Carfilzomib combined with Dexamethasone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sick Sinus Syndrome Life Threatening 7/9/2009 77 Female 5/5/2010 United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 8/3/2010 62 Male 220 lb 8/26/2010 Other Health Professional United States
Primary
Concomitant
Intestinal Dilatation Hospitalization 7/27/2010 80 Female 92 lb 9/10/2010 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/27/2010 80 Female 92 lb 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 1/4/2010 68 Female 100 lb 1/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 1/4/2011 69 Female 100 lb 1/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Palpitations Hospitalization 1/4/2011 69 Female 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Life Threatening 12/21/2010 70 Male 174 lb 2/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Methaemoglobinaemia Hospitalization 1/4/2011 69 Female 100 lb 2/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Myeloma Life Threatening 12/21/2010 70 Male 174 lb 2/22/2011 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Other Serious 12/21/2010 70 Male 174 lb 2/22/2011 Physician United States
Primary
Secondary
Concomitant
Hypocalcaemia Life Threatening 2/14/2011 61 Male 174 lb 5/9/2011 Other Health Professional Romania
Primary
Secondary
Concomitant
Electrolyte Imbalance Life Threatening 2/14/2011 61 Male 174 lb 5/12/2011 Other Health Professional Romania
Primary
Secondary
Concomitant
Electrolyte Imbalance Hospitalization 2/14/2011 61 Male 174 lb 6/1/2011 Other Health Professional Romania
Primary
Secondary
Concomitant
Colonic Stenosis Death 7/27/2010 80 Female 92 lb 6/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Breast Cancer Metastatic Other Serious 1/28/2010 73 Female 136 lb 6/27/2011 Physician United States
Primary
Secondary
Concomitant
Hypoalbuminaemia Life Threatening 2/14/2011 61 Male 174 lb 6/30/2011 Other Health Professional Romania
Primary
Secondary
Concomitant
Blood Sodium Decreased Other Serious 2/14/2011 61 Male 174 lb 7/8/2011 Other Health Professional Romania
Primary
Secondary
Concomitant
Hypocalcaemia Life Threatening 2/14/2011 61 Male 174 lb 7/12/2011 Other Health Professional Romania
Primary
Secondary
Concomitant
Peripheral Motor Neuropathy Other Serious 7/28/2011 United States
Primary
Secondary
Breast Cancer Metastatic Other Serious 1/28/2010 73 Female 136 lb 8/4/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/7/2011 67 Male 223 lb 9/21/2011 Physician Sweden
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/7/2011 67 Male 223 lb 9/28/2011 Physician Sweden
Primary
Secondary
Concomitant
Sick Sinus Syndrome Life Threatening 7/9/2009 77 Female 10/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2007 53 Male 12/1/2011 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Disability 10/14/2011 71 Female 132 lb 12/7/2011 Other Health Professional Hungary
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 5/17/2011 64 Female 165 lb 12/8/2011 Physician Spain
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Other Serious 11/18/2011 65 Female 224 lb 12/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/16/2012 78 Male 183 lb 2/6/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/16/2012 78 Male 183 lb 2/16/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Colorectal Cancer Hospitalization 1/4/2012 50 Male 179 lb 2/29/2012 Other Health Professional Bulgaria
Primary
Secondary
Altered State Of Consciousness Hospitalization 2/14/2012 72 Female 115 lb 3/1/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Vasculitis Hospitalization 2/21/2012 70 Male 179 lb 3/6/2012 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 2/14/2012 73 Female 115 lb 3/13/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Colorectal Cancer Other Serious 1/5/2012 50 Male 179 lb 3/14/2012 Other Health Professional Bulgaria
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 3/13/2012 77 Male 172 lb 3/21/2012 Other Health Professional Sweden
Primary
Secondary
Concomitant
Asthenia Hospitalization 8/11/2011 68 Female 165 lb 3/28/2012 Other Health Professional Austria
Primary
Secondary
Concomitant
Platelet Disorder Hospitalization 2/21/2012 70 Male 179 lb 3/30/2012 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 4/4/2012 Netherlands
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/23/2012 79 Male 179 lb 4/10/2012 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 3/13/2012 77 Male 172 lb 4/24/2012 Other Health Professional Sweden
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 1/16/2012 79 Male 183 lb 5/1/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 4/23/2012 79 Male 220 lb 5/3/2012 Other Health Professional Spain
Primary
Secondary
Concomitant
Platelet Disorder Hospitalization 2/21/2012 70 Male 179 lb 5/4/2012 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 1/16/2012 79 Male 183 lb 5/10/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 4/23/2012 79 Male 220 lb 5/14/2012 Other Health Professional Spain
Primary
Secondary
Concomitant
Hepatitis C Hospitalization 4/3/2012 62 Male 134 lb 5/22/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 2/21/2012 70 Male 179 lb 6/4/2012 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Prostate Cancer Metastatic Other Serious 5/22/2012 66 Male 265 lb 6/4/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Embolism Other Serious 6/6/2012 United States
Primary
Secondary
Concomitant
Death Other Serious 6/8/2012 Other Health Professional United States
Primary
Secondary
Anxiety Other Serious 6/11/2012 Other Health Professional United States
Primary
Secondary
Platelet Disorder Hospitalization 2/21/2012 70 Male 179 lb 6/14/2012 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 6/15/2012 Physician United States
Primary
Secondary
Neutropenic Colitis Hospitalization 11/29/2011 60 237 lb 6/22/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 6/23/2012 68 Female 141 lb 6/26/2012 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/11/2011 68 Female 165 lb 7/18/2012 Other Health Professional Austria
Primary
Secondary
Concomitant
Colitis Hospitalization 6/25/2012 52 Female 145 lb 7/18/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Hospitalization 6/27/2012 52 Female 145 lb 7/20/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis C Hospitalization 4/3/2012 62 Male 134 lb 7/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Brain Mass Hospitalization 7/13/2012 68 Male 176 lb 7/25/2012 Other Health Professional France
Primary
Secondary
Concomitant
Myocardial Infarction Death 7/31/2012 74 Male 182 lb 8/8/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Hospitalization 6/27/2012 52 Female 145 lb 8/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pathological Fracture Other Serious 1/5/2012 50 Male 179 lb 8/14/2012 Other Health Professional Bulgaria
Primary
Secondary
Concomitant
Myocardial Infarction Death 7/31/2012 74 Male 182 lb 8/15/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Hospitalization 6/27/2012 52 Female 145 lb 8/15/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Plasmacytoma Hospitalization 7/13/2012 68 Male 176 lb 8/17/2012 Other Health Professional France
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 2/14/2011 62 Male 174 lb 6/21/2013 Other Health Professional Ro
Primary
Secondary
Concomitant
Vision Blurred Death NotSpecified 9/26/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 10/14/2011 72 Female 132 lb 10/24/2013 Other Health Professional Hu
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Other Serious 11/18/2011 65 Female 224 lb 12/20/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/25/2011 62 Male 181 lb 9/4/2012 Other Health Professional It
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/16/2012 79 Male 183 lb 5/22/2013 Physician Cz
Primary
Secondary
Concomitant
Pathological Fracture Hospitalization 1/4/2012 51 Male 179 lb 9/4/2012 Other Health Professional Bg
Primary
Secondary
Concomitant
Chronic Hepatitis C Hospitalization 4/3/2012 63 Male 134 lb 9/5/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombocytopenia Death NotSpecified 11/20/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Colitis Hospitalization 6/25/2012 53 Female 145 lb 6/12/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Cardiac Arrest Death 7/31/2012 75 Male 182 lb 10/19/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 8/31/2012 59 Female 163 lb 9/18/2012 Other Health Professional Hu
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 9/19/2012 Other Health Professional Us
Primary
Secondary
Dysphagia Other Serious 9/8/2012 66 Female 149 lb 9/28/2012 Physician Us
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/8/2012 73 Male 240 lb 10/29/2012 Physician Us
Primary
Concomitant
Pleural Mesothelioma Malignant Life Threatening 7/11/2012 75 Male 132 lb 4/25/2013 Physician Pl
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/7/2012 62 Male 181 lb 10/18/2012 Physician It
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/7/2012 62 Male 181 lb 8/2/2013 Physician It
Primary
Secondary
Concomitant
Plasma Cell Myeloma Death 10/7/2012 59 Female 11/28/2012 Physician Us
Primary
Concomitant
Hypomagnesaemia Hospitalization 10/8/2012 63 Male 157 lb 11/28/2012 Physician Es
Primary
Secondary
Concomitant
Paraparesis Other Serious 9/13/2012 65 Female 150 lb 5/22/2013 Other Health Professional Bg
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 10/14/2012 70 Male 7/31/2013 Physician Be
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 10/23/2012 69 Male 147 lb 11/8/2012 Other Health Professional Es
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/24/2012 42 Male 193 lb 12/17/2012 Physician Us
Primary
Secondary
Pleural Effusion Hospitalization 10/25/2012 66 Female 128 lb 11/6/2012 Physician Us
Primary
Secondary
Pulmonary Embolism Life Threatening 10/19/2012 74 Female 128 lb 1/15/2013 Physician Hu
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 10/12/2012 69 NotSpecified 11/29/2012 Physician It
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 10/23/2012 68 Male 147 lb 11/6/2012 Physician Es
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 11/3/2012 66 Male 216 lb 12/21/2012 Pl
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/24/2012 42 Male 193 lb 11/14/2012 Physician Us
Primary
Secondary
Influenza Like Illness Hospitalization 10/12/2012 49 191 lb 11/14/2012 Physician Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/29/2012 57 Male 163 lb 12/6/2012 Physician Us
Primary
Secondary
Thrombocytopenia Hospitalization 11/23/2012 57 Male 12/12/2012 Pharmacist Us
Primary
Concomitant
Unresponsive To Stimuli Death 11/12/2012 73 Male 276 lb 12/6/2012 Us
Primary
Secondary
Thrombosis Death 12/21/2012 Country Not Specified
Primary
Concomitant
Thrombosis Other Serious NotSpecified 12/30/2013 Country Not Specified
Primary
Concomitant
Renal Failure Acute Death 12/23/2012 77 Male 208 lb 4/29/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 2/11/2013 Male 2/22/2013 Physician Us
Primary
Secondary
Concomitant
Haemophilus Infection Hospitalization 2/10/2013 55 Female 2/12/2013 Physician Us
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 10/4/2012 66 Male 216 lb 11/28/2013 Other Health Professional Pl
Primary
Secondary
Concomitant
Infection Hospitalization 2/25/2013 48 Male 196 lb 3/5/2013 Other Health Professional Us
Primary
Secondary
Syncope Hospitalization 12/29/2012 71 Male 211 lb 3/7/2013 Physician Us
Primary
Secondary
Concomitant
Malaise Hospitalization 1/15/2013 65 Female 172 lb 2/21/2013 Physician Fr
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious NotSpecified 3/22/2013 Physician Us
Primary
Secondary
Tachycardia Hospitalization 2/20/2013 66 Male 228 lb 3/19/2013 Physician Us
Primary
Concomitant
Peritonitis Life Threatening 3/21/2013 58 Male 159 lb 6/4/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Renal Failure Other Serious NotSpecified 4/15/2013 Physician It
Primary
Secondary
Pneumonia Other Serious NotSpecified 4/15/2013 Physician It
Primary
Secondary
Atrial Fibrillation Other Serious NotSpecified 4/15/2013 Physician It
Primary
Secondary
Plasma Cell Myeloma Life Threatening 11/15/2012 74 Male 177 lb 5/29/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Pneumonia Other Serious NotSpecified 4/16/2013 Physician It
Primary
Secondary
Squamous Cell Carcinoma Of Skin Other Serious 2/27/2013 61 Male 7/10/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 4/26/2012 70 Female 4/22/2013 Physician Us
Primary
Concomitant
Adenocarcinoma Of Colon Hospitalization 3/28/2013 60 Female 194 lb 9/24/2013 Physician De
Primary
Secondary
Concomitant
Hypoxia Hospitalization 4/10/2013 65 Male 205 lb 7/23/2013 Physician Us
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/24/2012 61 Male 6/25/2012 Registered Nurse Us
Primary
Secondary
Dysphagia Death 5/1/2013 78 Female 139 lb 5/29/2013 Physician Us
Primary
Concomitant
Rotator Cuff Syndrome Disability 5/25/2012 65 Female 172 lb 10/21/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Social Problem Other Serious 4/19/2013 70 Female 7/2/2013 Physician Au
Primary
Secondary
Concomitant
Plasma Cell Myeloma Death 5/5/2013 54 Male 160 lb 7/12/2013 Physician Us
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 10/2012 76 Male 7/9/2013 Physician Us
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/2/2013 66 Female 125 lb 5/31/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Plasma Cell Myeloma Other Serious 2013 Male 157 lb 10/1/2013 Physician Us
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/29/2013 81 Male 181 lb 8/13/2013 Physician Ca
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/12/2013 43 Male 183 lb 6/28/2013 Other Health Professional Us
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 5/14/2013 73 Male 147 lb 8/28/2013 Physician Us
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 6/27/2013 64 Male 7/16/2013 Physician Ca
Primary
Secondary
Hypertension Hospitalization 7/6/2013 80 Male 146 lb 7/19/2013 Physician Us
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 7/5/2013 86 Male 137 lb 8/14/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 59 Female 7/30/2013 Other Health Professional Us
Primary
Concomitant
Pneumonia Hospitalization 2/14/2013 58 Male 198 lb 8/1/2013 Other Health Professional Us
Primary
Secondary
Plasma Cell Myeloma Other Serious 9/2012 65 Female 166 lb 8/2/2013 Physician Us
Primary
Secondary
Concomitant
Plasma Cell Myeloma Death 6/3/2013 59 Male 244 lb 8/20/2013 Other Health Professional Us
Primary
Secondary
Melanocytic Naevus Other Serious 3/27/2009 62 Female 11/1/2013 Other Health Professional Us
Primary
Concomitant
Plasma Cell Myeloma Other Serious 2013 Male 8/30/2013 Physician Us
Primary
Secondary
Concomitant
Plasma Cell Myeloma Other Serious 8/9/2013 63 Male 152 lb 10/21/2013 Physician Nl
Primary
Concomitant
Cardiac Disorder Hospitalization 7/10/2012 65 Male 208 lb 9/4/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Chest Pain Life Threatening 8/29/2013 54 Male 180 lb 9/3/2013 Physician Us
Primary
Concomitant
Neutropenia Other Serious NotSpecified 9/12/2013 Other Health Professional Us
Primary
Secondary
Pancreatitis Hospitalization 9/2/2013 86 Female 10/22/2013 Physician Fr
Primary
Secondary
Concomitant
Pulmonary Hypertension Death 7/25/2013 57 Female 9/12/2013 Physician Fr
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Test Positive Hospitalization 9/6/2013 51 Male 10/7/2013 Physician Nz
Primary
Secondary
Concomitant
Vasculitis Hospitalization 2/21/2012 70 Male 179 lb 8/14/2013 Other Health Professional Ru
Primary
Secondary
Concomitant

Drug Data