Calcium Carbonate combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rhabdomyolysis Death 11/19/2005 Male 1/13/2006 Italy
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 11/19/2005 73 Male 1/20/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Rhabdomyolysis Death 11/19/2005 Male 1/19/2006 Italy
Primary
Secondary
Concomitant
Extrasystoles Other Serious 12/1/2005 Male 1/20/2006 Physician Sweden
Primary
Concomitant
Urticaria Required Intervention 6/28/2005 Male 168 lb Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/4/2005 73 Male 1/27/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Sensory Loss Hospitalization 11/2/2005 Male 1/26/2006 Italy
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/5/2004 59 Female 2/8/2006 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 2/26/2006 64 Female 195 lb 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 5/1/2005 80 Female 5/5/2006 Physician Germany
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2005 Male 5/8/2006 Physician Sweden
Primary
Concomitant
Sensory Loss Hospitalization 11/2/2005 Male 5/17/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/10/2005 54 Female 5/24/2006 Pharmacist Australia
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 12/1/2005 Male 6/6/2006 Physician Sweden
Primary
Concomitant
Skin Lesion 1/1/2005 Male 161 lb 8/4/2006 Other Health Professional United States
Primary
Concomitant
Renal Disorder Hospitalization 11/6/2000 53 Female 104 lb 8/21/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2005 Male 8/21/2006 Physician Sweden
Primary
Concomitant
Renal Disorder Hospitalization 11/6/2000 53 Female 104 lb 8/29/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/4/2006 73 Female 8/16/2006 United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 5/1/2005 80 Female 152 lb 8/30/2006 Physician Germany
Primary
Concomitant
Renal Disorder Hospitalization 11/6/2000 53 Female 104 lb 9/11/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Sensory Loss Hospitalization 11/2/2005 Male 9/14/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 12/1/2005 Male 10/12/2006 Physician Sweden
Primary
Concomitant
Milk-alkali Syndrome Hospitalization 72 Male 11/29/2006
Primary
Secondary
Concomitant
Somnolence Other Serious 7/12/2006 74 Female 112 lb 1/23/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 63 Female 3/5/2007 United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 78 Male 4/30/2007 Other Health Professional United States
Primary
Concomitant
Rash Required Intervention 7/9/2007 47 Female 188 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 5/24/2007 62 Male 154 lb 10/31/2007 Greece
Primary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 11/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2007 62 Male 154 lb 12/13/2007 Greece
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2007 62 Male 154 lb 12/19/2007 Greece
Primary
Concomitant
Abdominal Wall Abscess Hospitalization 3/29/2007 Female 134 lb 12/28/2007 United Kingdom
Primary
Concomitant
Death Death 8/14/2007 68 Male 112 lb 2/25/2008 Physician United States
Primary
Concomitant
Muscle Injury Other Serious 3/20/2008 74 Female 4/2/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/14/2007 91 Female 4/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Muscle Injury Other Serious 3/20/2008 74 Female 152 lb 5/2/2008 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/7/2008 62 Female 6/6/2008 Sweden
Primary
Concomitant
Pericarditis Hospitalization 3/2/2007 Male 152 lb 2/2/2009 Physician Poland
Primary
Concomitant
Hypokalaemia Other Serious 3/25/2009 75 Female 4/14/2009 Pharmacist United Kingdom
Primary
Concomitant
Proctitis Hospitalization 2/3/2009 Male 4/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 3/25/2009 75 Female 4/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Proctitis Hospitalization 2/3/2009 Male 4/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 5/12/2009 80 Female 75 lb 5/29/2009 Physician Japan
Primary
Concomitant
Interacting
International Normalised Ratio Increased Life Threatening 5/12/2009 80 Female 75 lb 6/9/2009 Physician Japan
Primary
Concomitant
Interacting
Rash Pruritic 1/1/2008 75 Female 203 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Vitamin D Deficiency Hospitalization 72 Female 9/23/2009 United States
Primary
Concomitant
Urticaria 1/1/2008 75 Female 203 lb 10/9/2009 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 8/4/2009 84 Female 10/23/2009 United Kingdom
Primary
Concomitant
Head Injury Hospitalization 10/25/2009 92 Male 12/1/2009 Pharmacist United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 9/4/2009 50 12/2/2009 Physician Japan
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/9/2009 Male 158 lb 12/17/2009 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Wound Infection Other Serious 8/24/2007 Female 157 lb 12/17/2009 Pharmacist United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/9/2009 Male 160 lb 12/23/2009 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Cerebrovascular Accident Hospitalization 12/9/2009 Male 162 lb 12/28/2009 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Cerebrovascular Accident Hospitalization 12/9/2009 Male 162 lb 1/5/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Cerebrovascular Accident Hospitalization 12/9/2009 Male 162 lb 1/7/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 Male 162 lb 1/20/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 Male 161 lb 2/8/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 Male 161 lb 2/8/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Hyponatraemia Other Serious 98 Female 3/15/2010 United Kingdom
Primary
Concomitant
Spinal Column Stenosis Disability 1/11/2010 60 Male 4/22/2010 Other Health Professional Japan
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 75 Male 161 lb 5/15/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Confusional State Hospitalization 7/6/2006 74 Male 170 lb 7/5/2010 Physician Netherlands
Primary
Concomitant
Tobacco User 10/1/2006 53 Male 178 lb 7/8/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Death 6/6/2009 69 Male 7/9/2010 Physician United Kingdom
Primary
Concomitant
Bronchitis 12/1/2006 60 Female 130 lb 7/9/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 75 Male 152 lb 8/2/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 75 Male 149 lb 9/9/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 75 Male 149 lb 10/5/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Condition Aggravated Other Serious 45 Female 10/12/2010 Physician
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 10/13/2010 Physician United States
Primary
Secondary
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 75 Male 150 lb 10/20/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 45 Female 11/3/2010 Physician United States
Primary
Secondary
Mental Disorder Other Serious 45 Female 11/24/2010 Physician United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 11/8/2010 United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 12/1/2010 Other Health Professional United States
Primary
Secondary
Hyponatraemia Other Serious 98 Female 12/7/2010 United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/1/2010 81 Female 1/6/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2010 81 Female 1/6/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Other Serious 11/1/2010 81 Female 1/6/2011 Consumer United States
Primary
Concomitant
Carotid Artery Stenosis Hospitalization 12/1/2009 75 Male 150 lb 1/28/2011 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Device Malfunction Disability 12/1/2009 75 Male 150 lb 2/9/2011 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Injury Hospitalization 12/11/2003 53 Male 158 lb 4/5/2011 Lawyer United States
Primary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anhedonia Other Serious 10/30/2003 69 Female 170 lb 5/19/2011 Consumer United States
Primary
Concomitant
Disturbance In Attention Disability 1/1/2009 70 Female 181 lb 5/24/2011 Physician United States
Primary
Concomitant
Myocardial Infarction Death 5/6/2011 71 Male 6/29/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Disease Other Serious 12/16/2010 69 Male 269 lb 6/30/2011 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 5/6/2011 71 Male 7/22/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Death 12/1/2007 54 Male 163 lb 7/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Output Decreased Other Serious 12/1/2007 54 Male 163 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mean Cell Haemoglobin Decreased Hospitalization 7/4/2011 71 Female 110 lb 7/29/2011 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 7/13/2009 77 Male 8/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Erythema 4/17/2011 66 Female 218 lb 8/6/2011 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 3/7/2011 85 Male 8/12/2011 Other Health Professional United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Disability 12/1/2009 75 Male 150 lb 9/7/2011 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Muscle Strain Hospitalization 7/4/2011 71 Female 110 lb 8/29/2011 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Anxiety Other Serious 5/31/2011 69 Male 9/19/2011 Consumer United States
Primary
Secondary
Concomitant
Hypercholesterolaemia 1/1/2008 56 Female 198 lb 9/22/2011 Consumer United States
Primary
Concomitant
Dyspepsia Hospitalization 7/24/2007 69 Female 133 lb 10/24/2011 Consumer United States
Primary
Secondary
Concomitant
Fluid Overload Other Serious 9/14/2011 77 Male 173 lb 11/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hypercholesterolaemia Hospitalization 5/1/2008 41 Female 225 lb 11/9/2011 Physician United States
Primary
Concomitant
Device Malfunction Other Serious 12/1/2009 75 Male 149 lb 11/15/2011 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Cholelithiasis Death 12/1/2007 54 Male 163 lb 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Pseudomembranous Colitis Other Serious 5/14/2010 65 Male 11/30/2011 Other Health Professional Japan
Primary
Concomitant
Pseudomembranous Colitis Other Serious 5/14/2010 65 Male 11/30/2011 Other Health Professional Japan
Primary
Concomitant
Pseudomembranous Colitis Other Serious 5/14/2010 65 Male 11/30/2011 Other Health Professional Japan
Primary
Concomitant
Dysstasia Other Serious Female 12/8/2011 Consumer Brazil
Primary
Concomitant
Suicide Attempt Other Serious 12/22/2011 76 Female 12/29/2011 Physician Germany
Primary
Secondary
Suicide Attempt Other Serious 12/22/2011 76 Female 12/30/2011 Other Health Professional Germany
Primary
Secondary
Femoral Artery Occlusion Hospitalization 12/1/2009 75 Male 149 lb 1/2/2012 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Hypotension Other Serious 12/22/2011 76 Female 1/9/2012 Physician Germany
Primary
Secondary
Suicide Attempt Other Serious 12/22/2011 76 Female 1/13/2012 Other Health Professional Germany
Primary
Secondary
Osteonecrosis Of Jaw Other Serious 80 Female 198 lb 1/24/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Jaw Other Serious 80 Female 198 lb 1/24/2012 Other Health Professional United Kingdom
Primary
Concomitant
Carotid Artery Stenosis Other Serious 12/1/2009 75 Male 149 lb 2/1/2012 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Vomiting Hospitalization 7/4/2011 74 Female 1/31/2012 Consumer Hong Kong
Primary
Secondary
Concomitant
Carotid Artery Stenosis Disability 12/1/2009 75 Male 143 lb 2/9/2012 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Drug Intolerance Other Serious 11/14/2011 83 Female 170 lb 2/14/2012 Consumer United States
Primary
Concomitant
Carotid Artery Stenosis Other Serious 12/1/2009 75 Male 142 lb 2/28/2012 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Hypotension Other Serious 12/22/2011 76 Female 3/1/2012 Physician Germany
Primary
Secondary
Arthropod Sting Hospitalization 7/4/2011 74 Female 2/29/2012 Hong Kong
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/14/2011 83 Female 170 lb 3/13/2012 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2010 70 Female 3/20/2012 Physician United States
Primary
Concomitant
Peripheral Coldness Hospitalization 3/7/2012 89 Female 3/21/2012 Consumer Brazil
Primary
Concomitant
Epistaxis 2/1/2012 78 Male 3/22/2012 Consumer United States
Primary
Concomitant
Vitreous Floaters Other Serious 1/1/2010 70 Female 3/26/2012 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 3/6/2012 70 Male 3/30/2012 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea 4/12/2012 United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 72 Female 125 lb 4/6/2012 Consumer United States
Primary
Concomitant
Lung Infection Hospitalization 3/1/2012 82 Female 4/11/2012 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased 5/1/2012 66 Male 175 lb 5/28/2012 Consumer United States
Primary
Concomitant
Electroencephalogram Abnormal Disability 3/7/2012 71 Female 5/25/2012 Pharmacist United Kingdom
Primary
Concomitant
Convulsion Life Threatening 71 Female 6/5/2012 Other Health Professional United Kingdom
Primary
Concomitant
Convulsion Other Serious 3/1/2012 77 Female 5/31/2012 Other Health Professional United Kingdom
Primary
Concomitant
Off Label Use Female 161 lb 7/3/2012 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Death 5/16/2012 72 Male 7/3/2012 Pharmacist Ireland
Primary
Concomitant
Interacting
Coronary Artery Disease Hospitalization 12/16/2010 69 Male 269 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Hallucination Other Serious 3/1/2012 86 Male 123 lb 7/31/2012 Consumer United Kingdom
Primary
Concomitant
Gastritis Erosive Hospitalization 3/16/2008 60 Male 8/6/2012 Physician Argentina
Primary
Concomitant

Drug Data