Carvedilol combined with Famotidine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/17/2005 63 Female 2/3/2006 Japan
Primary
Concomitant
Vomiting Other Serious 12/2/2005 73 Male 2/9/2006 Japan
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/28/2006 75 Female 2/13/2006 Japan
Primary
Concomitant
Weight Decreased Hospitalization 1/28/2006 75 Female 2/24/2006 Japan
Primary
Concomitant
Shock Hospitalization 6/27/1998 63 Male 3/20/2006 Physician Japan
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/28/2006 75 Female 3/10/2006 Japan
Primary
Concomitant
Weight Decreased Hospitalization 1/16/2006 81 Female 4/13/2006 Czech Republic
Primary
Secondary
Concomitant
Vision Blurred Other Serious 4/18/2006 71 Male 4/28/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/16/2006 81 Female 5/1/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 4/12/2006 56 Male 132 lb 4/28/2006 Japan
Primary
Concomitant
Vomiting Other Serious 3/1/2006 Male 6/15/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 12/7/2001 56 Male 6/13/2006 United States
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Bradycardia Other Serious 3/1/2006 Male 7/10/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/6/2004 Female 8/7/2006 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 6/10/2005 75 Male 10/6/2006 Physician Japan
Primary
Concomitant
Sudden Death Death 7/4/2005 67 Male 10/31/2006 Physician Japan
Primary
Concomitant
Drug Administration Error Hospitalization 10/13/2006 Male 11/2/2006 Consumer
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 10/21/2006 66 Male 11/17/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/6/2004 Female 12/7/2006 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/12/2006 Female 223 lb 12/19/2006 Pharmacist United States
Primary
Concomitant
Headache Other Serious 9/1/2006 Male 175 lb 12/6/2006 Pharmacist United States
Primary
Concomitant
Superinfection Life Threatening 1/23/2007 80 Female 3/15/2007 Physician Japan
Primary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 5/25/2007 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 6/9/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/23/2007 40 Female 137 lb 6/12/2007 Pharmacist United States
Primary
Concomitant
Hepatic Function Abnormal Other Serious 6/21/2007 68 Male 7/3/2007 Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 7/11/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Life Threatening 1/23/2007 80 Female 90 lb 7/6/2007 Physician Japan
Primary
Concomitant
Urine Colour Abnormal Other Serious 5/2/2007 68 Male 7/16/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 3/17/2007 68 Female 185 lb 7/25/2007 United States
Primary
Concomitant
Tachycardia Death 3/9/2005 52 Male 8/9/2007 Physician Japan
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 3/9/2007 Female 142 lb 8/9/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 3/9/2007 Female 142 lb 8/9/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/16/2006 81 Female 9/7/2007 United States
Primary
Secondary
Concomitant
Urinary Bladder Haemorrhage Life Threatening 1/23/2007 80 Female 90 lb 11/5/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 9/7/2007 63 Male 165 lb 11/26/2007 Pharmacist United States
Primary
Concomitant
Renal Impairment Life Threatening 4/21/2007 40 Male 176 lb 12/28/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death 71 Female 1/11/2008 Other Health Professional United States
Primary
Secondary
Multiple Drug Overdose Death 71 Female 1/14/2008 Physician United States
Primary
Secondary
Accidental Exposure Death 1/1/2006 71 Female 1/18/2008 United States
Primary
Secondary
Mucosal Inflammation Hospitalization 8/8/2007 Female 1/25/2008 Physician United States
Primary
Secondary
Concomitant
Poisoning Death 71 Female 1/22/2008 Physician United States
Primary
Secondary
Death Death 1/1/2006 71 Female 1/25/2008 Physician United States
Primary
Secondary
Poisoning Death 71 Female 1/31/2008 Physician United States
Primary
Secondary
Lung Disorder Hospitalization 1/23/2008 74 Female 2/20/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Death Death 1/1/2006 71 Female 2/14/2008 Physician United States
Primary
Secondary
Urticaria Required Intervention 2/1/2008 62 Male 262 lb 2/29/2008 Pharmacist United States
Primary
Concomitant
Sudden Death Death 12/5/2007 48 Male 148 lb 4/3/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 4/19/2008 72 Female 119 lb 6/5/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7/14/2005 78 Male 104 lb 7/2/2008 Physician Japan
Primary
Concomitant
Pruritus Other Serious 11/4/2005 77 Male 216 lb 7/21/2008 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 7/23/2008 Physician Japan
Primary
Secondary
Concomitant
Intentional Overdose Hospitalization 6/30/2008 63 Female 7/25/2008 Physician Japan
Primary
Secondary
Concomitant
Musculoskeletal Pain 6/1/2008 Female 8/29/2008 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 9/25/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/9/2007 Male 11/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/9/2007 Male 11/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fatigue 72 Female 11/13/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2008 64 Male 227 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
Left Ventricular Dysfunction Hospitalization 45 Male 199 lb 1/24/2009 United States
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 45 Male 199 lb 2/4/2009 Lawyer United States
Primary
Concomitant
Sepsis Life Threatening 1/23/2009 Male 218 lb 3/10/2009 Other Health Professional
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7/14/2005 78 Male 104 lb 4/10/2009 Physician Japan
Primary
Concomitant
Unresponsive To Stimuli Other Serious 8/1/2007 5/1/2009 Physician United States
Primary
Concomitant
Joint Stiffness 1/1/2008 5/4/2009 Consumer United States
Primary
Concomitant
Resorption Bone Increased Other Serious 2/12/2009 84 Female 4/30/2009 Physician Japan
Primary
Concomitant
Renal Failure Death 1/12/2008 69 Female 139 lb 5/15/2009 Physician Japan
Primary
Concomitant
Unresponsive To Stimuli Other Serious 8/1/2007 Male 5/22/2009 Physician United States
Primary
Concomitant
Joint Stiffness 1/1/2008 Male 5/22/2009 Consumer United States
Primary
Concomitant
Renal Failure Death 1/12/2008 69 Female 139 lb 6/1/2009 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 6/19/2009 80 Female 7/6/2009 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/30/2009 Male 218 lb 7/9/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/25/2002 49 Male 192 lb 7/14/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 6/19/2009 80 Female 7/20/2009 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 6/19/2009 80 Female 8/7/2009 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 7/30/2009 61 Male 8/17/2009 Japan
Primary
Secondary
Concomitant
Pruritus 8/22/2009 United States
Primary
Concomitant
Liver Disorder Life Threatening 9/19/2006 58 Female 101 lb 8/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Toxicity Death 8/29/2009 Physician United States
Primary
Secondary
Renal Failure Hospitalization 7/30/2009 61 9/11/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/30/2009 Male 9/14/2009 Consumer Japan
Primary
Secondary
Concomitant
Liver Disorder Life Threatening 9/19/2006 58 Female 101 lb 9/15/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/30/2009 Male 218 lb 9/24/2009 Physician United States
Primary
Secondary
Concomitant
Liver Disorder Life Threatening 9/4/2006 58 Female 101 lb 10/1/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Kidney Transplant Rejection Other Serious 8/7/2009 Male 10/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/30/2009 61 10/9/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Generalised Other Serious 58 Female 101 lb 10/13/2009 Consumer Japan
Primary
Secondary
Kidney Transplant Rejection Other Serious 8/7/2009 Male 10/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Jaundice Other Serious 9/19/2006 58 Female 11/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Other Serious 9/19/2006 58 Female 101 lb 11/25/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/30/2009 Male 218 lb 12/30/2009 Physician United States
Primary
Secondary
Concomitant
Infarction Life Threatening 1/9/2010 Male 95 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/31/2009 91 Male 148 lb 1/5/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 2/4/2010 Lawyer United States
Primary
Concomitant
Septic Shock Hospitalization 1/30/2009 Male 218 lb 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 1/30/2009 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Occlusion Other Serious 1/1/2008 78 Female 135 lb 2/22/2010 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Infarction Life Threatening 1/9/2010 Male 95 lb 3/8/2010 Consumer United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 6/18/2009 67 Male 159 lb 3/12/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization Male 320 lb 3/26/2010 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 2/24/2009 Female 3/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/15/2010 70 Male 153 lb 3/29/2010 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 3/11/2010 80 Male 3/31/2010 Physician Japan
Primary
Secondary
Concomitant
Tinnitus Other Serious 3/12/2010 77 Male 4/7/2010 Physician Japan
Primary
Concomitant
Sinus Bradycardia Life Threatening 1/21/2010 77 Male 104 lb 4/7/2010 Pharmacist Japan
Primary
Concomitant
Cardiac Failure Congestive Hospitalization Male 320 lb 4/7/2010 Physician United States
Primary
Concomitant
Spinal Compression Fracture Hospitalization 6/18/2009 67 Male 159 lb 4/8/2010 Physician Japan
Primary
Secondary
Concomitant
Genital Pain Hospitalization 11/22/2009 64 Male 116 lb 4/9/2010 Japan
Primary
Concomitant
Weight Increased Hospitalization 5/22/2002 49 Male 192 lb 4/16/2010 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Spinal Column Stenosis Disability 1/11/2010 60 Male 4/22/2010 Other Health Professional Japan
Primary
Concomitant
Eosinophil Count Increased Hospitalization 2/20/2010 82 Male 108 lb 4/30/2010 Physician Japan
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/13/2009 66 Male 171 lb 5/6/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 5/7/2010 Other Health Professional United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/5/2010 48 Male 5/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/13/2009 66 Male 171 lb 5/18/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/13/2009 66 Male 171 lb 5/26/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/30/2009 64 Male 218 lb 6/9/2010 Physician United States
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 5/5/2010 48 Male 6/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 5/19/2010 6/15/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 6/10/2010 89 Male 161 lb 6/15/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 6/22/2010 Lawyer United States
Primary
Concomitant
Septic Shock Hospitalization 1/30/2009 64 Male 220 lb 6/22/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 68 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Septic Shock Life Threatening 1/30/2009 6/25/2010 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Male 265 lb 6/29/2010 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious Female 6/30/2010 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 1/30/2009 64 Male 220 lb 7/6/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 1/30/2009 7/9/2010 Physician United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 7/13/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Tenderness Other Serious 4/2/2008 58 Male 258 lb 8/18/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 187 lb 8/19/2010 Other Health Professional United States
Primary
Concomitant
Sensory Disturbance 1/1/1999 61 Male 190 lb 8/28/2010 United States
Primary
Concomitant
Pruritus Male 181 lb 8/28/2010 United States
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/1/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/28/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/13/2009 66 Male 171 lb 9/30/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 4/2/2008 58 Male 258 lb 10/11/2010 Lawyer United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 10/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant

Drug Data