Calcium Folinate combined with Fluorouracil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Infection Death 74 Male 3/1/2006 United Kingdom
Primary
Concomitant
Salivary Hypersecretion Other Serious 1/31/2006 48 Female 115 lb 3/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Life Threatening 5/9/2006 58 Male 207 lb 5/16/2006 Physician China
Primary
Secondary
Concomitant
Wheezing Life Threatening 5/9/2006 58 Male 207 lb 5/19/2006 Physician China
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/1/2005 80 Male 210 lb 2/24/2006 United States
Primary
Secondary
Concomitant
Pain In Extremity Disability 67 Male 6/1/2006 Physician China
Primary
Secondary
Concomitant
Pneumonia Life Threatening 5/18/2006 Male 6/22/2006 Other Health Professional Turkey
Primary
Secondary
Loss Of Consciousness Hospitalization 5/10/2006 59 Male 7/3/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/23/2006 Male 146 lb 7/6/2006 Other Health Professional
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 5/18/2006 Male 7/12/2006 Physician Turkey
Primary
Secondary
Acute Promyelocytic Leukaemia Death 5/1/1996 65 Female 7/12/2006 Physician
Primary
Secondary
Concomitant
Infection Other Serious 58 Female 7/15/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 8/19/2006 France
Primary
Secondary
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 8/19/2006 France
Primary
Secondary
Confusional State Other Serious 7/6/2006 58 Female 8/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis Hospitalization 6/20/2005 33 Female 9/28/2006 Physician France
Primary
Secondary
Concomitant
Vith Nerve Paralysis Other Serious Female 9/28/2006 Physician Germany
Primary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 11/17/2006 France
Primary
Secondary
Cerebrovascular Accident Hospitalization 9/13/2006 47 Male 11/9/2006 United Kingdom
Primary
Concomitant
Diarrhoea Haemorrhagic Hospitalization 11/7/2006 79 Male 196 lb 12/5/2006 Consumer France
Primary
Secondary
Concomitant
Peritonitis Bacterial Other Serious 20 Male 12/28/2006 Bulgaria
Primary
Secondary
Demyelinating Polyneuropathy Other Serious 4/5/2006 63 Male 1/4/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Infection Hospitalization 1/15/2007 Female 273 lb 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Ventricular Arrhythmia Hospitalization 1/10/2007 56 Female 194 lb 2/5/2007 Physician Denmark
Primary
Secondary
Concomitant
Infection Hospitalization 1/15/2007 Female 273 lb 2/7/2007 United Kingdom
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 6/10/2006 58 Female 183 lb 2/15/2007 France
Primary
Secondary
Platelet Count Decreased Other Serious Male 2/15/2007 France
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 1/10/2007 56 Female 194 lb 2/16/2007 Physician Denmark
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 7/30/2006 Female 137 lb 2/20/2007 Physician France
Primary
Concomitant
Wheezing Life Threatening 1/25/2007 73 Male 146 lb 2/21/2007 Other Health Professional Japan
Primary
Concomitant
Peripheral Sensory Neuropathy Disability 12/1/2006 58 Female 143 lb 2/22/2007 Other Health Professional Austria
Primary
Secondary
Peripheral Sensory Neuropathy Disability 12/1/2006 58 Female 143 lb 3/13/2007 Other Health Professional Austria
Primary
Secondary
Neutropenia Hospitalization 2/18/2007 3/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 3/24/2006 Female 115 lb 3/16/2007 Physician France
Primary
Concomitant
Stomatitis Death 12/10/2006 73 Male 146 lb 3/19/2007 Other Health Professional Japan
Primary
Concomitant
Rectal Haemorrhage Other Serious 2/1/2007 70 Male 3/21/2007 Physician France
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 1/1/2007 74 Female 4/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 1/24/2007 Male 154 lb 4/6/2007 France
Primary
Concomitant
Death Death 2/18/2007 Male 192 lb 4/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 1/1/2007 74 Female 4/24/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/18/2007 Male 5/11/2007 Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 5/11/2007 51 Male 5/21/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/18/2007 Male 5/24/2007 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/7/2007 Male 6/6/2007 Japan
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 4/4/2007 Male 154 lb 6/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 62 Male 6/19/2007 New Zealand
Primary
Secondary
Hepatocellular Damage Other Serious 66 Male 6/20/2007 New Zealand
Primary
Secondary
Liver Injury Other Serious 62 Male 6/16/2007 Other Health Professional New Zealand
Primary
Secondary
Liver Injury Other Serious 66 Male 6/16/2007 Other Health Professional New Zealand
Primary
Secondary
Balance Disorder Hospitalization 1/1/2006 Female 6/21/2007 Physician
Primary
Concomitant
Paresis Hospitalization 6/1/2007 Male 6/21/2007 Physician
Primary
Concomitant
Rectal Ulcer Hospitalization 9/8/2005 Male 205 lb 7/12/2007 Pharmacist Germany
Primary
Secondary
Jaundice Hospitalization 6/27/2007 Male 7/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 6/27/2007 41 Male 7/9/2007 Italy
Primary
Secondary
Concomitant
Hypovolaemia Life Threatening 10/25/2005 76 Male 7/24/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 7/6/2007 55 Male 7/24/2007 Physician Japan
Primary
Secondary
Concomitant
Jaundice Hospitalization 6/27/2007 Male 7/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 6/27/2007 41 Male 7/19/2007 Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/17/2005 74 Male 170 lb 7/26/2007 Physician United States
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 8/8/2007 40 Female 8/21/2007 Consumer Italy
Primary
Secondary
Reaction To Food Additive Hospitalization 12/8/2003 Female 158 lb 8/31/2007 United States
Primary
Secondary
Concomitant
Infection Hospitalization 1/15/2007 Female 273 lb 10/16/2007 United Kingdom
Primary
Secondary
Concomitant
Lower Limb Fracture Disability 8/13/2007 Male 220 lb 10/23/2007 Pharmacist Germany
Primary
Concomitant
Interacting
Infection Hospitalization 1/15/2007 Female 273 lb 10/31/2007 United Kingdom
Primary
Secondary
Concomitant
Lower Limb Fracture Disability 8/13/2007 Male 220 lb 10/31/2007 Pharmacist Germany
Primary
Concomitant
Interacting
Vomiting Hospitalization 4/11/2003 Female 170 lb 11/8/2007 United States
Primary
Secondary
Concomitant
Laryngospasm Life Threatening 9/24/2006 58 Male 11/13/2007 Physician China
Primary
Concomitant
Pyrexia Hospitalization 11/2/2007 11/19/2007 Australia
Primary
Secondary
Concomitant
Red Cell Distribution Width Increased Hospitalization 8/15/2003 Male 115 lb 11/15/2007 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 5/18/2006 Male 11/27/2007 Physician Turkey
Primary
Secondary
Urinary Tract Infection Hospitalization 11/2/2007 Female 12/5/2007 Australia
Primary
Secondary
Concomitant
Lower Limb Fracture Other Serious 2/9/2007 Male 227 lb 12/14/2007 Physician Germany
Primary
Concomitant
Interacting
Anastomotic Complication Hospitalization 11/7/2007 Male 183 lb 1/25/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Other Serious 1/8/2008 Female 121 lb 2/1/2008 United Kingdom
Primary
Secondary
Concomitant
Asthma Hospitalization 1/28/2008 Female 2/8/2008 Japan
Primary
Secondary
Vomiting Other Serious 1/8/2008 Female 121 lb 2/13/2008 United Kingdom
Primary
Secondary
Concomitant
Asthma Hospitalization 1/28/2008 Female 2/15/2008 Japan
Primary
Secondary
Asthma Hospitalization 1/28/2008 Female 2/20/2008 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/8/2008 Female 121 lb 2/21/2008 United Kingdom
Primary
Secondary
Concomitant
Perineal Abscess Hospitalization 9/10/2006 Male 198 lb 3/6/2008 Consumer United Kingdom
Primary
Secondary
Small Intestinal Obstruction Hospitalization 1/8/2008 Female 121 lb 4/23/2008 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/11/2008 Male 5/29/2008 Physician Italy
Primary
Secondary
Concomitant
Perineal Abscess Hospitalization 9/10/2006 Male 198 lb 6/3/2008 Consumer United Kingdom
Primary
Secondary
Cerebral Infarction Other Serious 5/20/2008 Male 203 lb 6/3/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 5/20/2008 65 Male 203 lb 6/4/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatitis Hospitalization 3/3/2008 Male 6/27/2008 Other Health Professional Japan
Primary
Concomitant
Nail Infection Other Serious 10/1/2007 60 Female 172 lb 7/8/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 6/19/2008 Female 176 lb 7/15/2008 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Haemolytic Uraemic Syndrome Death 5/2/2008 Female 7/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 5/20/2008 65 Male 203 lb 7/24/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 12/14/2007 64 Female 172 lb 7/22/2008 Consumer Portugal
Primary
Secondary
Cutaneous Lupus Erythematosus Other Serious 77 Female 7/30/2008 Austria
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 7/23/2008 Male 101 lb 8/5/2008 Australia
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 7/23/2008 Male 101 lb 8/8/2008 Australia
Primary
Secondary
Concomitant
Death Death 8/7/2008 Male 134 lb 8/13/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2008 Male 160 lb 8/14/2008 Japan
Primary
Secondary
Concomitant
Death Death 8/7/2008 Male 134 lb 8/18/2008 India
Primary
Secondary
Concomitant
Visual Impairment Other Serious 8/6/2008 Female 8/18/2008 Physician Japan
Primary
Secondary
Haemolytic Uraemic Syndrome Death 5/2/2008 Female 8/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2008 Male 154 lb 8/20/2008 Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/14/2008 58 Male 8/20/2008 Other Health Professional Japan
Primary
Secondary
Ileus Hospitalization 8/10/2008 Female 8/21/2008 Taiwan, Province Of China
Primary
Secondary
Concomitant
Vomiting Other Serious 8/5/2008 Female 112 lb 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Death Death 8/7/2008 Male 134 lb 8/26/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2008 Male 154 lb 8/27/2008 Japan
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 5/14/2008 65 Male 203 lb 8/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2008 Male 132 lb 8/28/2008 India
Primary
Secondary
Concomitant
Death Death 8/1/2008 Female 209 lb 8/28/2008 Hungary
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/10/2008 Female 104 lb 8/29/2008 Taiwan, Province Of China
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 73 Male 9/3/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Cardiac Failure Death 8/18/2008 Female 209 lb 9/3/2008 Hungary
Primary
Secondary
Concomitant
Encephalopathy Other Serious 5/14/2008 65 Male 203 lb 9/4/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Neutropenia Life Threatening 7/19/2005 Female 9/4/2008 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2008 Male 132 lb 9/5/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2008 Male 132 lb 9/8/2008 India
Primary
Secondary
Concomitant
Acute Coronary Syndrome Other Serious 6/19/2008 Male 9/9/2008 Other Health Professional Germany
Primary
Concomitant
Colonic Obstruction Death 9/1/2008 Male 172 lb 9/9/2008 Poland
Primary
Secondary
Concomitant
Neutropenia Life Threatening 7/19/2005 Female 9/10/2008 France
Primary
Secondary
Concomitant
Colonic Obstruction Death 9/1/2008 Male 172 lb 9/12/2008 Poland
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 9/4/2008 Female 9/12/2008 Japan
Primary
Secondary
Urine Output Decreased Other Serious 8/6/2008 Female 112 lb 9/15/2008 Physician Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 9/4/2008 Female 77 lb 9/18/2008 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/10/2008 Female 104 lb 9/18/2008 Taiwan, Province Of China
Primary
Secondary
Concomitant
Death Death 9/10/2008 Female 121 lb 9/24/2008 Czech Republic
Primary
Secondary
Concomitant
Perineal Abscess Hospitalization 9/10/2006 Male 198 lb 9/24/2008 Consumer United Kingdom
Primary
Secondary
Intestinal Obstruction Hospitalization 9/4/2008 Female 77 lb 9/25/2008 Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 9/20/2008 Female 106 lb 9/25/2008 South Africa
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 5/12/2008 65 Male 203 lb 9/26/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Death Death 9/10/2008 Female 121 lb 9/26/2008 Czech Republic
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 5/12/2008 Male 203 lb 9/29/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
No Adverse Event 1/8/2008 Female 121 lb 10/1/2008 United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 9/20/2008 Male 106 lb 10/1/2008 South Africa
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 5/12/2008 65 Male 203 lb 10/9/2008 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/26/2008 Male 10/9/2008 Germany
Primary
Secondary
Concomitant
Respiratory Failure Death 9/20/2008 Male 106 lb 10/13/2008 South Africa
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2008 Male 132 lb 10/14/2008 India
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/26/2008 Male 10/15/2008 Germany
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/18/2008 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/11/2008 Female 95 lb 10/20/2008 Bulgaria
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/11/2008 Female 95 lb 10/24/2008 Bulgaria
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/27/2008 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/4/2008 Male 10/27/2008 Other Health Professional Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/29/2008 Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 11/3/2008 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/21/2008 Female 95 lb 11/3/2008 Bulgaria
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 12/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Diarrhoea Death 2/18/2007 Male 12/18/2008 Physician Germany
Primary
Secondary
Concomitant
Death Death 2/18/2007 Male 192 lb 12/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/7/2008 Male 123 lb 12/19/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 12/8/2008 12/19/2008 Other Health Professional Australia
Primary
Secondary

Drug Data