Carvedilol combined with Coumadin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myalgia Hospitalization 12/1/2001 Male 174 lb 1/6/2006 United States
Primary
Concomitant
Vertigo Life Threatening 8/28/2005 Male 223 lb 1/13/2006 United States
Primary
Secondary
Concomitant
Interacting
Hyperkalaemia Required Intervention 1/10/2006 84 Male 144 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Dizziness Hospitalization 11/2/2005 Male 166 lb 12/2/2005 Pharmacist United States
Primary
Secondary
Concomitant
Procedural Hypotension Required Intervention 11/8/2005 90 Male 198 lb 1/31/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Procedural Hypotension Other Serious 11/8/2005 90 Male 198 lb 2/17/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Catheter Site Haemorrhage Hospitalization 10/11/2004 65 Male 217 lb 12/21/2005 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 12/1/2003 75 Male 140 lb 12/21/2005 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 8/17/2005 72 Male 8/8/2006 Consumer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Required Intervention 5/3/2006 67 Female 8/16/2006 Physician United States
Primary
Concomitant
Death Death 11/1/2005 71 Male 150 lb 7/12/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Required Intervention 8/13/2006 64 Male 242 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 65 Female 146 lb 12/12/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2006 65 Female 146 lb 12/12/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2006 65 Female 146 lb 12/20/2006 Physician United States
Primary
Secondary
Concomitant
Hypoxia Hospitalization 7/23/2006 81 9/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Hospitalization 9/14/2006 62 Male 217 lb 9/27/2006 United States
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 65 Female 146 lb 1/18/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased 2/27/2006 Male 127 lb 1/24/2007 Physician United States
Primary
Secondary
Concomitant
Hypotension 11/8/2005 90 Male 196 lb 1/31/2007 Canada
Primary
Secondary
Concomitant
Hypotension 11/8/2005 90 Male 196 lb 1/31/2007 Canada
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 12/18/2006 74 Male 2/7/2007 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/15/2006 69 Male 2/7/2007 Pharmacist United States
Primary
Concomitant
Myalgia Hospitalization 1/5/2007 55 150 lb 2/9/2007 Physician France
Primary
Concomitant
Interacting
Headache Other Serious 9/1/2006 Male 175 lb 12/6/2006 Pharmacist United States
Primary
Concomitant
Partial Seizures Hospitalization 3/13/2007 81 Male 3/27/2007 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/1/2006 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 1/1/2006 68 Female 9/13/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 9/11/2007 66 Male 206 lb 9/27/2007 Pharmacist United States
Primary
Concomitant
Loss Of Libido 9/1/2003 73 Male 11/13/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 57 Male 11/13/2007 Consumer United States
Primary
Concomitant
Collapse Of Lung Hospitalization 74 Female 5/21/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 232 lb 5/28/2008 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2008 88 Male 5/23/2008 United States
Primary
Concomitant
Palpitations Required Intervention 6/2/2008 57 Female 110 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Required Intervention 6/2/2008 57 Female 110 lb 6/23/2008 Physician United States
Primary
Secondary
Concomitant
Melaena Other Serious 4/10/2008 88 Male 7/3/2008 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 232 lb 7/17/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 6/1/2008 81 Female 139 lb 9/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Life Threatening 9/7/2008 72 Male 9/15/2008 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Somnolence Life Threatening 9/7/2008 72 Male 9/23/2008 Physician Italy
Primary
Secondary
Concomitant
Somnolence Life Threatening 9/1/2008 72 Male 9/25/2008 Physician Italy
Primary
Secondary
Concomitant
Somnolence Life Threatening 9/1/2008 72 Male 9/26/2008 Physician Italy
Primary
Secondary
Concomitant
Pruritus 9/28/2007 69 Male 11/13/2008 Consumer United States
Primary
Concomitant
Myalgia 1/1/2008 60 Male 11/13/2008 Consumer United States
Primary
Concomitant
Fatigue 74 Female 11/13/2008 Consumer United States
Primary
Concomitant
Wound Haemorrhage Life Threatening 9/11/2007 67 Male 11/20/2008 United States
Primary
Concomitant
Hypotension 11/3/2008 68 Male 12/9/2008 Consumer
Primary
Concomitant
Hip Fracture Other Serious 11/10/2008 Female 12/29/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 74 Male 12/29/2008 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 74 Male 12/29/2008 Lawyer United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 10/1/2008 Male 125 lb 1/13/2009 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 1/26/2009 Male 131 lb 2/10/2009 Consumer United States
Primary
Concomitant
Vertigo Other Serious 1/26/2009 Male 131 lb 2/13/2009 Consumer United States
Primary
Concomitant
Palpitations Other Serious 11/23/2007 79 Female 2/16/2009 Consumer United States
Primary
Concomitant
Palpitations Other Serious 11/23/2008 79 Female 2/19/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/26/2009 Male 131 lb 2/24/2009 Consumer United States
Primary
Concomitant
Urinary Bladder Haemorrhage Male 2/24/2009 United States
Primary
Concomitant
Hip Fracture Other Serious 11/10/2008 Female 171 lb 2/27/2009 United States
Primary
Concomitant
Hyponatraemia Hospitalization 2/4/2009 83 Male 3/4/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 2/4/2009 83 Male 3/11/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Blood Glucose Increased 10/14/2008 75 Male 234 lb 2/3/2009 Physician United States
Primary
Concomitant
Dyspnoea 3/21/2009 Male 4/7/2009 Consumer
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/20/2009 Female 5/6/2009 Consumer
Primary
Concomitant
Paraesthesia Other Serious 57 Female 116 lb 5/7/2009 Lawyer United States
Primary
Concomitant
Renal Failure Hospitalization 4/1/2009 29 Male 5/13/2009 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea 3/21/2009 Male 5/20/2009 Consumer
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 6/2/2008 57 Female 110 lb 5/18/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Death 64 Male 179 lb 6/5/2009 Lawyer United States
Primary
Concomitant
Social Problem Death 79 Female 7/1/2009 Lawyer United States
Primary
Concomitant
Palpitations Hospitalization 83 Female 170 lb 7/2/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/22/2009 75 Male 7/7/2009 United States
Primary
Concomitant
Unevaluable Event Death 65 Female 155 lb 7/10/2009 United States
Primary
Concomitant
Vomiting Death 35 Male 7/15/2009 United States
Primary
Concomitant
Sensation Of Pressure Other Serious 57 Female 136 lb 7/15/2009 Lawyer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/9/2007 Male 174 lb 7/21/2009 Physician United States
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 4/28/2008 84 Male 7/22/2009 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 77 Male 7/22/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 10/22/2008 82 Female 161 lb 7/22/2009 Consumer United States
Primary
Concomitant
Pruritus 89 Male 139 lb 7/22/2009 Consumer United States
Primary
Concomitant
Prothrombin Time Ratio Decreased 3/1/2009 71 Male 161 lb 7/22/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Death 34 Male 95 lb 7/19/2009 United States
Primary
Concomitant
Sensation Of Pressure 11/1/2008 Male 7/23/2009 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 6/22/2009 Female 7/24/2009 Consumer Italy
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 4/28/2008 84 Male 7/22/2009 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 77 Male 7/22/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 10/22/2008 82 Female 161 lb 7/22/2009 Consumer United States
Primary
Concomitant
Pruritus 89 Male 139 lb 7/22/2009 Consumer United States
Primary
Concomitant
Prothrombin Time Ratio Decreased 3/1/2009 71 Male 161 lb 7/22/2009 Physician United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 7/6/2009 77 Female 8/6/2009 Physician Italy
Primary
Concomitant
Vomiting Death 34 Male 95 lb 7/22/2009 Lawyer United States
Primary
Concomitant
Skin Tightness Other Serious 6/10/2004 50 Male 198 lb 8/7/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 80 Male 7/31/2009 United States
Primary
Concomitant
Vomiting Death 7/30/1989 16 Male 95 lb 8/5/2009 Lawyer United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/5/2009 Lawyer United States
Primary
Concomitant
Pyrexia Hospitalization 4/25/2009 75 Female 177 lb 8/12/2009 Physician United States
Primary
Secondary
Concomitant
Sensation Of Pressure Other Serious 57 Female 136 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 73 Male 229 lb 8/4/2009 United States
Primary
Concomitant
Tonic Clonic Movements Other Serious 7/31/2009 Male 8/12/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 64 Male 179 lb 8/13/2009 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/13/2009 Lawyer United States
Primary
Concomitant
Flushing Male 8/22/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 79 Male 8/18/2009 United States
Primary
Concomitant
Pruritus 6/18/2009 Male 200 lb 8/23/2009 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 51 Male 8/20/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 70 Male 8/20/2009 United States
Primary
Concomitant
Unevaluable Event Death 62 Male 8/25/2009 Lawyer United States
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 7/6/2009 78 Female 9/1/2009 Physician Italy
Primary
Concomitant
Weight Decreased Hospitalization 80 Male 8/26/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 65 Female 155 lb 8/24/2009 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/31/2009 United States
Primary
Concomitant
Unevaluable Event Death Male 8/31/2009 United States
Primary
Concomitant
Vomiting Death 7/30/1989 16 Male 95 lb 9/1/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 74 Male 8/31/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 Male 200 lb 9/9/2009 Consumer United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 9/8/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/14/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 64 Female 155 lb 9/17/2009 United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 3/1/2008 61 Male 123 lb 9/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Death 64 Male 179 lb 9/23/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 80 Male 9/25/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 9/24/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death Male 9/22/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 68 Male 229 lb 9/24/2009 United States
Primary
Concomitant
Pain Death 62 Male 9/22/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/9/2004 51 Male 207 lb 10/8/2009 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 Male 200 lb 10/6/2009 Consumer United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration 1/1/2007 Female 119 lb 10/13/2009 Consumer United States
Primary
Concomitant
Visual Impairment 8/1/2008 85 Female 10/16/2009 Consumer United States
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased 6/1/2009 Female 10/16/2009 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/12/2009 United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 9/8/2009 Male 10/19/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 10/9/2009 United States
Primary
Concomitant
Wrist Fracture Death 1/31/2006 79 Male 162 lb 10/9/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 80 Male 10/18/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Male 10/22/2009 United States
Primary
Concomitant
Tremor Other Serious 1/1/2009 79 Female 11/2/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/26/2009 United States
Primary
Concomitant
Wrist Fracture Death 1/31/2006 79 Male 162 lb 10/26/2009 United States
Primary
Concomitant
Vertigo Hospitalization 79 Male 10/26/2009 Lawyer United States
Primary
Concomitant
Pruritus Other Serious 1/1/2006 Male 245 lb 11/6/2009 Consumer United States
Primary
Concomitant
Oesophageal Haemorrhage Other Serious 8/1/2009 Male 11/9/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 72 Male 11/9/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 69 Female 11/4/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 11/9/2009 United States
Primary
Concomitant
Fatigue 1/1/2008 Female 11/13/2009 Consumer United States
Primary
Concomitant
Fatigue 72 Male 11/13/2009 Consumer United States
Primary
Concomitant

Drug Data