Carbamazepine combined with Valproic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thoracic Vertebral Fracture Other Serious 1/1/2005 39 Female 1/13/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Traumatic Fracture Other Serious 1/1/2005 38 Male 1/13/2006 Other Health Professional Netherlands
Primary
Secondary
Multiple Congenital Abnormalities Other Serious 1/1/2005 6 Male 1/13/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Synostosis Other Serious 6 Male 1/23/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Urine Calcium Increased Other Serious 38 Male 1/23/2006 Other Health Professional Netherlands
Primary
Secondary
Grand Mal Convulsion Other Serious 38 Male 187 lb 2/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
Completed Suicide Death 36 3/9/2006 United States
Primary
Secondary
Platelet Count Decreased Other Serious 39 Male 3/17/2006 Spain
Primary
Concomitant
Thrombocytopenia Other Serious 2/23/2006 49 Female 3/7/2006 Pharmacist Canada
Primary
Secondary
Thrombocytopenia Other Serious 2/23/2006 49 Female 3/15/2006 Pharmacist Canada
Primary
Secondary
Thrombocytopenia Other Serious 2/23/2006 50 Female 4/7/2006 Pharmacist Canada
Primary
Secondary
Rheumatoid Factor Increased Hospitalization 67 Female 5/9/2006 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Other Serious 2/23/2006 50 Female 5/2/2006 Pharmacist Canada
Primary
Secondary
Syndactyly Congenital Anomaly Female 5/15/2006 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/23/2006 50 Female 5/10/2006 Pharmacist Canada
Primary
Secondary
Subacute Sclerosing Panencephalitis Hospitalization Female 5/26/2006 United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 27 Female 6/20/2006 India
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 30 Female 6/14/2006 Other Health Professional Poland
Primary
Concomitant
Petit Mal Epilepsy Hospitalization 26 Male 6/21/2006 Physician France
Primary
Secondary
Status Epilepticus Hospitalization 17 Male 6/21/2006 Physician France
Primary
Secondary
Grand Mal Convulsion Hospitalization 20 Male 6/28/2006 Physician United States
Primary
Secondary
Status Epilepticus Hospitalization 27 Male 6/28/2006 Physician United States
Primary
Secondary
Lethargy Hospitalization 33 Male 6/28/2006 Physician United States
Primary
Secondary
Lethargy Hospitalization 57 Male 6/28/2006 Physician United States
Primary
Secondary
Somnolence Hospitalization 1/1/1996 10 Female 6/28/2006 Japan
Primary
Secondary
Petit Mal Epilepsy Other Serious 3 Male 6/27/2006 Physician Italy
Primary
Concomitant
Salivary Hypersecretion Other Serious 7 Male 6/27/2006 Physician Italy
Primary
Concomitant
Petit Mal Epilepsy Other Serious 1/1/1994 6 Female 6/27/2006 Physician Italy
Primary
Concomitant
Petit Mal Epilepsy Other Serious 20 Male 6/27/2006 Physician Italy
Primary
Concomitant
Petit Mal Epilepsy Hospitalization 46 Male 6/28/2006 Other Health Professional United States
Primary
Concomitant
Toothache Hospitalization 36 Male 7/31/2006 Spain
Primary
Secondary
Thrombocytopenia Other Serious 2/23/2006 50 Female 8/1/2006 Pharmacist Canada
Primary
Secondary
Somnolence Other Serious 22 Female 8/17/2006 Physician Poland
Primary
Concomitant
Treatment Noncompliance Other Serious 8/5/2004 21 Female 10/4/2006 Physician Colombia
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 63 Female 9/29/2006 United Kingdom
Primary
Secondary
Nephrotic Syndrome Hospitalization Male 10/11/2006 Consumer Spain
Primary
Secondary
Subacute Sclerosing Panencephalitis Hospitalization Female 10/12/2006 United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 9/12/2006 50 Male 179 lb 10/5/2006 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 50 Female 10/10/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization Male 10/10/2006 Spain
Primary
Secondary
Tonsillar Disorder Hospitalization 40 Male 10/13/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 9/12/2006 50 Male 179 lb 10/12/2006 Physician Germany
Primary
Secondary
Drug Toxicity Hospitalization 9/12/2006 Male 10/30/2006 Other Health Professional United States
Primary
Interacting
Drug Toxicity Hospitalization 9/12/2006 50 Male 179 lb 10/30/2006 Physician Germany
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization 9/12/2006 Male 11/16/2006 Other Health Professional United States
Primary
Interacting
Tonsillar Hypertrophy Hospitalization 40 Male 12/19/2006 Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Other Serious 23 Female 1/16/2007 Other Health Professional Chile
Primary
Concomitant
Unevaluable Event Other Serious 11/5/2006 Male 156 lb 2/12/2007 Physician France
Primary
Concomitant
Liver Abscess Other Serious 23 Male 3/5/2007 France
Primary
Concomitant
Status Epilepticus Other Serious 28 Female 3/16/2007 United States
Primary
Concomitant
Interacting
Anticonvulsant Drug Level Below Therapeutic Hospitalization Female 112 lb 3/12/2007 Physician Germany
Primary
Secondary
Status Epilepticus Other Serious 38 Male 4/27/2007 France
Primary
Concomitant
Staring 4/6/2007 44 Male 255 lb 4/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nystagmus Hospitalization 9/12/2006 50 Male 179 lb 5/8/2007 Physician Germany
Primary
Secondary
Concomitant
Thyroid Disorder Hospitalization 63 Female 5/17/2007 United Kingdom
Primary
Secondary
Urinary Tract Infection Hospitalization 23 Female 6/11/2007 Turkey
Primary
Secondary
Concomitant
Pneumonia Hospitalization 42 Male 6/20/2007 United States
Primary
Concomitant
Anxiety Required Intervention 6/19/2007 27 Male 171 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious 16 Male 7/30/2007 United Kingdom
Primary
Secondary
Drug Ineffective Hospitalization 30 Male 8/24/2007 Serbia
Primary
Secondary
Oedema Peripheral Other Serious 16 Male 8/13/2007 United Kingdom
Primary
Secondary
Pyothorax Hospitalization 10 Female 8/30/2007 Japan
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 8/6/2007 Male 112 lb 8/20/2007 Pharmacist United States
Primary
Concomitant
Vitamin B12 Increased Death 1/1/2007 36 Female 135 lb 8/30/2007 Physician United States
Primary
Secondary
Unresponsive To Stimuli Hospitalization 36 Female 135 lb 9/13/2007 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 2/27/2007 Male 139 lb 10/19/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 1/1/2007 36 Female 10/17/2007 Physician United States
Primary
Secondary
Oxygen Saturation Decreased Hospitalization 8/6/2007 42 Male 112 lb 10/24/2007 Pharmacist United States
Primary
Concomitant
Coma Hospitalization 10/25/2007 Female 88 lb 11/6/2007 Physician Romania
Primary
Concomitant
Gastroenteritis Other Serious Male 165 lb 11/7/2007 Physician France
Primary
Concomitant
Mood Swings Other Serious 44 Female 11/16/2007 France
Primary
Concomitant
Coma Hospitalization 10/25/2007 Female 88 lb 11/20/2007 Physician Romania
Primary
Concomitant
Renal Failure Acute Hospitalization 41 Male 11/15/2007 Other Health Professional Japan
Primary
Concomitant
No Therapeutic Response Other Serious 41 Female 11/15/2007 Canada
Primary
Secondary
Spinal Operation Other Serious 2/6/2007 Male 139 lb 11/27/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 41 Female 11/20/2007 Canada
Primary
Secondary
Coma Hospitalization 10/25/2007 Female 88 lb 12/7/2007 Physician Romania
Primary
Concomitant
Spinal Operation Other Serious 2/6/2007 Male 139 lb 12/10/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 18 Female 12/27/2007 Other Health Professional United States
Primary
Secondary
Nuclear Magnetic Resonance Imaging Brain Abnormal Other Serious 40 Male 1/7/2008 United Kingdom
Primary
Concomitant
Gait Disturbance Other Serious 23 Male 2/12/2008 Other Health Professional France
Primary
Secondary
Concomitant
Neurodevelopmental Disorder Disability Male 2/5/2008 Turkey
Primary
Secondary
Gait Disturbance Other Serious 23 Male 2/26/2008 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 4/18/2003 Female 3/19/2008 Germany
Primary
Secondary
Status Epilepticus Hospitalization 1 Male 3/28/2008 Netherlands
Primary
Secondary
Concomitant
Stomach Discomfort 12/1/2006 37 Female 2/15/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2004 27 Female 4/4/2008 Italy
Primary
Secondary
Concomitant
Myxoedema Coma Hospitalization 27 Female 4/14/2008 Italy
Primary
Secondary
Human Herpesvirus 6 Infection Other Serious 34 Male 4/22/2008 Netherlands
Primary
Concomitant
Grand Mal Convulsion Other Serious 3/1/1984 Female 5/30/2008 Physician France
Primary
Secondary
Concomitant
Rash Hospitalization 11/29/2007 Male 6/9/2008 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Other Serious 6/9/2008 34 Male 6/19/2008 Tunisia
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 7/9/2008 Other Health Professional Serbia
Primary
Secondary
Ventricular Septal Defect Congenital Anomaly Male 6 lb 7/8/2008 Physician Mexico
Primary
Secondary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Ventricular Tachycardia Life Threatening 6/26/2008 Female 276 lb 8/12/2008 Physician Netherlands
Primary
Concomitant
Wrong Technique In Drug Usage Process 7/9/2008 29 Male 8/15/2008 United States
Primary
Concomitant
Inhibitory Drug Interaction Hospitalization 23 Male 8/25/2008 Netherlands
Primary
Secondary
Concomitant
Myocardial Infarction Death 75 Male 9/5/2008 United Kingdom
Primary
Secondary
International Normalised Ratio Increased Hospitalization 1 Male 9/3/2008 Physician Netherlands
Primary
Concomitant
Peripheral Coldness Hospitalization 8/1/2004 27 Female 9/24/2008 Other Health Professional Italy
Primary
Concomitant
Osteonecrosis Other Serious 66 Female 10/16/2008 Physician Canada
Primary
Concomitant
Drug Toxicity Other Serious 23 Male 10/28/2008
Primary
Secondary
Epilepsy Disability 1/1/1999 Female 309 lb 11/3/2008 Consumer Netherlands
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Liver Disorder Other Serious 34 Male 11/3/2008 Tunisia
Primary
Concomitant
Drug Interaction Other Serious Female 11/10/2008 Pharmacist France
Primary
Interacting
Thrombocytopenia Other Serious 64 Male 11/21/2008 Portugal
Primary
Concomitant
Interacting
Tic 7/28/2008 64 157 lb 12/9/2008 Consumer United States
Primary
Secondary
Concomitant
Medication Error Death 58 Male 12/23/2008 Physician United States
Primary
Secondary
Medication Error Death 58 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Vomiting Other Serious 11/1/2003 24 Female 1/5/2009 Physician Canada
Primary
Concomitant
Multiple Drug Overdose Accidental Death 58 Male 1/7/2009 United States
Primary
Secondary
Medication Error Death 1/1/2007 58 Male 1/15/2009 Other Health Professional United States
Primary
Secondary
Medication Error Death 58 Male 1/16/2009 United States
Primary
Secondary
Medication Error Death 58 Male 1/16/2009 Physician United States
Primary
Secondary
Accidental Overdose Death 1/27/2009 Other Health Professional United States
Primary
Secondary
Poisoning Death 58 Male 1/21/2009 Physician United States
Primary
Secondary
Accidental Overdose Death 58 Male 1/21/2009 Physician United States
Primary
Secondary
Fibromatosis Other Serious 42 Male 1/28/2009 Switzerland
Primary
Secondary
Death Death 1/1/2007 58 Male 2/3/2009 Pharmacist United States
Primary
Secondary
Suicide Attempt Other Serious Female 3/5/2009 Netherlands
Primary
Secondary
Intra-uterine Death Other Serious Female 3/11/2009 Other Health Professional Netherlands
Primary
Secondary
Suicide Attempt Other Serious Female 3/11/2009 France
Primary
Secondary
Suicide Attempt Life Threatening Female 3/9/2009 Other Health Professional Netherlands
Primary
Secondary
Rouleaux Formation Other Serious 34 Male 3/17/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening Female 3/17/2009 Netherlands
Primary
Secondary
Suicide Attempt Other Serious Female 3/17/2009 Netherlands
Primary
Secondary

Drug Data