Carboplatin combined with Iressa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pleural Effusion Other Serious 11/21/2005 75 Male 117 lb 1/2/2006 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Other Serious 12/1/2005 76 Male 1/4/2006 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 9/8/2005 47 Male 128 lb 1/5/2006 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 12/6/2005 78 Male 115 lb 1/6/2006 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 12/6/2005 78 Male 115 lb 1/10/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 8/24/2005 47 Female 90 lb 1/11/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 9/30/2004 Male 151 lb 1/24/2006 Physician Australia
Primary
Secondary
Concomitant
Radiation Myelopathy Other Serious 10/8/2004 60 Female 234 lb 1/25/2006 Physician Australia
Primary
Secondary
Pneumonia Bacterial Hospitalization 12/1/2005 76 Male 109 lb 1/25/2006 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 12/6/2005 78 Male 115 lb 2/3/2006 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 1/23/2006 71 Male 125 lb 2/6/2006 Physician Japan
Primary
Concomitant
Pleural Effusion Death 11/21/2005 75 Male 117 lb 2/7/2006 Physician Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/15/2005 57 Male 152 lb 2/10/2006 Physician Japan
Primary
Concomitant
Pneumonitis Other Serious 9/30/2004 70 Male 151 lb 2/13/2006 Physician Australia
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 10/4/2005 75 Male 130 lb 2/14/2006 Physician Japan
Primary
Concomitant
Pneumonitis Other Serious 9/30/2004 70 Male 151 lb 2/14/2006 Physician Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 11/14/2005 64 Female 95 lb 2/15/2006 Physician Japan
Primary
Concomitant
Radiation Myelopathy Other Serious 10/27/2004 60 Female 234 lb 2/16/2006 Physician Australia
Primary
Secondary
Hepatic Function Abnormal Other Serious 10/7/2005 78 Female 115 lb 2/22/2006 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 12/27/2005 58 Female 2/23/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 8/1/2005 47 Female 90 lb 3/1/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 2/12/2004 67 Female 207 lb 3/7/2006 Physician France
Primary
Secondary
Concomitant
Acute Lymphocytic Leukaemia Other Serious 9/19/2003 44 Female 3/7/2006 Physician France
Primary
Secondary
Concomitant
Sepsis Other Serious 10/4/2005 75 Male 130 lb 3/10/2006 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 1/19/2006 55 Male 117 lb 3/10/2006 Physician Japan
Primary
Concomitant
Purpura Hospitalization 12/27/2005 58 Female 3/15/2006 Physician Japan
Primary
Concomitant
Mental Status Changes Hospitalization 6/15/2005 60 Male 116 lb 7/14/2005 Physician United States
Primary
Secondary
Concomitant
Radiation Myelopathy Other Serious 9/22/2004 60 Female 234 lb 3/17/2006 Physician Australia
Primary
Secondary
Shock Life Threatening 1/30/2006 48 Female 83 lb 3/17/2006 Physician Japan
Primary
Concomitant
Stupor Life Threatening 1/30/2006 48 Female 83 lb 3/21/2006 Physician Japan
Primary
Concomitant
Oesophagitis Hospitalization 11/5/2004 76 Female 3/27/2006 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/15/2006 47 Male 166 lb 4/13/2006 Physician Canada
Primary
Concomitant
Platelet Count Decreased Death 4/11/2006 Male 4/25/2006 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 2/3/2006 69 Female 99 lb 4/28/2006 Physician Japan
Primary
Concomitant
Rash Hospitalization 12/18/2004 69 Female 84 lb 4/28/2006 Physician Japan
Primary
Concomitant
Dementia Alzheimer's Type Other Serious 1/1/2006 64 Female 4/21/2006 Japan
Primary
Concomitant
Skin Infection Hospitalization 4/27/2006 69 Female 159 lb 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Pseudomonas Infection Hospitalization 4/9/2006 55 Male 203 lb 5/12/2006 Physician United States
Primary
Secondary
Concomitant
Hypoxia Hospitalization 5/12/2004 76 Male 5/16/2006 Physician Japan
Primary
Concomitant
Urge Incontinence Other Serious 4/22/2006 67 Male 152 lb 5/26/2006 Physician Belgium
Primary
Concomitant
Thrombocytopenia Other Serious 2/15/2006 47 Male 166 lb 5/30/2006 Physician Canada
Primary
Concomitant
Chemical Cystitis Other Serious 4/22/2006 67 Male 152 lb 6/1/2006 Physician Belgium
Primary
Concomitant
Thrombocytopenia Other Serious 2/15/2006 47 Male 166 lb 6/6/2006 Physician Canada
Primary
Concomitant
Rash Hospitalization 12/18/2004 69 Female 84 lb 6/8/2006 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/24/2005 54 Female 6/15/2006 Physician Japan
Primary
Concomitant
Neoplasm Recurrence Disability 11/5/2004 72 Male 6/21/2006 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Disability 2/7/2006 52 Female 97 lb 6/26/2006 Physician Japan
Primary
Concomitant
Pharyngeal Fistula Hospitalization 6/12/2006 48 Male 143 lb 6/26/2006 Physician Australia
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2/3/2006 69 Female 99 lb 6/26/2006 Physician Japan
Primary
Concomitant
Pharyngeal Fistula Hospitalization 6/12/2006 48 Male 143 lb 6/30/2006 Physician Australia
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 5/9/2006 63 Male 138 lb 7/7/2006 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 5/21/2005 67 Male 7/26/2006 Physician Korea, Republic Of
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/23/2006 71 Male 123 lb 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Bronchopneumonia Death 2/23/2006 72 Male 123 lb 8/3/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/9/2006 55 Male 203 lb 8/15/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/9/2006 55 Male 203 lb 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Lymphangiosis Carcinomatosa Disability 2/7/2006 52 Female 97 lb 9/5/2006 Physician Japan
Primary
Concomitant
Acute Respiratory Failure Death 70 Female 9/18/2006 Physician Japan
Primary
Concomitant
Tumour Associated Fever Other Serious 6/30/2006 44 Male 162 lb 9/25/2006 Other Health Professional United States
Primary
Concomitant
Malignant Neoplasm Progression Death 8/26/2006 76 Female 106 lb 10/9/2006 Physician Japan
Primary
Concomitant
Pleural Effusion Death 8/26/2006 76 Female 106 lb 10/12/2006 Physician Japan
Primary
Concomitant
Vomiting Other Serious 4/5/2006 62 Female 10/13/2006 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 6/12/2006 66 Female 126 lb 10/24/2006 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/13/2006 73 Male 10/26/2006 Physician Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 9/14/2006 75 Female 106 lb 10/31/2006 Physician Japan
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 72 Female 11/1/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 9/14/2006 75 Female 106 lb 11/16/2006 Physician Japan
Primary
Concomitant
Leukaemia Other Serious 11/6/2006 Female 11/16/2006 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 11/1/2006 61 Female 11/30/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/1/2006 61 Female 121 lb 12/14/2006 Physician Japan
Primary
Concomitant
Acute Promyelocytic Leukaemia Life Threatening 3/1/2004 51 Female 12/14/2006 Other Health Professional Japan
Primary
Concomitant
Spinal Disorder Other Serious 9/18/2006 51 Male 150 lb 12/21/2006 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 6/20/2006 66 Female 126 lb 12/21/2006 Physician Japan
Primary
Concomitant
Skin Ulcer Other Serious 8/1/2006 52 Male 12/21/2006 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 10/24/2006 76 Male 117 lb 1/2/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/20/2006 61 Female 121 lb 1/2/2007 Physician Japan
Primary
Concomitant
Liver Disorder Death 12/25/2006 79 Female 121 lb 1/31/2007 Physician Japan
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 10/24/2006 76 Male 117 lb 2/2/2007 Physician Japan
Primary
Concomitant
Nasal Congestion Hospitalization 11/14/2006 37 Female 106 lb 2/20/2007 Physician Japan
Primary
Secondary
Concomitant
Nodule Female 2/28/2007 Other Health Professional United States
Primary
Secondary
Lung Disorder Other Serious 40 Female 3/8/2007 Physician Japan
Primary
Concomitant
Rhinorrhoea Hospitalization 11/14/2006 37 Female 106 lb 3/13/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 1/7/2004 70 Male 148 lb 4/16/2004 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 68 Male 185 lb 2/11/2005 United States
Primary
Concomitant
Lung Disorder Death 1/19/2007 72 Female 90 lb 3/14/2007 Physician Japan
Primary
Concomitant
Respiratory Disorder Other Serious 8/27/2004 50 Female 10/12/2004 Other Health Professional United States
Primary
Secondary
Large Intestinal Ulcer Hospitalization 3/9/2007 74 Female 75 lb 4/4/2007 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 1/1/2007 74 Female 75 lb 4/19/2007 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 2/24/2007 57 Male 4/23/2007 Physician Italy
Primary
Concomitant
Lung Disorder Death 1/19/2007 72 Female 90 lb 4/25/2007 Physician Japan
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Disability 1/3/2007 64 Male 157 lb 5/21/2007 Physician Japan
Primary
Concomitant
Leukoencephalopathy Other Serious 50 Male 6/20/2007 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Death 6/8/2007 80 Female 7/17/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal 4/11/2007 71 Female 115 lb 7/25/2007 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 1/28/2003 66 Male 8/3/2007 Consumer Australia
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/8/2007 80 Female 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 7/6/2007 73 Male 130 lb 8/13/2007 Physician Japan
Primary
Concomitant
Mucous Membrane Disorder Hospitalization 7/25/2007 72 Female 77 lb 8/16/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/25/2007 73 Female 77 lb 8/17/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 7/6/2007 73 Male 130 lb 8/27/2007 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 1/22/2007 61 Female 130 lb 9/4/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 7/6/2007 73 Male 130 lb 9/10/2007 Physician Japan
Primary
Concomitant
Multi-organ Failure Hospitalization 8/27/2007 75 Male 9/13/2007 Physician Korea, Republic Of
Primary
Concomitant
Thrombocytopenia Other Serious 8/17/2007 79 Female 95 lb 11/2/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/17/2007 79 Female 95 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/11/2008 73 Female 1/26/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 11/29/2007 73 Female 104 lb 2/9/2008 Physician Japan
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Disability 1/3/2007 64 Male 157 lb 2/11/2008 Physician Japan
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Disability 1/3/2007 64 Male 157 lb 2/14/2008 Physician Japan
Primary
Concomitant
Hepatitis Fulminant Hospitalization 2/15/2007 63 Male 3/3/2008 Physician Korea, Republic Of
Primary
Concomitant
Hepatitis Fulminant Hospitalization 2/15/2007 63 Male 3/17/2008 Physician Korea, Republic Of
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 7/8/2008 76 Female 8/4/2008 Other Health Professional Philippines
Primary
Secondary
Concomitant
Rash Papular Other Serious 5/5/2008 61 Female 1/28/2009 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Death 12/1/2008 Male 2/17/2009 Physician Japan
Primary
Concomitant
Swelling Other Serious 1/12/2009 Male 124 lb 2/20/2009 Physician Thailand
Primary
Concomitant
Therapeutic Response Decreased Death 1/24/2009 80 Female 117 lb 3/17/2009 Other Health Professional Japan
Primary
Concomitant
Pneumonia Hospitalization 10/10/2002 69 Female 3/27/2009 Other Health Professional Japan
Primary
Concomitant
Metastases To Lung Other Serious 5/5/2008 61 Female 88 lb 3/23/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 3/26/2009 64 Male 143 lb 4/8/2009 Physician Australia
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 3/26/2009 64 Male 143 lb 4/15/2009 Physician Australia
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 3/26/2009 64 Male 143 lb 5/5/2009 Physician Australia
Primary
Secondary
Lung Disorder Life Threatening 6/10/2009 68 Female 7/1/2009 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 2/17/2009 78 Female 99 lb 7/8/2009 Physician Japan
Primary
Concomitant
Haemoptysis Hospitalization 7/23/2004 62 Male 150 lb 7/9/2009 Physician Korea, Republic Of
Primary
Concomitant
Multi-organ Failure Life Threatening 9/3/2007 75 Male 7/31/2009 Physician Korea, Republic Of
Primary
Concomitant
Vomiting Other Serious 2/13/2008 Female 161 lb 8/18/2009 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 8/18/2009 60 Male 10/30/2009 Physician Japan
Primary
Concomitant
Rash Death 1/1/2005 80 Female 117 lb 12/14/2009 Physician Japan
Primary
Concomitant
Ileus Paralytic Hospitalization 4/26/2006 54 Male 1/27/2010 Other Health Professional China
Primary
Concomitant
Ileus Paralytic Hospitalization 4/26/2006 54 Male 2/2/2010 Other Health Professional China
Primary
Concomitant
Vomiting Other Serious 2/13/2008 75 Female 161 lb 4/8/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/17/2010 70 Male 6/7/2010 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 5/17/2010 69 Male 6/18/2010 Physician Japan
Primary
Secondary
Serotonin Syndrome Hospitalization 7/1/2010 57 Female 7/26/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 3/24/2007 60 Female 8/27/2010 Physician Japan
Primary
Secondary
Vomiting Hospitalization 7/1/2010 57 Female 115 lb 8/31/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 3/24/2007 60 Female 108 lb 9/10/2010 Physician Japan
Primary
Secondary
Pneumothorax Other Serious 1/1/2010 66 Male 130 lb 10/15/2010 Physician Japan
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Life Threatening 2/18/2009 60 Female 108 lb 10/19/2010 Physician Japan
Primary
Secondary
Pneumothorax Life Threatening 3/16/2010 67 Male 130 lb 12/16/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Disability 12/15/2010 67 Male 119 lb 4/28/2011 Physician Japan
Primary
Secondary
Concomitant
Pruritus Disability 12/15/2010 67 Male 119 lb 4/28/2011 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Disability 12/15/2010 67 Male 119 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/18/2011 72 Female 117 lb 7/26/2011 Physician Japan
Primary
Concomitant
Small Intestinal Perforation Death 1/1/2011 60 Female 93 lb 8/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious Male 11/10/2011 Physician Japan
Primary
Secondary
Pneumonia Death 8/20/2011 64 Male 12/6/2011 Physician Korea, Republic Of
Primary
Secondary
Pneumonia Death 8/20/2011 64 Male 12/13/2011 Physician Korea, Republic Of
Primary
Secondary
Pneumopericardium Other Serious 11/1/2011 68 Male 110 lb 4/10/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumopericardium Other Serious 11/1/2011 68 Male 110 lb 5/8/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data