Capecitabine combined with Herceptin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Extraction Disability 1/1/2005 Female 3/17/2006 Physician Australia
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 8/23/2005 42 Female 154 lb 4/3/2006 Consumer Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/16/2006 49 Female 174 lb 6/20/2006 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/21/2006 56 Female 168 lb 7/21/2006 Physician United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 7/18/2005 46 Female 7/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2006 63 Female 212 lb 8/2/2006 Physician Germany
Primary
Secondary
Concomitant
Haematemesis Hospitalization 7/17/2006 58 Female 207 lb 8/7/2006 Physician Germany
Primary
Secondary
Neutropenia Other Serious 6/21/2006 56 Female 168 lb 8/11/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/8/2006 63 Female 212 lb 8/14/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/16/2006 49 Female 174 lb 8/16/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/31/2006 51 Male 101 lb 10/2/2006 Physician China
Primary
Secondary
Gastric Perforation Life Threatening 9/21/2006 52 Male 188 lb 10/4/2006 Physician Korea, Republic Of
Primary
Secondary
Gastric Perforation Life Threatening 9/21/2006 52 Male 188 lb 10/23/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/18/2006 54 Female 100 lb 11/13/2006 Physician Japan
Primary
Secondary
Vomiting Hospitalization 10/22/2006 54 Female 100 lb 11/21/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 77 lb 1/5/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/24/2006 64 Female 163 lb 2/21/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 11/24/2006 64 Female 163 lb 2/21/2007 Physician United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 Female 4/6/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 3/20/2007 Female 4/6/2007 Pharmacist United Kingdom
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious Female 4/6/2007 Pharmacist United Kingdom
Primary
Secondary
Tachycardia Other Serious 6/1/2006 Female 4/30/2007 Physician Panama
Primary
Secondary
Skin Fissures Other Serious Female 138 lb 5/7/2007 Pharmacist United Kingdom
Primary
Secondary
Tooth Extraction Disability 1/1/2005 Female 5/30/2007 Physician Australia
Primary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 Female 6/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 3/20/2007 Female 7/3/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Skin Fissures Other Serious Female 138 lb 7/19/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 58 Female 2/12/2008 Consumer United Kingdom
Primary
Secondary
Mucosal Inflammation Hospitalization 1/25/2008 79 Female 3/3/2008 Italy
Primary
Concomitant
Thrombocytopenia Other Serious 9/3/2005 57 Female 185 lb 4/2/2008 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 5/10/2008 85 Female 163 lb 7/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 5/10/2008 85 Female 7/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Tamponade Other Serious Female 7/17/2008 Consumer Japan
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 1/1/2008 25 Female 8/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 4/8/1999 65 Female 152 lb 12/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 12/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 1/5/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 1/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 12/1/2006 55 Female 3/17/2009 Consumer Finland
Primary
Secondary
Anaemia Life Threatening 11/6/2008 77 Female 3/25/2009 Physician France
Primary
Secondary
Concomitant
Thrombosis Other Serious 10/14/2008 Female 180 lb 3/27/2009 Physician United States
Primary
Concomitant
Thrombosis Other Serious 10/14/2008 Female 4/7/2009 Physician United Kingdom
Primary
Secondary
Thrombosis Other Serious 10/14/2008 Female 4/14/2009 Physician United Kingdom
Primary
Secondary
Radiation Myelopathy Other Serious 6/1/2007 66 Female 4/21/2009 Consumer United Kingdom
Primary
Secondary
Thrombosis Other Serious 10/14/2008 Female 5/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 31 Female 5/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 1/1/2008 36 Female 5/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 7/1/2002 38 Female 5/18/2009 Consumer United Kingdom
Primary
Secondary
Vomiting Other Serious Female 5/19/2009 United Kingdom
Primary
Secondary
Metastases To Liver Other Serious 36 Female 5/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Stomatitis Other Serious 5/29/2009 Physician Greece
Primary
Secondary
Concomitant
Skin Ulcer Haemorrhage Other Serious 2/27/2009 6/9/2009 Consumer United Kingdom
Primary
Secondary
Stomatitis Other Serious 6/12/2009 Physician Greece
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious Female 6/18/2009 Consumer United Kingdom
Primary
Secondary
Vomiting Other Serious Female 7/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 7/15/2009 Physician United Kingdom
Primary
Secondary
Death Death 7/8/2009 Female 7/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Female 7/23/2009 Consumer United States
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 56 Female 8/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Breast Cancer Metastatic Life Threatening 7/28/2009 Female 168 lb 8/19/2009 Physician Canada
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 55 Female 9/1/2009 Physician United Kingdom
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 54 Female 9/1/2009 Physician United Kingdom
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 60 Female 9/1/2009 Physician United Kingdom
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 31 Female 9/1/2009 Physician United Kingdom
Primary
Secondary
Oedema Peripheral Other Serious 55 Female 9/3/2009 Physician United Kingdom
Primary
Secondary
Neutropenia Other Serious 33 Female 9/3/2009 Physician United Kingdom
Primary
Secondary
Treatment Failure Other Serious 1/1/2007 27 Female 10/9/2009 Consumer United Kingdom
Primary
Secondary
Metastases To Eye Other Serious 37 Female 10/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Cardiac Failure Acute Death 7/8/2009 Female 10/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 7/8/2009 Female 10/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 7/8/2009 Female 10/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2008 Female 195 lb 10/26/2009 Physician United States
Primary
Secondary
Concomitant
Treatment Failure Other Serious 1/1/2007 29 Female 10/28/2009 Consumer United Kingdom
Primary
Secondary
Salpingo-oophoritis Other Serious 1/1/2007 29 Female 11/11/2009 Consumer United Kingdom
Primary
Secondary
Vomiting Other Serious 11/28/2008 Female 12/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 7/8/2009 Female 12/3/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 7/8/2009 Female 12/3/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Myelitis Transverse Disability 6/1/2009 Female 193 lb 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 4/16/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 4/20/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 5/10/2010 United States
Primary
Concomitant
Rash Hospitalization 2/3/2010 73 Female 5/11/2010 Physician Romania
Primary
Concomitant
Fall Hospitalization 4/1/2010 57 Female 232 lb 5/21/2010 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 9/1/2006 44 Female 6/1/2010 Physician Poland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/15/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/17/2010 United States
Primary
Concomitant
Effusion Hospitalization 4/1/2010 63 Female 123 lb 8/27/2010 Consumer United States
Primary
Concomitant
Dermatitis Exfoliative Hospitalization 10/18/2010 Female 10/25/2010 Physician Argentina
Primary
Concomitant
Sensory Loss Death 49 Female 12/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sensory Loss Death 10/1/2010 49 Female 12/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Lower Limb Fracture Hospitalization 2/28/2011 80 Female 125 lb 3/18/2011 Consumer United States
Primary
Concomitant
Metastases To Meninges Other Serious 1/1/2004 3/25/2011 Physician United States
Primary
Concomitant
Hypokalaemia Other Serious 3/15/2011 44 Female 198 lb 4/7/2011 Consumer United Kingdom
Primary
Concomitant
Hypersensitivity Other Serious 10/1/2010 38 Female 4/25/2011 Consumer United States
Primary
Secondary
Palmar Erythema Hospitalization 4/18/2011 52 Male 141 lb 5/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Disability 3/30/2011 51 Female 5/11/2011 Consumer Panama
Primary
Secondary
Blood Sodium Decreased Hospitalization 4/30/2011 51 Female 5/13/2011 Consumer Panama
Primary
Secondary
Disease Progression Death 10/1/2010 49 Female 6/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Urticaria Hospitalization 11/2/2010 49 Female 119 lb 1/13/2012 Consumer Mexico
Primary
Concomitant
Surgery Congenital Anomaly 30 1/19/2012 Physician Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Death 1/30/2012 49 Female 2/23/2012 Consumer Guatemala
Primary
Concomitant
Joint Swelling Hospitalization 3/1/2011 Female 4/23/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Dry Skin Other Serious 12/1/2011 65 Female 5/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Dizziness Hospitalization 3/1/2011 Female 5/8/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Confusional State Hospitalization 9/21/2011 Female 5/3/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Chapped Death 1/1/2011 44 Female 5/9/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Death 3/1/2011 Female 5/10/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Pustular Hospitalization 3/1/2011 Female 5/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Disorder Death 2/26/2011 Female 5/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gait Disturbance Life Threatening 3/1/2011 Female 5/11/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Toxicity Death 3/1/2011 Female 5/14/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Dry Skin Other Serious 12/1/2011 65 Female 5/14/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 3/11/2012 Female 5/10/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Rash Pustular Death 3/1/2011 Female 5/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophilia Death 2/26/2011 43 Female 174 lb 5/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Pustular Death 1/1/2011 45 Female 5/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Disease Progression Other Serious 65 Female 5/17/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Erythema Hospitalization 3/1/2011 45 Female 5/18/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ingrowing Nail Hospitalization 1/1/2011 45 Female 5/18/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12/1/2011 65 Female 5/23/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Pustular Death 1/1/2011 45 Female 5/24/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Balance Disorder Hospitalization 9/21/2011 43 Female 174 lb 5/15/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 1/1/2011 45 Female 5/15/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 11/11/2011 51 Female 348 lb 6/3/2012 Physician United Kingdom
Primary
Concomitant
Pulmonary Artery Thrombosis Other Serious 55 Male 6/8/2012 Other Health Professional Japan
Primary
Secondary
Neutropenic Sepsis Death 11/11/2011 51 Female 158 lb 6/5/2012 Other Health Professional United Kingdom
Primary
Concomitant
Metastases To Liver Other Serious 59 Female 6/29/2012 Physician Japan
Primary
Concomitant
Metastases To Lung Other Serious 59 Female 7/5/2012 Japan
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 5/21/2012 60 Female 154 lb 7/11/2012 Physician United States
Primary
Concomitant
Disease Recurrence Other Serious 1/1/2006 45 Female 8/3/2012 Physician Australia
Primary
Secondary
Concomitant
Metastases To Lung Other Serious 4/16/2009 59 Female 8/15/2012 Physician Japan
Primary
Concomitant
Pulmonary Artery Thrombosis Hospitalization 55 Male 11/7/2012 Consumer Jp
Primary
Secondary
Pain In Extremity Other Serious Female 10/1/2012 Physician Us
Primary
Secondary
Concomitant
Neoplasm Malignant Death Male 148 lb 10/22/2012 Physician Au
Primary
Secondary
Haematuria Other Serious 11/3/2012 72 Male 11/14/2012 Physician Ve
Primary
Secondary
Concomitant
Disease Progression Other Serious 12/2011 38 Female 12/17/2012 Country Not Specified
Primary
Concomitant
Disease Progression Other Serious Female 1/8/2013 Physician Au
Primary
Secondary
Concomitant
Renal Function Test Abnormal Other Serious 58 Female 1/25/2013 Physician Pl
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 206 lb 2/28/2013 Pharmacist Ie
Primary
Concomitant
Disease Progression Other Serious 3/2008 44 Female 3/7/2013 Physician At
Primary
Secondary
Concomitant
Metastatic Neoplasm Other Serious 2/2011 36 Female 6/17/2013 Physician Au
Primary
Secondary
Concomitant
Somnolence Other Serious 1/30/2013 61 Female 168 lb 3/18/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Nausea Other Serious 12/28/2012 Female 3/25/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Vasculitis Cerebral Hospitalization 5/2012 47 Female 3/11/2013 Physician Pt
Primary
Concomitant
Somnolence Other Serious 1/30/2013 61 Female 168 lb 3/26/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Disease Progression Other Serious NotSpecified 4/18/2013 Physician Au
Primary
Secondary
Concomitant
Metastases To Liver Death 9/2011 Female 5/2/2013 Consumer Gb
Primary
Concomitant
Renal Failure Other Serious 2013 Female 6/6/2013 Consumer Gb
Primary
Secondary
Concomitant
Death Death 41 Female 128 lb 6/7/2013 Physician Mx
Primary
Concomitant
Vomiting Life Threatening 58 Female 6/27/2013 Consumer Au
Primary
Secondary
Concomitant

Drug Data