Carvedilol combined with Folic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Vomiting Death 12/30/2005 58 Male 180 lb 1/19/2006 United States
Primary
Concomitant
Vasculitis Death 9/27/2005 Female 214 lb 2/7/2006 Italy
Primary
Concomitant
Ventricular Tachycardia Hospitalization 74 Male 185 lb 2/21/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 3/1/2006 44 Male 134 lb 4/11/2006 Pharmacist United States
Primary
Concomitant
Vasculitis Death 9/27/2005 Female 214 lb 4/18/2006 Other Health Professional Italy
Primary
Concomitant
Thrombocytopenia Hospitalization 3/7/2006 76 Male 134 lb 4/14/2006 Pharmacist United States
Primary
Concomitant
Hyperphosphataemia Other Serious 4/20/2006 Female 5/11/2006 Physician Spain
Primary
Concomitant
Vomiting Other Serious 3/24/2005 Female 77 lb 5/17/2006 Physician Portugal
Primary
Concomitant
Hyperphosphataemia Other Serious 4/20/2006 Female 5/22/2006 Physician Spain
Primary
Concomitant
Malaise 9/1/2005 76 Male 3/13/2006 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/7/2005 83 Male 165 lb 7/17/2006 Denmark
Primary
Secondary
Concomitant
Myalgia Other Serious 1/1/2004 62 Male 7/20/2006 Germany
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/5/2001 77 Male 7/21/2006 United States
Primary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Prothrombin Time Shortened Death 5/7/2006 66 Male 154 lb 8/14/2006 Physician Spain
Primary
Secondary
Concomitant
Neuroendocrine Carcinoma Of The Skin Other Serious 5/1/2005 83 Female 121 lb 9/26/2006 Physician Israel
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 11/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Neuroendocrine Carcinoma Of The Skin Other Serious 5/1/2005 Female 120 lb 12/5/2006 Physician Israel
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 12/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Urine Output Increased Other Serious 6/13/2006 89 Male 183 lb 12/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Rash Other Serious 8/23/2006 52 Male 329 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 12/26/2006 71 Female 150 lb 1/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/26/2006 71 Female 150 lb 2/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/26/2006 71 Female 150 lb 2/12/2007 Consumer United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 12/28/2006 71 Female 150 lb 2/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 2/14/2007 Male 2/22/2007 Other Health Professional United States
Primary
Concomitant
Headache Other Serious 9/1/2006 Male 175 lb 12/6/2006 Pharmacist United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 2/5/2007 Female 157 lb 3/1/2007 Other Health Professional Czech Republic
Primary
Concomitant
Fall Life Threatening 2/11/2007 74 Male 3/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 10/1/2006 Male 148 lb 3/22/2007 Physician Venezuela
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2006 72 Male 3/30/2007 Physician New Zealand
Primary
Secondary
Concomitant
Melaena Hospitalization 1/22/2007 61 Male 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 10/1/2006 Male 148 lb 4/6/2007 Physician Venezuela
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 4/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/30/2007 82 Male 176 lb 5/10/2007 Physician Greece
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 5/11/2007 Other Health Professional France
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 9/1/2006 51 Male 170 lb 12/13/2006 Consumer United States
Primary
Concomitant
Rash Maculo-papular Hospitalization 1/1/2007 Male 181 lb 5/24/2007 Other Health Professional Canada
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/1/2006 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 5/2/2004 Male 226 lb 5/25/2007 Consumer United States
Primary
Concomitant
Nausea Hospitalization 5/2/2007 Male 226 lb 6/7/2007 Physician United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 6/6/2007 54 Female 215 lb 6/19/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 5/2/2007 Male 226 lb 6/25/2007 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 4/19/2007 83 Male 6/27/2007 Physician Switzerland
Primary
Secondary
Concomitant
Nausea Hospitalization 5/1/2007 Male 226 lb 6/27/2007 Physician United States
Primary
Concomitant
Skin Lesion Other Serious 4/1/2007 Male 7/16/2007 Physician Australia
Primary
Concomitant
Skin Lesion Other Serious 4/1/2007 Male 7/23/2007 Physician Australia
Primary
Concomitant
Skin Lesion Other Serious 4/1/2007 Male 7/27/2007 Physician Australia
Primary
Concomitant
Sepsis Hospitalization 6/4/2007 60 Female 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 3/9/2007 Female 142 lb 8/9/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 3/9/2007 Female 142 lb 8/9/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2006 72 Male 8/16/2007 Physician New Zealand
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 12/18/2006 Female 143 lb 8/23/2007 Physician Argentina
Primary
Concomitant
Urine Leukocyte Esterase Positive Hospitalization 6/4/2007 60 Female 8/23/2007 Physician United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 4/1/2007 Male 10/1/2007 Physician Australia
Primary
Concomitant
Septic Shock Hospitalization 9/20/2007 Male 133 lb 10/2/2007 Greece
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 10/9/2007 Physician Australia
Primary
Secondary
Concomitant
Vasculitis Hospitalization 9/27/2005 Female 214 lb 10/11/2007 Other Health Professional Italy
Primary
Concomitant
Transplant Rejection Other Serious 12/18/2006 Female 143 lb 10/17/2007 Physician Argentina
Primary
Concomitant
Septic Shock Hospitalization 9/20/2007 Male 133 lb 11/2/2007 Greece
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 12/1/2007 63 Male 1/14/2008 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/19/2007 63 Male 294 lb 1/31/2008 United States
Primary
Concomitant
Malaise 1/22/2008 55 Male 344 lb 2/16/2008 United States
Primary
Concomitant
Cardiomyopathy Other Serious 12/7/2006 46 Female 1/17/2008 Physician United States
Primary
Concomitant
Scrotal Swelling Hospitalization 1/13/2008 Male 172 lb 2/25/2008 Greece
Primary
Concomitant
White Blood Cell Count Decreased 1/1/2007 61 Male 175 lb 12/5/2007 Physician United States
Primary
Concomitant
Renal Failure Other Serious Female 2/28/2008 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/1/2007 82 Female 3/7/2008 Consumer United States
Primary
Concomitant
Nutritional Condition Abnormal Other Serious 3/1/2008 65 Male 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 12/24/2007 82 Male 1/8/2008 Pharmacist United States
Primary
Concomitant
Skin Hyperpigmentation Hospitalization 65 Male 3/25/2008 Physician Serbia
Primary
Concomitant
Skin Lesion Other Serious 4/1/2007 Male 4/21/2008 Physician Australia
Primary
Concomitant
Vasculitis Hospitalization 9/27/2005 Female 214 lb 4/21/2008 Other Health Professional Italy
Primary
Concomitant
Vasculitis Hospitalization 9/27/2005 Female 214 lb 5/1/2008 Other Health Professional Italy
Primary
Concomitant
Respiratory Failure Other Serious 10/22/2007 72 Male 128 lb 5/13/2008 Physician Portugal
Primary
Concomitant
Scrotal Swelling Hospitalization 1/13/2008 Male 172 lb 5/22/2008 Greece
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 5/2/2008 69 Female 5/23/2008 Physician Switzerland
Primary
Concomitant
Renal Failure Other Serious 2/8/2008 Male 110 lb 5/23/2008 Physician Japan
Primary
Secondary
Concomitant
Interacting
Pathological Gambling Hospitalization 1/1/2002 Male 218 lb 5/27/2008 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 10/22/2007 72 Male 128 lb 5/30/2008 Physician Portugal
Primary
Concomitant
Loss Of Consciousness Hospitalization 5/27/2008 Male 6/6/2008 Physician Japan
Primary
Concomitant
Serum Ferritin Increased Other Serious 1/1/2006 Female 6/11/2008 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Psychomotor Hyperactivity Hospitalization 4/28/2008 71 Male 6/2/2008 United States
Primary
Concomitant
Visual Disturbance 1/1/2008 Male 190 lb 6/12/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/19/2008 Female 190 lb 6/12/2008 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 12/7/2006 Female 7/3/2008 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/30/2007 82 Male 176 lb 7/14/2008 Physician Greece
Primary
Concomitant
Unresponsive To Stimuli Death 6/2/2008 Female 220 lb 7/9/2008 United States
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Other Serious 3/1/2007 87 Female 139 lb 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Sinus Arrest Other Serious 5/7/2008 75 Male 134 lb 7/23/2008 Greece
Primary
Concomitant
No Therapeutic Response Hospitalization 4/29/2008 82 Female 143 lb 7/23/2008 Consumer United States
Primary
Concomitant
Flushing 5/31/2008 Female 8/27/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 4/1/2008 Female 265 lb 9/13/2008 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/13/2008 69 Male 165 lb 9/19/2008 Greece
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/13/2008 69 Male 165 lb 10/1/2008 Greece
Primary
Concomitant
Muscle Spasms 4/1/2008 55 Female 278 lb 10/3/2008 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 9/1/2008 76 Female 10/9/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Viral Infection Hospitalization 1/1/2006 70 Male 195 lb 10/3/2008 Lawyer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/19/2008 Male 184 lb 10/13/2008 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2008 76 Female 174 lb 10/23/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 7/9/2008 Male 10/27/2008 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 1/1/1989 Female 165 lb 11/3/2008 Consumer United States
Primary
Concomitant
Pollakiuria Hospitalization 1/1/2008 76 Female 174 lb 11/11/2008 Consumer United States
Primary
Concomitant
Feeling Cold 1/1/2005 58 Male 11/13/2008 Consumer United States
Primary
Secondary
Concomitant
Ventricular Internal Diameter Abnormal Other Serious 11 Male 11/21/2008 Other Health Professional United Arab Emirates
Primary
Concomitant
Pruritus Female 11/26/2008 United States
Primary
Concomitant
Pruritus Male 11/26/2008 United States
Primary
Concomitant
Pruritus 10/29/2008 Female 11/26/2008 United States
Primary
Secondary
Concomitant
Flushing Male 11/26/2008 United States
Primary
Concomitant
Paraesthesia Other Serious 4/1/2007 52 Male 12/4/2008 Physician Switzerland
Primary
Secondary
Concomitant
Somnolence 6/20/2008 Female 175 lb 12/4/2008 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 9/1/2007 Female 12/8/2008 Other Health Professional United States
Primary
Concomitant
Hypotension 11/3/2008 68 Male 12/9/2008 Consumer
Primary
Concomitant
Flatulence 9/21/2008 71 Female 153 lb 12/18/2008 United States
Primary
Concomitant
Coronary Arterial Stent Insertion Hospitalization 10/1/2007 Male 1/2/2009 Belgium
Primary
Concomitant
Renal Failure Chronic Death 12/6/2008 81 Female 132 lb 1/14/2009 Consumer Brazil
Primary
Secondary
Concomitant
Flushing Hospitalization 1/1/2006 Female 123 lb 1/28/2009 Physician United States
Primary
Concomitant
Left Ventricular Dysfunction Hospitalization 45 Male 199 lb 1/24/2009 United States
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 45 Male 199 lb 2/4/2009 Lawyer United States
Primary
Concomitant
Palpitations Other Serious 11/23/2007 79 Female 2/16/2009 Consumer United States
Primary
Concomitant
Skin Burning Sensation Other Serious 66 Male 2/17/2009 Pharmacist United States
Primary
Concomitant
Skin Necrosis Other Serious 66 Male 2/18/2009 Pharmacist United States
Primary
Concomitant
Palpitations Other Serious 11/23/2008 79 Female 2/19/2009 Consumer United States
Primary
Concomitant
Pulmonary Congestion Death 25 Male 3/4/2009 Other Health Professional Philippines
Primary
Concomitant
Vaginal Infection Other Serious Female 135 lb 3/14/2009 Physician United States
Primary
Concomitant
Scar Death 11/20/2008 85 Male 123 lb 3/6/2009 Switzerland
Primary
Secondary
Concomitant
Pulmonary Embolism Death 9/1/2008 76 Female 3/27/2009 Other Health Professional Brazil
Primary
Secondary
Concomitant
Shock Death 11/20/2008 85 Male 123 lb 3/27/2009 Switzerland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 67 Male 4/3/2009 United States
Primary
Concomitant
Delirium Other Serious 3/27/2009 Female 4/20/2009 Consumer Italy
Primary
Concomitant
Syncope Hospitalization 3/13/2009 83 Male 4/22/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pain In Extremity Required Intervention 11/12/2008 40 Male 311 lb 12/31/2008 Pharmacist United States
Primary
Concomitant
Lethargy Required Intervention 3/2/2009 63 Female 190 lb 4/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Joint Stiffness 1/1/2008 5/4/2009 Consumer United States
Primary
Concomitant
Haemorrhoids Other Serious 12/29/2008 Female 112 lb 5/13/2009 Physician United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 9/10/2008 42 Male 5/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 67 Male 5/15/2009 United States
Primary
Concomitant
Joint Stiffness 1/1/2008 Male 5/22/2009 Consumer United States
Primary
Concomitant
Pain Hospitalization 5/5/2009 28 Male 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 12/29/2008 Female 112 lb 6/10/2009 Physician United States
Primary
Secondary
Concomitant
Kidney Transplant Rejection Hospitalization 5/5/2009 28 Male 6/9/2009 Physician United States
Primary
Secondary
Concomitant
Paraesthesia 9/1/2008 Female 175 lb 6/11/2009 United States
Primary
Concomitant
Gout 10/1/2001 Male 217 lb 6/16/2009 Physician United States
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 6/1/2009 Female 6/19/2009 Physician United States
Primary
Concomitant
Chest Pain Hospitalization Female 6/25/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 219 lb 6/29/2009 Consumer United States
Primary
Concomitant

Drug Data