Carbamazepine combined with Keppra

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Spina Bifida Death Female 2/25/2006 United Kingdom
Primary
Secondary
Parkinsonism Other Serious 7/1/2005 46 Female 2/20/2006 United Kingdom
Primary
Concomitant
Spina Bifida Other Serious Female 3/8/2006 United Kingdom
Primary
Secondary
Urinary Tract Infection Hospitalization 1/11/2006 65 Female 145 lb 3/9/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/23/2006 49 Female 3/7/2006 Pharmacist Canada
Primary
Secondary
Thrombocytopenia Other Serious 2/23/2006 49 Female 3/15/2006 Pharmacist Canada
Primary
Secondary
Somnolence Other Serious 1/1/1994 32 Female 121 lb 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Eye Swelling Life Threatening 11 71 lb 3/30/2006 United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 2/23/2006 50 Female 4/7/2006 Pharmacist Canada
Primary
Secondary
Thrombocytopenia Other Serious 2/23/2006 50 Female 5/2/2006 Pharmacist Canada
Primary
Secondary
Vomiting Hospitalization 11/2/2004 52 Female 5/8/2006 Singapore
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/23/2006 50 Female 5/10/2006 Pharmacist Canada
Primary
Secondary
Nervousness Other Serious 4/1/2004 43 Female 170 lb 6/7/2006 Physician United Kingdom
Primary
Secondary
Accidental Exposure Other Serious 5/25/2006 36 Female 121 lb 6/8/2006 Germany
Primary
Secondary
Status Epilepticus Death 2/16/2006 44 Female 7/5/2006 Germany
Primary
Concomitant
Lymphopenia Hospitalization 1/1/2006 33 Female 7/12/2006 Other Health Professional Austria
Primary
Concomitant
Periodontitis Other Serious 1/1/2005 41 Female 8/4/2006 Physician Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/23/2006 50 Female 8/1/2006 Pharmacist Canada
Primary
Secondary
Urinary Retention Other Serious 7/27/2006 25 Male 176 lb 8/7/2006 Other Health Professional Germany
Primary
Secondary
Accidental Exposure Other Serious 5/25/2006 36 Female 121 lb 8/10/2006 Germany
Primary
Secondary
Malaise Hospitalization 8/18/2006 64 Male 176 lb 9/7/2006 Physician Australia
Primary
Concomitant
Road Traffic Accident Death 8/26/2006 36 Male 198 lb 9/29/2006 Other Health Professional Canada
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 50 Female 10/10/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization Female 141 lb 11/2/2006 Physician Germany
Primary
Concomitant
Self-medication Life Threatening 4/1/2006 22 Female 276 lb 12/1/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 38 Female 12/7/2006 United States
Primary
Secondary
Concomitant
Delusional Disorder, Persecutory Type Hospitalization 1/1/2002 40 190 lb 12/20/2006 United Kingdom
Primary
Concomitant
Road Traffic Accident Death 8/26/2006 36 Male 198 lb 12/28/2006 Other Health Professional Canada
Primary
Concomitant
Rhabdomyolysis Life Threatening 4/1/2006 22 Female 276 lb 1/8/2007 Physician Germany
Primary
Secondary
Concomitant
Respiratory Depression Hospitalization 12/1/2006 31 Female 2/16/2007 Germany
Primary
Concomitant
Weight Decreased Hospitalization 6/25/2004 39 Female 128 lb 2/22/2007 Physician Germany
Primary
Concomitant
Hip Dysplasia Congenital Anomaly Female 7 lb 3/8/2007 Other Health Professional United Kingdom
Primary
Secondary
Pilonidal Cyst Congenital Congenital Anomaly Male 6 lb 3/9/2007 Consumer United Kingdom
Primary
Secondary
Pilonidal Cyst Congenital Congenital Anomaly Male 6 lb 3/10/2007 United Kingdom
Primary
Secondary
Anticonvulsant Drug Level Below Therapeutic Hospitalization Female 112 lb 3/12/2007 Physician Germany
Primary
Secondary
Suicide Attempt Other Serious 9/16/2004 3/27/2007 Consumer United States
Primary
Concomitant
Leukopenia Hospitalization 1/1/2006 38 Female 3/16/2007 Germany
Primary
Secondary
Epilepsy Other Serious 35 Male 3/14/2007 United Kingdom
Primary
Concomitant
Weight Increased Death 2/1/2004 80 Female 165 lb 3/23/2007 Physician Germany
Primary
Concomitant
Dermatitis Allergic Life Threatening 2/19/2007 58 Male 165 lb 4/24/2007 Physician Belgium
Primary
Concomitant
Multiple Drug Overdose Intentional Death 61 Male 5/8/2007 Physician United States
Primary
Secondary
Respiratory Depression Life Threatening 1/1/2006 31 Female 165 lb 5/1/2007 Germany
Primary
Concomitant
Hallucination Hospitalization 70 Male 5/9/2007 Physician Germany
Primary
Secondary
Status Epilepticus Hospitalization 4/18/2007 53 Male 5/15/2007 Germany
Primary
Concomitant
Hallucination Hospitalization 70 Male 6/4/2007 Physician Germany
Primary
Secondary
Suicide Attempt Other Serious 9/16/2004 6/12/2007 Lawyer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious Female 6/21/2007 Physician United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Other Serious Female 6/21/2007 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious Female 6/26/2007 Physician Germany
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/11/2002 52 Male 7/9/2007 United States
Primary
Concomitant
Psychotic Disorder Other Serious 1/1/2007 46 Male 8/18/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 5/1/2007 26 Female 103 lb 10/8/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/1/2007 26 Female 103 lb 10/19/2007 Consumer United States
Primary
Concomitant
Drug Toxicity Hospitalization 10/12/2007 74 Male 95 lb 11/15/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/1/2007 36 Female 11/9/2007 Physician Germany
Primary
Concomitant
Pyrexia Hospitalization 10/12/2007 74 Male 95 lb 12/3/2007 Physician Korea, Republic Of
Primary
Concomitant
Pyrexia Hospitalization 10/12/2007 74 Male 95 lb 1/14/2008 Physician Korea, Republic Of
Primary
Concomitant
Weight Decreased Other Serious 25 Male 1/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pilonidal Cyst Congenital Congenital Anomaly Male 1/11/2008 United Kingdom
Primary
Secondary
Syncope Other Serious 3 Female 1/22/2008 Spain
Primary
Concomitant
Somnolence Other Serious 2 Male 2/1/2008 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 9/18/2003 46 Male 1/11/2008 United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Required Intervention Female 132 lb 2/19/2008 Physician United States
Primary
Concomitant
Neoplasm Malignant Other Serious Male 2/6/2008 Germany
Primary
Concomitant
Neutropenia Hospitalization 2/1/2008 76 Female 2/15/2008 Germany
Primary
Concomitant
Rectal Haemorrhage Hospitalization Female 2/25/2008 Germany
Primary
Concomitant
Anaemia Hospitalization 1/1/2008 84 Female 181 lb 3/18/2008 Pharmacist Germany
Primary
Concomitant
Weight Decreased Other Serious 5/1/2007 16 Male 143 lb 3/26/2008 Consumer Germany
Primary
Concomitant
Weight Decreased Other Serious 25 Male 4/5/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2007 25 Male 4/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/1/2008 76 Female 4/30/2008 Germany
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/20/2007 68 Male 201 lb 5/7/2008 Consumer Ukraine
Primary
Concomitant
Dysarthria Hospitalization 4/11/2008 51 Male 5/14/2008 Physician Netherlands
Primary
Secondary
Weight Decreased Other Serious 5/1/2007 16 Male 143 lb 5/14/2008 Consumer Germany
Primary
Concomitant
Pregnancy On Oral Contraceptive Other Serious 3/1/2008 22 Female 132 lb 5/16/2008 Physician Germany
Primary
Secondary
Vomiting Hospitalization Male 57 lb 5/27/2008 Physician United Kingdom
Primary
Concomitant
Death Death 3/1/2008 Male 6/16/2008 Other Health Professional Germany
Primary
Concomitant
Weight Decreased Other Serious 5/1/2007 16 Male 143 lb 6/27/2008 Consumer Germany
Primary
Concomitant
Tremor Female 233 lb 7/9/2008 Physician United States
Primary
Concomitant
Convulsion Other Serious Male 7/14/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2007 16 Male 143 lb 7/18/2008 Consumer Germany
Primary
Secondary
Concomitant
Tremor Female 233 lb 7/29/2008 Physician United States
Primary
Concomitant
Hip Dysplasia Other Serious Female 7 lb 8/11/2008 United Kingdom
Primary
Secondary
Diplopia Other Serious 1/1/2008 Male 190 lb 8/18/2008 United States
Primary
Concomitant
Mania Hospitalization 1/10/2008 43 Female 176 lb 8/13/2008 Physician Germany
Primary
Concomitant
Arthralgia Disability 6/1/2008 52 198 lb 8/14/2008 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 9/16/2004 Male 8/20/2008 Lawyer United States
Primary
Concomitant
Somnolence Other Serious 2 Male 24 lb 8/8/2008 Consumer United States
Primary
Concomitant
Diplopia Other Serious 1/1/2008 Male 190 lb 8/29/2008 United States
Primary
Concomitant
Mood Altered Other Serious 4/20/2008 15 Female 132 lb 9/3/2008 Physician Netherlands
Primary
Concomitant
Unresponsive To Stimuli Death 36 Female 9/5/2008 Physician United States
Primary
Secondary
Metastases To Liver Other Serious Male 9/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pregnancy On Contraceptive Other Serious 1/1/2007 22 Female 132 lb 9/12/2008 Physician Germany
Primary
Secondary
Pregnancy On Oral Contraceptive Other Serious 1/1/2008 22 Female 132 lb 9/12/2008 Physician Germany
Primary
Secondary
Urinary Tract Infection Life Threatening 4/1/2008 63 Male 111 lb 10/3/2008 Other Health Professional United Kingdom
Primary
Concomitant
Memory Impairment Other Serious 5/1/2008 40 Male 205 lb 10/2/2008 Consumer Germany
Primary
Secondary
Drug Ineffective Hospitalization 4/1/2008 54 Male 11/5/2008 Germany
Primary
Concomitant
Tooth Loss Other Serious Female 11/13/2008 Physician Germany
Primary
Concomitant
Hepatic Steatosis Life Threatening 10/31/2008 16 Female 12/17/2008 United Kingdom
Primary
Secondary
Neuroblastoma Hospitalization 8/1/2008 2 Female 12/15/2008 Physician Germany
Primary
Secondary
Anticonvulsant Drug Level Increased Hospitalization Male 135 lb 12/24/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 2/23/2009 71 Male 2/23/2009 Physician United States
Primary
Concomitant
Convulsion Other Serious 2/23/2009 71 Male 2/23/2009 Physician United States
Primary
Concomitant
Anticonvulsant Drug Level Increased Hospitalization Male 135 lb 3/13/2009 Consumer United States
Primary
Concomitant
Systolic Hypertension Other Serious 2/23/2009 41 Male 185 lb 3/9/2009 Other Health Professional Germany
Primary
Secondary
Twin Pregnancy Other Serious Female 4/6/2009 Sweden
Primary
Secondary
Osteonecrosis Other Serious 28 Male 4/29/2009 Germany
Primary
Concomitant
Hyperlipidaemia Hospitalization 8/1/2008 44 Male 194 lb 5/7/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 3/1/2005 32 Female 5/20/2009 Physician United Kingdom
Primary
Concomitant
Sleep Disorder Other Serious 3/1/2005 32 Female 5/20/2009 United Kingdom
Primary
Concomitant
Pneumonia Aspiration Hospitalization 3/19/2009 45 Male 6/4/2009 Physician Germany
Primary
Concomitant
Hyponatraemia Death 4/17/2009 63 Female 6/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyponatraemia Death 63 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyponatraemia Death Female 6/23/2009 United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 4/17/2009 63 Female 7/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyponatraemia Death 63 Female 7/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyponatraemia Death 1/1/2008 63 Female 7/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Death 63 Female 7/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyponatraemia Death 4/17/2009 63 Female 7/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyponatraemia Death 63 Female 7/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyperventilation Other Serious 7/15/2009 44 Female 7/29/2009 Consumer Austria
Primary
Concomitant
Hyponatraemia Hospitalization 5/16/2009 39 Male 8/14/2009 United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 8/6/2009 Male 220 lb 8/20/2009 Physician United States
Primary
Concomitant
Electrocardiogram Abnormal Hospitalization 8/6/2009 70 Male 220 lb 8/21/2009 Physician United States
Primary
Concomitant
Hyponatraemia Death 4/15/2009 63 Female 8/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Tonic Convulsion Other Serious Male 8/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 8/6/2009 Male 220 lb 9/2/2009 Physician United States
Primary
Concomitant
Status Epilepticus Other Serious Female 8/28/2009 Consumer United States
Primary
Concomitant
Musculoskeletal Chest Pain Other Serious 8/6/2009 70 Male 220 lb 9/3/2009 Physician United States
Primary
Concomitant
Hyponatraemia Death 4/15/2009 63 Female 9/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyponatraemia Other Serious 4/17/2009 63 Female 9/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Ill-defined Disorder Disability 1/1/2007 64 Male 9/17/2009 France
Primary
Secondary
Concomitant
Off Label Use Other Serious 8/1/2009 33 Female 146 lb 9/28/2009 Pharmacist Germany
Primary
Concomitant
Hyponatraemia Death 63 Female 9/22/2009 United Kingdom
Primary
Concomitant
Hyponatraemia Death 63 Female 9/30/2009 United Kingdom
Primary
Secondary
Dyspnoea Other Serious 75 Male 10/1/2009 Consumer Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 10/21/2009 30 Male 220 lb 11/4/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 50 Female 11/3/2009 Physician United States
Primary
Concomitant
Dyskinesia Other Serious 3/1/2009 13 Male 77 lb 11/5/2009 Physician United Kingdom
Primary
Concomitant
Pregnancy Other Serious 29 Female 11/12/2009 Other Health Professional Germany
Primary
Secondary
Wheezing Other Serious 4/1/2009 63 Female 12/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Dyskinesia Other Serious 3/1/2009 13 Male 77 lb 12/3/2009 Physician United Kingdom
Primary
Concomitant
Systolic Hypertension Other Serious 2/23/2009 Male 185 lb 12/7/2009 Other Health Professional Germany
Primary
Secondary
Suicide Attempt Life Threatening 8/1/2009 Male 122 lb 11/19/2009 United States
Primary
Secondary
Concomitant
Anal Cancer Hospitalization 11/10/2009 Female 216 lb 12/15/2009 Other Health Professional Germany
Primary
Concomitant
Dyspnoea Other Serious 75 Male 12/21/2009 Germany
Primary
Secondary
Concomitant
Dyspnoea Other Serious 75 Male 12/29/2009 Consumer Germany
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/1/2008 44 Male 194 lb 2/3/2010 Pharmacist Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 50 Female 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Lethargy 12/16/2009 27 Female 119 lb 2/24/2010 Other Health Professional United Kingdom
Primary
Secondary

Drug Data