Carboplatin combined with Thiotepa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Disability 21 Female 3/29/2006 Physician Netherlands
Primary
Secondary
Encephalopathy Other Serious 21 Female 4/6/2006 Other Health Professional Netherlands
Primary
Secondary
Hypertonia Required Intervention 21 Female 3/29/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 10 Male 6/9/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Neoplasm Recurrence Hospitalization 1/1/2006 21 Female 6/7/2006 Other Health Professional Netherlands
Primary
Secondary
Respiratory Disorder Death 2/26/2004 6 Male 6/16/2006 Consumer Japan
Primary
Secondary
Vomiting Hospitalization 10 Male 6/12/2006 Other Health Professional Germany
Primary
Secondary
Pneumatosis Intestinalis Hospitalization 10 Male 6/15/2006 Germany
Primary
Secondary
Concomitant
Bone Sarcoma Death 2/1/2004 5 Male 6/29/2006 Consumer United States
Primary
Secondary
Bone Sarcoma Death 2/1/2004 5 Male 7/6/2006 Consumer United States
Primary
Secondary
Stem Cell Transplant Death 21 Female 7/6/2006 Physician United States
Primary
Secondary
Miosis Death 4/17/2006 3 Female 31 lb 7/25/2006 Consumer France
Primary
Secondary
Gastrointestinal Fungal Infection Required Intervention 5/1/2005 10 Male 8/14/2006 Physician Germany
Primary
Secondary
Myelitis Transverse Other Serious 5 Male 9/6/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 18 Female 9/6/2006 United States
Primary
Secondary
Concomitant
Paraplegia Required Intervention 5 Male 9/29/2006 Physician United States
Primary
Secondary
Walking Aid User Required Intervention 18 Female 9/29/2006 Physician United States
Primary
Secondary
Concomitant
Myelitis Other Serious 18 Female 10/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 18 Female 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 5 Male 10/25/2006 Physician United States
Primary
Secondary
Myelitis Transverse Other Serious 5 Male 11/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myelitis Other Serious 18 Female 3/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myelitis Other Serious 5 Male 3/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 4/5/2007 Other Health Professional United States
Primary
Secondary
Venous Occlusion Hospitalization 5/21/2007 Male 26 lb 5/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myelitis Transverse Other Serious 18 Female 5/28/2007 Physician United States
Primary
Secondary
Rash Other Serious 17 Male 8/14/2007 Consumer Czech Republic
Primary
Secondary
Tooth Abscess Other Serious 1/1/2004 53 Female 9/29/2007 France
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 11 Male 3/1/2008 Consumer Hong Kong
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 5 Female 3/1/2008 Consumer Hong Kong
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Female 3/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious Female 3/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious Female 3/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Other Serious Female 3/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Interaction Other Serious 52 Female 5/12/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 12 Female 11/27/2008 Physician United States
Primary
Secondary
Stem Cell Transplant Other Serious 12 Female 12/2/2008 Physician United States
Primary
Secondary
Neuropathy Peripheral Other Serious 12 Female 12/29/2008 Other Health Professional United States
Primary
Secondary
Stem Cell Transplant Other Serious 12 Female 12/23/2008 Other Health Professional United States
Primary
Secondary
Spinal Disorder Other Serious 12 Female 1/6/2009 Other Health Professional United States
Primary
Secondary
Stem Cell Transplant Other Serious 12 Female 1/6/2009 Physician United States
Primary
Secondary
Spinal Disorder Other Serious 12 Female 1/9/2009 United States
Primary
Secondary
Malignant Neoplasm Progression Other Serious 12 Female 1/13/2009 Physician United States
Primary
Secondary
Neuropathy Peripheral Other Serious 12 Female 1/22/2009 United States
Primary
Secondary
Neuropathy Peripheral Other Serious 12 Female 1/28/2009 United States
Primary
Secondary
Neurological Examination Abnormal Other Serious 39 Female 2/17/2009 Italy
Primary
Secondary
Nuclear Magnetic Resonance Imaging Brain Abnormal Other Serious 39 Female 2/23/2009 Physician Italy
Primary
Secondary
Vomiting Other Serious 52 Female 2/26/2009
Primary
Secondary
Drug Interaction Other Serious 52 Female 3/2/2009 Netherlands
Primary
Concomitant
Interacting
Vomiting Other Serious 52 Female 3/5/2009 Netherlands
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 4/10/2009 Female 37 lb 4/14/2009 United States
Primary
Secondary
Visual Impairment Other Serious 31 Female 5/5/2009 Other Health Professional Canada
Primary
Secondary
Visual Impairment Other Serious 31 Female 5/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 52 Female 5/20/2009 Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious Female 5/22/2009 Physician Netherlands
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 5/28/2009 Male 27 lb 6/1/2009 United States
Primary
Secondary
Thrombotic Microangiopathy Hospitalization 5/28/2009 Male 27 lb 6/5/2009 United States
Primary
Secondary
Thrombotic Microangiopathy Hospitalization 5/28/2009 Male 27 lb 6/15/2009 United States
Primary
Secondary
Hypokalaemia Other Serious 6/19/2009 Male 36 lb 6/24/2009 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 0 Female 8/27/2009 Other Health Professional Italy
Primary
Secondary
Respiratory Distress Life Threatening 9/10/2009 Male 25 lb 9/14/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious Unknown 10/2/2009 Korea, Republic Of
Primary
Secondary
Thrombotic Microangiopathy Hospitalization 5/28/2009 Male 27 lb 9/29/2009 United States
Primary
Secondary
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 12/4/2009 United States
Primary
Secondary
Parotitis Other Serious 8 Female 12/15/2009 Physician Japan
Primary
Secondary
Capillary Leak Syndrome Death Unknown 12/14/2009 Italy
Primary
Secondary
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 12/23/2009 United States
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 11/12/2009 Female 15 lb 12/30/2009 United States
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/21/2009 Male 48 lb 2/24/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Required Intervention 4 Male 3/10/2010 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 7 Male 3/10/2010 Physician United States
Primary
Secondary
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Stem Cell Transplant Death 16 3/23/2010 United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6 Male 4/13/2010 Japan
Primary
Concomitant
Pyrexia Other Serious 9 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 13 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 1 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Death 17 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Death 7 5/4/2010 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 2 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Varicella Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5/19/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5/19/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Sepsis Death Unknown 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 6 Male 5/25/2010 Japan
Primary
Secondary
Urinary Tract Infection Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 7/1/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 8/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 8/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 0 Female 9/14/2010 Other Health Professional Japan
Primary
Concomitant
Ototoxicity Other Serious 30 Female 10/22/2010 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 12/2/2010 Lawyer United States
Primary
Concomitant
Multi-organ Failure Death 7/1/2007 1 Male 18 lb 1/27/2011 Physician United States
Primary
Concomitant
Irritability Hospitalization 3/1/2011 1 Male 24 lb 3/2/2011 Physician United States
Primary
Secondary
Haemoglobin Decreased Hospitalization 4/8/2011 1 Male 25 lb 4/15/2011 Physician United States
Primary
Secondary
Staphylococcal Infection Hospitalization 4/11/2011 3 Female 32 lb 4/14/2011 Physician United States
Primary
Secondary
Hypophagia Hospitalization 3/21/2011 2 Female 24 lb 4/20/2011 United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 11/18/2010 10 Male 4/27/2011 Consumer Spain
Primary
Secondary
Pallor Other Serious 1/1/2011 63 Female 212 lb 5/17/2011 Physician United States
Primary
Secondary
Concomitant
Dizziness Postural Hospitalization 1/1/2011 63 Female 196 lb 5/26/2011 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 5/25/2011 1 Female 24 lb 5/26/2011 United States
Primary
Secondary
Neoplasm Malignant Death 5 6/25/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Acute Graft Versus Host Disease Death 3 6/25/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Anaemia Hospitalization 6/22/2011 1 Female 23 lb 6/22/2011 United States
Primary
Secondary
Hypotension Hospitalization 6/22/2011 1 Female 23 lb 6/27/2011 United States
Primary
Secondary
Concomitant
Blister Other Serious 52 Female 8/5/2011 Other Health Professional Spain
Primary
Secondary
Metaplasia Other Serious 55 Female 8/5/2011 Other Health Professional Spain
Primary
Secondary
Dermatitis Other Serious 48 Male 8/8/2011 Physician Spain
Primary
Secondary
Skin Exfoliation Other Serious 52 Female 8/8/2011 Physician Spain
Primary
Secondary
Metaplasia Other Serious 55 Female 8/8/2011 Physician Spain
Primary
Secondary
Skin Exfoliation Other Serious 53 Male 8/8/2011 Physician Spain
Primary
Secondary
Dermatitis Other Serious 53 Male 8/9/2011 Other Health Professional Spain
Primary
Secondary
Oedema Other Serious 52 Female 8/9/2011 Other Health Professional Spain
Primary
Secondary
Metaplasia Other Serious 55 Female 8/9/2011 Other Health Professional Spain
Primary
Secondary
Metaplasia Other Serious 48 Male 8/9/2011 Other Health Professional Spain
Primary
Secondary
Oedema Other Serious 48 Male 8/10/2011 Other Health Professional Spain
Primary
Secondary
Skin Erosion Other Serious 53 Male 8/11/2011 Other Health Professional Spain
Primary
Secondary
Rash Other Serious 55 Female 8/10/2011 Spain
Primary
Secondary
Rash Other Serious 48 Male 8/10/2011 Spain
Primary
Secondary
Dermatitis Other Serious 52 Female 8/10/2011 Spain
Primary
Secondary
Obstruction Hospitalization 8/14/2011 Female 21 lb 8/16/2011 Physician United States
Primary
Secondary
Dermatitis Other Serious 53 Male 8/12/2011
Primary
Secondary
Dermatitis Other Serious 8/23/2011 Physician Spain
Primary
Secondary
Sputum Culture Positive Hospitalization 8/14/2011 Female 21 lb 8/30/2011 Physician United States
Primary
Secondary
Tachycardia Hospitalization 8/14/2011 Female 21 lb 9/22/2011 United States
Primary
Secondary
Breast Cancer In Situ Other Serious 21 Female 10/11/2011 Physician United States
Primary
Secondary
Recurrent Cancer Other Serious 21 Female 10/11/2011 Physician United States
Primary
Secondary

Drug Data