Carboplatin combined with Sorafenib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neutropenic Sepsis Hospitalization 12/6/2005 69 Female 148 lb 1/27/2006 United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/21/2006 57 Male 190 lb 2/27/2006 Netherlands
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/21/2006 57 Male 190 lb 3/1/2006 Netherlands
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 12/6/2005 69 Female 148 lb 3/15/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 3/28/2006 United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 12/6/2005 69 Female 148 lb 3/29/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 3/8/2006 77 Female 170 lb 4/17/2006 Physician United States
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Other Serious 3/8/2006 77 Female 170 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 10/6/2005 64 Female 203 lb 4/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Other Serious 3/8/2006 77 Female 4/27/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/8/2006 77 Female 5/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 2/10/2006 73 Male 169 lb 5/17/2006 Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/15/2006 77 Female 170 lb 5/17/2006 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/21/2006 57 Male 190 lb 6/5/2006 Netherlands
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/21/2006 53 Male 4/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/14/2006 54 Male 164 lb 6/26/2006 United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 3/14/2006 54 Male 164 lb 7/6/2006 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 2/15/2006 77 Female 177 lb 7/20/2006 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/8/2006 77 Female 7/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 10/6/2005 64 Female 203 lb 7/27/2006 Germany
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 3/14/2006 55 Male 163 lb 8/4/2006 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 3/14/2006 55 Male 163 lb 8/4/2006 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 7/25/2006 71 Male 134 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 12/12/2005 74 Female 157 lb 8/29/2006 Other Health Professional United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 7/25/2006 71 Male 134 lb 8/31/2006 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/21/2006 58 Male 190 lb 9/26/2006 Physician Netherlands
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/8/2006 59 Male 225 lb 9/26/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/14/2006 55 Male 163 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 10/6/2005 64 Female 203 lb 10/9/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 12/12/2005 74 Female 157 lb 10/11/2006 Other Health Professional United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 12/6/2005 70 Female 148 lb 10/20/2006 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 3/15/2006 40 Female 10/26/2006 Physician Germany
Primary
Secondary
Concomitant
Electrocardiogram St Segment Elevation Hospitalization 3/4/2006 62 Male 146 lb 11/3/2006 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 6/16/2006 44 Male 154 lb 11/3/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Petechiae Hospitalization 10/22/2006 63 Female 11/10/2006 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Limb Hospitalization 3/15/2006 40 Female 11/21/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/28/2006 Physician United States
Primary
Secondary
Concomitant
Neutropenia Life Threatening 1/23/2006 62 Male 146 lb 11/28/2006 Physician Germany
Primary
Secondary
Tachyarrhythmia Hospitalization 11/20/2006 69 Female 148 lb 12/4/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/18/2006 70 Female 99 lb 12/6/2006 Physician Canada
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/30/2006 Male 12/7/2006 Physician United Kingdom
Primary
Secondary
Transient Ischaemic Attack Hospitalization 3/21/2006 45 Male 141 lb 12/8/2006 Physician Germany
Primary
Secondary
Pancytopenia Hospitalization 10/22/2006 63 Female 12/8/2006 Physician United States
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 10/22/2006 63 Female 12/13/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Vocal Cord Paralysis Hospitalization 10/22/2006 63 Female 126 lb 12/21/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/12/2006 74 Female 101 lb 12/22/2006 Physician Belgium
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/22/2006 77 Male 1/8/2007 Other Health Professional Germany
Primary
Secondary
Deep Vein Thrombosis Hospitalization 1/5/2007 60 Male 134 lb 1/12/2007 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 61 Male 1/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/31/2006 61 Male 132 lb 1/22/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2005 72 Female 101 lb 1/22/2007 Physician Belgium
Primary
Secondary
Concomitant
Peripheral Coldness Hospitalization 1/3/2007 60 Male 134 lb 1/24/2007 Physician Canada
Primary
Secondary
Concomitant
Peripheral Coldness Hospitalization 1/3/2007 60 Male 134 lb 1/29/2007 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/31/2006 61 Male 132 lb 2/5/2007 Physician United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 11/20/2006 54 Male 212 lb 2/6/2007 Physician Netherlands
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 10/22/2006 63 Female 126 lb 2/6/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 61 Male 172 lb 2/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/18/2006 70 Female 99 lb 2/21/2007 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 61 Male 172 lb 2/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/18/2006 70 Female 99 lb 2/26/2007 Physician Canada
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/20/2006 54 Male 212 lb 2/26/2007 Physician Netherlands
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization 9/10/2006 66 Male 132 lb 2/28/2007 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 9/10/2006 66 Male 132 lb 3/7/2007 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 61 Male 172 lb 3/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/20/2006 54 Male 212 lb 3/12/2007 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2005 72 Female 101 lb 3/20/2007 Physician Belgium
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/7/2007 68 Male 112 lb 4/3/2007 Physician Brazil
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 3/16/2007 52 Male 150 lb 4/3/2007 Physician Argentina
Primary
Secondary
Concomitant
Rash Life Threatening 1/24/2007 61 Male 126 lb 4/5/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 3/7/2007 68 Male 112 lb 4/11/2007 Physician Brazil
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2005 72 Female 101 lb 4/23/2007 Physician Belgium
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/23/2007 54 Female 119 lb 4/24/2007 Physician Netherlands
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 3/7/2007 68 Male 112 lb 4/25/2007 Physician Brazil
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 3/7/2007 68 Male 112 lb 5/2/2007 Physician Brazil
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/20/2006 54 Male 212 lb 5/3/2007 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/18/2006 70 Female 99 lb 5/7/2007 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/4/2007 60 Male 234 lb 5/14/2007 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 3/16/2007 52 Male 150 lb 5/18/2007 Physician Argentina
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/4/2007 60 Male 234 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/17/2006 60 Male 172 lb 5/25/2007 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/1/2007 84 Male 150 lb 6/7/2007 Physician Germany
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 5/1/2007 68 Female 62 lb 6/14/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/12/2007 66 Male 6/25/2007 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/23/2007 54 Female 119 lb 7/5/2007 Physician Netherlands
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 5/25/2007 68 Female 62 lb 7/17/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/23/2007 54 Female 119 lb 7/18/2007 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/17/2006 60 Male 172 lb 7/20/2007 United Kingdom
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 4/18/2007 71 Male 152 lb 7/23/2007 Physician Belgium
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 4/18/2007 71 Male 152 lb 8/1/2007 Physician Belgium
Primary
Secondary
Concomitant
Urinary Retention Other Serious 5/2/2007 48 Male 183 lb 8/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/17/2006 60 Male 172 lb 8/8/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/17/2006 60 Male 172 lb 8/23/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/17/2006 60 Male 172 lb 9/10/2007 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/31/2006 61 Male 132 lb 9/14/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/1/2007 84 Male 150 lb 9/14/2007 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Death 8/29/2007 68 Male 143 lb 10/11/2007 Physician Brazil
Primary
Secondary
Concomitant
Dyspnoea Other Serious 10/15/2007 48 Male 121 lb 10/18/2007 Physician Singapore
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/25/2007 67 Male 161 lb 10/19/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/15/2007 48 Male 121 lb 10/22/2007 Physician Singapore
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 9/25/2007 67 Male 161 lb 10/23/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/17/2006 60 Male 172 lb 11/13/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Other Serious 5/2/2007 57 Male 183 lb 11/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/25/2007 67 Male 161 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 10/2/2007 63 Female 126 lb 11/20/2007 Physician Hong Kong
Primary
Secondary
Concomitant
Ileus Hospitalization 2/24/2007 56 Male 11/23/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Ileus Hospitalization 2/24/2007 56 Male 11/26/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Urinary Retention Other Serious 5/2/2007 57 Male 183 lb 11/30/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/17/2006 60 Male 172 lb 12/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 4/18/2007 71 Male 152 lb 12/6/2007 Physician Belgium
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 10/2/2007 63 Female 123 lb 12/6/2007 Physician Hong Kong
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/15/2006 78 Female 170 lb 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 2/15/2006 77 Female 12/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Peripheral Coldness Hospitalization 1/3/2007 60 Male 134 lb 12/20/2007 Physician Canada
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 10/2/2007 63 Female 123 lb 12/20/2007 Physician Hong Kong
Primary
Secondary
Concomitant
Rash Other Serious 12/13/2007 55 Female 119 lb 1/11/2008 Physician China
Primary
Secondary
Renal Failure Other Serious 9/25/2007 67 Male 161 lb 1/11/2008 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 12/11/2007 55 Female 119 lb 1/15/2008 Physician China
Primary
Secondary
Respiratory Failure Death 9/29/2007 68 Male 143 lb 1/16/2008 Physician Brazil
Primary
Secondary
Concomitant
Peripheral Coldness Hospitalization 1/3/2007 60 Male 134 lb 1/16/2008 Physician Canada
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 4/18/2007 71 Male 152 lb 1/17/2008 Physician Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/15/2006 59 Male 225 lb 2/4/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 5/2/2007 57 Male 183 lb 2/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Peripheral Coldness Hospitalization 1/3/2007 60 Male 134 lb 2/11/2008 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 4/6/2007 45 Male 3/3/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/23/2006 56 Male 3/4/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/11/2006 75 Male 170 lb 3/4/2008 Physician Germany
Primary
Secondary
Concomitant
Rash Other Serious 3/7/2007 78 Female 161 lb 3/4/2008 United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/18/2007 70 Female 110 lb 3/4/2008 Physician Brazil
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 2/15/2007 53 Male 3/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/24/2007 67 Male 159 lb 3/4/2008 Physician Italy
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/20/2007 62 Female 106 lb 3/4/2008 Physician Belgium
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Hospitalization 4/27/2007 70 Male 220 lb 3/4/2008 Physician Germany
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/14/2007 57 Female 99 lb 3/4/2008 Physician Germany
Primary
Secondary
Concomitant
Stomatitis Life Threatening 10/25/2006 65 Female 110 lb 3/4/2008 Physician Italy
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 12/18/2006 41 Male 223 lb 3/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 4/6/2007 45 Male 192 lb 3/4/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/23/2006 56 Male 99 lb 3/4/2008 Physician Germany
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 12/25/2006 49 Female 3/4/2008 United Kingdom
Primary
Secondary
Rash Hospitalization 4/13/2007 67 Male 141 lb 3/4/2008 Physician Argentina
Primary
Secondary
Concomitant
Hypertension Other Serious 2/16/2007 59 Female 234 lb 3/4/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/6/2007 81 Female 121 lb 3/4/2008 Physician Brazil
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 7/4/2006 75 Female 3/5/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 4/18/2007 71 Male 152 lb 3/5/2008 Physician Belgium
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/1/2007 84 Male 150 lb 3/11/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/23/2006 56 Male 99 lb 3/17/2008 Physician Germany
Primary
Secondary
Concomitant

Drug Data