Carbamazepine combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Partial Seizures Other Serious 10/15/2005 36 Female 129 lb 1/4/2006 Physician Mexico
Primary
Concomitant
Overdose Hospitalization 23 Female 1/12/2006 Other Health Professional United Kingdom
Primary
Interacting
Vomiting Other Serious 42 Male 1/26/2006 United States
Primary
Secondary
Vomiting Other Serious 17 Female 1/26/2006 United States
Primary
Secondary
Suicidal Ideation Hospitalization 41 Male 2/3/2006 France
Primary
Concomitant
Urinary Tract Infection Hospitalization 72 Female 2/10/2006 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 2/23/2006 Physician United States
Primary
Concomitant
Delirium Other Serious 74 2/25/2006 Japan
Primary
Concomitant
Delirium Other Serious 74 3/3/2006 Japan
Primary
Concomitant
Delirium Other Serious 74 3/3/2006 Japan
Primary
Concomitant
Rash Hospitalization 9/22/2002 15 Male 3/14/2006 Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 3/12/2006 11 Male 3/27/2006 Physician Romania
Primary
Concomitant
Somnolence Other Serious 1/1/1994 32 Female 121 lb 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Other Serious 32 Male 4/6/2006 Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 42 Female 4/10/2006 France
Primary
Secondary
Treatment Noncompliance Hospitalization 1/31/2006 Male 4/10/2006 Physician France
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Other Serious 32 Male 4/12/2006 Japan
Primary
Concomitant
Pancreatitis Other Serious 32 Male 4/19/2006 Physician Spain
Primary
Concomitant
Status Epilepticus Other Serious 17 Male 5/5/2006 Other Health Professional France
Primary
Secondary
Ventricular Fibrillation Death 42 Female 5/3/2006 Other Health Professional Denmark
Primary
Secondary
Vomiting Hospitalization 11/2/2004 52 Female 5/8/2006 Singapore
Primary
Secondary
Concomitant
Caesarean Section Other Serious 23 Female 5/15/2006 France
Primary
Secondary
Neurodevelopmental Disorder Congenital Anomaly 1 Male 5/16/2006 France
Primary
Secondary
Unevaluable Event Required Intervention 23 Female 5/12/2006 Physician Turkey
Primary
Secondary
Neurodevelopmental Disorder Other Serious Male 5/12/2006 Physician Turkey
Primary
Secondary
Aggression Disability 1/6/2005 40 Male 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Hospitalization 2/3/2005 49 Female 5/25/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 2/3/2005 49 Female 121 lb 5/25/2006 Physician United Kingdom
Primary
Concomitant
Chest Pain Other Serious 2/20/2005 52 Female 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Mental Impairment Other Serious 5/2/2006 Male 6/14/2006 Physician Japan
Primary
Secondary
Concomitant
Viiith Nerve Lesion Hospitalization 1/1/2005 Female 6/21/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Interacting
Inappropriate Antidiuretic Hormone Secretion Hospitalization 63 Female 6/22/2006 United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/2/2006 Male 6/23/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/1/2003 39 Female 7/1/2006 Other Health Professional Korea, Republic Of
Primary
Secondary
Grand Mal Convulsion Other Serious 26 Female 6/27/2006 Physician France
Primary
Secondary
Psychiatric Symptom Other Serious 5/2/2006 Male 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization Female 6/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stereotypic Movement Disorder Hospitalization 26 Male 7/6/2006 France
Primary
Secondary
Concomitant
Status Epilepticus Death 2/16/2006 44 Female 7/5/2006 Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 48 Female 86 lb 7/19/2006 Consumer Japan
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious Female 7/13/2006 Korea, Republic Of
Primary
Secondary
Granulocytopenia Required Intervention 9/30/2005 47 Male 1/18/2006 United States
Primary
Concomitant
Pyrexia Hospitalization 10/1/2003 39 Female 7/24/2006 Korea, Democratic People's Republic Of
Primary
Secondary
Tonsillitis Hospitalization 63 Female 8/14/2006 United Kingdom
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 63 Female 8/17/2006 Canada
Primary
Secondary
Concomitant
Hypomania Death 1/1/2003 51 Male 8/8/2006 Finland
Primary
Concomitant
Hepatotoxicity Hospitalization 19 Male 9/1/2006 Australia
Primary
Concomitant
Completed Suicide Death 1/1/2003 51 Male 8/31/2006 Finland
Primary
Concomitant
Face Oedema Other Serious 10/1/2003 39 Female 9/14/2006 Korea, Republic Of
Primary
Concomitant
Peritoneal Fluid Analysis Other Serious 63 Female 9/26/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 15 Female 9/22/2006 Physician Japan
Primary
Concomitant
Weight Decreased Required Intervention 2/27/2006 15 Female 9/28/2006 Physician Japan
Primary
Concomitant
Status Epilepticus Other Serious 26 Male 10/17/2006 Other Health Professional France
Primary
Secondary
Psychomotor Retardation Hospitalization 5/24/2005 67 Male 10/25/2006 Consumer Australia
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 9/10/2006 60 Female 176 lb 11/3/2006 Physician Australia
Primary
Concomitant
Pharyngolaryngeal Pain Hospitalization 40 Male 10/30/2006 Physician Korea, Democratic People's Republic Of
Primary
Concomitant
Surgery Other Serious 10/1/2006 59 Male 12/5/2006 Consumer Hungary
Primary
Concomitant
Mental Impairment Hospitalization 11/7/2006 57 12/19/2006 United Kingdom
Primary
Secondary
Concomitant
Attention Deficit/hyperactivity Disorder Required Intervention 11/1/2006 9 Male 12/4/2006 Physician Japan
Primary
Concomitant
Surgery Other Serious 10/1/2006 59 Male 12/27/2006 Consumer Hungary
Primary
Concomitant
Hepatitis Fulminant Other Serious 10/19/2006 44 Female 1/4/2007 Physician Japan
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 11/23/2006 44 Male 1/11/2007 Other Health Professional France
Primary
Secondary
Vomiting Hospitalization 11/23/2006 44 Male 1/18/2007 Other Health Professional France
Primary
Secondary
Personality Change Required Intervention 11/1/2006 9 Male 1/5/2007 Physician
Primary
Concomitant
Tertiary Sequestrum Other Serious 12/22/2006 53 Female 101 lb 1/25/2007 Physician Singapore
Primary
Concomitant
Pyrexia Other Serious 12/18/2006 2/2/2007 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12/18/2006 Male 150 lb 2/6/2007 Physician Japan
Primary
Concomitant
Polydipsia Death 4/18/2004 Female 220 lb 2/12/2007 Physician Japan
Primary
Concomitant
Tongue Geographic Congenital Anomaly 5/26/2000 Female 57 lb 2/16/2007 Other Health Professional France
Primary
Concomitant
Postpartum Haemorrhage Other Serious 1/1/1982 Female 2/16/2007 Other Health Professional France
Primary
Concomitant
Thirst Death 4/18/2004 Female 220 lb 2/23/2007 Physician Japan
Primary
Concomitant
Tertiary Sequestrum Other Serious 11/1/2006 53 Female 101 lb 2/22/2007 Physician Singapore
Primary
Concomitant
Hepatitis Fulminant Other Serious 10/19/2006 44 Female 3/15/2007 Physician Japan
Primary
Secondary
Concomitant
No Therapeutic Response Hospitalization 7/1/2003 45 Male 3/15/2007
Primary
Secondary
Lymphadenopathy Hospitalization 48 Male 3/12/2007 Physician Spain
Primary
Secondary
Concomitant
Nystagmus Hospitalization 2/25/2007 51 Female 120 lb 3/20/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Mental Disorder Other Serious 3/24/2006 48 Female 128 lb 3/30/2007 France
Primary
Concomitant
Interacting
Nasopharyngitis Other Serious 12/1/2006 Female 4/2/2007 Physician Japan
Primary
Concomitant
Tooth Injury Other Serious 1/1/1978 19 Male 4/13/2007 Australia
Primary
Concomitant
Status Epilepticus Life Threatening 3/21/2007 2 Male 5/10/2007 Other Health Professional France
Primary
Secondary
Tonsillitis Other Serious 63 Female 5/12/2007 United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 30 Female 5/30/2007 Germany
Primary
Concomitant
Tongue Geographic Congenital Anomaly 5/26/2000 Female 57 lb 7/20/2007 Other Health Professional France
Primary
Concomitant
Oedema Peripheral Other Serious 16 Male 8/10/2007 France
Primary
Concomitant
Interacting
Electroencephalogram Abnormal Hospitalization 1/24/2007 11 Female 8/10/2007 Physician Japan
Primary
Concomitant
Electroencephalogram Abnormal Other Serious 1/24/2007 11 Female 8/22/2007 Physician Japan
Primary
Concomitant
Neurological Symptom Other Serious 58 Male 8/27/2007 France
Primary
Secondary
Concomitant
Electroencephalogram Abnormal Other Serious 1/24/2007 11 Female 9/6/2007 Physician Japan
Primary
Concomitant
Electroencephalogram Abnormal Other Serious 74 Male 9/6/2007 Belgium
Primary
Concomitant
Interacting
Small Intestinal Obstruction Other Serious Female 159 lb 9/13/2007 Physician Australia
Primary
Concomitant
Respiratory Tract Infection Hospitalization 11/22/2006 Male 9/23/2007 Physician Japan
Primary
Concomitant
Neurological Symptom Hospitalization 58 Male 9/27/2007 Other Health Professional France
Primary
Secondary
Concomitant
Drug Ineffective Life Threatening 46 Male 10/2/2007 Physician Czech Republic
Primary
Concomitant
Renal Failure Acute Hospitalization 10/1/2005 12/3/2007 Physician Japan
Primary
Concomitant
Dementia Hospitalization Male 12/19/2007 Physician Germany
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 11/16/2006 Female 12/21/2007 Physician Japan
Primary
Concomitant
Petit Mal Epilepsy Other Serious 53 Female 1/10/2008 Other Health Professional France
Primary
Concomitant
Renal Failure Acute Hospitalization 10/1/2005 41 Male 1/16/2008 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 12 Female 1/25/2008 France
Primary
Concomitant
Somatoform Disorder Required Intervention 41 Male 1/17/2008 Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 4/18/2003 Female 2/1/2008 Consumer Germany
Primary
Secondary
Pneumonia Hospitalization 6/11/2007 Female 2/6/2008 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12 Female 2/11/2008 France
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 23 Female 2/13/2008 Other Health Professional Turkey
Primary
Secondary
Interstitial Lung Disease Other Serious 1/16/2008 1 Male 2/7/2008 Physician Japan
Primary
Concomitant
Skin Exfoliation Required Intervention 16 Female 2/13/2008 Tunisia
Primary
Secondary
Osteoporosis Hospitalization 1/27/2008 33 Male 2/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Somnolence Hospitalization 2/11/2008 2 Male 31 lb 3/7/2008 Physician Australia
Primary
Concomitant
Rash Generalised Other Serious 20 Male 3/9/2008 Consumer
Primary
Secondary
Concomitant
Tremor Other Serious 38 Female 3/11/2008 Other Health Professional Australia
Primary
Secondary
Status Epilepticus Life Threatening 11/2/2006 0 Male 15 lb 3/11/2008 Physician Japan
Primary
Concomitant
Tremor Other Serious 38 Female 3/19/2008 Other Health Professional Australia
Primary
Secondary
Somnolence Hospitalization 2/11/2008 2 Male 31 lb 3/19/2008 Physician Australia
Primary
Concomitant
Psychotic Disorder Other Serious 6/24/1994 27 Male 157 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Fall Other Serious 2/13/2008 47 Female 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 4/18/2003 Female 2/13/2008 Other Health Professional Germany
Primary
Secondary
Weight Increased Other Serious 1/1/2008 20 Male 4/9/2008 Consumer United States
Primary
Secondary
Concomitant
Myxoedema Coma Hospitalization 27 Female 4/17/2008 France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/1/2004 27 Female 4/24/2008 Other Health Professional Italy
Primary
Secondary
Social Avoidant Behaviour Death 5/1/1994 27 Male 4/25/2008 Other Health Professional France
Primary
Concomitant
Interacting
Panic Attack Other Serious 22 Female 4/25/2008 Other Health Professional Iran (Islamic Republic Of)
Primary
Secondary
Concomitant
Petit Mal Epilepsy Other Serious 5/1/1995 Female 5/2/2008 Lawyer France
Primary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/20/2007 68 Male 201 lb 5/7/2008 Consumer Ukraine
Primary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myxoedema Coma Hospitalization 27 Female 5/23/2008 France
Primary
Secondary
Concomitant
Vomiting Other Serious 64 Female 5/20/2008 Australia
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Periorbital Oedema Hospitalization 8/1/2004 27 Female 5/23/2008 Physician Netherlands
Primary
Secondary
Grand Mal Convulsion Other Serious 3/1/1984 Female 5/30/2008 Physician France
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Congenital Anomaly 0 Female 21 lb 5/30/2008 India
Primary
Secondary
Feeling Abnormal Other Serious 2/8/2005 57 Male 6/9/2008 United States
Primary
Secondary
Concomitant
Death Death 3/1/2008 Male 6/16/2008 Other Health Professional Germany
Primary
Concomitant
Peripheral Coldness Life Threatening 1/1/2004 27 Female 6/19/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 57 Male 7/3/2008
Primary
Secondary
Concomitant
Weight Increased Other Serious 3 Male 7/14/2008 Netherlands
Primary
Secondary
Concomitant
Weight Increased Other Serious 3 Male 7/14/2008 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 64 Female 7/15/2008 Physician Australia
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6/16/2008 49 Male 7/30/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 6/13/2008 49 Male 168 lb 7/31/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 6/16/2008 49 Male 168 lb 8/12/2008 Physician Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious Female 8/14/2008 Consumer United Kingdom
Primary
Concomitant
Mania Hospitalization 1/10/2008 43 Female 176 lb 8/13/2008 Physician Germany
Primary
Concomitant
Maternal Drugs Affecting Foetus Congenital Anomaly Male 8/18/2008 United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Congenital Anomaly Female 7 lb 8/18/2008 United Kingdom
Primary
Secondary
Myocardial Infarction Death 75 Male 8/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Tetany Other Serious 17 Female 128 lb 8/22/2008 Other Health Professional Turkey
Primary
Secondary
Concomitant
Heart Disease Congenital Congenital Anomaly Male 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Hypospadias Congenital Anomaly Male 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 12/7/2005 28 Female 8/25/2008 Other Health Professional Singapore
Primary
Concomitant

Drug Data