Captopril combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Tachycardia Hospitalization 9/14/2005 57 Female 211 lb 1/12/2006 United States
Primary
Concomitant
Vitamin B Complex Deficiency Hospitalization 6/1/2001 64 Female 351 lb 1/23/2006 Physician United States
Primary
Concomitant
Ventricular Asystole Death 7/15/2004 68 Female 128 lb 2/9/2006 Physician Brazil
Primary
Concomitant
Renal Failure Hospitalization 11/1/2005 62 Male 2/3/2006 Sweden
Primary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Weight Increased Hospitalization 10/1/2003 67 Female 174 lb 3/7/2006 Lawyer United States
Primary
Concomitant
Paraesthesia Other Serious 73 Male 210 lb 3/17/2006 Physician United States
Primary
Secondary
Concomitant
Drug Dispensing Error 8/1/2005 74 Female 249 lb 2/9/2006 United States
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Urinary Tract Infection Fungal Life Threatening 5/19/2005 Male 172 lb 5/9/2006 Physician Portugal
Primary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 1/17/2006 1 Female 5/19/2006 Other Health Professional Ireland
Primary
Concomitant
Rhabdomyolysis 2/19/2006 84 Male 5/24/2006 Switzerland
Primary
Secondary
Concomitant
Chest Pain Hospitalization 10/31/2004 89 Female 6/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Weight Increased Other Serious 76 Female 8/4/2006 Physician United States
Primary
Secondary
Concomitant
Retching 11/1/2005 81 Female 8/10/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 73 Male 8/11/2006 Brazil
Primary
Concomitant
Circulatory Collapse Death 69 Male 9/30/2006 Physician Singapore
Primary
Secondary
Ventricular Arrhythmia Hospitalization 80 Female 10/5/2006 Netherlands
Primary
Secondary
Concomitant
Throat Tightness 11/22/2004 58 Male 11/13/2006 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Death 69 Male 11/14/2006 Physician Singapore
Primary
Concomitant
Sedation Other Serious 1/1/2006 76 Female 175 lb 11/9/2006 United States
Primary
Concomitant
Weight Increased Other Serious 11/5/2006 19 Male 12/7/2006 Japan
Primary
Concomitant
Lupus-like Syndrome Other Serious 49 Male 1/5/2007 Consumer United States
Primary
Secondary
Cerebrovascular Accident Death 72 Female 1/23/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/17/2005 Male 2/2/2007 Pharmacist United States
Primary
Secondary
Respiratory Tract Infection Hospitalization 12/1/2006 36 Female 2/6/2007 Physician Brazil
Primary
Concomitant
Syncope Hospitalization 12/14/2006 80 Male 2/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/9/2004 176 lb 2/23/2007 Physician Germany
Primary
Concomitant
Angioedema 10/7/2006 Female 2/26/2007 Switzerland
Primary
Secondary
Concomitant
Thermal Burn Other Serious 1/1/2006 Male 219 lb 5/22/2007 Consumer United States
Primary
Concomitant
Myalgia 3/7/2007 66 Female 150 lb 6/25/2007 Consumer United States
Primary
Concomitant
Oral Mucosal Blistering 5/1/2007 47 Female 7/6/2007 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Disability 11 Female 4/27/2006 Physician Ireland
Primary
Concomitant
Tachypnoea Other Serious 4/17/2007 6 Female 30 lb 8/7/2007 Physician Netherlands
Primary
Concomitant
Hypotension Hospitalization 7/6/2007 50 Male 9/4/2007 Other Health Professional Philippines
Primary
Secondary
Concomitant
Bronchitis Hospitalization 12/29/2006 1 Male 11/6/2007 Physician Japan
Primary
Concomitant
Influenza Hospitalization 8/17/2007 1 Male 19 lb 11/9/2007 Consumer Brazil
Primary
Concomitant
Bronchitis Hospitalization 12/27/2006 1 Male 11/13/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 1/1/2007 89 Male 11/16/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/1/2007 93 Female 12/27/2007 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/16/2007 0 Male 12/20/2007 Physician Slovenia
Primary
Concomitant
Cardiac Failure Hospitalization 9/28/2006 82 Female 1/29/2008 Physician Italy
Primary
Concomitant
Vertigo Other Serious 10/23/2007 81 Female 2/7/2008 Consumer Poland
Primary
Secondary
Concomitant
Hypotension Other Serious 7/6/2007 Male 4/21/2008 Philippines
Primary
Secondary
Concomitant
Coronary Artery Occlusion Hospitalization 19 Male 5/13/2008 Other Health Professional Brazil
Primary
Secondary
Respiratory Syncytial Virus Infection Life Threatening 1 Female 12 lb 5/9/2008 Other Health Professional Ireland
Primary
Concomitant
Weight Decreased Hospitalization 3/28/2008 82 Male 6/5/2008 United States
Primary
Concomitant
Muscle Rigidity Disability 5/1/2008 1 Female 6 lb 6/27/2008 Physician Australia
Primary
Concomitant
Myocardial Infarction Death 1/22/2008 58 Male 6/28/2008 United States
Primary
Concomitant
Upper Respiratory Tract Infection Death 5/1/2008 1 Female 17 lb 7/30/2008 Physician Australia
Primary
Concomitant
Nausea 1/1/2005 51 Female 319 lb 7/7/2008 Consumer United States
Primary
Concomitant
Post Procedural Swelling Other Serious 5/28/2008 59 Male 196 lb 9/2/2008 United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 6/27/2008 69 Female 9/12/2008 Physician Poland
Primary
Concomitant
Thrombocytopenia Hospitalization 9/27/2008 Male 120 lb 10/3/2008 Ireland
Primary
Concomitant
Pulmonary Artery Stenosis Other Serious 5 Female 10/13/2008
Primary
Secondary
Thrombocytopenia Life Threatening 9/27/2008 Male 120 lb 10/21/2008 Ireland
Primary
Concomitant
Syncope Hospitalization 6/1/2008 87 135 lb 11/25/2008 Consumer United States
Primary
Concomitant
Gastrointestinal Disorder Hospitalization Female 12/17/2008 Brazil
Primary
Concomitant
Drug Interaction Hospitalization 9/29/2008 64 Female 1/5/2009 Consumer Portugal
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2008 Male 153 lb 1/26/2009 Consumer United States
Primary
Concomitant
Death Hospitalization 12/23/2008 Female 12 lb 3/6/2009 Other Health Professional Canada
Primary
Concomitant
Nephrogenic Systemic Fibrosis Disability 1/1/2002 55 Male 190 lb 3/4/2009 Belgium
Primary
Concomitant
Sinus Tachycardia Hospitalization 12/23/2008 Female 12 lb 3/11/2009 Other Health Professional Canada
Primary
Concomitant
Platelet Count Decreased Other Serious Male 178 lb 3/14/2009 Consumer United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 12/23/2008 1 Female 3/3/2009 Canada
Primary
Concomitant
Erythromelalgia Other Serious 3/17/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Tachycardia Hospitalization 12/23/2008 1 Female 3/11/2009 Canada
Primary
Concomitant
Ventricular Fibrillation Other Serious 6/15/2005 3/20/2009 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 60 Female 135 lb 4/3/2009 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 6/1/2004 Male 178 lb 4/22/2009 Consumer United States
Primary
Concomitant
Wheezing Other Serious 2/23/2008 1 Male 5/19/2009 Physician Brazil
Primary
Concomitant
Social Avoidant Behaviour Death Male 5/22/2009 Lawyer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 6/1/2004 Male 178 lb 6/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Generalised Death 2/17/2009 Male 11 lb 6/15/2009 Consumer Brazil
Primary
Concomitant
Wheezing Other Serious 2/23/2008 1 Male 6/11/2009 Physician Brazil
Primary
Concomitant
Wound Infection Death 63 Male 6/26/2009 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 68 Male 179 lb 7/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/12/2009 Portugal
Primary
Concomitant
Heparin-induced Thrombocytopenia Other Serious 5/17/2009 72 Male 8/12/2009 Physician United States
Primary
Secondary
Concomitant
Vocal Cord Paralysis Hospitalization Male 7 lb 8/14/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Death Female 8/18/2009 United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/28/2009 Portugal
Primary
Concomitant
Platelet Production Decreased Other Serious 73 Male 375 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 76 Male 165 lb 8/28/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/21/2007 78 Female 9/11/2009 Lawyer United States
Primary
Concomitant
Wound Infection Hospitalization 63 Male 9/11/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 81 Female 129 lb 9/28/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/21/2007 79 Female 10/22/2009 United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 76 Male 15 lb 10/22/2009 United States
Primary
Concomitant
Psychomotor Retardation Hospitalization 9/12/2009 85 Female 10/28/2009 Other Health Professional Denmark
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/21/2007 79 Female 10/26/2009 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Death 81 Female 10/26/2009 United States
Primary
Concomitant
Stress Other Serious 49 Female 11/4/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/21/2007 79 Female 11/4/2009 Consumer United States
Primary
Concomitant
Tenderness Other Serious 11/20/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Memory Impairment Hospitalization Female 88 lb 11/20/2009 Brazil
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 7/21/2007 79 Female 11/18/2009 United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 81 Female 129 lb 11/17/2009 United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 81 Female 129 lb 12/1/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious Female 12/14/2009 United States
Primary
Concomitant
Memory Impairment Hospitalization Female 88 lb 1/20/2010 Brazil
Primary
Concomitant
Ventricular Fibrillation Life Threatening 81 Female 129 lb 1/11/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Female 1/13/2010 United States
Primary
Concomitant
Respiratory Syncytial Virus Infection Male 1/8/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 73 Female 1/22/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious Female 1/22/2010 United States
Primary
Concomitant
Vomiting Other Serious 49 Female 2/17/2010 United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 5/10/2007 Male 3/12/2010 Physician Brazil
Primary
Concomitant
Peripheral Circulatory Failure Hospitalization 3/1/2010 Female 11 lb 3/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Lung Infection Hospitalization 2/22/2010 Female 190 lb 3/24/2010 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 3/1/2010 Female 3/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Syncytial Virus Infection Hospitalization 1/19/2010 1 Male 22 lb 4/13/2010 Other Health Professional United States
Primary
Concomitant
Cardiomyopathy Other Serious Male 18 lb 4/14/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 67 Female 129 lb 5/14/2010 Lawyer United States
Primary
Concomitant
Upper Airway Obstruction Hospitalization 4/22/2010 Male 15 lb 5/24/2010 Other Health Professional United States
Primary
Concomitant
Faecaloma Hospitalization 10/2/2007 81 Female 123 lb 6/1/2010 Physician Germany
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Hospitalization 5/19/2010 82 Male 147 lb 6/8/2010 Physician United States
Primary
Concomitant
Off Label Use Hospitalization 11/1/2006 61 Female 160 lb 6/22/2010 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Hospitalization 5/19/2010 82 Male 147 lb 6/22/2010 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 5/19/2010 82 Male 147 lb 6/30/2010 Physician United States
Primary
Concomitant
Viith Nerve Paralysis Death 59 Male 7/7/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious Male 18 lb 7/13/2010 Other Health Professional United States
Primary
Concomitant
Ill-defined Disorder Other Serious Male 7/16/2010 Other Health Professional United States
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 59 Male 328 lb 7/21/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Disability 12/1/2002 55 Male 190 lb 7/16/2010 Belgium
Primary
Concomitant
Tremor Other Serious 11/1/2008 64 Female 99 lb 7/23/2010 Consumer Brazil
Primary
Concomitant
Myocardial Infarction Hospitalization 10/14/2002 41 Female 165 lb 7/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Other Serious 5/17/2009 72 Male 5/27/2010 Physician United States
Primary
Secondary
Concomitant
Collapse Of Lung Hospitalization Male 200 lb 8/3/2010 Consumer United States
Primary
Concomitant
Ischaemic Stroke Life Threatening 2/19/2010 51 Male 150 lb 8/4/2010 Physician Brazil
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 2/19/2010 51 Male 150 lb 8/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Completed Suicide Death 6/9/2003 59 Male 8/12/2010 Physician United States
Primary
Concomitant
Ventricular Tachycardia Disability 5/30/2010 0 Female 7 lb 8/16/2010 Physician Brazil
Primary
Concomitant
Ill-defined Disorder Other Serious Male 8/25/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Pruritus Male 280 lb 8/28/2010 Consumer United States
Primary
Concomitant
Influenza Other Serious 5/1/2010 Female 15 lb 9/7/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Disability 5/30/2010 0 Female 7 lb 9/21/2010 Physician Brazil
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 57 Female 10/21/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/29/2010 83 Male 182 lb 10/27/2010 Physician United States
Primary
Concomitant
Influenza Other Serious 5/1/2010 Female 15 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Viral Infection Hospitalization 10/24/2010 Female 11/22/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 65 Female 11/18/2010 Other Health Professional Tunisia
Primary
Secondary
Concomitant
Death Death 12/15/2010 Physician Spain
Primary
Secondary
Concomitant

Drug Data