Carbamazepine combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Multiple Congenital Abnormalities Other Serious 1/1/2005 6 Male 1/13/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Synostosis Other Serious 6 Male 1/23/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 56 Female 1/26/2006 France
Primary
Concomitant
Urine Calcium Increased Other Serious 38 Male 1/23/2006 Other Health Professional Netherlands
Primary
Secondary
Completed Suicide Death 40 Male 2/6/2006 Pharmacist United States
Primary
Secondary
Red Blood Cell Abnormality Other Serious 34 Male 3/2/2006 Physician Germany
Primary
Secondary
Metabolic Acidosis Life Threatening 7 Male 29 lb 3/13/2006 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Weight Decreased Death 5/3/2005 49 Male 217 lb 3/16/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious 3/17/2006 56 Male 4/4/2006 Consumer United States
Primary
Secondary
Concomitant
Bladder Cancer Required Intervention 10/1/2005 42 Male 110 lb 4/4/2006 Physician Japan
Primary
Concomitant
Tremor Hospitalization 1/1/2003 34 4/20/2006 United Kingdom
Primary
Secondary
Gait Disturbance Disability 2/1/2006 Female 4/27/2006 Other Health Professional Ireland
Primary
Concomitant
Status Epilepticus Other Serious 17 Male 5/5/2006 Other Health Professional France
Primary
Secondary
Status Epilepticus Other Serious 26 Female 5/8/2006 Other Health Professional France
Primary
Secondary
Transient Ischaemic Attack Other Serious 1/1/2003 Male 209 lb 5/8/2006 Lawyer Canada
Primary
Concomitant
Rheumatoid Factor Increased Hospitalization 67 Female 5/9/2006 Other Health Professional United States
Primary
Secondary
Transient Ischaemic Attack Other Serious 1/1/2002 Male 209 lb 5/10/2006 Lawyer Canada
Primary
Concomitant
Tachycardia Other Serious 3/12/1989 25 Female 5/11/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Metabolic Encephalopathy Other Serious 36 6/12/2006 Japan
Primary
Secondary
Concomitant
Metabolic Encephalopathy Other Serious 36 6/13/2006 Japan
Primary
Secondary
Epilepsy Other Serious 6/9/2006 56 Male 6/20/2006 Consumer Germany
Primary
Interacting
Weight Decreased Death 45 Male 6/19/2006 United States
Primary
Secondary
Status Epilepticus Hospitalization 39 Female 6/21/2006 Physician France
Primary
Secondary
Status Epilepticus Hospitalization 17 Male 6/21/2006 Physician France
Primary
Secondary
Status Epilepticus Hospitalization 26 Female 6/21/2006 Physician France
Primary
Secondary
Concomitant
Weight Decreased Death 45 Male 6/22/2006 Physician United States
Primary
Secondary
Vomiting Hospitalization 21 Male 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 32 Female 6/28/2006 United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 22 Female 6/28/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 48 Female 86 lb 7/19/2006 Consumer Japan
Primary
Concomitant
Overdose Other Serious 12/1/1997 36 Male 7/18/2006 Spain
Primary
Secondary
Concomitant
Vertigo Hospitalization 36 Male 7/24/2006 Pharmacist Spain
Primary
Secondary
Concomitant
Hemiparesis Other Serious 36 Male 8/28/2006 Other Health Professional Spain
Primary
Concomitant
Hepatotoxicity Hospitalization 19 Male 9/1/2006 Australia
Primary
Concomitant
Vertigo Other Serious 36 Male 8/30/2006 Pharmacist Spain
Primary
Secondary
Concomitant
Poor Peripheral Circulation Other Serious 87 Female 9/19/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 37 Male 9/20/2006 Physician Sweden
Primary
Concomitant
Treatment Noncompliance Other Serious 37 Female 9/27/2006 Other Health Professional United States
Primary
Concomitant
Skin Oedema Hospitalization 76 Male 9/21/2006 Physician United Kingdom
Primary
Concomitant
Infusion Site Extravasation Hospitalization 77 Male 165 lb 9/29/2006 Pharmacist Canada
Primary
Concomitant
Stereotypic Movement Disorder Other Serious 39 Female 10/17/2006 Other Health Professional France
Primary
Secondary
Tonsillar Disorder Hospitalization 40 Male 10/13/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Tremor Other Serious 10 Male 10/16/2006 Physician India
Primary
Secondary
Gait Disturbance Other Serious 36 Male 10/27/2006 Canada
Primary
Secondary
Concomitant
Interacting
Vertigo Other Serious 36 Male 10/27/2006 Canada
Primary
Secondary
Concomitant
Interacting
Vomiting Hospitalization 50 Male 10/20/2006 Physician India
Primary
Secondary
Concomitant
Petit Mal Epilepsy Other Serious Male 10/30/2006 Physician Turkey
Primary
Concomitant
Psychotic Disorder Disability 3/1/2006 43 220 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Parkinsonism Other Serious 30 Male 11/10/2006 Physician Turkey
Primary
Concomitant
Tonsillar Hypertrophy Hospitalization 40 Male 12/19/2006 Korea, Republic Of
Primary
Secondary
Concomitant
Hepatitis Other Serious 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Other Serious 12/18/2006 2/2/2007 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 12 Female 2/24/2007 Other Health Professional Turkey
Primary
Concomitant
Epilepsy Other Serious 71 Male 269 lb 3/23/2007 Consumer United Kingdom
Primary
Interacting
Pyroglutamate Increased Hospitalization 50 Male 3/23/2007 Physician India
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 12 Female 3/21/2007 Turkey
Primary
Concomitant
Treatment Noncompliance Hospitalization 12 Female 4/2/2007 Physician Turkey
Primary
Secondary
Tooth Injury Other Serious 1/1/1978 19 Male 4/13/2007 Australia
Primary
Concomitant
Mobility Decreased Other Serious 1/1/2002 53 Female 4/23/2007 Physician United Kingdom
Primary
Concomitant
Multiple Drug Overdose Intentional Death 61 Male 5/8/2007 Physician United States
Primary
Secondary
Urinary Tract Infection Life Threatening 72 Female 5/2/2007 Czech Republic
Primary
Secondary
Vomiting Hospitalization 50 Male 5/8/2007 Other Health Professional India
Primary
Secondary
Concomitant
Immobile Other Serious 1/1/2003 53 Female 5/15/2007 Physician United Kingdom
Primary
Concomitant
Pneumonia Other Serious 3 Female 5/25/2007 Japan
Primary
Concomitant
Interacting
Suicidal Ideation Other Serious 30 Female 5/30/2007 Germany
Primary
Concomitant
Drug Intolerance Other Serious 1/1/2002 60 Male 160 lb 6/4/2007 United States
Primary
Secondary
Transaminases Abnormal Other Serious 62 Male 6/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Other Serious 53 Female 6/23/2007 Consumer Brazil
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 12 Female 6/27/2007 Physician Turkey
Primary
Concomitant
Transaminases Abnormal Life Threatening 62 Male 7/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Drug Ineffective Hospitalization 30 Male 8/24/2007 Serbia
Primary
Secondary
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 62 Male 9/10/2007 United Kingdom
Primary
Secondary
Scratch Other Serious 9/4/2007 Male 9/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 36 Female 135 lb 9/13/2007 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Life Threatening 46 Male 10/2/2007 Physician Czech Republic
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/14/2005 32 Female 9/24/2007 Brazil
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 62 Male 9/28/2007 United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/14/2005 32 Female 10/9/2007 Brazil
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Hospitalization 40 Male 10/10/2007 United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 1/1/2007 36 Female 10/17/2007 Physician United States
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 10/14/2005 32 Female 11/1/2007 Brazil
Primary
Secondary
Concomitant
Rash Hospitalization 10/26/2007 40 Male 11/8/2007 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 24 Male 11/19/2007
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Life Threatening 57 Female 11/16/2007 Physician Japan
Primary
Secondary
Vomiting Hospitalization 10/25/2007 40 Male 11/16/2007 Physician Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms 57 Female 11/21/2007 Physician Japan
Primary
Secondary
Vomiting Hospitalization 10/25/2007 40 Male 11/28/2007 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 18 Female 12/27/2007 Other Health Professional United States
Primary
Secondary
Nuclear Magnetic Resonance Imaging Brain Abnormal Other Serious 40 Male 1/7/2008 United Kingdom
Primary
Concomitant
Petit Mal Epilepsy Other Serious 53 Male 1/10/2008 Other Health Professional France
Primary
Concomitant
Fracture Other Serious 1/1/2007 55 Female 1/28/2008 Physician Japan
Primary
Concomitant
Urosepsis Other Serious 72 Female 2/15/2008 Czech Republic
Primary
Interacting
Leukopenia Other Serious 8/1/1994 67 Male 187 lb 4/22/2008 Physician Germany
Primary
Concomitant
Grand Mal Convulsion Life Threatening 4/8/2008 50 Male 110 lb 5/5/2008 Consumer United Kingdom
Primary
Concomitant
Grand Mal Convulsion Life Threatening 4/8/2008 50 Male 110 lb 5/16/2008 Consumer United Kingdom
Primary
Concomitant
Grand Mal Convulsion Other Serious 3/1/1984 Female 5/30/2008 Physician France
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 34 Female 6/20/2008
Primary
Concomitant
Protein Total Increased Hospitalization 16 Female 7/1/2008 Other Health Professional Japan
Primary
Concomitant
Maternal Drugs Affecting Foetus Congenital Anomaly Male 5 lb 7/9/2008 Physician Mexico
Primary
Secondary
Concomitant
Ventricular Septal Defect Congenital Anomaly Female 7 lb 7/9/2008 Physician Mexico
Primary
Secondary
Concomitant
Ventricular Septal Defect Congenital Anomaly Male 6 lb 7/8/2008 Physician Mexico
Primary
Secondary
Concomitant
Ventricular Septal Defect Congenital Anomaly Female 6 lb 7/8/2008 Physician Mexico
Primary
Secondary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 9 Female 7/4/2008 Italy
Primary
Secondary
Protein Total Decreased Hospitalization 16 Female 7/1/2008 Japan
Primary
Secondary
Concomitant
Ventricular Septal Defect Congenital Anomaly Female 7 lb 7/28/2008 Physician Mexico
Primary
Secondary
Concomitant
Urinary Tract Infection Congenital Anomaly 9 Female 7/24/2008 Italy
Primary
Secondary
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Renal Tubular Necrosis 2/12/2006 23 Female 1/28/2008 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 8/7/2008 25 Female 8/26/2008 Other Health Professional United Kingdom
Primary
Interacting
Death Death 7/2/2008 Female 188 lb 9/2/2008 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 5/14/2008 72 Male 9/3/2008 Pharmacist United States
Primary
Concomitant
Convulsion Hospitalization 8/7/2008 25 Female 8/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Drug Toxicity Hospitalization 66 Male 9/24/2008 Australia
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 50 Female 10/9/2008 Norway
Primary
Secondary
Drug Eruption Other Serious 17 Female 10/9/2008 Norway
Primary
Secondary
Rash Other Serious 53 Male 10/9/2008 Norway
Primary
Secondary
Rash Other Serious 31 Male 10/9/2008 Norway
Primary
Secondary
Visual Impairment Hospitalization 8/27/2008 48 Female 10/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Encephalitis Herpes Hospitalization 9/19/2008 42 Female 132 lb 10/21/2008 Physician Saudi Arabia
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Opportunistic Infection Hospitalization 9/19/2008 42 Female 132 lb 11/3/2008 Physician Saudi Arabia
Primary
Concomitant
Lethargy Hospitalization 9/28/2008 36 Male 9/29/2008 Pharmacist United States
Primary
Concomitant
Strabismus Other Serious 0 Female 8 lb 11/21/2008 United States
Primary
Concomitant
Interacting
Systemic Mycosis Hospitalization 1/1/2008 42 Female 132 lb 12/2/2008 Physician Saudi Arabia
Primary
Concomitant
Weight Decreased Other Serious 12/24/2008 Male 229 lb 12/30/2008 Other Health Professional Japan
Primary
Concomitant
Vomiting Other Serious 11/1/2003 24 Female 1/5/2009 Physician Canada
Primary
Concomitant
Purple Glove Syndrome Life Threatening 11/17/2008 9 1/8/2009
Primary
Concomitant
No Therapeutic Response Hospitalization 38 Female 1/20/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data