Carvedilol combined with Digoxin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Acute Hospitalization 3/20/2003 Female 1/4/2006 Australia
Primary
Concomitant
Vomiting Life Threatening 3/4/2004 79 Female 1/10/2006 Consumer Australia
Primary
Secondary
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 5/15/2005 68 Male 218 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Nausea Other Serious 40 Male 218 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Required Intervention 8/30/2005 Female 9/2/2005 United States
Primary
Concomitant
Electromechanical Dissociation Life Threatening 9/12/2005 Male 9/23/2005 United States
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 9/18/2005 Male 9/20/2005 United States
Primary
Concomitant
Somnolence Required Intervention 12/18/2005 78 Male 166 lb 12/21/2005 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Hyperaldosteronism Hospitalization 12/28/2004 73 Female 121 lb 2/3/2006 Consumer France
Primary
Secondary
Concomitant
Malaise Other Serious 12/18/2005 57 Female 2/9/2006 Consumer United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 60 2/13/2006 Consumer Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 70 Male 2/7/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 12/20/2005 74 Male 187 lb 2/16/2006 Czech Republic
Primary
Secondary
Concomitant
Stress Hospitalization 1/1/2001 52 Male 326 lb 2/24/2006 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Cardiogenic Shock Other Serious 10/9/2005 82 Female 2/17/2006 Physician Greece
Primary
Concomitant
Hepatitis Toxic Other Serious 10/18/2005 77 Male 3/2/2006 Physician Spain
Primary
Concomitant
Weight Decreased Other Serious 64 Male 2/28/2006 Israel
Primary
Concomitant
Hypertension Required Intervention 11/1/2003 49 Male 3/8/2006 Physician United States
Primary
Secondary
Concomitant
Catheter Site Haemorrhage Hospitalization 10/11/2004 65 Male 217 lb 12/21/2005 United States
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 1/30/2005 75 Female 165 lb 12/21/2005 Consumer United States
Primary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Shock Hospitalization 6/27/1998 63 Male 3/20/2006 Physician Japan
Primary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Cardiogenic Shock Other Serious 10/9/2005 82 Female 3/27/2006 Other Health Professional Greece
Primary
Concomitant
White Blood Cell Count Increased Death 9/9/2004 73 Male 3/31/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/4/2006 Female 126 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 2/9/2006 82 Male 3/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 11/16/2005 29 Male 4/19/2006 Physician Australia
Primary
Concomitant
Vomiting Other Serious 4/1/2002 70 Male 4/27/2006 Canada
Primary
Secondary
Concomitant
Death Death 4/22/2006 88 Male 5/8/2006 United States
Primary
Concomitant
Syncope Required Intervention 12/1/2005 77 Female 12/2/2005 Pharmacist United States
Primary
Concomitant
Hyperphosphataemia Other Serious 4/20/2006 Female 5/11/2006 Physician Spain
Primary
Concomitant
Weight Increased Hospitalization 10/27/2004 47 Male 243 lb 5/10/2006 Other Health Professional United States
Primary
Concomitant
Hyperphosphataemia Other Serious 4/20/2006 Female 5/22/2006 Physician Spain
Primary
Concomitant
Mitral Valve Incompetence Hospitalization 4/1/2003 57 Male 5/31/2006 Taiwan, Province Of China
Primary
Concomitant
Procedural Hypotension Required Intervention 6/16/2005 80 Female 5/16/2006 Pharmacist United States
Primary
Secondary
Hypothyroidism Life Threatening 6/19/2005 53 Male 242 lb 6/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 7/5/2005 58 Male 201 lb 6/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 3/2/2006 56 Male 6/26/2006 Physician Netherlands
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Systemic Candida Other Serious 5/1/2006 78 Female 7/5/2006 Physician Japan
Primary
Concomitant
Rash Other Serious 5/12/2005 81 Male 7/21/2006 Consumer Australia
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/5/2001 77 Male 7/21/2006 United States
Primary
Concomitant
Cardiac Failure Other Serious 3/13/2006 69 Male 190 lb 7/26/2006 Physician Argentina
Primary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 53 Male 8/12/2006 Physician United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 11/7/2005 33 Female 8/15/2006 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/26/2006 82 Female 8/24/2006 United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 6/9/2006 64 Male 199 lb 6/9/2006 United States
Primary
Concomitant
Treatment Noncompliance Required Intervention 5/3/2006 67 Female 8/16/2006 Physician United States
Primary
Concomitant
Prothrombin Time Shortened Death 5/7/2006 66 Male 154 lb 8/14/2006 Physician Spain
Primary
Secondary
Concomitant
Hypoglycaemic Coma Death 6/12/2006 49 Male 8/24/2006 United States
Primary
Concomitant
Dyspnoea Hospitalization 6/20/2006 89 Female 9/1/2006 Consumer Switzerland
Primary
Secondary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/14/2006 75 Female 9/5/2006 Other Health Professional Netherlands
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 9/11/2006 Other Health Professional Netherlands
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 9/13/2006 Physician United States
Primary
Concomitant
Intracranial Aneurysm Hospitalization 6/21/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Sudden Death Death Male 9/14/2006 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 7/10/2006 79 Male 9/19/2006 Physician Japan
Primary
Concomitant
Dizziness Hospitalization 4/18/2006 Female 5/1/2006 Pharmacist United States
Primary
Secondary
Malaise Life Threatening 7/10/2006 79 Male 9/28/2006 Physician Japan
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 9/29/2006 Other Health Professional Netherlands
Primary
Concomitant
Infusion Related Reaction Other Serious 9/12/2006 1 Female 15 lb 9/22/2006 Physician Brazil
Primary
Concomitant
Cardiac Failure Acute Hospitalization 8/11/2006 75 Female 133 lb 10/6/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 9/1/2004 75 Male 10/10/2006 Physician Japan
Primary
Concomitant
Hypoglycaemia Life Threatening 4/7/2006 Female 115 lb 10/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 67 Female 162 lb 1/30/2006 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 52 Female 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 75 Female 133 lb 10/10/2006 Pharmacist United States
Primary
Concomitant
Torsade De Pointes Other Serious 10/2/2006 78 Male 10/12/2006 Physician Japan
Primary
Secondary
Renal Failure Hospitalization 10/15/2005 79 Female 10/27/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2005 66 Male 10/25/2006 Physician Lebanon
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/5/2006 65 Female 110 lb 10/26/2006 Physician Japan
Primary
Concomitant
Torsade De Pointes Other Serious 10/2/2006 78 Male 10/30/2006 Physician Japan
Primary
Secondary
Surgery Hospitalization 7/12/2005 70 Male 11/7/2006 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 11/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Sudden Death Hospitalization 7/4/2005 Male 11/13/2006 Physician Japan
Primary
Concomitant
Myoglobin Blood Increased Other Serious 7/31/2006 68 Female 11/22/2006 Consumer France
Primary
Concomitant
Torsade De Pointes Other Serious 10/1/2006 78 Male 11/17/2006 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Death 5/2/2006 71 Female 250 lb 11/17/2006 United States
Primary
Concomitant
Visual Acuity Reduced Life Threatening 72 Unknown 114 lb 11/21/2006 Japan
Primary
Secondary
Oedema Peripheral Other Serious 11/11/2006 73 Male 11/22/2006 Greece
Primary
Concomitant
Skin Necrosis Hospitalization 7/1/2003 75 Female 11/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/6/2006 84 Male 12/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 10/1/2006 78 Male 12/6/2006 Physician Japan
Primary
Secondary
Concomitant
Benign Neoplasm Hospitalization 4/14/2005 92 Female 12/18/2006 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 12/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Swelling Life Threatening 7/23/2006 73 Female 174 lb 12/15/2006 Pharmacist United States
Primary
Concomitant
Hypoxia Hospitalization 7/23/2006 81 9/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/5/2006 65 Female 110 lb 12/18/2006 Physician Japan
Primary
Concomitant
Urine Output Increased Other Serious 6/13/2006 89 Male 183 lb 12/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Tachycardia Other Serious 44 Female 12/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 12/28/2006 Physician United States
Primary
Concomitant
Tachycardia Other Serious 44 Female 12/29/2006 United States
Primary
Concomitant
Interacting
Tachycardia Hospitalization 44 Female 12/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 44 Female 12/23/2006 Physician United States
Primary
Secondary
Concomitant
Cardiogenic Shock Death 3/11/2006 91 Male 154 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Hospitalization 9/14/2006 62 Male 217 lb 9/27/2006 United States
Primary
Concomitant
Drug Interaction Other Serious 8/31/2006 74 Male 1/11/2007 Sweden
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/1/2006 79 Male 1/18/2007 Physician China
Primary
Concomitant
Therapeutic Response Decreased 2/27/2006 Male 127 lb 1/24/2007 Physician United States
Primary
Secondary
Concomitant
Photophobia Other Serious 1/1/2006 69 Male 165 lb 11/14/2006 United States
Primary
Concomitant
Metrorrhagia Other Serious 12/20/2006 92 Female 1/18/2007 Poland
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 12/20/2006 72 Male 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chest Pain Other Serious 12/22/2006 1/30/2007 Consumer United Kingdom
Primary
Concomitant
Urticaria Required Intervention 10/20/2006 1 Female 26 lb 1/25/2007 Other Health Professional United States
Primary
Concomitant
Subdural Haemorrhage Hospitalization 1/19/2007 66 Male 1/26/2007 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/6/2006 77 Male 123 lb 12/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 10/31/2006 78 Male 2/8/2007 Pharmacist Spain
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 12/15/2006 69 Male 2/7/2007 Pharmacist United States
Primary
Concomitant
Urticaria Required Intervention 1/5/2007 2 Female 26 lb 2/8/2007 Physician United States
Primary
Concomitant
Hyperkalaemia Hospitalization 4/30/2005 56 Male 2/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/1/2006 79 Male 3/6/2007 Physician China
Primary
Concomitant
Protein Urine Required Intervention 70 Male 2/23/2006 United States
Primary
Concomitant
Septic Shock Death 9/30/2006 60 Female 3/27/2007 Physician Spain
Primary
Secondary
Concomitant
Protein Urine Required Intervention 7/21/2005 70 Male 189 lb 6/2/2006 United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 52 Female 3/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Melaena Hospitalization 1/22/2007 61 Male 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Lung Disorder 6/1/2006 19 Male 93 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Cardiac Failure Other Serious 72 Male 4/6/2007 Pharmacist Ireland
Primary
Concomitant
Loss Of Consciousness Other Serious 3/3/2007 Male 134 lb 4/9/2007 Physician Czech Republic
Primary
Concomitant
Neuroendocrine Carcinoma Of The Skin Life Threatening 7/20/2006 80 Female 4/2/2007 Brazil
Primary
Concomitant
Atrioventricular Block Complete Hospitalization 4/3/2007 Male 4/14/2007 Other Health Professional Australia
Primary
Concomitant
Neuroendocrine Carcinoma Of The Skin Life Threatening 7/20/2006 80 Female 4/6/2007 Brazil
Primary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 4/18/2007 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 11/23/2006 92 Male 4/20/2007 Consumer Australia
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/31/2006 79 Male 211 lb 4/20/2007 Other Health Professional Ireland
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 4/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Neuroendocrine Carcinoma Of The Skin Life Threatening 7/20/2006 80 Female 4/23/2007 Brazil
Primary
Concomitant
Palpitations Other Serious 8/1/2006 38 Female 5/10/2007 Physician United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 5/11/2007 Other Health Professional France
Primary
Secondary
Concomitant
Atrioventricular Block Complete Hospitalization 4/3/2007 Male 5/16/2007 Other Health Professional Australia
Primary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 5/17/2007 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/1/2006 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/31/2006 79 Male 211 lb 5/25/2007 Consumer United Kingdom
Primary
Concomitant
Visual Disturbance Hospitalization 66 Male 5/24/2007 United States
Primary
Concomitant
Subarachnoid Haemorrhage Life Threatening 5/30/2007 73 Male 6/13/2007 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 72 Female 115 lb 6/22/2007
Primary
Secondary
Photopsia Hospitalization 72 Female 6/25/2007 Japan
Primary
Secondary
Concomitant
Photopsia Hospitalization 72 Female 6/28/2007 Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/31/2006 72 Male 211 lb 6/29/2007 Ireland
Primary
Concomitant
Sudden Death Death 10/10/2003 61 Female 7/16/2007 Korea, Republic Of
Primary
Concomitant
Visual Field Defect Hospitalization 72 Female 115 lb 7/25/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 3/17/2007 68 Female 185 lb 7/25/2007 United States
Primary
Concomitant
Loss Of Consciousness Disability 4/14/2007 59 Male 243 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/11/2004 52 Male 7/31/2007 Canada
Primary
Concomitant

Drug Data