Carvedilol combined with Eplerenone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Chest Pain Hospitalization 49 Male 7/19/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 3/4/2007 73 Male 5/2/2007 Greece
Primary
Concomitant
Cardiac Arrest Death 4/28/2007 Female 5/10/2007 Australia
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/1/2006 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 10/30/2007 Female 200 lb 12/19/2007 Greece
Primary
Concomitant
Diarrhoea Hospitalization 9/7/2007 Female 176 lb 12/20/2007 Greece
Primary
Concomitant
Rectal Cancer Hospitalization 9/7/2007 Female 176 lb 12/28/2007 Greece
Primary
Concomitant
Rectal Cancer Hospitalization 9/7/2007 Female 176 lb 1/10/2008 Greece
Primary
Concomitant
Colorectal Cancer Hospitalization 9/7/2007 Female 176 lb 1/14/2008 Greece
Primary
Concomitant
Hypercalcaemia Other Serious 10/30/2007 Female 200 lb 2/8/2008 Greece
Primary
Concomitant
Cardiomyopathy Other Serious 12/7/2006 46 Female 1/17/2008 Physician United States
Primary
Concomitant
Agranulocytosis Hospitalization 1/11/2008 Male 120 lb 3/6/2008 Physician Japan
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 1/11/2008 Male 120 lb 3/26/2008 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 4/25/2008 Female 85 lb 6/9/2008 Physician Japan
Primary
Secondary
Concomitant
Jaundice Other Serious 5/14/2008 Male 144 lb 6/30/2008 Physician Japan
Primary
Secondary
Concomitant
Myocarditis Death 40 Male 10/27/2008 Physician Germany
Primary
Concomitant
Anaphylactic Shock Hospitalization 1/1/2008 12/22/2008 Other Health Professional Spain
Primary
Concomitant
Anaphylactic Shock Hospitalization 3/13/2008 1/28/2009 Other Health Professional Spain
Primary
Concomitant
Renal Failure Acute Other Serious 1/20/2008 1/30/2009 Other Health Professional Singapore
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 1/31/2009 80 Male 4/28/2009 Spain
Primary
Secondary
Upper Respiratory Tract Inflammation Hospitalization 3/4/2007 73 Male 8/17/2009 Greece
Primary
Concomitant
Flushing 10/1/2008 Male 8/22/2009 United States
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 4/16/2009 79 Male 125 lb 5/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Hospitalization 4/16/2009 79 Male 125 lb 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 60 Male 6/30/2010 Physician Australia
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/16/2009 59 Female 185 lb 8/10/2010 Physician United States
Primary
Concomitant
Overdose Hospitalization 4/1/2010 80 Male 181 lb 8/24/2010 Physician Czech Republic
Primary
Secondary
Concomitant
Pruritus Male 181 lb 8/28/2010 United States
Primary
Concomitant
Blood Glucose Increased Male 250 lb 8/29/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Life Threatening 8/12/2010 87 Male 178 lb 9/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 9/3/2010 70 Male 190 lb 9/15/2010 Physician Sweden
Primary
Secondary
Concomitant
Duodenal Ulcer Haemorrhage Hospitalization 6/21/2010 55 Male 9/17/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/12/2010 87 Male 179 lb 9/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 9/23/2010 United States
Primary
Concomitant
Drug Interaction Other Serious 6/30/2010 56 Male 184 lb 9/28/2010 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Death 9/23/2010 74 Male 187 lb 10/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Hospitalization 10/23/2010 77 Male 176 lb 12/13/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/22/2008 40 Female 159 lb 12/13/2010 Physician Japan
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 2/26/2011 71 Male 3/1/2011 Physician India
Primary
Concomitant
Activated Partial Thromboplastin Time Abnormal 2/7/2011 83 Male 3/4/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 2/17/2011 60 Male 271 lb 3/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cholecystitis Hospitalization 2/26/2011 71 Male 121 lb 4/21/2011 Physician India
Primary
Concomitant
Haemoptysis Hospitalization 4/16/2011 57 Male 154 lb 6/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 4/16/2011 57 Male 154 lb 6/2/2011 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Gouty Arthritis Hospitalization 1/27/2009 71 Male 137 lb 7/5/2011 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 7/6/2011 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 6/7/2011 86 Male 7/11/2011 Other Health Professional Japan
Primary
Concomitant
Psoriatic Arthropathy Other Serious 4/1/2010 80 Male 181 lb 7/12/2011 Physician Czech Republic
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/28/2011 78 Male 132 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Fluid Overload Hospitalization 6/11/2011 69 Male 163 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/28/2011 78 Male 132 lb 7/27/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 8/10/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebellar Haemorrhage Hospitalization 6/18/2011 61 Male 128 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebellar Haemorrhage Hospitalization 6/18/2011 61 Male 128 lb 8/24/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Other Serious 6/28/2011 78 Female 99 lb 8/30/2011 Physician Japan
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 7/15/2011 59 Male 186 lb 8/30/2011 Other Health Professional Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 77 Male 9/13/2011 Consumer United States
Primary
Concomitant
Conjunctival Hyperaemia Other Serious 8/12/2011 79 Male 9/16/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 9/28/2011 Physician Japan
Primary
Secondary
Concomitant
Conjunctival Hyperaemia Other Serious 8/4/2011 79 Male 141 lb 10/4/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 10/6/2011 Physician Japan
Primary
Secondary
Concomitant
Abasia Other Serious 8/1/2011 77 Male 10/10/2011 Pharmacist Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 9/1/2011 77 Male 10/13/2011 Consumer United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 6/10/2011 86 Male 10/18/2011 Other Health Professional Japan
Primary
Concomitant
Conjunctival Hyperaemia Other Serious 8/4/2011 79 Male 141 lb 10/19/2011 Physician Japan
Primary
Concomitant
Muscular Weakness Other Serious 9/20/2011 77 Male 11/4/2011 Pharmacist Japan
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 69 Male 10/20/2011 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 69 Male 11/14/2011 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 11/18/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Pulmonary Oedema Hospitalization 11/3/2011 66 Male 11/23/2011 Physician Portugal
Primary
Concomitant
Weight Decreased Life Threatening 3/30/2011 66 Male 181 lb 12/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Disease Progression Other Serious 11/10/2011 78 Female 181 lb 12/5/2011 Physician Argentina
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 3/19/2009 79 Male 130 lb 12/5/2011 Physician Japan
Primary
Concomitant
Rash Other Serious 10/24/2011 78 Male 128 lb 12/6/2011 Physician Japan
Primary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 12/12/2011 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 69 Male 12/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Other Serious 69 Male 12/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 69 Male 12/15/2011 Other Health Professional United States
Primary
Concomitant
Benign Prostatic Hyperplasia Hospitalization 69 Male 12/13/2011 Physician United States
Primary
Concomitant
Toxicity To Various Agents Hospitalization 3/22/2011 66 Male 181 lb 12/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 12/26/2011 Physician Japan
Primary
Secondary
Concomitant
Fall Hospitalization 12/1/2011 73 Male 1/6/2012 Consumer United States
Primary
Concomitant
Urinary Retention Hospitalization 69 Male 1/5/2012 Physician United States
Primary
Concomitant
Toxicity To Various Agents Hospitalization 3/22/2011 66 Male 181 lb 1/18/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 10/29/2011 54 Male 154 lb 1/16/2012 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/14/2011 47 Male 198 lb 1/30/2012 Physician Japan
Primary
Concomitant
Oedema Peripheral Other Serious 6/16/2010 77 Female 128 lb 2/1/2012 Physician Japan
Primary
Concomitant
Interacting
Acute Pulmonary Oedema Hospitalization 11/3/2011 66 Male 2/2/2012 Physician Portugal
Primary
Concomitant
Cardiac Failure Other Serious 69 2/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 7/25/2011 57 Female 159 lb 2/23/2012 Physician Netherlands
Primary
Concomitant
Cerebral Infarction Hospitalization 2/17/2012 91 Female 2/28/2012 Physician Japan
Primary
Concomitant
Somnolence Other Serious 2/7/2012 81 Male 3/5/2012 Pharmacist Japan
Primary
Concomitant
Snoring Other Serious 2/7/2012 81 Male 3/5/2012 Pharmacist Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 2/20/2012 65 Male 3/1/2012 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 2/17/2012 91 Female 3/9/2012 Physician Japan
Primary
Concomitant
Cerebral Infarction Disability 2/28/2012 78 Male 109 lb 3/12/2012 Physician Japan
Primary
Secondary
Heart Injury Other Serious 23 Female 3/13/2012 Other Health Professional Poland
Primary
Concomitant
Aortic Valve Incompetence Other Serious 23 Female 3/13/2012 Other Health Professional Poland
Primary
Concomitant
Rhabdomyolysis Death 11/10/2011 75 Male 132 lb 3/14/2012 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 2/28/2012 78 Male 109 lb 3/19/2012 Physician Japan
Primary
Secondary
Oedema Peripheral Other Serious 6/16/2010 77 Female 128 lb 3/20/2012 Physician Japan
Primary
Concomitant
Interacting
Cardiac Failure Chronic Hospitalization 2/17/2012 60 Male 3/18/2012 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 2/28/2012 78 Male 109 lb 3/28/2012 Physician Japan
Primary
Secondary
Multi-organ Failure Death 11/10/2011 75 Male 132 lb 3/30/2012 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 11/10/2011 75 Male 132 lb 3/30/2012 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/16/2012 64 Male 159 lb 4/5/2012 Physician Spain
Primary
Concomitant
Respiratory Tract Infection Hospitalization 7/25/2011 57 Female 159 lb 4/12/2012 Physician Netherlands
Primary
Concomitant
Gastroenteritis Death 11/10/2011 75 Male 132 lb 4/11/2012 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 11/10/2011 75 Male 132 lb 4/19/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 3/16/2012 68 Male 111 lb 4/20/2012 Physician Japan
Primary
Concomitant
Pneumonia Death 1/12/2012 64 Male 159 lb 4/26/2012 Physician Spain
Primary
Concomitant
Pneumothorax Hospitalization 3/16/2012 68 Male 111 lb 5/3/2012 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Death 4/12/2011 70 Male 5/7/2012 Physician Japan
Primary
Secondary
Concomitant
Hypotension Hospitalization 5/1/2011 51 Male 5/10/2012 Physician Spain
Primary
Concomitant
Interacting
Renal Failure Other Serious 5/7/2011 51 Male 5/16/2012 Physician Spain
Primary
Concomitant
Interacting
Hypotension Hospitalization 5/1/2011 51 Male 5/18/2012 Physician Spain
Primary
Concomitant
Interacting
Cardiac Failure Life Threatening 4/1/2012 5/18/2012 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Death 4/1/2012 5/24/2012 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 5/30/2012 79 Female 6/4/2012 Physician Japan
Primary
Secondary
Concomitant
Atrial Flutter Other Serious 1/20/2006 77 Male 5/9/2012 Physician United States
Primary
Concomitant
Blood Alkaline Phosphatase Increased Hospitalization 79 Male 6/5/2012 Pharmacist United Kingdom
Primary
Concomitant
Protein Total Increased Hospitalization 79 Male 6/8/2012 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Death 4/1/2012 6/12/2012 Physician Japan
Primary
Concomitant
Retinal Ischaemia Disability 82 Male 6/22/2012 Physician Brazil
Primary
Concomitant
Blood Urea Increased Hospitalization 12/14/2011 83 Male 101 lb 6/8/2012 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 6/8/2012 60 Male 209 lb 6/27/2012 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 6/5/2012 69 Female 140 lb 6/28/2012 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 6/5/2012 69 Female 140 lb 6/20/2012 Other Health Professional
Primary
Concomitant
Haemoptysis Hospitalization 12/8/2011 77 Male 221 lb 6/28/2012 Physician United States
Primary
Concomitant
Depressed Level Of Consciousness Life Threatening 3/30/2012 6/29/2012 Physician Japan
Primary
Concomitant
Haemoptysis Hospitalization 12/8/2011 77 Male 221 lb 6/29/2012 Physician United States
Primary
Concomitant
Interacting
Anuria Life Threatening 5/1/2012 81 Male 133 lb 7/5/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/30/2012 79 Female 128 lb 7/10/2012 Physician Japan
Primary
Secondary
Concomitant
Paresis Hospitalization 10/14/2010 82 Female 110 lb 7/11/2012 Physician Japan
Primary
Concomitant
Blood Pressure Diastolic Decreased Hospitalization 10/14/2010 82 Female 110 lb 7/13/2012 Physician Japan
Primary
Concomitant
Blood Potassium Increased Other Serious 5/1/2012 81 Male 133 lb 7/18/2012 Physician Japan
Primary
Secondary
Concomitant
Cholangitis Hospitalization 1/28/2011 78 Male 132 lb 7/20/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Urea Increased Other Serious 6/27/2012 56 Male 123 lb 7/6/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/30/2012 79 Female 128 lb 7/27/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Other Serious 5/1/2012 81 Male 7/13/2012 Japan
Primary
Secondary
Concomitant
Pruritus 246 lb 8/3/2012 Consumer United States
Primary
Concomitant
Blood Test Abnormal Other Serious 1/1/2012 74 Male 236 lb 8/10/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Dysuria Other Serious 1/28/2011 78 Male 132 lb 8/14/2012 Physician Japan
Primary
Secondary
Concomitant
Nodal Rhythm Hospitalization 5/1/2012 81 Male 7/27/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 12/14/2011 83 Male 101 lb 7/27/2012 Physician Japan
Primary
Secondary
Concomitant
Cardiac Amyloidosis Life Threatening 3/30/2012 8/17/2012 Physician Japan
Primary
Secondary
Concomitant
Cardiac Amyloidosis Death 4/25/2012 60 Female 112 lb 8/22/2012 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2012 Male 236 lb 11/7/2012 Pharmacist Us
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 12/15/2011 62 Male 173 lb 10/30/2012 Physician Es
Primary
Secondary
Concomitant

Drug Data