Carboplatin combined with Cisplatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pleural Effusion Hospitalization 9 Male 12/28/2005 France
Primary
Secondary
Pancytopenia Other Serious 11/15/2004 36 Male 1/10/2006 Consumer United States
Primary
Secondary
Concomitant
Oesophagitis Required Intervention 12/25/2005 Female 172 lb 1/3/2006 United States
Primary
Secondary
Oedema Peripheral Other Serious 67 Male 180 lb 1/4/2006 Pharmacist United States
Primary
Concomitant
Polyneuropathy Other Serious 67 Male 180 lb 1/9/2006 Pharmacist United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 11/15/2004 36 Male 1/24/2006 Consumer United States
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 67 Male 180 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Hydrocephalus Other Serious 1/8/2006 Male 162 lb 2/1/2006 United States
Primary
Secondary
Concomitant
Hydrocephalus Other Serious 1/8/2006 Male 162 lb 2/1/2006 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/15/2005 57 Male 152 lb 2/10/2006 Physician Japan
Primary
Concomitant
Nephritis Interstitial Hospitalization 12/15/2005 57 Male 198 lb 2/17/2006 Austria
Primary
Concomitant
Stomatitis Hospitalization 1/19/2006 55 Male 117 lb 3/10/2006 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 7/15/2005 52 Male 2/1/2006 Other Health Professional United States
Primary
Concomitant
Purpura Hospitalization 12/27/2005 58 Female 3/15/2006 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 36 Male 161 lb 3/16/2006 Japan
Primary
Secondary
Concomitant
Abdominal Pain Upper 52 Female 1/25/2006 United States
Primary
Concomitant
Tongue Disorder Other Serious 5/1/2005 86 Female 104 lb 4/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 8/19/2004 49 Female 4/20/2006 United States
Primary
Concomitant
Rash Hospitalization 12/18/2004 69 Female 84 lb 4/28/2006 Physician Japan
Primary
Concomitant
Rash Generalised Hospitalization 4/1/2006 56 Male 5/10/2006 United States
Primary
Concomitant
Renal Hypertension Hospitalization 2/27/2006 3 Female 29 lb 5/18/2006 Other Health Professional France
Primary
Secondary
Neoplasm Progression Life Threatening 60 Female 5/17/2006 United States
Primary
Secondary
Rash Generalised Hospitalization 4/1/2006 56 Male 5/19/2006 United States
Primary
Concomitant
Peritonitis Bacterial Other Serious Female 5/30/2006 Other Health Professional United Kingdom
Primary
Secondary
Death Death Female 5/30/2006 Other Health Professional United Kingdom
Primary
Secondary
Death Death Female 5/30/2006 Other Health Professional United Kingdom
Primary
Secondary
Rash Hospitalization 12/18/2004 69 Female 84 lb 6/8/2006 Physician Japan
Primary
Concomitant
Neoplasm Recurrence Disability 11/5/2004 72 Male 6/21/2006 Physician Japan
Primary
Secondary
Concomitant
Pharyngeal Fistula Hospitalization 6/12/2006 48 Male 143 lb 6/26/2006 Physician Australia
Primary
Secondary
Concomitant
Pharyngeal Fistula Hospitalization 6/12/2006 48 Male 143 lb 6/30/2006 Physician Australia
Primary
Secondary
Concomitant
Viraemia Hospitalization 6/7/2006 Male 28 lb 6/14/2006 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/2/2006 Female 32 lb 6/14/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/12/2006 Other Health Professional Brazil
Primary
Secondary
Renal Tubular Disorder Hospitalization 2/27/2006 3 Female 29 lb 7/13/2006 Other Health Professional France
Primary
Secondary
Mucosal Inflammation Hospitalization 6/22/2006 74 Female 115 lb 7/28/2006 Other Health Professional United States
Primary
Secondary
Rash Hospitalization 1/12/2006 62 Male 75 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Metastases To Bone Other Serious 47 Female 8/3/2006 Other Health Professional Greece
Primary
Secondary
Pyrexia Hospitalization 47 Female 7/28/2006 Greece
Primary
Secondary
Thrombocythaemia Other Serious 6/1/2006 50 Male 8/4/2006 Physician France
Primary
Concomitant
Thrombocytopenia Hospitalization 7/1/2006 55 Male 165 lb 8/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/2/2005 51 Female 8/30/2006 United Kingdom
Primary
Concomitant
Renal Hypertension Hospitalization 2/27/2006 3 Female 29 lb 9/6/2006 Consumer United States
Primary
Secondary
Renal Hypertension Hospitalization 2/27/2006 3 Female 29 lb 9/7/2006 Other Health Professional France
Primary
Secondary
Renal Failure Acute Hospitalization 2/27/2006 3 Female 29 lb 9/7/2006 Other Health Professional France
Primary
Secondary
Vaginal Infection Other Serious 3/1/2006 Female 133 lb 9/11/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Renal Hypertension Hospitalization 2/27/2006 3 Female 29 lb 9/21/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 62 Male 9/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ovarian Cancer Metastatic Required Intervention 10/1/2003 47 Female 9/20/2006 Greece
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 10/1/2005 9 Male 62 lb 9/28/2006 Consumer France
Primary
Secondary
Concomitant
Trisomy 8 Life Threatening 62 Male 9/21/2006 Physician United States
Primary
Secondary
Haemolytic Anaemia Other Serious 1/1/2006 70 Male 9/18/2006 Other Health Professional United States
Primary
Concomitant
Trisomy 8 Death 62 Male 9/20/2006 Physician United States
Primary
Secondary
Thrombocytopenia Hospitalization 7/7/2006 55 Male 165 lb 9/15/2006 France
Primary
Concomitant
Ovarian Cancer Other Serious 56 Female 10/3/2006 Japan
Primary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 62 Male 10/5/2006 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/27/2006 3 Female 29 lb 10/16/2006 Other Health Professional France
Primary
Secondary
Tachycardia Hospitalization 51 Female 10/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 56 Female 10/25/2006 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 51 Female 10/24/2006 United Kingdom
Primary
Concomitant
Retinopathy Other Serious 60 Male 10/27/2006 Physician France
Primary
Concomitant
Respiratory Failure Life Threatening 7/1/2006 Male 11/9/2006 Physician Belgium
Primary
Secondary
Concomitant
Tongue Disorder Life Threatening 7/1/2006 Male 11/10/2006 Physician Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11 Female 11/1/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/27/2006 3 Female 29 lb 11/17/2006 Consumer United States
Primary
Secondary
Vomiting Hospitalization 1/1/2006 47 Male 11/15/2006 Physician United States
Primary
Concomitant
Stomatitis Necrotising Life Threatening 7/1/2006 Male 11/22/2006 Physician Belgium
Primary
Secondary
Concomitant
Chronic Myelomonocytic Leukaemia Other Serious 1/1/2006 62 Male 11/14/2006 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious Female 11/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Life Threatening 1/1/2006 Male 12/4/2006 Physician Belgium
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 47 Male 140 lb 12/11/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/1/2005 50 Male 11/27/2006 Japan
Primary
Secondary
Spinal Disorder Other Serious 9/18/2006 51 Male 150 lb 12/21/2006 Physician Japan
Primary
Concomitant
Tumour Necrosis Other Serious 1/1/2006 Male 12/22/2006 Physician Belgium
Primary
Secondary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 4/20/2004 47 Female 8/29/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 50 Male 210 lb 1/8/2007 Other Health Professional United States
Primary
Concomitant
Vasculitis Necrotising Other Serious 11/28/2006 71 Female 1/15/2007 Physician Germany
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 4 Female 1/19/2007 Other Health Professional Belgium
Primary
Secondary
Vaginal Infection Other Serious 3/1/2006 Female 133 lb 1/23/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Pancytopenia Other Serious 4 Female 1/19/2007 Physician Belgium
Primary
Secondary
Concomitant
Tenderness Other Serious 4 Female 1/26/2007
Primary
Secondary
Tumour Necrosis Hospitalization 1/1/2006 Male 1/29/2007 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/27/2006 3 Female 29 lb 2/2/2007 Consumer United States
Primary
Secondary
Renal Failure Acute Hospitalization 2/27/2006 3 Female 29 lb 2/2/2007 Consumer United States
Primary
Secondary
Stem Cell Transplant Death 4 Female 1/26/2007 Belgium
Primary
Secondary
Stem Cell Transplant Death 4 Female 2/7/2007 Belgium
Primary
Secondary
Malignant Neoplasm Progression Death 4 Female 2/14/2007 Belgium
Primary
Secondary
Parosmia Disability 1/1/2007 45 Female 2/15/2007 Physician Japan
Primary
Concomitant
Vasculitis Necrotising Other Serious 12/1/2005 60 Male 2/19/2007 Physician United States
Primary
Concomitant
Malignant Neoplasm Progression Death 4 Female 2/26/2007 Belgium
Primary
Secondary
Parosmia 1/1/2007 45 Female 2/22/2007 Physician Japan
Primary
Concomitant
Vasculitis Necrotising Other Serious 11/1/2006 71 Female 3/1/2007 Physician Germany
Primary
Concomitant
Rhabdomyolysis Death Male 3/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Metastasis Death 16 Female 3/5/2007
Primary
Secondary
Azoospermia Other Serious 32 Male 3/8/2007 Other Health Professional Japan
Primary
Secondary
Glioma Other Serious 16 Female 3/8/2007 Consumer Finland
Primary
Secondary
Stem Cell Transplant Death Male 3/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nervous System Disorder Death 16 Female 3/2/2007 Physician Germany
Primary
Secondary
Glioma Other Serious 7 Female 3/9/2007 Consumer Finland
Primary
Secondary
Visual Disturbance Other Serious 49 Female 3/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Malignant Neoplasm Progression Death 4 Female 3/9/2007 Belgium
Primary
Secondary
Blood Luteinising Hormone Increased Other Serious 32 Male 3/6/2007 Japan
Primary
Secondary
Sepsis Hospitalization 2/13/2007 57 Male 142 lb 3/12/2007 Physician China
Primary
Secondary
Treatment Related Secondary Malignancy Death 16 Female 3/1/2007 Germany
Primary
Secondary
Splenomegaly Other Serious 12/1/2006 63 Male 186 lb 3/9/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 53 Female 3/14/2007 Other Health Professional France
Primary
Secondary
Thrombocytopenia Other Serious 53 Female 3/21/2007 Other Health Professional France
Primary
Secondary
Glioma Death 16 Female 3/20/2007 Germany
Primary
Secondary
Thrombocytopenia Death 1/11/2007 Male 3/23/2007 Physician Japan
Primary
Concomitant
Blood Luteinising Hormone Increased Other Serious 32 Male 3/15/2007 Japan
Primary
Secondary
Trisomy 8 Other Serious 62 Male 3/16/2007 United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death Male 4/3/2007 Other Health Professional Japan
Primary
Secondary
Gastrointestinal Haemorrhage Death Male 4/4/2007 Other Health Professional Japan
Primary
Secondary
Pulmonary Haemorrhage Death Male 4/4/2007 Other Health Professional Japan
Primary
Secondary
Gastric Cancer Life Threatening 12/18/2006 Female 4/9/2007 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Life Threatening 12/18/2006 65 Female 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Death 11/24/2006 39 Male 179 lb 4/19/2007 Consumer United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 6/13/2006 58 Male 238 lb 4/17/2007 Physician France
Primary
Concomitant
Hypersensitivity Hospitalization 3/24/2006 Female 4/24/2007 Physician United States
Primary
Secondary
Renal Tubular Disorder Other Serious 4/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 53 Female 4/25/2007 Other Health Professional France
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 1/1/2004 53 Female 5/2/2007 France
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Disability 1/3/2007 64 Male 157 lb 5/21/2007 Physician Japan
Primary
Concomitant
No Adverse Effect 4 Female 5/25/2007 Belgium
Primary
Secondary
Skin Test Positive Other Serious 66 Male 5/14/2007 France
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 66 Male 5/7/2007 France
Primary
Secondary
Concomitant
Memory Impairment Death 20 Male 5/30/2007 Physician Israel
Primary
Secondary
Tooth Extraction Other Serious 12/11/2006 53 Female 6/8/2007 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 12/11/2006 53 Female 6/8/2007 Physician United States
Primary
Concomitant
Urticaria Other Serious 66 Male 5/14/2007 France
Primary
Secondary
Concomitant
Glioblastoma Other Serious 3/1/2005 20 Male 7/5/2007 Other Health Professional Israel
Primary
Secondary
Memory Impairment Death 3/1/2005 20 Male 7/4/2007 Physician Israel
Primary
Secondary
Memory Impairment Death 3/1/2005 20 Male 7/13/2007
Primary
Secondary
Dyspnoea Life Threatening 3/29/2007 62 Female 117 lb 7/16/2007 Physician Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/1/2006 Female 90 lb 7/16/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9 Male 7/17/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 7/26/2007 Physician United States
Primary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 8/2/2007 Physician United States
Primary
Concomitant
Memory Impairment Other Serious 3/1/2005 20 Male 7/27/2007 Israel
Primary
Secondary
Concomitant
Thrombocytopenia 6/20/2007 Female 130 lb 8/6/2007 United States
Primary
Secondary
Pneumonia Other Serious 1/31/2006 66 Female 121 lb 8/10/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 3/1/2005 20 Male 8/14/2007 Consumer United States
Primary
Secondary
Pancytopenia Other Serious 9 Male 8/22/2007 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Pseudomembranous Colitis Other Serious 4/1/2005 9 Male 8/23/2007 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 63 Male 186 lb 7/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 53 NotSpecified 8/24/2007 France
Primary
Secondary
Pancytopenia Hospitalization 9 Male 8/25/2007 Korea, Republic Of
Primary
Secondary
Concomitant
Pseudomembranous Colitis Other Serious 4/1/2005 9 Female 8/22/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Metastases To Central Nervous System Death 3/1/2005 20 Male 8/30/2007 Physician Israel
Primary
Secondary

Drug Data