 159 lb 2/2/2010 Lawyer United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 Male 161 lb 2/8/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 Male 161 lb 2/8/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Staphylococcal Infection Hospitalization 6/10/2009 50 Male 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening 12/26/2009 60 Male 2/10/2010 Physician Denmark
Primary
Secondary
Concomitant
Vertigo Hospitalization 79 Male 142 lb 1/27/2010 Lawyer United States
Primary
Concomitant
Vasculitis Other Serious 1/31/2010 66 Male 325 lb 2/8/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Death Death 11/5/2009 Female 3/5/2010 Physician Canada
Primary
Concomitant
Visual Impairment Hospitalization 11/19/2008 59 Male 311 lb 3/3/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/26/2007 79 Male 3/16/2010 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Death 11/26/2008 38 Male 226 lb 3/15/2010 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Spinal Column Stenosis Disability 1/11/2010 60 Male 4/22/2010 Other Health Professional Japan
Primary
Concomitant

Drug Data