Capecitabine combined with Trastuzumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lipase Increased Hospitalization 12/17/2005 73 Female 128 lb 3/1/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 12/17/2005 73 Female 128 lb 3/13/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 3/17/2006 50 Male 3/31/2006 Physician Russian Federation
Primary
Secondary
Gout Hospitalization 1/8/2007 71 Male 143 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 100 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 100 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/8/2007 71 Male 143 lb 3/2/2007 Physician Japan
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 11/16/2006 69 Male 170 lb 3/5/2007 Physician Denmark
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/8/2007 71 Male 143 lb 3/6/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/8/2007 71 Male 143 lb 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Rales Hospitalization 3/20/2007 46 Female 90 lb 4/11/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 9/28/2006 Female 115 lb 4/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rales Hospitalization 3/20/2007 46 Female 90 lb 4/17/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Syncope Hospitalization 2/18/2007 Female 196 lb 4/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/18/2007 Female 196 lb 4/25/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rales Hospitalization 3/20/2007 46 Female 90 lb 4/27/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Leukopenia Hospitalization 5/3/2007 55 Female 128 lb 5/18/2007 Physician Austria
Primary
Secondary
Concomitant
Leukopenia Hospitalization 5/3/2007 55 Female 128 lb 5/18/2007 Physician Austria
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/8/2007 71 Male 143 lb 5/22/2007 Physician Japan
Primary
Secondary
Concomitant
Rales Hospitalization 3/20/2007 46 Female 90 lb 6/1/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Cardiovascular Disorder Hospitalization 5/23/2007 75 Female 157 lb 6/27/2007 Physician Germany
Primary
Secondary
Cardiovascular Disorder Hospitalization 5/23/2007 Female 157 lb 6/28/2007 Physician United Kingdom
Primary
Secondary
Chest Pain Hospitalization 12/14/2006 Female 150 lb 6/30/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cervical Myelopathy Hospitalization 6/25/2007 66 Female 110 lb 7/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cervical Myelopathy Hospitalization 6/25/2007 Female 7/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Ischaemia Hospitalization 3/25/2007 51 Female 248 lb 8/17/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/23/2006 37 Female 138 lb 8/24/2007 Physician United States
Primary
Secondary
Vomiting Other Serious 6/27/2007 56 Female 148 lb 8/28/2007 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/31/2006 37 Female 138 lb 9/4/2007 Physician United States
Primary
Secondary
Cerebral Infarction Hospitalization 11/16/2006 69 Male 170 lb 9/19/2007 Physician Denmark
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 11/16/2006 69 Male 170 lb 10/1/2007 Physician Denmark
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/31/2006 36 Female 138 lb 10/5/2007 Physician United States
Primary
Secondary
Acute Monocytic Leukaemia Other Serious 4/11/2007 44 Female 206 lb 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Acute Monocytic Leukaemia Other Serious 4/11/2007 Female 10/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/21/2006 56 Female 168 lb 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 10/21/2007 Male 97 lb 11/20/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/21/2007 Male 97 lb 11/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 10/19/2007 41 Female 11/26/2007 Consumer United Kingdom
Primary
Secondary
Tachycardia Other Serious 6/1/2007 12/6/2007 Physician El Salvador
Primary
Secondary
Neutropenia Other Serious 6/21/2006 56 Female 168 lb 12/7/2007 Physician United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 4/11/2007 44 Female 206 lb 12/31/2007 Physician United States
Primary
Secondary
Concomitant
Gastritis Hospitalization 11/29/2007 Female 121 lb 1/3/2008 Physician United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 4/11/2007 Female 206 lb 1/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy 29 Female 1/10/2008 United States
Primary
Secondary
Ejection Fraction Decreased Hospitalization 12/7/2007 56 Male 120 lb 1/31/2008 Physician Korea, Republic Of
Primary
Secondary
Gastritis Hospitalization 11/29/2007 Female 121 lb 2/1/2008 Consumer United Kingdom
Primary
Secondary
Respiratory Distress Hospitalization 1/6/2008 65 Male 111 lb 2/8/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Gastritis Hospitalization 11/29/2007 26 Female 121 lb 2/8/2008 Physician Mexico
Primary
Secondary
Gastritis Hospitalization 11/29/2007 Female 121 lb 2/14/2008 Consumer United Kingdom
Primary
Secondary
Gastritis Hospitalization 11/29/2007 26 Female 121 lb 2/15/2008 Physician Mexico
Primary
Secondary
Waist Circumference Increased Other Serious 1/1/2004 29 Female 2/15/2008
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 12/7/2007 56 Male 120 lb 2/18/2008 Physician Korea, Republic Of
Primary
Secondary
Cardiac Failure Hospitalization 1/29/2008 69 Male 2/20/2008 Physician Japan
Primary
Secondary
Pyrexia Hospitalization 2/14/2008 64 Male 126 lb 3/4/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 69 Male 104 lb 3/11/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 3/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 69 Male 104 lb 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 3/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/14/2008 64 Male 126 lb 3/19/2008 Physician Japan
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 7/14/2005 Female 3/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 4/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 41 Female 4/15/2008 Other Health Professional Japan
Primary
Secondary
Pain Other Serious 41 Female 4/18/2008 Other Health Professional Japan
Primary
Secondary
Pain 41 Female 4/23/2008 Other Health Professional United States
Primary
Secondary
Malaise Hospitalization 4/7/2008 Male 4/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tetany Hospitalization 4/7/2008 Male 102 lb 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Pain Other Serious 41 Female 4/25/2008 Consumer United States
Primary
Secondary
Pain 41 Female 4/28/2008 Other Health Professional United States
Primary
Secondary
Sepsis Hospitalization 4/7/2008 Male 102 lb 4/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/29/2008 Male 104 lb 5/1/2008 Physician Japan
Primary
Secondary
Concomitant
Death Death 4/7/2007 Male 91 lb 5/1/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 2/4/2008 Male 104 lb 5/6/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 4/7/2007 Male 91 lb 6/4/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Death Death 4/7/2007 Male 91 lb 6/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/14/2008 Male 126 lb 6/10/2008 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 6/12/2008 Physician Japan
Primary
Secondary
Concomitant
Death Death 4/7/2007 Male 91 lb 6/16/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 6/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 3/13/2008 Male 160 lb 6/23/2008 Physician Russian Federation
Primary
Secondary
Concomitant
Death Death 4/7/2007 Male 91 lb 6/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Lethargy Hospitalization 3/20/2008 Male 7/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 7/21/2008 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 7/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiovascular Disorder Hospitalization 5/23/2007 Female 157 lb 8/12/2008 Physician Germany
Primary
Secondary
Cardiovascular Disorder Hospitalization 5/23/2007 Female 157 lb 8/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Lymphoedema Other Serious 3/1/2003 57 Female 9/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Lymphoedema Other Serious 3/1/2003 57 Female 10/6/2008 United Kingdom
Primary
Secondary
Gastrointestinal Haemorrhage Life Threatening 9/19/2008 Male 10/8/2008 Physician United Kingdom
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 69 Female 10/10/2008 Other Health Professional Greece
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 69 Female 10/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 10/2/2008 Male 115 lb 10/15/2008 Physician Korea, Republic Of
Primary
Secondary
Ejection Fraction Decreased Other Serious 3/1/2002 57 Female 10/16/2008 United Kingdom
Primary
Secondary
Concomitant
Death Death 10/2/2008 Male 115 lb 10/17/2008 Consumer United Kingdom
Primary
Secondary
Death Death 10/17/2008 Male 99 lb 10/27/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Death Male 10/27/2008 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 9/12/2008 Male 10/30/2008 Physician United Kingdom
Primary
Concomitant
Death Death 10/17/2008 Male 10/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Chills Hospitalization 11/2/2007 44 Female 11/4/2008 United States
Primary
Secondary
Concomitant
Rash Pustular Hospitalization 9/1/2008 Female 191 lb 11/17/2008 Physician United States
Primary
Secondary
Skin Exfoliation Other Serious 1/1/2008 Female 191 lb 11/20/2008 Physician United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 12/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Ulcer Haemorrhage Hospitalization 46 Female 12/31/2008 Other Health Professional Japan
Primary
Secondary
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 1/5/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 44 Female 1/14/2009 Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 1/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death 12/22/2008 Female 133 lb 1/20/2009 Physician Israel
Primary
Concomitant
Orthostatic Hypotension Hospitalization 5/23/2007 Female 157 lb 1/27/2009 Physician Germany
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 1/1/2008 70 Female 2/13/2009 Consumer United States
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 2/19/2009 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 4/7/2008 Male 102 lb 2/25/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis Other Serious 10/14/2008 Female 180 lb 4/1/2009 Physician United States
Primary
Secondary
Vomiting Other Serious 4/8/2009 Consumer United Kingdom
Primary
Secondary
Thrombosis Other Serious 10/14/2008 Female 180 lb 4/9/2009 Physician United States
Primary
Secondary
Death Death 10/2/2008 Male 115 lb 4/14/2009 Physician Korea, Republic Of
Primary
Secondary
Radiation Myelopathy Other Serious 66 Female 4/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Hospitalization 3/18/2009 Male 4/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 10/2/2008 Male 115 lb 4/20/2009 Consumer United Kingdom
Primary
Secondary
Death Death 4/1/2009 Male 185 lb 4/24/2009 Physician Russian Federation
Primary
Secondary
Thrombosis Other Serious 10/14/2008 Female 180 lb 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Exertional Required Intervention 11/13/2008 47 Female 104 lb 1/5/2009 Pharmacist United States
Primary
Concomitant
Death Death 4/1/2009 Male 185 lb 4/28/2009 Consumer United Kingdom
Primary
Secondary
Vomiting Other Serious Female 4/30/2009 Physician United Kingdom
Primary
Secondary
Metastasis Other Serious 47 Female 5/1/2009 Other Health Professional Netherlands
Primary
Secondary
Visual Impairment Other Serious 31 Female 5/5/2009 Other Health Professional Canada
Primary
Secondary
Metastases To Central Nervous System Other Serious 7/1/2002 38 Female 5/8/2009 Other Health Professional Italy
Primary
Secondary
Small Intestinal Perforation Death 5/12/2009 Consumer United Kingdom
Primary
Secondary
Death Death 4/1/2009 Male 185 lb 5/27/2009 Consumer United Kingdom
Primary
Secondary
Pyrexia Hospitalization 3/18/2009 Male 6/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 63 Female 6/12/2009 Consumer Switzerland
Primary
Secondary
Hypertriglyceridaemia Other Serious 69 Female 6/19/2009 Consumer United Kingdom
Primary
Secondary
Pyrexia Hospitalization 3/18/2009 Male 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 54 Female 7/1/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 54 Female 7/6/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/18/2009 Male 7/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 56 Female 8/3/2009 Other Health Professional Japan
Primary
Secondary
Disease Progression Other Serious 73 8/11/2009 Consumer Switzerland
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 73 8/11/2009 Physician Switzerland
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 31 Female 8/27/2009 Physician Japan
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 55 Female 8/27/2009 Physician Japan
Primary
Secondary
Neutropenia Other Serious 33 Female 8/28/2009 Physician Japan
Primary
Secondary
Malignant Neoplasm Progression Other Serious 64 Female 8/28/2009 Other Health Professional France
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 45 Female 9/4/2009 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 7/20/2009 Female 137 lb 9/9/2009 Physician Japan
Primary
Secondary
Concomitant
Pain Other Serious 37 Female 10/5/2009 Other Health Professional Switzerland
Primary
Secondary
Treatment Failure Other Serious 1/1/2004 27 Female 10/7/2009 Other Health Professional Poland
Primary
Secondary
Pain Other Serious 37 Female 10/8/2009 Other Health Professional Switzerland
Primary
Secondary
Respiratory Failure Death 10/9/2009 Female 165 lb 10/20/2009 Physician Russian Federation
Primary
Secondary
Respiratory Failure Death 10/9/2009 Female 10/22/2009 Physician United Kingdom
Primary
Secondary

Drug Data