Capecitabine combined with Irinotecan

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Oedema Hospitalization 12/16/2005 65 Male 187 lb 1/13/2006 Physician Czech Republic
Primary
Secondary
Sepsis Hospitalization 12/6/2005 61 Female 98 lb 3/30/2006 Other Health Professional United States
Primary
Secondary
Red Blood Cell Count Decreased Hospitalization 3/19/2006 75 Male 146 lb 4/10/2006 Physician Germany
Primary
Secondary
Intestinal Obstruction Hospitalization 3/31/2006 68 Male 137 lb 4/14/2006 Physician Italy
Primary
Secondary
Intestinal Obstruction Hospitalization 3/31/2006 68 Male 137 lb 4/24/2006 Physician Italy
Primary
Secondary
Sepsis Death 6/7/2005 55 Female 132 lb 5/1/2006 Physician Spain
Primary
Secondary
Concomitant
Sepsis Death 6/7/2005 Female 5/2/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/7/2005 55 Female 132 lb 5/16/2006 Physician Spain
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/7/2005 Female 5/18/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/19/2006 75 Male 146 lb 5/31/2006 Physician Germany
Primary
Secondary
Oesophageal Ulcer Hospitalization 3/19/2006 75 Male 146 lb 6/15/2006 Physician Germany
Primary
Secondary
Nausea Hospitalization 5/5/2006 73 Female 107 lb 6/16/2006 Physician United States
Primary
Secondary
Mucosal Inflammation Hospitalization 5/11/2006 70 Female 117 lb 6/23/2006 Physician Germany
Primary
Secondary
Sepsis Hospitalization 4/12/2006 77 Male 6/29/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Lymphangitis Other Serious 6/7/2006 35 Female 11/27/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 12/23/2006 65 Female 3/16/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 12/23/2006 65 Female 3/28/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/4/2005 83 Female 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 12/20/2007 69 Male 148 lb 12/31/2007 Physician Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 1/2/2008 Other Health Professional Italy
Primary
Secondary
Small Intestinal Obstruction Hospitalization 12/20/2007 Male 148 lb 1/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 12/20/2007 69 Male 148 lb 2/1/2008 Physician Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 2/11/2008 Canada
Primary
Secondary
Sepsis Other Serious 2/13/2008 Other Health Professional Canada
Primary
Secondary
Cardiac Failure Hospitalization 1/29/2008 69 Male 2/20/2008 Physician Japan
Primary
Secondary
Upper Gastrointestinal Haemorrhage Hospitalization 10/17/2005 55 Male 2/29/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 69 Male 104 lb 3/11/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 3/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 2/27/2008 72 Male 187 lb 3/12/2008 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/1/2009 67 Male 159 lb 5/13/2010 Physician Spain
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious Female 224 lb 5/18/2010 United States
Primary
Secondary
Concomitant
Perineal Infection Death 9/24/2009 53 Male 163 lb 5/25/2010 Physician France
Primary
Secondary
Perineal Infection Death 9/24/2009 53 Male 6/1/2010 Physician France
Primary
Secondary
Perineal Infection Death 9/24/2009 53 Male 163 lb 6/4/2010 Physician France
Primary
Secondary
Upper Gastrointestinal Haemorrhage Death 5/30/2010 66 Male 187 lb 6/7/2010 Physician Switzerland
Primary
Secondary
Upper Gastrointestinal Haemorrhage Death 5/30/2010 66 Male 187 lb 6/12/2010 Physician Switzerland
Primary
Secondary
Neutropenia Hospitalization 1/15/2010 78 Female 122 lb 6/16/2010 Physician Spain
Primary
Secondary
Intestinal Obstruction Hospitalization 10/26/2003 60 Male 186 lb 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 6/28/2007 51 Female 6/24/2010 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 5/1/2007 50 Female 6/25/2010 Physician United States
Primary
Secondary
Intestinal Obstruction Hospitalization 11/5/2010 67 Male 185 lb 12/1/2010 Physician Spain
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/15/2010 78 Female 122 lb 1/14/2011 Physician Spain
Primary
Secondary
Stomatitis Other Serious 1/19/2011 Other Health Professional Italy
Primary
Secondary
Haematemesis Hospitalization 1/9/2011 72 Male 226 lb 1/20/2011 Physician United States
Primary
Secondary
Concomitant
Neutropenia Death 1/14/2010 58 Male 141 lb 1/25/2011 Physician Spain
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 5/30/2010 66 Male 187 lb 2/16/2011 Physician Switzerland
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 1/14/2010 58 Male 141 lb 3/2/2011 Physician Spain
Primary
Secondary
Concomitant
Cerebrovascular Accident Disability 8/29/2010 56 Female 108 lb 3/10/2011 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/14/2010 58 Male 141 lb 3/11/2011 Physician Spain
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 3/14/2011 Physician Austria
Primary
Secondary
Volvulus Hospitalization 2/1/2011 77 Male 3/14/2011 Consumer United States
Primary
Secondary
Concomitant
Ileus Hospitalization 5/13/2007 64 Female 128 lb 3/15/2011 Physician Germany
Primary
Secondary
Concomitant
Intestinal Obstruction Death 3/15/2011 71 Female 129 lb 3/25/2011 Physician Spain
Primary
Secondary
Concomitant
Intestinal Obstruction Death 3/15/2011 71 Female 129 lb 3/29/2011 Physician Spain
Primary
Secondary
Concomitant
Meningitis Bacterial Death 2/16/2011 73 Male 225 lb 3/30/2011 Physician Spain
Primary
Secondary
Concomitant
Fall Hospitalization 3/12/2011 71 Male 159 lb 4/12/2011 Physician Canada
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/17/2011 71 Male 159 lb 4/14/2011 Physician Canada
Primary
Secondary
Concomitant
Rash Life Threatening 9/18/2010 50 Male 225 lb 10/9/2013 Physician De
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 6/18/2011 74 Female 105 lb 7/25/2013 Physician De
Primary
Secondary
Concomitant
Vomiting Other Serious NotSpecified 12/20/2013 Other Health Professional Fr
Primary
Secondary
Neuropathy Peripheral Other Serious NotSpecified 1/21/2013 Physician Cn
Primary
Secondary
Concomitant
Vomiting Other Serious NotSpecified 8/7/2013 Other Health Professional Kr
Primary
Secondary
Pyrexia Hospitalization 8/6/2012 61 Female 135 lb 10/26/2012 Other Health Professional Us
Primary
Concomitant
Disease Progression Other Serious 8/7/2012 44 Female 99 lb 10/23/2013 Physician Ru
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization Female 9/27/2012 Physician Us
Primary
Secondary
Concomitant
Sepsis Death 57 Male 10/5/2012 Country Not Specified
Primary
Secondary
Paraesthesia Other Serious 8/27/2008 63 Male 174 lb 10/15/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Disease Progression Other Serious 65 Female 176 lb 10/18/2012 Physician Br
Primary
Secondary
Concomitant
Disease Progression Other Serious 60 Female 108 lb 11/8/2012 Physician Br
Primary
Secondary
Concomitant
Disease Progression Other Serious 66 Male 150 lb 10/19/2012 Physician Br
Primary
Secondary
Disease Progression Other Serious 40 Male 165 lb 11/8/2012 Physician Br
Primary
Secondary
Paraesthesia Other Serious 10/8/2008 63 Male 174 lb 10/18/2012 Gb
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/15/2012 59 Male 306 lb 10/24/2012 Pharmacist Us
Secondary
Concomitant
Paronychia Death 13 Female 4/23/2013 Other Health Professional Rs
Primary
Concomitant
Paraesthesia Other Serious 9/12/2007 71 Male 10/23/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Disease Progression Other Serious Male 157 lb 10/31/2012 Physician Br
Primary
Secondary
Disease Progression Other Serious 64 Female 157 lb 11/1/2012 Physician Br
Primary
Secondary
Disease Progression Other Serious 66 Female 115 lb 11/1/2012 Physician Br
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/17/2012 Physician Country Not Specified
Primary
Secondary
Pancreatitis Hospitalization 9/29/2012 42 Female 11/9/2012 Physician Ca
Primary
Secondary
Concomitant
Death Death 7/19/2009 60 Male 11/23/2012 Physician Us
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 9/5/2012 58 Female 185 lb 12/31/2012 Physician Ru
Primary
Secondary
Concomitant
Pulmonary Artery Thrombosis Other Serious 7/19/2012 42 Male 187 lb 12/11/2012 Physician Si
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/2010 54 Female 12/3/2012 Jp
Primary
Secondary
Concomitant
Sinusitis Hospitalization 5/7/2010 66 Male 187 lb 12/24/2012 Physician Fi
Primary
Secondary
Disease Progression Other Serious 11/26/2012 60 Female 170 lb 12/24/2012 Physician Ru
Primary
Secondary
Concomitant
Gangrene Hospitalization 6/21/2010 67 Male 12/24/2012 Physician Si
Primary
Secondary
Concomitant
Proctitis Other Serious 12/26/2012 Physician Country Not Specified
Primary
Secondary
Pyrexia Hospitalization 11/7/2012 58 Female 99 lb 12/28/2012 Physician Hu
Primary
Secondary
Pulmonary Embolism Disability 5/28/2012 74 Female 112 lb 1/3/2013 Physician De
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2009 73 Male 161 lb 1/7/2013 Physician Gb
Primary
Secondary
Concomitant
Cerebral Ischaemia Hospitalization 12/4/2011 58 Male 7/2/2013 Physician Hu
Primary
Secondary
Weight Decreased Hospitalization 2009 73 Male 161 lb 1/9/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 12/6/2006 45 Female 162 lb 1/9/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Subileus Hospitalization 9/18/2012 67 Male 1/9/2013 Physician Hu
Primary
Secondary
Weight Decreased Hospitalization 2009 73 Male 161 lb 1/15/2013 Physician Gb
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 2009 65 Male 160 lb 1/16/2013 Physician Gb
Primary
Secondary
Pancreatic Carcinoma Hospitalization Female 112 lb 1/22/2013 Physician Fr
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 69 Male 1/22/2013 Physician Fi
Primary
Secondary
Concomitant
Vomiting Other Serious NotSpecified 2/4/2013 Other Health Professional Country Not Specified
Primary
Secondary
Weight Decreased Hospitalization 73 Male 161 lb 1/16/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2009 73 Male 1/18/2013 Physician Dk
Primary
Secondary
Concomitant
Proctitis Other Serious NotSpecified 1/14/2013 Physician Country Not Specified
Primary
Secondary
Tumour Marker Increased Other Serious 5/2013 66 Female 134 lb 9/5/2013 Physician Au
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious NotSpecified 5/24/2013 Other Health Professional Country Not Specified
Primary
Secondary
Vomiting Other Serious NotSpecified 3/9/2013 Other Health Professional Country Not Specified
Primary
Secondary
Vomiting Other Serious NotSpecified 3/11/2013 Other Health Professional Country Not Specified
Primary
Secondary
Angina Unstable Life Threatening 3/7/2012 72 Female 3/12/2013 Physician Ca
Primary
Secondary
Thrombosis Other Serious NotSpecified 3/21/2013 Other Health Professional Country Not Specified
Primary
Secondary
Neoplasm Progression Hospitalization 1/4/2013 65 Male 172 lb 3/26/2013 Physician De
Primary
Secondary
Vomiting Other Serious NotSpecified 3/26/2013 Other Health Professional Country Not Specified
Primary
Secondary
Myocardial Infarction Death NotSpecified 3/27/2013 Other Health Professional Ca
Primary
Secondary
Colitis Death NotSpecified 3/27/2013 Other Health Professional Ca
Primary
Secondary
Vomiting Death NotSpecified 4/3/2013 Other Health Professional Country Not Specified
Primary
Secondary
Wound Dehiscence Other Serious NotSpecified 4/8/2013 Other Health Professional Country Not Specified
Primary
Secondary
Large Intestine Perforation Life Threatening 4/3/2013 62 Male 5/3/2013 Physician At
Primary
Secondary
Concomitant
Ureteral Disorder Hospitalization 4/16/2013 54 Male 141 lb 5/15/2013 Physician Cn
Primary
Secondary
Concomitant
Ischaemia Other Serious 70 Male 5/10/2013 Physician Dz
Primary
Secondary
Lower Gastrointestinal Haemorrhage Hospitalization 4/19/2013 68 NotSpecified 209 lb 5/24/2013 Physician De
Primary
Concomitant
Renal Failure Hospitalization 5/7/2013 NotSpecified 5/20/2013 Physician At
Primary
Secondary
Female Genital Tract Fistula Other Serious 2/2013 44 Female 190 lb 7/16/2013 Physician De
Primary
Secondary
White Blood Cell Disorder Other Serious NotSpecified 7/15/2013 Other Health Professional Cn
Primary
Secondary
Sepsis Death 5/27/2013 NotSpecified 6/6/2013 Physician At
Primary
Secondary
Periportal Sinus Dilatation Other Serious NotSpecified 6/10/2013 Physician It
Primary
Secondary
Vomiting Other Serious NotSpecified 7/5/2013 Other Health Professional Tr
Primary
Secondary
Vomiting Other Serious NotSpecified 6/26/2013 Other Health Professional Cn
Primary
Secondary
Renal Failure Hospitalization 6/20/2013 66 Female 174 lb 9/28/2013 Physician De
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 6/11/2013 73 Male 8/2/2013 Physician De
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 61 Male 7/22/2013 Physician Cn
Primary
Concomitant
Metabolic Encephalopathy Hospitalization NotSpecified 8/9/2013 Physician Us
Primary
Secondary
Xerosis Other Serious NotSpecified 8/12/2013 Other Health Professional Ru
Primary
Concomitant
Pelvic Mass Other Serious 12/2012 41 Female 8/20/2013 Physician Au
Primary
Secondary
Concomitant
Rectal Cancer Recurrent Other Serious 8/2012 35 Female 8/16/2013 Other Health Professional Si
Primary
Secondary
Concomitant
Vomiting Other Serious 37 Male 8/22/2013 Other Health Professional Fr
Primary
Secondary
Polyneuropathy Other Serious 50 Female 9/4/2013 Other Health Professional De
Primary
Secondary
Concomitant
Vomiting Other Serious NotSpecified 9/10/2013 Other Health Professional Ru
Primary
Secondary
Intestinal Perforation Death 7/12/2013 50 Male 132 lb 9/28/2013 Physician Cn
Primary
Secondary
Disease Progression Other Serious 2/2013 69 Male 9/11/2013 Physician Au
Primary
Concomitant
Vomiting Other Serious 37 Male 9/12/2013 Other Health Professional Fr
Primary
Secondary
Urinary Tract Infection Hospitalization 11/25/2009 50 Female 143 lb 9/19/2013 Physician De
Primary
Concomitant
Proteinuria Other Serious NotSpecified 10/8/2013 Physician Ro
Primary
Secondary
General Physical Health Deterioration Hospitalization 7/15/2013 NotSpecified 10/18/2013 Physician At
Primary
Secondary
Thrombocytopenia Other Serious NotSpecified 10/22/2013 Other Health Professional Us
Primary
Secondary
Bacterial Test Positive Other Serious NotSpecified 10/28/2013 Physician Gb
Primary
Secondary
Metastases To Liver Other Serious 73 NotSpecified 10/30/2013 Physician Gb
Primary
Secondary
Concomitant
Wound Complication Other Serious NotSpecified 12/5/2013 Physician Gb
Primary
Secondary
Bacterial Test Positive Hospitalization 10/23/2013 27 Male 190 lb 11/1/2013 Physician Us
Primary
Secondary
Blood Culture Positive Other Serious NotSpecified 11/22/2013 Other Health Professional Gb
Primary
Secondary
White Blood Cell Count Increased Other Serious 10/18/2013 59 Male 11/20/2013 Physician Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious NotSpecified 11/20/2013 Physician Gb
Primary
Secondary

Drug Data