Busulfex combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Lesion Other Serious 0 Male 2/15/2007 Other Health Professional Turkey
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 1/1/2007 8 Male 88 lb 10/31/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 8/18/2007 8 Male 88 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease 10/23/2007 29 Female 4/2/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 3/25/2007 56 Male 4/2/2008 Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 12/22/2006 7 Female 72 lb 4/21/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Life Threatening 10/31/2007 50 Male 4/30/2008 Japan
Primary
Concomitant
Thrombotic Microangiopathy Life Threatening 2/6/2007 23 Male 4/30/2008 Japan
Primary
Concomitant
Mucosal Inflammation 11/9/2007 1 Male 4/30/2008 Japan
Primary
Secondary
Concomitant
Weight Increased Life Threatening 2/6/2007 55 Female 4/30/2008 Japan
Primary
Concomitant
Sepsis Life Threatening 10/8/2007 57 Female 5/15/2008 Other Health Professional Japan
Primary
Concomitant
Pneumonia Aspiration Hospitalization 12/20/2007 1 Male 5/15/2008 Physician Japan
Primary
Concomitant
Tumour Flare Life Threatening 10/30/2007 34 Male 5/15/2008 Physician Japan
Primary
Concomitant
Stomatitis Life Threatening 12/13/2006 30 Male 5/15/2008 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/6/2007 55 Female 5/15/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 10/21/2007 42 Male 6/6/2008 Japan
Primary
Concomitant
Thrombotic Microangiopathy Death 50 Female 6/6/2008 Israel
Primary
Concomitant
Thrombotic Microangiopathy Death 40 Male 6/6/2008 France
Primary
Concomitant
Visual Disturbance Hospitalization 30 Female 6/6/2008 Other Health Professional France
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 44 Male 6/6/2008 Argentina
Primary
Concomitant
Thrombotic Microangiopathy Death 34 Male 6/6/2008 Israel
Primary
Concomitant
Respiratory Failure Death 23 Female 6/6/2008 Switzerland
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 37 Male 6/6/2008 Israel
Primary
Concomitant
Tachycardia Life Threatening 12/13/2006 30 Male 6/11/2008 Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 7/1/2007 50 Male 6/19/2008 Japan
Primary
Concomitant
Acute Myeloid Leukaemia Recurrent Life Threatening 1/22/2008 26 Female 6/27/2008 Other Health Professional Japan
Primary
Concomitant
Oral Disorder Death 45 Female 6/27/2008 Other Health Professional Japan
Primary
Concomitant
Septic Shock Death 1/15/2007 44 Male 6/30/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Life Threatening 10/23/2007 50 Male 7/1/2008 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 2/29/2008 1 Female 7/2/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 2/6/2008 1 Female 7/2/2008 Japan
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 10/22/2007 32 Female 7/8/2008 Japan
Primary
Concomitant
Vomiting Hospitalization 7/24/2007 58 Male 7/8/2008 Japan
Primary
Concomitant
Stomatitis Hospitalization 8/31/2007 60 Male 7/10/2008 Japan
Primary
Concomitant
Stomatitis 2/3/2008 3 Female 7/16/2008 Japan
Primary
Concomitant
Grand Mal Convulsion Life Threatening 2/17/2007 5 Female 7/16/2008 Japan
Primary
Concomitant
Stomatitis Life Threatening 11/30/2007 50 Male 7/16/2008 Japan
Primary
Concomitant
Hypertrophic Cardiomyopathy 5/15/2008 1 Male 7/17/2008 Other Health Professional Japan
Primary
Concomitant
Nausea Death 6/27/2007 47 Female 7/17/2008 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 6/12/2007 51 Male 7/17/2008 Other Health Professional Japan
Primary
Concomitant
Transplant Rejection 12/27/2006 13 Female 7/18/2008 Japan
Primary
Concomitant
Stomatitis 2/21/2008 6 Female 7/18/2008 Japan
Primary
Concomitant
Stomatitis Life Threatening 12/5/2007 42 Male 7/25/2008 Japan
Primary
Concomitant
Febrile Neutropenia Life Threatening 4/5/2007 28 Male 8/5/2008 Japan
Primary
Concomitant
Vomiting 11/30/2007 9 Male 8/14/2008 Other Health Professional Japan
Primary
Concomitant
Stomatitis 5/23/2007 29 Female 8/14/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 4/17/2007 40 Female 8/14/2008 Other Health Professional Japan
Primary
Concomitant
Venoocclusive Liver Disease Death 4/10/2008 56 Female 8/18/2008 Japan
Primary
Concomitant
Stomatitis Hospitalization 5/27/2007 53 Female 8/22/2008 Japan
Primary
Concomitant
Vomiting Hospitalization 1/3/2008 7 Male 8/29/2008 Japan
Primary
Concomitant
Vomiting Death 3/28/2007 2 Female 9/4/2008 Japan
Primary
Concomitant
Transplant Failure Life Threatening 5/23/2007 55 Female 9/8/2008 Japan
Primary
Concomitant
Vomiting Hospitalization 1/11/2007 8 Male 9/8/2008 Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 3/14/2007 35 Female 9/10/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 12/23/2007 48 Male 9/9/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 12/16/2006 50 Male 9/9/2008 Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/15/2007 52 Male 9/11/2008 Other Health Professional Japan
Primary
Concomitant
Stomatitis Life Threatening 2/3/2008 3 Female 9/11/2008 Other Health Professional Japan
Primary
Concomitant
Mallory-weiss Syndrome Death 4/27/2007 47 Male 9/16/2008 Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 7/29/2007 28 Male 9/16/2008 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/23/2007 31 Male 9/16/2008 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/8/2006 51 Female 9/17/2008 Japan
Primary
Concomitant
Stem Cell Transplant Life Threatening 7/26/2007 49 Male 9/17/2008 Japan
Primary
Concomitant
Stomatitis Life Threatening 11/22/2007 50 Male 9/19/2008 Japan
Primary
Concomitant
Sepsis Death 57 Female 9/19/2008 Japan
Primary
Concomitant
Stomatitis Life Threatening 12/27/2006 13 Female 9/23/2008 Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 19 Male 9/26/2008 Germany
Primary
Concomitant
Vomiting Death 8/30/2006 46 Male 10/13/2008 Japan
Primary
Concomitant
T-cell Lymphoma Recurrent 1/21/2008 33 Male 10/16/2008 Japan
Primary
Concomitant
Tubulointerstitial Nephritis 8/9/2007 11 Male 10/16/2008 Germany
Primary
Concomitant
Liver Function Test Abnormal Death 8/30/2006 46 Male 10/20/2008 Japan
Primary
Concomitant
Vomiting Death 11/30/2006 11 Male 10/17/2008 Japan
Primary
Concomitant
Multi-organ Failure Death 8/17/2007 44 Female 10/28/2008 Japan
Primary
Concomitant
Stomatitis Hospitalization 12/25/2007 53 Male 11/11/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 12/16/2006 50 Male 11/14/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 4/25/2007 16 Male 11/14/2008 Japan
Primary
Secondary
Concomitant
Stomatitis Life Threatening 6/4/2007 44 Female 11/24/2008 Japan
Primary
Concomitant
Nausea Death 6/27/2007 47 Female 11/25/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 2/10/2007 0 Female 12/4/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 7/24/2007 58 Male 12/3/2008 Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/5/2007 53 Male 12/3/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 2/10/2007 0 Female 12/9/2008 Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/15/2007 52 Male 12/11/2008 Japan
Primary
Secondary
Concomitant
Stomatitis Life Threatening 12/28/2007 43 Female 12/16/2008 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/16/2006 50 Male 12/16/2008 Japan
Primary
Concomitant
Renal Failure Hospitalization 9/3/2007 29 Female 12/23/2008 Japan
Primary
Concomitant
Stomatitis Life Threatening 6/4/2007 44 Female 12/29/2008 Japan
Primary
Concomitant
Vomiting Death 24 Male 1/22/2009 Japan
Primary
Concomitant
Respiratory Failure Life Threatening 16 Male 2/3/2009 Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/15/2007 52 Male 2/3/2009 Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 8/2/2007 29 Female 2/3/2009 Japan
Primary
Concomitant
Toxic Encephalopathy Life Threatening 7/4/2007 51 Male 2/3/2009 Japan
Primary
Secondary
Concomitant
Stomatitis Disability 10/11/2007 58 Female 2/6/2009 Japan
Primary
Concomitant
Transplant Rejection 12 Male 2/6/2009 Turkey
Primary
Concomitant
Nausea Life Threatening 6/27/2007 47 Female 2/6/2009 Japan
Primary
Concomitant
Multi-organ Failure Death 8/17/2007 44 Female 3/19/2009 Japan
Primary
Concomitant
Upper Respiratory Tract Infection 16 5/21/2009 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia 8 Male 5/21/2009 United Kingdom
Primary
Concomitant
Procedural Complication 5 5/21/2009 France
Primary
Concomitant
Obliterative Bronchiolitis 4 6/3/2009 France
Primary
Concomitant
Mucoepidermoid Carcinoma 13 Male 6/4/2009 Korea, Republic Of
Primary
Secondary
Pulmonary Oedema Death 18 6/12/2009 France
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 50 Male 6/18/2009 Greece
Primary
Secondary
Concomitant
Anti-thyroid Antibody Positive 3 6/18/2009 France
Primary
Concomitant
Intracranial Venous Sinus Thrombosis 42 Female 6/30/2009 Japan
Primary
Concomitant
Graft Versus Host Disease 1/1/2004 7 Female 7/10/2009 Spain
Primary
Concomitant
Stomatitis 42 Female 7/10/2009 Japan
Primary
Concomitant
Acute Respiratory Distress Syndrome Death 14 Male 9/25/2009 France
Primary
Concomitant
Graft Versus Host Disease Death 20 Male 9/25/2009 France
Primary
Concomitant
Encephalitis Death 15 Male 9/25/2009 France
Primary
Concomitant
Venoocclusive Disease Death 56 9/29/2009 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 68 9/29/2009 United States
Primary
Secondary
Concomitant
Mucosal Inflammation 5 Male 10/1/2009 Italy
Primary
Concomitant
Drug Interaction 2 Unknown 11/12/2009 France
Primary
Secondary
Venoocclusive Disease Death 0 Unknown 11/12/2009 France
Primary
Concomitant
Venoocclusive Liver Disease 1 Female 12/1/2009 Japan
Primary
Concomitant
Respiratory Syncytial Virus Bronchiolitis Other Serious 1 Male 12/9/2009 Other Health Professional United States
Primary
Concomitant
Venoocclusive Liver Disease 1 Female 12/14/2009 Japan
Primary
Concomitant
Venoocclusive Liver Disease 6 Male 12/21/2009 Japan
Primary
Concomitant
Transplant Failure Other Serious 1/27/2010 Female 230 lb 2/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoxia Death 2/4/2010 Female 230 lb 2/5/2010 Other Health Professional United States
Primary
Secondary
Transplant Failure Death 2/4/2010 Female 230 lb 2/8/2010 Other Health Professional United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 51 Female 3/4/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease 6 Male 2/26/2010 Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 51 Female 3/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 21 Female 3/3/2010 Japan
Primary
Concomitant
Thrombotic Microangiopathy Death 12/10/2008 51 Female 3/3/2010 Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease 11/9/2008 6 Male 3/9/2010 Japan
Primary
Concomitant
Venoocclusive Liver Disease Death 21 Female 3/10/2010 Japan
Primary
Concomitant
Scleroderma Other Serious 61 Female 3/19/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Pleural Effusion Death 11 Female 3/15/2010 Turkey
Primary
Concomitant
Vomiting 42 Female 3/15/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2008 Female 93 lb 3/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 2/1/2009 56 Male 3/25/2010 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Other Serious 1 Female 3/26/2010 Other Health Professional India
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 52 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 2/1/2009 56 Male 3/31/2010 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Other Serious 52 Male 4/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 4/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Hepatotoxicity Other Serious 4/6/2010 Other Health Professional United States
Primary
Secondary
Hepatotoxicity Other Serious 4/6/2010 Other Health Professional United States
Primary
Secondary
Hepatotoxicity Other Serious 4/6/2010 Other Health Professional United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 4/6/2010 Other Health Professional United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 4/6/2010 Other Health Professional United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 4/6/2010 Other Health Professional United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 4/6/2010 Other Health Professional United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 4/6/2010 Other Health Professional United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 4/6/2010 Other Health Professional United States
Primary
Secondary
Therapeutic Agent Toxicity Death 22 Male 4/2/2010 Iran (Islamic Republic Of)
Primary
Concomitant
Testis Cancer Male 4/1/2010 Australia
Primary
Concomitant

Drug Data