Calcium Levofolinate combined with Elplat

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Other Serious 12/7/2005 Male 101 lb 2/4/2008 Other Health Professional Japan
Primary
Secondary
Small Intestinal Perforation Life Threatening 1/25/2008 Male 3/10/2008 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Life Threatening 1/25/2008 Male 3/21/2008 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Life Threatening 1/25/2008 Male 4/18/2008 Physician Japan
Primary
Secondary
Concomitant
Ileal Perforation Disability 12/6/2007 Male 117 lb 6/18/2008 Other Health Professional Japan
Primary
Secondary
Pulmonary Thrombosis Death 2/8/2008 Female 124 lb 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 3/14/2008 Male 7/3/2008 Physician Japan
Primary
Secondary
Tumour Haemorrhage Other Serious 5/26/2008 28 Male 121 lb 7/15/2008 Physician Japan
Primary
Secondary
Prinzmetal Angina Other Serious 12/9/2007 Male 7/23/2008 Physician Japan
Primary
Secondary
Concomitant
Ulcer Disability 6/4/2008 Female 1/2/2009 Physician Japan
Primary
Secondary
Acute Myocardial Infarction Hospitalization 12/11/2008 Male 1/2/2009 Physician Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 8/18/2008 Female 1/7/2009 Pharmacist United Kingdom
Primary
Secondary
Arrhythmia Death 10/31/2008 67 Male 1/8/2009 Physician Japan
Primary
Secondary
Intestinal Perforation Other Serious 61 Female 1/15/2009 Consumer Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 11/5/2008 Female 1/16/2009 Consumer United Kingdom
Primary
Concomitant
Shock Other Serious 11/6/2008 59 Male 1/23/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/20/2008 Male 110 lb 1/24/2009 Consumer Japan
Primary
Secondary
Concomitant
Shock Hospitalization 12/8/2008 49 Male 1/28/2009 Physician Japan
Primary
Secondary
Concomitant
Gastric Haemorrhage Hospitalization 12/9/2008 69 Male 1/28/2009 Consumer Japan
Primary
Secondary
Interstitial Lung Disease Hospitalization 12/3/2008 74 Male 110 lb 1/29/2009 Consumer Japan
Primary
Concomitant
Hypertension Life Threatening 11/25/2008 Male 146 lb 2/4/2009 Physician Japan
Primary
Secondary
Concomitant
Hypoaesthesia Oral Life Threatening 1/15/2008 Male 110 lb 2/11/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ileal Perforation Disability 12/6/2007 Male 117 lb 2/12/2009 Physician Japan
Primary
Secondary
Spinal Cord Infarction Disability 11/25/2008 Male 144 lb 2/12/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 11/9/2008 Male 2/13/2009 Consumer Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 2/3/2009 Male 128 lb 2/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 1/5/2009 Male 2/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Haemoptysis Life Threatening 9/5/2008 Male 2/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Perforation Hospitalization 1/20/2009 60 Male 2/20/2009 Physician Japan
Primary
Secondary
Leukoencephalopathy Life Threatening 1/18/2009 72 Female 2/20/2009 Physician Japan
Primary
Secondary
Shock Other Serious Male 146 lb 2/24/2009 Consumer United Kingdom
Primary
Concomitant
Gastrointestinal Perforation Death 2/2/2009 66 Male 2/25/2009 Physician Japan
Primary
Secondary
Sepsis Other Serious 11/9/2008 Male 2/26/2009 Consumer Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 12/8/2008 Male 101 lb 2/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Necrotising Fasciitis Death 2/2/2009 Male 3/2/2009 Physician Japan
Primary
Secondary
Duodenal Perforation Hospitalization 2/16/2009 Male 104 lb 3/2/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 1/24/2009 Male 3/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 1/9/2009 Male 137 lb 3/5/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Necrotising Fasciitis Death 2/2/2009 66 Male 3/9/2009 Physician Japan
Primary
Secondary
Interstitial Lung Disease Other Serious 12/8/2008 Male 101 lb 3/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 2/17/2009 Female 3/12/2009 Physician United Kingdom
Primary
Secondary
Interstitial Lung Disease Other Serious 2/3/2009 Male 128 lb 3/13/2009 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 7/4/2008 Male 181 lb 3/17/2009 Physician Japan
Primary
Secondary
Hypertension Life Threatening 11/25/2008 Male 146 lb 3/17/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 2/17/2009 Female 3/17/2009 Physician Japan
Primary
Secondary
Proteinuria Death 2/17/2009 Male 3/20/2009 Physician United Kingdom
Primary
Secondary
Neutrophil Count Decreased Other Serious 11/7/2007 Male 3/21/2009 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Other Serious 64 Male 3/25/2009 Pharmacist United Kingdom
Primary
Concomitant
Hepatic Encephalopathy Life Threatening 3/11/2009 Male 3/25/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Hospitalization 1/20/2009 Male 3/25/2009 Physician Japan
Primary
Secondary
Concomitant
Anorexia Life Threatening 3/1/2008 66 Male 3/25/2009 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 11/11/2008 Female 108 lb 3/25/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Proteinuria Death 2/17/2009 Male 3/26/2009 Physician United Kingdom
Primary
Secondary
Cholecystitis Acute Hospitalization 2/26/2009 Male 121 lb 3/30/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Convulsion Hospitalization 11/2/2008 Female 4/6/2009 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Perforation Life Threatening 8/27/2008 Female 100 lb 4/7/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/18/2009 Female 121 lb 4/9/2009 Consumer Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 8/18/2008 Female 4/10/2009 Pharmacist United Kingdom
Primary
Secondary
Rash Hospitalization 4/16/2009 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/3/2009 Male 128 lb 4/16/2009 Consumer United Kingdom
Primary
Secondary
Rash Hospitalization Male 4/21/2009 Consumer Japan
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 3/11/2009 Male 154 lb 4/21/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 2/18/2009 Female 121 lb 4/22/2009 Consumer Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Hospitalization 11/5/2008 Male 4/24/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/1/2007 Male 4/24/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/4/2008 Male 181 lb 4/27/2009 Physician Japan
Primary
Secondary
Convulsion Hospitalization 1/1/2008 Female 101 lb 4/30/2009 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/22/2008 Male 110 lb 4/30/2009 Physician Japan
Primary
Secondary
Concomitant
Hyperammonaemia Hospitalization 3/11/2009 Male 154 lb 5/21/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaphylactoid Reaction Hospitalization 70 Female 5/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Perforation Death 5/3/2009 Female 130 lb 5/21/2009 Consumer United Kingdom
Primary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 5/14/2009 Female 5/25/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Vaginal Fistula Hospitalization 4/30/2009 Female 5/27/2009 Physician Japan
Primary
Secondary
Disseminated Intravascular Coagulation Life Threatening 5/14/2009 Female 5/27/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Anorexia Life Threatening 3/1/2008 66 Male 165 lb 5/25/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/10/2009 Male 5/28/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Shock Other Serious 5/7/2009 Male 5/29/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 5/14/2009 Female 6/2/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 4/1/2009 Female 6/2/2009 Other Health Professional Japan
Primary
Secondary
Multi-organ Failure Other Serious 4/17/2009 Female 6/2/2009 Consumer United Kingdom
Primary
Secondary
Interstitial Lung Disease Other Serious 3/31/2009 Male 128 lb 6/3/2009 Consumer United Kingdom
Primary
Secondary
Interstitial Lung Disease Other Serious 12/8/2008 Male 101 lb 6/4/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Perforation Death 5/3/2009 Female 130 lb 6/5/2009 Consumer United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 4/28/2009 Male 6/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/9/2008 Male 6/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 2/7/2009 Male 6/10/2009 Pharmacist United Kingdom
Primary
Concomitant
Anaphylactoid Reaction Hospitalization 5/1/2009 Female 6/11/2009 Consumer Japan
Primary
Secondary
Concomitant
Melaena Hospitalization 4/12/2009 Female 6/18/2009 Physician Japan
Primary
Secondary
Concomitant
Female Genital Tract Fistula Hospitalization 4/13/2009 Female 6/25/2009 Physician Japan
Primary
Secondary
Concomitant
Eosinophilic Pneumonia Other Serious 4/1/2009 Male 7/1/2009 Physician United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 7/6/2008 51 Male 7/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Disease Progression Death 6/9/2008 Male 147 lb 7/10/2009 Physician Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 11/5/2008 Female 7/14/2009 Consumer United Kingdom
Primary
Concomitant
Necrotising Fasciitis Other Serious 5/1/2009 65 Male 7/15/2009 Physician Japan
Primary
Secondary
Anaphylactoid Reaction Hospitalization 5/1/2009 Female 7/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rectal Cancer Metastatic Hospitalization 4/13/2009 Female 7/16/2009 Physician Japan
Primary
Secondary
Concomitant
Eosinophilic Pneumonia Other Serious 4/1/2009 Male 7/22/2009 Physician United Kingdom
Primary
Secondary
Neutrophil Count Decreased Life Threatening 9/5/2008 Male 7/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 5/14/2009 Female 106 lb 7/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Eosinophilic Pneumonia Other Serious 3/17/2009 Male 8/3/2009 Physician United Kingdom
Primary
Secondary
Urinary Retention Hospitalization 4/28/2009 Male 8/4/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 4/28/2009 Male 8/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Shock Life Threatening 5/12/2009 Male 8/28/2009 Consumer Japan
Primary
Secondary
Concomitant
Shock Life Threatening 5/12/2009 Male 8/28/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sense Of Oppression Other Serious 1/27/2009 Female 9/11/2009 Physician Japan
Primary
Secondary
Urinary Retention Hospitalization 4/28/2009 Male 9/15/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Speech Disorder Other Serious 6/2/2009 9/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Lymphocyte Stimulation Test Positive Hospitalization 2/9/2009 Male 110 lb 10/13/2009 Consumer Japan
Primary
Secondary
Jaundice Death 60 Female 10/14/2009 Consumer United Kingdom
Primary
Concomitant
Anaphylactic Shock Hospitalization 10/1/2009 63 Female 108 lb 10/14/2009 Physician United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/7/2009 Male 10/27/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Death 11/9/2008 Male 11/2/2009 Consumer Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 47 Female 11/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 63 Male 11/5/2009 Consumer Japan
Primary
Secondary
Spinal Cord Infarction Disability 11/25/2008 Male 144 lb 11/16/2009 Physician Japan
Primary
Concomitant
Small Intestinal Perforation Life Threatening 1/27/2009 Female 130 lb 11/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/7/2009 Male 11/25/2009 Consumer United Kingdom
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 11/19/2009 Male 12/4/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 2/1/2008 Male 12/8/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 4/24/2008 65 Male 12/10/2009 Other Health Professional Japan
Primary
Concomitant
Nausea Other Serious 6/30/2008 34 Male 143 lb 12/10/2009 Physician Japan
Primary
Secondary
Concomitant
Jejunal Perforation Life Threatening 12/11/2008 Male 106 lb 12/15/2009 Physician Japan
Primary
Secondary
Concomitant
Colonic Fistula Hospitalization 10/8/2009 58 Male 12/15/2009 Physician Japan
Primary
Secondary
Concomitant
Rectal Perforation Life Threatening 6/1/2009 Male 131 lb 12/18/2009 Other Health Professional Japan
Primary
Concomitant
Altered State Of Consciousness Hospitalization 12/11/2009 71 Female 12/24/2009 Other Health Professional Japan
Primary
Secondary
Gastrointestinal Perforation Hospitalization 11/11/2009 43 Female 1/8/2010 Physician Japan
Primary
Secondary
Shock Haemorrhagic Life Threatening 7/1/2009 55 Male 1/12/2010 Consumer Japan
Primary
Secondary
Altered State Of Consciousness Hospitalization 12/10/2009 71 Female 1/19/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Hospitalization 1/6/2010 53 Female 1/26/2010 Consumer Japan
Primary
Secondary
Disease Progression Death 7/1/2008 55 Female 1/27/2010 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 8/23/2007 Male 132 lb 1/29/2010 Physician Japan
Primary
Concomitant
Illusion Other Serious 63 Female 2/1/2010 Other Health Professional Japan
Primary
Concomitant
Shock Haemorrhagic Life Threatening 7/1/2009 55 Male 2/3/2010 Consumer United Kingdom
Primary
Secondary
Tumour Haemorrhage Other Serious 60 2/3/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 1/19/2010 Male 2/8/2010 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Other Serious 1/19/2010 79 Male 2/16/2010 Other Health Professional Japan
Primary
Secondary
Renal Failure Acute Other Serious 73 Male 2/18/2010 Physician Japan
Primary
Secondary
Interstitial Lung Disease Other Serious 1/19/2010 79 Male 2/18/2010 Other Health Professional Japan
Primary
Secondary
Colonic Fistula Hospitalization 10/8/2009 58 Male 2/22/2010 Physician Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 6/27/2008 Male 106 lb 2/23/2010 Physician Japan
Primary
Concomitant
Rectal Perforation Hospitalization 1/27/2010 60 Male 2/26/2010 Consumer Japan
Primary
Secondary
Interstitial Lung Disease Other Serious 1/19/2010 79 Male 3/3/2010 Other Health Professional Japan
Primary
Secondary
Porcelain Gallbladder Other Serious 12/1/2009 62 Male 3/8/2010 Physician Japan
Primary
Secondary
Interstitial Lung Disease Other Serious 1/19/2010 79 Male 3/8/2010 Other Health Professional Japan
Primary
Secondary
Peritonitis Hospitalization 43 Female 3/8/2010 Physician Japan
Primary
Secondary
Vomiting Other Serious 10/28/2009 51 Male 3/17/2010 Physician Japan
Primary
Secondary
Concomitant
Porcelain Gallbladder Hospitalization 12/23/2009 Male 161 lb 3/18/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/2/2010 Female 3/23/2010 Pharmacist Japan
Primary
Secondary
Porcelain Gallbladder Hospitalization 12/23/2009 62 Male 3/31/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/2/2010 58 Female 4/2/2010 Pharmacist Japan
Primary
Secondary
Concomitant

Drug Data