Carboplatin combined with Herceptin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Debridement Other Serious 4/1/2005 48 Female 117 lb 1/10/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/1/2005 65 Female 1/13/2006 Consumer United States
Primary
Concomitant
Erythema Other Serious 1/28/2005 24 Female 269 lb 2/6/2006 Consumer United States
Primary
Concomitant
Neutropenia Hospitalization 2/5/2006 51 Female 2/28/2006 Other Health Professional Canada
Primary
Secondary
Neutropenia Hospitalization 2/5/2006 51 Female 3/16/2006 United Kingdom
Primary
Secondary
Vomiting Hospitalization 2/24/2006 Female 148 lb 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 4/12/2005 33 Female 137 lb 4/11/2006 Other Health Professional United States
Primary
Concomitant
Vomiting 9/21/2005 51 Female 267 lb 4/11/2006 Consumer United States
Primary
Concomitant
Groin Pain 11/8/2005 78 Female 4/11/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 3/1/2006 69 Female 190 lb 4/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 4/1/2005 25 Female 132 lb 5/5/2006 France
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 3/15/2005 25 Female 4/6/2006 France
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 4/1/2003 48 Female 138 lb 5/3/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 52 Female 5/26/2006 Consumer Spain
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 52 Female 6/2/2006 Spain
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 52 Female 7/19/2006 Other Health Professional Spain
Primary
Secondary
Multi-organ Failure Hospitalization 52 Female 7/27/2006 Other Health Professional Spain
Primary
Secondary
Multi-organ Failure Hospitalization 52 Female 7/27/2006 Spain
Primary
Secondary
Hyperammonaemia Other Serious 52 Female 8/22/2006 Spain
Primary
Secondary
Post Procedural Complication Other Serious 52 Female 8/29/2006 Spain
Primary
Secondary
Hypersensitivity Other Serious 10/19/2005 77 Female 6/6/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Life Threatening 10/23/2005 38 Female 6/6/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/27/2006 37 Female 9/11/2006 Pharmacist United States
Primary
Secondary
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Life Threatening 4/18/2006 57 Female 195 lb 10/2/2006 United States
Primary
Concomitant
Vomiting Hospitalization 8/27/2006 37 Female 185 lb 10/3/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sinus Congestion Hospitalization 9/5/2006 52 Female 143 lb 10/23/2006 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 5/8/2002 Female 181 lb 10/30/2006 Other Health Professional South Africa
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 43 Female 11/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/13/2006 56 Female 190 lb 11/18/2006 Other Health Professional Brazil
Primary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 11/21/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/6/2003 54 Female 11/15/2006 United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 11/17/2006 54 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Other Serious 10/15/2006 60 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 10/5/2006 58 Female 119 lb 12/11/2006 United States
Primary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 11/17/2006 54 Female 1/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 1/12/2007 United States
Primary
Secondary
Concomitant
Unwanted Awareness During Anaesthesia Other Serious 5/1/2003 56 Female 2/12/2007 Italy
Primary
Concomitant
Myalgia Hospitalization 4/29/2006 81 Female 130 lb 2/28/2007 Physician United States
Primary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 3/8/2007 United States
Primary
Secondary
Concomitant
Infusion Related Reaction 1/1/2007 Female 167 lb 3/19/2007 Pharmacist United States
Primary
Concomitant
Pancytopenia Life Threatening 12/1/2006 37 Female 4/12/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/9/2007 58 Female 209 lb 4/20/2007 Consumer France
Primary
Secondary
Concomitant
Nephritis Haemorrhagic Life Threatening 4/25/2007 50 Female 5/8/2007 Other Health Professional United States
Primary
Concomitant
Nephritis Haemorrhagic Life Threatening 4/25/2007 57 Female 5/14/2007 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Other Serious 4/1/2007 Female 5/14/2007 Physician United Kingdom
Primary
Concomitant
Transaminases Increased Other Serious 4/1/2007 Female 5/22/2007 Physician United Kingdom
Primary
Concomitant
Transaminases Increased Other Serious 4/1/2007 Female 5/31/2007 Physician United Kingdom
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 7/15/2006 75 Female 6/20/2007 Other Health Professional France
Primary
Secondary
Wound Debridement Hospitalization 11/1/2004 52 Female 6/29/2007 France
Primary
Concomitant
Acute Leukaemia Hospitalization 7/15/2006 75 Female 7/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Leukaemia Hospitalization 7/15/2006 75 Female 8/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Muscle Contractions Involuntary Other Serious Female 8/10/2007 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 7/16/2007 35 Female 150 lb 9/10/2007 Consumer Netherlands
Primary
Concomitant
Muscle Contractions Involuntary Other Serious Female 9/13/2007 Pharmacist United States
Primary
Concomitant
Disorientation Other Serious 8/6/2007 55 Female 135 lb 9/28/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 11/26/2004 Female 296 lb 10/2/2007 Other Health Professional United States
Primary
Concomitant
Hepatic Cirrhosis Other Serious Female 10/2/2007 Physician United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Other Serious Female 10/2/2007 Physician United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 7/8/2007 59 Female 140 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/2/2007 62 Female 11/7/2007 Other Health Professional France
Primary
Secondary
Pericardial Effusion Other Serious 44 Female 11/7/2007 Physician United States
Primary
Concomitant
Pericardial Effusion Other Serious 44 Female 11/8/2007 Physician United States
Primary
Concomitant
Vomiting Life Threatening 7/2/2007 62 Female 11/13/2007 Other Health Professional France
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 10/29/2007 50 Female 158 lb 11/19/2007 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 7/2/2007 Female 11/29/2007 Other Health Professional France
Primary
Secondary
Pericardial Effusion Other Serious 10/15/2007 Female 163 lb 12/3/2007 Physician United States
Primary
Concomitant
Pericardial Effusion Other Serious 11/2/2007 Female 164 lb 12/14/2007 Physician United States
Primary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 12/17/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/29/2007 50 Female 348 lb 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Toxicity Other Serious 1/1/2003 58 Female 12/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Muscle Contractions Involuntary Other Serious Female 1/15/2008 Pharmacist United States
Primary
Concomitant
Pericardial Effusion Other Serious 10/15/2007 Female 163 lb 1/24/2008 Physician United States
Primary
Concomitant
Pericardial Effusion Other Serious 10/15/2007 Female 164 lb 1/24/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Female 3/13/2008 Consumer United States
Primary
Concomitant
Clostridial Infection Hospitalization 12/10/2007 3/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus Other Serious 2/1/2008 44 Female 3/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Diarrhoea Hospitalization 12/10/2007 41 3/14/2008 United Kingdom
Primary
Secondary
Concomitant
Clostridial Infection Hospitalization 12/10/2007 41 3/12/2008 United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/24/2008 Female 197 lb 5/2/2008 Physician United States
Primary
Concomitant
Intestinal Perforation Other Serious Female 5/12/2008 Physician United Kingdom
Primary
Concomitant
Ejection Fraction Decreased Other Serious 12/6/2007 Male 5/15/2008 Pharmacist United States
Primary
Concomitant
Intestinal Perforation Other Serious Female 5/21/2008 Physician United Kingdom
Primary
Concomitant
Duodenal Ulcer Perforation Life Threatening 4/25/2008 Female 163 lb 6/5/2008 Consumer United Kingdom
Primary
Concomitant
Wheezing Other Serious 2/26/2008 47 Female 3/27/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 3/27/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 54 Female 180 lb 3/27/2008 Physician United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious Female 7/3/2008 Consumer United Kingdom
Primary
Secondary
Radiation Fibrosis Other Serious Female 7/3/2008 Physician Germany
Primary
Concomitant
Radiation Fibrosis Other Serious Female 7/18/2008 Physician Germany
Primary
Concomitant
Carcinoembryonic Antigen Increased Other Serious Female 8/22/2008 Consumer United States
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 9/12/2008 Female 136 lb 10/1/2008 Physician United States
Primary
Secondary
Herpes Zoster Hospitalization 9/12/2008 Female 136 lb 10/8/2008 Physician United States
Primary
Secondary
Pain In Jaw Other Serious Female 10/10/2008 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2001 Female 152 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious 5/17/2008 Female 12/18/2008 Physician United States
Primary
Secondary
Concomitant
Deafness Other Serious 72 Female 1/15/2009 Consumer United States
Primary
Secondary
Concomitant
Skin Exfoliation Disability 12/10/2008 43 Female 1/26/2009 Physician Australia
Primary
Concomitant
Acute Myeloid Leukaemia Life Threatening 10/1/2008 44 Female 1/27/2009 Physician France
Primary
Secondary
Scar Other Serious Female 1/27/2009 Consumer United Kingdom
Primary
Concomitant
Pathological Fracture Other Serious 1/28/2009 Other Health Professional United States
Primary
Concomitant
Acute Myeloid Leukaemia Life Threatening 44 Female 2/2/2009 Physician France
Primary
Secondary
Concomitant
Osteoporotic Fracture Other Serious Female 2/5/2009 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 2/10/2009 Female 280 lb 2/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/1/2009 54 Female 2/20/2009 Other Health Professional United States
Primary
Secondary
Neutropenia Other Serious 2/1/2009 54 Female 2/24/2009 Other Health Professional United States
Primary
Secondary
Neutropenia Other Serious 2/1/2009 54 Female 3/3/2009 Other Health Professional United States
Primary
Secondary
Neutropenia Other Serious 1/1/2009 54 Female 3/4/2009 Other Health Professional United States
Primary
Secondary
Neutropenia Other Serious 1/1/2009 54 Female 3/4/2009 Other Health Professional United States
Primary
Secondary
Neutropenia Other Serious 1/1/2009 54 Female 2/18/2009 United States
Primary
Secondary
Thrombocytopenia Hospitalization Female 3/18/2009 Consumer United States
Primary
Concomitant
Transaminases Increased Other Serious 4/1/2007 Female 3/18/2009 Physician Greece
Primary
Concomitant
Skin Exfoliation Other Serious 12/29/2008 Female 3/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Scar Other Serious Female 3/30/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Thrombosis Hospitalization 76 Female 4/9/2009 Consumer United States
Primary
Concomitant
Liver Disorder Other Serious 52 Female 4/14/2009 Consumer United States
Primary
Concomitant
Central Line Infection Hospitalization 4/13/2009 56 Female 257 lb 4/14/2009 Other Health Professional United States
Primary
Secondary
Oesophagitis 4/23/2009 Physician United States
Primary
Secondary
Tricuspid Valve Incompetence Other Serious 2/5/2009 Female 4/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 38 Female 4/28/2009 Physician United States
Primary
Concomitant
Neutropenia Other Serious 2/1/2009 54 Female 4/30/2009 Other Health Professional United States
Primary
Secondary
Myalgia Disability 4/14/2009 Female 5/8/2009 Consumer United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 5/6/2009 Female 5/11/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/25/2005 Female 5/13/2009 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 31 Female 5/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 5/6/2009 Female 5/18/2009 Consumer United States
Primary
Concomitant
Skin Haemorrhage Other Serious 59 Female 5/21/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 6/1/2008 Female 5/29/2009 Consumer United States
Primary
Interacting
Malignant Neoplasm Progression Other Serious 8/1/2006 75 Female 6/1/2009 Physician France
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 8/14/2006 75 Female 6/1/2009 Physician France
Primary
Secondary
Concomitant
Lung Infection Life Threatening 8/14/2006 75 Female 6/1/2009 Other Health Professional France
Primary
Secondary
Lung Infection Other Serious 8/14/2006 75 Female 6/5/2009 Physician France
Primary
Secondary
Bone Lesion Other Serious 5/21/2009 Female 6/5/2009 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 52 Female 6/9/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 5/6/2009 Female 160 lb 6/17/2009 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 3/1/2009 42 Female 6/19/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Lung Infection Other Serious 8/14/2006 75 Female 7/1/2009 Physician France
Primary
Secondary
Vomiting Other Serious Female 7/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 8/14/2006 75 Female 7/7/2009 Consumer United Kingdom
Primary
Secondary
Malignant Neoplasm Progression Other Serious 8/1/2006 75 Female 7/9/2009 Physician France
Primary
Secondary
Malignant Neoplasm Progression Other Serious 8/1/2006 75 Female 7/10/2009 Physician France
Primary
Secondary
Respiratory Failure Hospitalization 59 Female 123 lb 7/17/2009 Physician India
Primary
Concomitant
Neutropenia Other Serious 7/30/2009 Consumer United Kingdom
Primary
Secondary
Obstruction Life Threatening 6/21/2009 72 Female 143 lb 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/8/2009 Female 158 lb 8/11/2009 Consumer United States
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 51 Female 8/20/2009 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 60 Female 8/21/2009 Physician United States
Primary
Secondary
Pancreatitis Acute Other Serious 60 Female 8/25/2009 Other Health Professional United States
Primary
Secondary

Drug Data