Candesartan Cilexetil combined with Loxonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Hospitalization 10/13/2005 Male 1/20/2006 Physician Japan
Primary
Concomitant
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 3/15/2006 Physician Japan
Primary
Concomitant
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 4/11/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/13/2007 68 Female 141 lb 7/23/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 52 Male 8/7/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/10/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 3/13/2007 52 Male 8/14/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/16/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 52 Male 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
Restlessness Disability 7/31/2007 83 Female 8/21/2007 Physician Japan
Primary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/22/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/9/2007 Female 132 lb 9/12/2007 Physician Japan
Primary
Secondary
Concomitant
Urticaria Hospitalization 2/25/2007 Female 9/12/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Other Serious 9/7/2006 71 Male 168 lb 9/17/2007 Physician Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 1/22/2007 63 Female 150 lb 9/14/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/15/2006 Male 168 lb 9/21/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/16/2008 77 Female 1/28/2008 Pharmacist Japan
Primary
Concomitant
Flatulence Other Serious 75 Female 7/2/2008 Pharmacist Japan
Primary
Secondary
Large Intestine Carcinoma Death 3/6/2008 Female 7/22/2008 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 1/1/2008 Female 8/11/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Laryngeal Cancer Life Threatening 70 Female 8/11/2009 Japan
Primary
Concomitant
Lacunar Infarction Hospitalization 9/18/2009 70 Male 11/27/2009 Physician Japan
Primary
Concomitant
Lacunar Infarction Hospitalization 9/18/2009 70 12/21/2009 Physician Japan
Primary
Concomitant
Lacunar Infarction Hospitalization 9/18/2009 70 Male 1/20/2010 Physician Japan
Primary
Concomitant
Renal Disorder Hospitalization 2/1/2010 Male 3/18/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death 12/9/2008 Female 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/28/2009 Female 3/30/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 Female 3/31/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Retinal Exudates Other Serious 8/10/2009 62 Female 340 lb 4/5/2010 Physician Japan
Primary
Secondary
Concomitant
Glomerulonephritis Acute Other Serious 3/16/2010 61 Female 126 lb 4/6/2010 Physician Japan
Primary
Concomitant
Renal Failure Death 5/28/2008 76 Male 132 lb 4/7/2010 Physician Japan
Primary
Concomitant
Bradycardia Life Threatening 3/21/2010 68 Female 132 lb 4/14/2010 Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 7/15/2008 54 Male 108 lb 4/14/2010 Physician Japan
Primary
Concomitant
Retinal Exudates Other Serious 8/10/2009 62 Female 340 lb 4/15/2010 Physician Japan
Primary
Secondary
Concomitant
Femoral Neck Fracture Hospitalization 12/8/2008 71 Male 114 lb 4/16/2010 Physician Japan
Primary
Secondary
Concomitant
Retinal Exudates Other Serious 8/10/2009 62 Female 150 lb 4/19/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/4/2010 81 Male 106 lb 4/22/2010 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 3/28/2010 57 Female 4/22/2010 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/28/2009 75 Female 4/23/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/27/2010 57 Female 132 lb 4/26/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Other Serious 9/7/2006 71 Male 168 lb 4/26/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 3/27/2010 57 Female 132 lb 5/3/2010 Physician Japan
Primary
Secondary
Concomitant
Cataract Hospitalization 4/10/2009 68 Female 132 lb 5/5/2010 Physician Germany
Primary
Concomitant
Death Death 3/1/2010 70 Female 5/12/2010 Physician Japan
Primary
Concomitant
Hypothyroidism Other Serious 7/2/2009 Male 109 lb 5/12/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 3/27/2010 57 Female 132 lb 5/13/2010 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/4/2010 81 Male 106 lb 5/21/2010 Physician Japan
Primary
Concomitant
Malaise Other Serious 4/20/2010 79 Male 158 lb 5/27/2010 Pharmacist Japan
Primary
Concomitant
Sepsis Hospitalization 3/27/2010 57 Female 132 lb 5/28/2010 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 11/23/2009 47 Male 157 lb 5/31/2010 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Other Serious 7/2/2009 Male 109 lb 5/31/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 11/5/2009 78 Male 161 lb 6/2/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/24/2008 62 Female 6/4/2010 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 3/27/2010 57 Female 132 lb 6/8/2010 Physician Japan
Primary
Secondary
Surgery Other Serious 4/1/2010 23 Male 6/8/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 11/24/2008 66 Male 128 lb 6/10/2010 Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 3/27/2010 57 Female 132 lb 7/23/2010 Physician Japan
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 9/5/2008 59 Female 7/27/2010 Physician Japan
Primary
Secondary
Concomitant
Sinoatrial Block Hospitalization 9/16/2010 26 Female 60 lb 10/22/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2010 64 Male 10/22/2010 Physician Japan
Primary
Secondary
Lacunar Infarction Hospitalization 9/18/2009 70 12/21/2009 Physician Japan
Primary
Concomitant
Renal Failure Death 10/24/2010 86 Male 93 lb 3/8/2011 Consumer Japan
Primary
Concomitant
Cancer Pain Life Threatening 10/24/2010 86 Male 93 lb 3/18/2011 Consumer Japan
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 10/17/2007 74 Female 4/19/2011 Japan
Primary
Concomitant
Dizziness Hospitalization 11/29/2010 68 Female 5/6/2011 Physician Japan
Primary
Secondary
Interstitial Lung Disease Death 4/18/2011 76 Male 5/24/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 3/17/2011 80 Female 110 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/4/2009 75 Female 108 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Haemorrhage Subcutaneous Hospitalization 4/28/2009 75 Female 5/31/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Amnesia Other Serious 1/26/2011 70 Female 110 lb 5/31/2011 Pharmacist Japan
Primary
Concomitant
Hypothyroidism Hospitalization 7/29/2009 67 Female 99 lb 6/3/2011 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 4/16/2010 70 Male 101 lb 6/3/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 4/18/2011 76 Male 6/7/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 4/23/2011 63 Female 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
Shock Life Threatening 10/14/2010 57 Female 128 lb 6/10/2011 Consumer Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 3/25/2010 60 Male 6/14/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 4/18/2011 76 Male 6/21/2011 Other Health Professional Japan
Primary
Concomitant
Infusion Related Reaction Hospitalization 12/4/2009 65 Male 150 lb 6/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/23/2011 63 Female 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebral Ischaemia Hospitalization 6/11/2011 81 Female 6/27/2011 Consumer Japan
Primary
Concomitant
Cerebral Ischaemia Life Threatening 6/11/2011 81 Female 82 lb 7/1/2011 Physician Japan
Primary
Concomitant
Pneumonia Influenzal Death 1/16/2011 54 Female 106 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/23/2011 63 Female 7/6/2011 Physician Japan
Primary
Secondary
Concomitant
Haemorrhage Subcutaneous Hospitalization 4/28/2009 75 Female 7/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Retinal Pigment Epithelial Tear Other Serious 3/4/2011 82 Male 7/18/2011 Consumer Switzerland
Primary
Concomitant
Respiratory Tract Infection Other Serious 3/3/2011 61 Female 7/20/2011 Physician Japan
Primary
Secondary
Concomitant
Tongue Discolouration Hospitalization 5/1/2011 85 Female 7/21/2011 Pharmacist Japan
Primary
Concomitant
Multi-organ Failure Life Threatening 1/16/2011 54 Female 106 lb 7/27/2011 Consumer Japan
Primary
Secondary
Concomitant
Retinal Pigment Epithelial Tear Other Serious 3/4/2011 82 Male 7/27/2011 Other Health Professional Switzerland
Primary
Concomitant
Blood Urea Increased Other Serious 6/14/2011 70 Male 7/31/2011 Pharmacist Japan
Primary
Concomitant
Influenza Life Threatening 1/16/2011 54 Female 106 lb 8/2/2011 Consumer Japan
Primary
Secondary
Concomitant
Retinal Pigment Epithelial Tear Other Serious 3/4/2011 82 Male 132 lb 8/4/2011 Physician Switzerland
Primary
Concomitant
Bradycardia Other Serious 6/1/2011 71 Male 8/5/2011 Physician Japan
Primary
Concomitant
Retinal Pigment Epithelial Tear Other Serious 3/4/2011 82 Male 8/5/2011 Consumer Switzerland
Primary
Concomitant
Retinal Pigment Epithelial Tear Other Serious 3/4/2011 82 Male 132 lb 8/5/2011 Physician Switzerland
Primary
Concomitant
Bradycardia Hospitalization 6/24/2011 71 Male 8/16/2011 Physician Japan
Primary
Concomitant
Faeces Discoloured Death 5/25/2011 89 Female 101 lb 8/31/2011 Physician Japan
Primary
Concomitant
Urine Output Decreased Hospitalization 8/7/2011 79 Male 8/31/2011 Physician Japan
Primary
Secondary
Concomitant
Oral Disorder Other Serious 2/1/2011 73 Male 99 lb 9/8/2011 Physician Japan
Primary
Concomitant
Dry Skin Hospitalization 12/7/2010 67 Male 110 lb 9/14/2011 Physician Japan
Primary
Secondary
Concomitant
Hypoproteinaemia Death Female 9/15/2011 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Disability 6/6/2011 13 Female 88 lb 9/20/2011 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 11/19/2010 63 Male 143 lb 9/28/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 8/2/2010 60 Male 143 lb 10/3/2011 Physician Japan
Primary
Concomitant
Blood Urea Increased Hospitalization 8/7/2011 79 Male 118 lb 10/10/2011 Physician Japan
Primary
Secondary
Concomitant
Speech Disorder Other Serious 8/4/2011 88 Female 10/12/2011 Other Health Professional Japan
Primary
Concomitant
Sepsis Other Serious 3/3/2011 61 Female 10/18/2011 Consumer Japan
Primary
Secondary
Concomitant
Blood Potassium Increased Death 12/7/2010 67 Male 110 lb 10/19/2011 Physician Japan
Primary
Secondary
Concomitant
Delirium Other Serious 8/4/2011 88 Female 10/24/2011 Other Health Professional Japan
Primary
Concomitant
Swelling Other Serious 2/1/2011 73 Male 99 lb 10/25/2011 Physician Japan
Primary
Concomitant
Pituitary Tumour Benign Other Serious 8/11/2011 10/26/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening Female 10/25/2011 Consumer Japan
Primary
Concomitant
Ileus Other Serious 4/22/2010 79 Male 158 lb 10/26/2011 Pharmacist Japan
Primary
Concomitant
Cerebral Ischaemia Life Threatening 6/11/2011 81 Female 82 lb 10/31/2011 Physician Japan
Primary
Concomitant
Ileus Other Serious 4/20/2010 79 Male 158 lb 10/31/2011 Physician Japan
Primary
Concomitant
Nerve Injury Other Serious 10/22/2011 76 Male 141 lb 10/28/2011 Consumer Japan
Primary
Secondary
Concomitant
Visual Impairment Death 6/6/2011 13 Female 88 lb 11/8/2011 Physician Japan
Primary
Concomitant
Neoplasm Progression Hospitalization 8/11/2011 11/16/2011 Physician Japan
Primary
Concomitant
Gastric Ulcer Hospitalization 4/17/2009 76 Female 11/17/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 11/24/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 12/7/2010 67 Male 110 lb 11/29/2011 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Other Serious 1/1/2010 70 Male 11/30/2011 Japan
Primary
Concomitant
Vascular Pseudoaneurysm Hospitalization 10/22/2011 76 Male 141 lb 12/2/2011 Consumer Japan
Primary
Concomitant
Pancytopenia Other Serious 11/17/2011 78 Male 12/6/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 12/15/2011 Physician Japan
Primary
Concomitant
Vascular Pseudoaneurysm Other Serious 10/22/2011 76 Male 141 lb 12/15/2011 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 11/17/2011 78 Male 12/19/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Pain Other Serious Male 12/19/2011 Physician Japan
Primary
Concomitant
Arthritis Bacterial Life Threatening 4/17/2009 76 Female 12/20/2011 Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 8/26/2011 69 Male 154 lb 12/21/2011 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 11/17/2011 78 Male 12/26/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/12/2011 79 Male 121 lb 12/28/2011 Physician Japan
Primary
Concomitant
Pleurisy Hospitalization 3/3/2010 71 Male 1/4/2012 Physician Japan
Primary
Concomitant
Cerebral Ischaemia Hospitalization 6/11/2011 81 Female 82 lb 1/5/2012 Consumer Japan
Primary
Concomitant
Dermatitis Acneiform Hospitalization 10/12/2010 60 Male 128 lb 1/8/2012 Physician Japan
Primary
Secondary
Concomitant
Eczema Other Serious 2/1/2011 66 Female 154 lb 1/12/2012 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 11/17/2011 78 Male 132 lb 1/23/2012 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 11/29/2011 75 Male 110 lb 1/24/2012 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Upper Other Serious 12/4/2011 73 Female 2/2/2012 Physician Japan
Primary
Concomitant
Retinal Pigment Epithelial Tear Other Serious 3/4/2011 82 Male 132 lb 2/13/2012 Japan
Primary
Secondary
Concomitant
Pancreatic Carcinoma Death 12/13/2010 71 Female 101 lb 2/15/2012 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome 5/31/2011 67 Female 154 lb 2/17/2012 Physician Japan
Primary
Secondary
Concomitant
Pancreatic Carcinoma Death 12/13/2010 71 Female 101 lb 2/20/2012 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 2/19/2012 57 Male 3/7/2012 Japan
Primary
Concomitant
Cerebral Ischaemia Hospitalization 6/11/2011 81 Female 82 lb 3/9/2012 Consumer Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/19/2012 60 Male 148 lb 3/9/2012 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Death 11/3/2010 80 Female 101 lb 3/13/2012 Physician Japan
Primary
Concomitant
Decreased Appetite Other Serious 2/19/2012 57 Male 3/16/2012 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/23/2011 64 Male 141 lb 3/16/2012 Physician Japan
Primary
Secondary
Concomitant
Dry Skin Hospitalization 12/7/2010 67 Male 110 lb 4/3/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data