Carboplatin combined with Tarceva

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Failure Death 12/6/2005 57 Male 161 lb 12/30/2005 Physician United States
Primary
Concomitant
Dizziness 9/1/2005 80 Male 170 lb 12/7/2005 Consumer United States
Primary
Concomitant
Pain In Jaw Other Serious 6/1/2005 60 Male 2/7/2006 United States
Primary
Concomitant
Platelet Count Decreased Other Serious Female 1/19/2006 United States
Primary
Concomitant
Pneumonia Death 7/3/2005 59 Female 5/1/2006 Physician United States
Primary
Concomitant
Pain In Jaw Other Serious 6/1/2005 60 Male 5/17/2006 United States
Primary
Concomitant
Swelling Other Serious 6/1/2005 60 Male 5/24/2006 Physician United States
Primary
Concomitant
Sleep Disorder Disability 10/1/2005 63 Female 5/25/2006 Physician United States
Primary
Concomitant
Vertigo Hospitalization 73 Male 6/7/2006 Other Health Professional France
Primary
Secondary
Renal Failure Acute Hospitalization 4/10/2006 56 Female 6/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rheumatoid Factor Increased Disability 1/1/2006 63 Female 206 lb 6/20/2006 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/2/2006 73 Male 6/19/2006 France
Primary
Secondary
Concomitant
Sleep Disorder Disability 1/1/2006 63 Female 206 lb 7/20/2006 Physician United States
Primary
Concomitant
Rash Hospitalization 1/12/2006 62 Male 75 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Onychoclasis 11/1/2005 57 Female 5/24/2006 Consumer United States
Primary
Concomitant
Skin Disorder Hospitalization 12/1/2004 82 Male 5/24/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 2/1/2007 66 Male 188 lb 3/25/2007 Physician United States
Primary
Concomitant
Vascular Encephalopathy Other Serious 1/6/2007 Male 4/10/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Vascular Encephalopathy Other Serious 1/6/2007 61 Male 4/18/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/11/2006 53 Female 6/8/2007 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 12/11/2006 53 Female 6/8/2007 Physician United States
Primary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 7/26/2007 Physician United States
Primary
Concomitant
Pyrexia Other Serious 47 Male 7/17/2007 Physician Singapore
Primary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 8/2/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/30/2007 66 Female 168 lb 9/13/2007 Physician United States
Primary
Secondary
Rash Death 10/16/2007 58 Female 12/4/2007 Physician United Kingdom
Primary
Concomitant
Malignant Neoplasm Progression Death 7/4/2006 75 Female 3/5/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Stomatitis Hospitalization 3/7/2008 Male 3/26/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Stomatitis Hospitalization 3/7/2008 Male 3/27/2008 Pharmacist United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 4/8/2007 54 Female 96 lb 2/28/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 4/1/2008 73 Female 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Vasodilatation Life Threatening 3/11/2008 64 Male 5/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/1/2008 73 Female 148 lb 6/10/2008 Physician United States
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 10/1/2007 Female 8/5/2008 Physician Germany
Primary
Secondary
Concomitant
Oral Pain Hospitalization 8/20/2008 66 Male 186 lb 9/9/2008 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 1/1/2008 42 Male 9/5/2008 Pharmacist Canada
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 9/10/2007 51 Female 9/30/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/1/2008 Male 10/16/2008 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 36 Female 12/6/2008 Physician United Kingdom
Primary
Concomitant
No Therapeutic Response Other Serious 36 Female 12/12/2008 Other Health Professional United Kingdom
Primary
Secondary
No Therapeutic Response Other Serious 36 Female 12/11/2008 United Kingdom
Primary
Secondary
Sudden Death Death 60 Male 12/17/2008 Physician Iran (Islamic Republic Of)
Primary
Concomitant
Jaw Disorder Required Intervention 2/1/2007 Male 7/23/2008 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2007 Male 1/16/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 10/21/2008 35 Female 254 lb 2/13/2009 Physician United Kingdom
Primary
Concomitant
No Therapeutic Response Hospitalization 10/21/2008 35 Female 2/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Metastases To Lung Hospitalization 10/21/2008 35 Female 254 lb 2/13/2009 United Kingdom
Primary
Secondary
Concomitant
No Therapeutic Response Hospitalization 10/21/2008 36 Female 2/19/2009 United Kingdom
Primary
Secondary
Concomitant
Lung Cancer Metastatic Death 1/16/2009 Male 120 lb 3/18/2009 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/25/2009 65 Female 4/16/2009 Physician United Kingdom
Primary
Concomitant
Malignant Neoplasm Progression Death 7/4/2006 75 Female 5/6/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hallucination Hospitalization 4/27/2009 Female 144 lb 6/1/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Hallucination Hospitalization 4/27/2009 Female 144 lb 6/24/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 3/1/2009 68 Male 8/12/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Transaminases Increased Hospitalization 8/5/2009 74 Male 8/24/2009 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious 12/11/2006 Female 9/1/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/11/2006 Female 9/8/2009 Physician United States
Primary
Secondary
Concomitant
Treatment Failure Death 52 Male 8/31/2009 Greece
Primary
Secondary
Pleural Effusion Hospitalization 3/25/2009 65 Female 9/9/2009 Physician United Kingdom
Primary
Concomitant
Thrombosis Hospitalization 3/6/2009 65 Female 10/2/2009 Physician United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 10/21/2008 35 Female 254 lb 12/1/2009 Physician United Kingdom
Primary
Concomitant
Metastases To Central Nervous System Other Serious 1/1/2008 Female 12/22/2009 Physician Netherlands
Primary
Secondary
Non-small Cell Lung Cancer Other Serious 1/1/2008 Female 12/24/2009 Physician Netherlands
Primary
Secondary
Urinary Retention Other Serious 1/11/2007 Male 1/22/2010 Physician United States
Primary
Concomitant
Rash Other Serious 6/27/2008 41 Female 126 lb 2/5/2010 Physician Portugal
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 12/28/2009 Male 159 lb 2/25/2010 Physician Japan
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 12/28/2009 Male 159 lb 3/2/2010 Physician Japan
Primary
Secondary
Rash Other Serious 6/27/2008 41 Female 2/16/2010 Portugal
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/28/2009 Male 159 lb 3/3/2010 Physician Japan
Primary
Secondary
Vision Blurred Other Serious 2/11/2010 60 Male 2/23/2010 Consumer United States
Primary
Secondary
Urinary Retention Other Serious 1/11/2007 Male 3/15/2010 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 12/28/2009 46 Male 3/9/2010 Other Health Professional Japan
Primary
Secondary
Urinary Retention Other Serious 1/11/2007 Male 3/18/2010 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 12/28/2009 46 Male 3/12/2010 Physician Japan
Primary
Secondary
Thrombocytopenia Other Serious 12/28/2009 Male 159 lb 3/29/2010 Physician Japan
Primary
Secondary
Tumour Marker Increased Other Serious 1/1/2009 41 Female 3/23/2010 Consumer Portugal
Primary
Secondary
Concomitant
Radiotherapy Other Serious 1/1/2005 40 Male 4/6/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 6/22/2006 64 Male 4/7/2010 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 1/1/2009 41 Female 4/6/2010 Physician Portugal
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/28/2009 46 Male 159 lb 4/14/2010 Physician Japan
Primary
Secondary
Thrombocytopenia Other Serious 12/28/2009 46 Male 4/16/2010 Physician Japan
Primary
Secondary
Weight Decreased Other Serious 6/1/2006 64 Male 150 lb 5/14/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2006 64 Male 150 lb 6/15/2010 United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/1/2009 68 Female 7/2/2010 Other Health Professional Japan
Primary
Secondary
Therapeutic Response Decreased Other Serious 1/1/2010 57 Female 7/2/2010 Other Health Professional Japan
Primary
Secondary
Paraesthesia Other Serious 1/1/2009 68 Female 7/9/2010 Other Health Professional Japan
Primary
Secondary
Urinary Retention Other Serious 1/11/2007 56 Male 8/26/2010 Physician United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 9/7/2010 Physician Brazil
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious Female 9/14/2010 Physician Brazil
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/22/2006 64 Male 10/12/2010 Other Health Professional United States
Primary
Concomitant
Skin Reaction Hospitalization 7/27/2010 82 Male 10/7/2010 Physician United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 1/11/2007 56 Male 11/5/2010 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 40 Male 11/15/2010 Other Health Professional United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 1/1/2010 53 Female 137 lb 11/23/2010 Physician Brazil
Primary
Secondary
Concomitant
Shock Life Threatening 10/5/2010 75 Male 12/3/2010 Physician Japan
Primary
Secondary
Concomitant
Swelling Other Serious 47 Male 12/6/2010 Consumer United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 40 Male 12/29/2010 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 12/30/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2006 64 Male 150 lb 12/31/2010 United States
Primary
Secondary
Concomitant
Pain Other Serious 12/31/2010 Physician United States
Primary
Concomitant
Anaemia Death 9/9/2010 63 Female 1/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 9/9/2010 63 Female 1/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vocal Cord Paralysis Hospitalization Male 1/24/2011 Other Health Professional United States
Primary
Secondary
Cerebrovascular Accident Hospitalization 1/1/2010 78 Male 1/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Other Serious 9/9/2010 63 Female 1/2/2011 United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 8/9/2010 70 Male 99 lb 2/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Fatigue Death 9/9/2010 63 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Other Serious 9/9/2010 63 Female 2/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Generalised Other Serious 28 Male 2/4/2011 Other Health Professional United States
Primary
Secondary
Nausea Death 9/9/2010 70 Male 107 lb 2/7/2011 Physician Japan
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/18/2011 68 Male 2/21/2011 Physician Italy
Primary
Secondary
Concomitant
Paraesthesia Other Serious 1/1/2009 68 Female 2/8/2011 Japan
Primary
Secondary
Transient Ischaemic Attack Hospitalization 1/1/2010 70 Male 4/18/2011 Physician Italy
Primary
Secondary
Concomitant
Vomiting Other Serious 1/18/2011 68 Male 4/18/2011 Consumer Italy
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 1/1/2010 70 Male 5/18/2011 Physician Italy
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 5/19/2011 56 Female 180 lb 5/19/2011 Pharmacist United States
Primary
Concomitant
Confusional State Hospitalization 3/29/2011 62 Female 137 lb 5/24/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/17/2010 75 Male 5/26/2011 Physician France
Primary
Concomitant
Segmented Hyalinising Vasculitis Hospitalization 9/17/2010 75 Male 6/2/2011 Physician France
Primary
Concomitant
Leukocytosis Hospitalization 1/1/2005 40 Male 6/7/2011 Lawyer United States
Primary
Concomitant
Hypotension Life Threatening 10/4/2004 57 Female 86 lb 6/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haematoma Other Serious 47 Male 207 lb 7/1/2011 Physician United Kingdom
Primary
Secondary
Interacting
Skin Exfoliation Death 3/18/2011 80 Male 7/1/2011 Physician Portugal
Primary
Concomitant
Skin Exfoliation Death 3/18/2011 80 Male 7/7/2011 Physician Portugal
Primary
Concomitant
Rash Other Serious 9/1/2010 68 Male 7/8/2011 Other Health Professional United States
Primary
Concomitant
Extremity Necrosis Other Serious 72 Female 7/11/2011 Physician Italy
Primary
Concomitant
Decreased Appetite Other Serious 3/18/2011 80 Male 7/15/2011 Physician Portugal
Primary
Concomitant
Hypokalaemia Other Serious 1/8/2007 54 Female 7/21/2011 Lawyer United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 3/18/2011 80 Male 7/21/2011 Physician Portugal
Primary
Concomitant
Loss Of Consciousness Hospitalization 6/1/2006 64 Male 150 lb 7/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Metastases To Bone Other Serious 1/1/2005 40 Male 8/1/2011 Lawyer United States
Primary
Concomitant
Amnesia Hospitalization 1/8/2007 54 Female 8/2/2011 Physician United States
Primary
Secondary
Concomitant
Burning Sensation Other Serious 9/1/2010 68 Male 8/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Perforation Death 1/1/2011 60 Female 93 lb 8/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Contusion Other Serious 47 Male 249 lb 8/22/2011 Physician United Kingdom
Primary
Concomitant
Interacting
Pancreatic Carcinoma Death 1/1/2011 58 Female 101 lb 8/29/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 47 Male 8/22/2011 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2010 75 Male 8/31/2011 Physician France
Primary
Concomitant
Nasal Congestion Other Serious 1/8/2007 54 Female 9/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 1/8/2007 54 Female 10/6/2011 Consumer United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 1/8/2007 54 Female 10/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 10/14/2011 Physician United States
Primary
Secondary
Paraesthesia Other Serious 10/1/2011 59 Male 10/25/2011 Physician Viet Nam
Primary
Concomitant
Fall Hospitalization 7/1/2011 10/27/2011 Physician United States
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 11/1/2011 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/8/2007 54 Female 11/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious 6/1/2006 64 Male 150 lb 11/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fall Death 7/1/2011 Female 11/7/2011 Physician United States
Primary
Secondary
Concomitant
Restrictive Pulmonary Disease Hospitalization 1/8/2007 54 Female 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 11/10/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data